Electron microscopy in renal pathology: overall applications and guidelines for tissue, collection, preparation, and stains

References

• Caulfield JB. Application of the electron microscope to renal diseases. N Engl J Med. 1964;270(4):183–194. doi:10.1056/NEJM196401232700406.
   PubMed Web of Science ®Google Scholar
• Ben-Bassat M, Stark H, Robson M, Rosenfeld J. Value of routine electron microscopy in the differential diagnosis of the nephrotic syndrome. Pathol Microbiol. 1974; 41(1):26–40.
   PubMedGoogle Scholar
• Haas M. A reevaluation of routine electron microscopy in the examination of native renal biopsies. J Am Soc Nephrol. 1997;8:70–76.
   PubMed Web of Science ®Google Scholar
• Mandal AK, Chieu TT, Nordquist JA, Owen WL, Wenzl JE. Analysis of the value of electron microscopy study in the practice of nephrology. Pathol Annual. 1979; 14(Pt 1):83–121.
   PubMedGoogle Scholar
• Muehrcke RC, Mandal AK, Gotoff SP, Isaacs EW, Volini FI. The clinical value of electron microscopy in renal disease. Archives Internal Med. 1969;124(2):170–176. doi:10.1001/archinte.1969.00300180042008.
   PubMedGoogle Scholar
• Pearson JM, McWilliam LJ, Coyne JD, Curry A. Value of electron microscopy in diagnosis of renal disease. J Clin Pathol. 1994;47(2):126–128. doi:10.1136/jcp.47.2.126.
   PubMed Web of Science ®Google Scholar
• Rivera A, Magliato S, Meleg-Smith S. Value of electron microscopy in the diagnosis of childhood nephrotic syndrome. Ultrastruct Pathol. 2001;25(4):313–320. doi:10.1080/019131201753136340.
   PubMed Web of Science ®Google Scholar
• Siegel NJ, Spargo BH, Kashgarian M, Hayslett JP. An evaluation of routine electron microscopy in the examination of renal biopsies. Nephron. 1973;10(4):209–215. doi:10.1159/000180189.
   PubMed Web of Science ®Google Scholar
• Silva FG, Pirani CL. Electron microscopic study of medical diseases of the kidney: update–1988. Modern Pathol. 1988; 1(4):292–315.
   PubMed Web of Science ®Google Scholar
• Tighe JR, Jones NF. The diagnostic value of routine electron microscopy of renal biopsies. Proc R Soc Med. 1970;63(5):475–477. doi:10.1177/003591577006300528.
   PubMedGoogle Scholar
• Olsen S, Bohman SO, Hestbech J, et al. Ultrastructural lesions in lightmicroscopically defined types of glomerulonephritis. A blind and semiquantitative study. Acta Pathol Microbiol Immunol Scandinavica Sec A Pathol. 1983;91(1):53–63.
   PubMedGoogle Scholar
• Spargo BH. Practical use of electron microscopy for the diagnosis of glomerular disease. Hum Pathol. 1975;6(4):405–420. doi:10.1016/S0046-8177(75)80060-8.
   PubMed Web of Science ®Google Scholar
• Nasr SH, Markowitz GS, Valeri AM, Yu Z, Chen L, D’Agati VD. Thin basement membrane nephropathy cannot be diagnosed reliably in deparaffinized, formalin-fixed tissue. Nephrol Dialysis Transplantation. 2007;22(4):1228–1232. doi:10.1093/ndt/gfl838.
   PubMed Web of Science ®Google Scholar
• Bretschneider A, Burns W, Morrison A. “Pop-off” technic. The ultrastructure of paraffin-embedded sections. Am J Clin Pathol. 1981;76(4):450–453. doi:10.1093/ajcp/76.4.450.
   PubMed Web of Science ®Google Scholar
• Satoskar AA, Calomeni E, Bott C, Nadasdy GM, Nadasdy T. Focal glomerular immune complex deposition: possible role of periglomerular fibrosis/atubular glomeruli. Arch Pathol Lab Med. 2009;133:283–288.
   PubMed Web of Science ®Google Scholar
• Pavlisko EN, Howell DN. The continued vital role of electron microscopy in the diagnosis of renal disease/dysfunction. Ultrastruct Pathol. 2013;37(1):1–8. doi:10.3109/01913123.2012.670025.
   PubMed Web of Science ®Google Scholar
• Howell DN, Smith SR, Butterly DW, et al. Diagnosis and management of BK polyomavirus interstitial nephritis in renal transplant recipients. Transplantation. 1999;68(9):1279–1288. doi:10.1097/00007890-199911150-00011.
   PubMed Web of Science ®Google Scholar
• Henriksen KJ, Meehan SM, Chang A. Non-neoplastic renal diseases are often unrecognized in adult tumor nephrectomy specimens: a review of 246 cases. Am J Surg Pathol. 2007;31(11):1703–1708. doi:10.1097/PAS.0b013e31804ca63e.
   PubMed Web of Science ®Google Scholar
• Salvatore SP, Cha EK, Rosoff JS, Seshan SV. Nonneoplastic renal cortical scarring at tumor nephrectomy predicts decline in kidney function. Arch Pathol Lab Med. 2013;137(4):531–540. doi:10.5858/arpa.2012-0070-OA.
   PubMed Web of Science ®Google Scholar
• Howell DN, Gu X, Herrera GA. Organized deposits in the kidney and look-alikes. Ultrastruct Pathol. 2003;27(5):295–312. doi:10.1080/01913120390231555.
   PubMed Web of Science ®Google Scholar
• Doi T, Kanatsu K, Nagai H, Kohrogi N, Kuwahara T, Hamashima Y. Immunoelectron microscopic studies of IgA nephropathy. Nephron. 1984;36(4):246–251. doi:10.1159/000183163.
   PubMed Web of Science ®Google Scholar
• Dysart NK Jr., Sisson S, Vernier RL. Immunoelectron microscopy of IgA nephropathy. Clin Immunol Immunopathol. 1983;29(2):254–270. doi:10.1016/0090-1229(83)90028-4.
   PubMedGoogle Scholar
• Herrera GA. The contributions of electron microscopy to the understanding and diagnosis of plasma cell dyscrasia-related renal lesions. Med Electron Microscopy. 2001;34(1):1–18. doi:10.1007/s007950100000.
   PubMedGoogle Scholar
• Herrera GA. Renal lesions associated with plasma cell dyscrasias: practical approach to diagnosis, new concepts, and challenges. Arch Pathol Lab Med. 2009;133:249–267.
   PubMed Web of Science ®Google Scholar
• Herrera GA. Proximal tubulopathies associated with monoclonal light chains: the spectrum of clinicopathologic manifestations and molecular pathogenesis. Arch Pathol Lab Med. 2014;138(10):1365–1380. doi:10.5858/arpa.2013-0493-OA.
   PubMed Web of Science ®Google Scholar
• Herrera GA, Turbat-Herrera EA. Ultrastructural immunolabeling in the diagnosis of monoclonal light-and heavy-chain-related renal diseases. Ultrastruct Pathol. 2010;34(3):161–173. doi:10.3109/01913121003672873.
   PubMed Web of Science ®Google Scholar
• Herrera GA, Turbat-Herrera EA, Viale G, et al. Ultrastructural immunolabeling in renal diseases. Past, present and future expectations. Pathol Immunopathol Res. 1987;6(1):51–63. doi:10.1159/000157041.
   PubMedGoogle Scholar
• Rantala I, Helin H. Immunoelectron microscopic localization of immunoglobulins and complement in human renal glomeruli. J Histochem Cytochem. 1982;30(9):932–937. doi:10.1177/30.9.7130673.
   PubMed Web of Science ®Google Scholar
• Smith PS. Ultrastructural immuno-gold localization of immune deposits in human renal biopsies. Pathology. 1988;20(1):32–37. doi:10.3109/00313028809085193.
   PubMed Web of Science ®Google Scholar
• Veeramachaneni R, Gu X, Herrera GA. Atypical amyloidosis: diagnostic challenges and the role of immunoelectron microscopy in diagnosis. Ultrastruct Pathol. 2004;28(2):75–82. doi:10.1080/01913120490430436.
   PubMed Web of Science ®Google Scholar
• Herrera GA. Ultrastructural immunolabeling: a general overview of techniques and applications. Ultrastruct Pathol. 1992;16(1–2):37–45. doi:10.3109/01913129209074548.
   PubMed Web of Science ®Google Scholar
• Herrera GA, Lott RL. Colloidal gold labeling in diagnostic pathology. Hayat MA, ed. Colloidal Gold: Principles, Methods, and Applications. Vol. 3. San Diego and London: Academic Press. 1990; 321–345.
   Google Scholar
• Bendayan M, Nanci A, Kan FW. Effect of tissue processing on colloidal gold cytochemistry. J Histochem Cytochem. 1987;35(9):983–996. doi:10.1177/35.9.3302022.
   PubMed Web of Science ®Google Scholar
• Bendayan M, Zollinger M. Ultrastructural localization of antigenic sites on osmium-fixed tissues applying the protein A-gold technique. J Histochem Cytochem. 1983;31(1):101–109. doi:10.1177/31.1.6187796.
   PubMed Web of Science ®Google Scholar