HCV has Transforming Potential to Retrovirus: An Ultrastructure Hypothesis

References

• Montalbano M, Kemmer N, Neff GW. Managing chronic hepatitis C in relapsers and non-responders. Minerva Gastroenterol Dietol 2008; 54: 31–47
   PubMedGoogle Scholar
• Zaki Mel S, Auf FA, Ghawalby NA, Saddal NM. Clinical significance of serum soluble Fas, Fas ligand and fas in intrahepatic lymphocytes in chronic hepatitis C. Immunol Invest 2008; 37: 163–170
   PubMedGoogle Scholar
• Blanchard E, Christophe H, Brand D, et al. Hepatitis C virus like particle budding: role of the core protein and importance of its ASP. J Virol 2003; 77: 10131–10138
   PubMedGoogle Scholar
• Pietschmann T, Kaul A, Koutsoudakis G, et al. Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras. Proc Natl Acad Sci USA 2006; 103: 7408–7413
   PubMed Web of Science ®Google Scholar
• Gastaminza P, Kapadia SB, Chisari FV. Differential biophysical properties of infectious intracellular and secreted hepatitis C virus particles. J Virol 2006; 80: 11074–11081
   PubMed Web of Science ®Google Scholar
• Guo J, Yan R, Xu G, Li W, Zheng C. Construction of the Vero cell culture system that can produce infectious HCV particles. Mol Biol Rep 2007; 25: 1345–1348
   Google Scholar
• Roingeard P, Hourioux C, Blanchard E, Brand D, Ait-Goughoulte M. Hepatitis C virus ultrastructure and morphogenesis. Biol Cell 2004; 96: 103–108
   PubMedGoogle Scholar
• Hourioux C, Ait-Goughoulte M, Patient R, et al. Core protein domains involved in hepatitis C virus-like particle assembly and budding at the endoplasmic reticulum membrane. Cell Microbiol 2006; 6: 1725–1729
   Google Scholar
• De Vos R, Verslype C, Depla E, Fevery J, Van Damme B, Desamet V, Roskams T. Ultrastructure visualization of hepatitis C virus components in human and primate liver biopsies. J Hepatol 2002; 37: 370–379
   PubMedGoogle Scholar
• Kasprzak A, Biczysko W, Adamek A, Zabel M. Morphological lesions detected by light and electron microscopies in chronic type C hepatitis. Pol J Pathol 2003; 54: 129–142
   PubMedGoogle Scholar
• Miyanari Y, Atsuzawa K, Usuda N, et al. The lipid droplet is an important organelle for hepatitis C virus production. Nat Cell Biol 2007; 9: 1089–1097
   PubMed Web of Science ®Google Scholar
• Desmet VJ, Gerber M, Hoofnfnagle JH, Manns M, Scheur PJ. Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology 1994; 19: 1513–1520
   PubMed Web of Science ®Google Scholar
• Schwer B, Ren S, Pietschmann T, et al. Targeting of hepatitis C virus core protein to mitochondria through a novel C-terminal localization motif. J Virol 2004; 78: 7958–7968
   PubMed Web of Science ®Google Scholar
• Lindenbach BD, Evans MJ, Syder AJ, et al. Complete replication of hepatitis C virus in cell culture. Science 2005; 309: 623–626
   PubMed Web of Science ®Google Scholar
• Wakita T, Pietschmann T, Kato T, et al. Production of infectious hepatitis C virus in tissue culture from a cloned viral genome. Nat Med 2005; 11: 791–796
   PubMed Web of Science ®Google Scholar
• Zhong J, Gastaminza P, Cheng G, et al. Robust hepatitis C virus infection in vitro. Proc Natl Acad Sci USA 2005; 102: 9294–9299
   PubMed Web of Science ®Google Scholar
• Yu X, Qiao M, Atanasov I, et al. Cryo-electron microscopy and three-dimensional reconstructions of hepatitis C virus particles. Virology 2007; 367: 126–134
   PubMed Web of Science ®Google Scholar
• Targett-Adams P, Boulant S, McLauchlan J. Visualization of double-stranded RNA in cells supporting hepatitis C virus RNA replication. J Virol 2008; 82: 2182–2195
   PubMed Web of Science ®Google Scholar
• Ishida S, Kaito M, Kohara M, et al. Hepatitis C virus core particle detected by immunoelectron microscopy and optical rotation technique. Hepatol Res 2001; 20: 335–347
   PubMedGoogle Scholar
• Kaito M, Watanabe S, Tanaka H, et al. Morphological identification of hepatitis C virus E1 and E2 envelope glycoproteins on the virion surface using immunogold electron microscopy. Int J Mol Med 2006; 18: 673–678
   PubMedGoogle Scholar
• Tortora GJ, Funke BR, Case CL. Viruses, viroids, and prions. Microbiology: An Introduction, C Benjamin. Pearson Education Schweiz, Zug, Switzerland 2003; 376–407
   Google Scholar
• Goff SP. Retroviridae: the retroviruses and their replication. Fields Virology, DM Knipe, DE Griffin, RA Lamb, et al. Lippincott Williams & Wilkins, Philadelphia 2007; 2000–2051
   Google Scholar
• Ruigrok RWH, Schoehn G, Conway JF. The morphology and structure of viruses. Topley Wilson's Microbiology & Microbial Infections, Vol 2: Virology, BWJ Mahy, VT Meulen. Hodder Arnold, London 2005; 57–79
   Google Scholar
• Roehrig JT, Gubler DJ. Flaviviruses. Topley Wilson's Microbiology and Microbial Infections: Virology, BWJ Mahy, VT Meulen. Hodder Arnold, London 2005; 993–1005
   Google Scholar
• Roingeard P, Hourioux C. Hepatitis C virus core protein, lipid droplets and steatosis. J Viral Hepat 2008; 15: 157–164
   Google Scholar
• Perez-Carreras M, Del Hoyo P, Martin M, Rubio JC. Defective hepatic mitochondrial respiratory chain in patients with non-alcoholic steatohepatitis. Hepatology 2003; 38: 999–1007
   PubMed Web of Science ®Google Scholar
• Mansy SS, Nessim IG, Sadek A. Mitochondrial cytochrome C and ultrastructural changes in hepatic steatosis induced by hepatitis C virus. New Egyptian J Med 2005; 33: 74–79
   Google Scholar
• Gastaminza P, Kapadia SB, Chisari FV. Differential biophysical properties of infectious intracellular and secreted hepatitis C virus particles. J Virol 2006; 80: 11074–11081
   PubMed Web of Science ®Google Scholar