Advanced search
Publication Cover
Experimental Lung Research Volume 45, 2019 - Issue 3-4
Submit an article Journal homepage
100
Views
3
CrossRef citations to date
0
Altmetric
Articles

Beryllium inhibits apoptosis via mitochondria in beryllium-induced lung disease in the rat

Zhihong LiuSchool of Public Health, Health Science Center of Xi’an Jiaotong University, Xi’an, P.R. China; ;NHC Key Laboratory of Trace Elements and Endemic Diseases, Xi’an Jiaotong University, Xi’an, P.R. China; ;School of Public Health and Management, Ningxia Medical University, Yinchuan, Ningxia, P.R. China; View further author information
,
Kai WangSchool of Public Health and Management, Ningxia Medical University, Yinchuan, Ningxia, P.R. China; View further author information
,
Qing YanSchool of Basic Medicine, Ningxia Medical University, Yinchuan, Ningxia, P.R. China; View further author information
,
Hejing WangSchool of Public Health and Management, Ningxia Medical University, Yinchuan, Ningxia, P.R. China; View further author information
,
Na ZhangSchool of Public Health and Management, Ningxia Medical University, Yinchuan, Ningxia, P.R. China; View further author information
,
Aihong GongGeneral Hospital of Ningxia Medical University, Yinchuan, Ningxia, P.R. ChinaView further author information
&
Xiong GuoSchool of Public Health, Health Science Center of Xi’an Jiaotong University, Xi’an, P.R. China; ;NHC Key Laboratory of Trace Elements and Endemic Diseases, Xi’an Jiaotong University, Xi’an, P.R. China; Correspondence[email protected]
View further author information
 show all
Pages 92-100 | Received 07 Mar 2019, Accepted 16 May 2019, Published online: 01 Jun 2019

References

  • Infante PF, Newman LS. Beryllium exposure and chronic beryllium disease. Lancet. 2004;363(9407):415–416. doi:10.1016/S0140-6736(04)15523-2.
  • Cooper RG, Harrison AP. The uses and adverse effects of beryllium on health. Indian J Occup Environ Med. 2009;13(2):65–76. doi:10.4103/0019-5278.55122.
  • Sanderson WT, Ward EM, Steenland K, Petersen MR. Lung cancer case-control study of beryllium workers. Am J Ind Med. 2001;39(2):133–144. doi:10.1002/1097-0274(200102)39:2<133::AID-AJIM1001>3.0.CO;2-7.
  • Schubauer-Berigan MK, Deddens JA, Couch JR, Petersen MR. Risk of lung cancer associated with quantitative beryllium exposure metrics within an occupational cohort. Occup Environ Med. 2011;68(5):354–360. doi:10.1136/oem.2010.056515.
  • Misra UK, Gawdi G, Pizzo SV. Beryllium fluoride-induced cell proliferation: a process requiring P21(ras)-dependent activated signal transduction and NF-kappaB-dependent gene regulation. J Leukoc Biol. 2002;71:487–494.
  • Belinsky SA, Snow SS, Nikula KJ, Finch GL, Tellez CS, Palmisano WA. Aberrant CpG island methylation of the p16(INK4a) and estrogen receptor genes in rat lung tumors induced by particulate carcinogens. Carcinogenesis. 2002;23(2):335–339. doi:10.1093/carcin/23.2.335.
  • Sawyer RT, Dobis DR, Goldstein M, et al. Beryllium-stimulated reactive oxygen species and macrophage apoptosis. Free Radic Biol Med. 2005;38(7):928–937. doi:10.1016/j.freeradbiomed.2004.12.014.
  • Huang L, Wang SJ, Luo JJ, Zhang ZH. Study on high permeabilized opening of lung mitochondrial permeability transition pore and apoptosis induced by beryllium sulfate in mice. J Toxicol. 2015;29:19–22.
  • Davies TA, Harding HE. Beryllium granulomata in the lungs of rats. Br J Ind Med. 1950;7:70–72. doi:10.1136/oem.7.2.70.
  • Shi WL. Study of dose correlation on experimental beryllium. Indus Health and Occup Dis. 1986;:2:65–67.
  • Labelle CW, Cucci MR. Preliminary studies in the toxicity of beryllium; the effect of intratracheal injection of beryllium in experimental animals. At Energy Biophys Biol Med. 1948;1:182.
  • Sisson TH, Mendez M, Choi K, et al. Targeted injury of type II alveolar epithelial cells induces pulmonary fibrosis. Am J Respir Crit Care Med. 2010;181(3):254–263. doi:10.1164/rccm.200810-1615OC.
  • Mei Y, Stonestrom A, Hou YM, Yang X. Apoptotic regulation and tRNA. Protein Cell. 2010;1(9):795–801. doi:10.1007/s13238-010-0107-x.
  • Gorjala P. Characterization of Beryllium as a Novel Agent to Study Cell Cycle Arrest and Cellular Senescence Las Vegas [Dissertations]. Las Vegas, NV: University of Nevada; 2012.
  • Sun M, Jiang JG, Zhang XY, et al. Expression of apoptosis-associated gene caspase-3 in human non-small-cell lung cancer and its clinical significance study. Chin J Gerontol. 2014:17–19.
  • Apolinario RM, van der Valk P, de Jong JS, et al. Prognostic value of the expression of p53, bcl-2, and bax oncoproteins, and neovascularization in patients with radically resected non-small-cell lung cancer. J Clin Oncol. 1997;15(6):2456–2466. doi:10.1200/JCO.1997.15.6.2456.
  • Brambilla E, Gazzeri S, Lantuejoul S, et al. p53 mutant immunophenotype and deregulation of p53 transcription pathway (Bcl2, Bax, and Waf1) in precursor bronchial lesions of lung cancer. Clin Cancer Res. 1998;4:1609–1618.
  • Coates SS, Lehnert BE, Sharma S, Kindell SM, Gary RK. Beryllium induces premature senescence in human fibroblasts. J Pharmacol Exp Ther. 2007;322(1):70–79. doi:10.1124/jpet.106.118018.
  • Devarajan E, Sahin AA, Chen JS, et al. Down-regulation of caspase 3 in breast cancer: a possible mechanism for chemoresistance. Oncogene. 2002;21(57):8843–8851. doi:10.1038/sj.onc.1206044.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.