Grape seed extract protects against amiodarone - induced nephrotoxicity and ultrastructural alterations associated with the inhibition of biomarkers of inflammation and oxidative stress in rats

References

• Wu H, Huang J. Drug-induced nephrotoxicity: pathogenic mechanisms, biomarkers and prevention strategies. Curr Drug Metab. 2018;19(7):559–567. doi:10.2174/1389200218666171108154419.
   PubMed Web of Science ®Google Scholar
• Nuttall SL, Routledge HC, Kendall MJ. A comparison of the beta1-selectivity of three beta1-selective beta-blockers. J Clin Pharm Ther. 2003;28(3):179–186. doi:10.1046/j.1365-2710.2003.00477.x.
   PubMed Web of Science ®Google Scholar
• Kawabata M, Hirao K, Hachiya H, et al. Role of oral amiodarone in patients with atrial fibrillation and congestive heart failure. J Cardiol. 2011;58(2):108–115. doi:10.1016/j.jjcc.2011.06.005.
   PubMed Web of Science ®Google Scholar
• Lafuente-Lafuente C, Alvarez JC, Leenhardt A, et al. Amiodarone concentrations in plasma and fat tissue during chronic treatment and related toxicity. Br J Clin Pharmacol. 2009;67(5):511–519. doi:10.1111/j.1365-2125.2009.03381.x.
   PubMed Web of Science ®Google Scholar
• Primeau R, Agha A, Giorgi C, Shenasa M, Nadeau R. Long term efficacy and toxicity of amiodarone in the treatment of refractory cardiac arrhythmias. Can J Cardiol. 1989;5:98–104.
   PubMed Web of Science ®Google Scholar
• Kolettis TM, Agelaki MG, Baltogiannis GG, et al. Comparative effects of acute vs. chronic oral amiodarone treatment during acute myocardial infarction in rats. Europace. 2007;9(11):1099–1104. doi:10.1093/europace/eum196.
   PubMed Web of Science ®Google Scholar
• Sakr SA, El-Gamal EM. Effect of grapefruit juice on amiodarone induced nephrotoxicity in albino rats. Toxicol Ind Health. 2016;32(1):68–75. doi:10.1177/0748233713498443.
   PubMed Web of Science ®Google Scholar
• Somani P, Bandyopadhyay S, Klaunig JE, Gross SA. Amiodarone- and desethylamiodarone-induced myelinoid inclusion bodies and toxicity in cultured rat hepatocytes. Hepatology. 1990;11(1):81–92. doi:10.1002/hep.1840110115.
   PubMed Web of Science ®Google Scholar
• Ruch RJ, Bandyopadhyay S, Somani P, Klaunig JE. Evaluation of amiodarone free radical toxicity in rat hepatocytes. Toxicol Lett. 1991;56(1–2):117–126. doi:10.1016/0378-4274(91)90097-P.
   PubMed Web of Science ®Google Scholar
• Yin J, Yang M, Yu S, et al. Effect of acupuncture at Neiguan point combined with amiodarone therapy on early recurrence after pulmonary vein electrical isolation in patients with persistent atrial fibrillation. J Cardiovasc Electrophysiol. 2019;30(6):910–917. doi:10.1111/jce.13924.
   PubMed Web of Science ®Google Scholar
• Park SH, Park TS, Cha YS. Grape seed extract (Vitis vinifera) partially reverses high fat diet-induced obesity in C57BL/6J mice. Nutr Res Pract. 2008;2(4):227–233. doi:10.4162/nrp.2008.2.4.227.
   PubMedGoogle Scholar
• Garavaglia J, Markoski MM, Oliveira A, Marcadenti A. Grape seed oil compounds: biological and chemical actions for health. Nutr Metab Insights. 2016;9:59–64. doi:10.4137/NMI.S32910.
   PubMed Web of Science ®Google Scholar
• Sano T, Oda E, Yamashita T, et al. Antithrombotic effect of proanthocyanidin, a purified ingredient of grape seed. Thromb Res. 2005;115(1–2):115–121. doi:10.1016/j.thromres.2004.07.015.
   PubMed Web of Science ®Google Scholar
• Rasines-Perea Z, Teissedre PL. Grape polyphenols’ effects in human cardiovascular diseases and diabetes. Molecules. 2017;22(1):68–77. doi:10.3390/molecules22010068.
   Web of Science ®Google Scholar
• Liu W, Zhao S, Wang J, et al. Grape seed proanthocyanidin extract ameliorates inflammation and adiposity by modulating gut microbiota in high-fat diet mice. Mol Nutr Food Res. 2017;61(9). Eup 2017.
   Web of Science ®Google Scholar
• Abdel-Kawi SH, Hashem KS, Abd-Allah S. Mechanism of diethylhexylphthalate (DEHP) induced testicular damage and of grape seed extract-induced protection in the rat. Food Chem Toxicol. 2016;90:64–75. doi:10.1016/j.fct.2016.02.003.
   PubMed Web of Science ®Google Scholar
• Morales AI, Barata JD, Bruges M, et al. Acute renal toxic effect of amiodarone in rats. Pharmacol Toxicol. 2003;92(1):39–42. doi:10.1034/j.1600-0773.2003.920107.x.
   PubMedGoogle Scholar
• Agoston M, Cabello RG, Blázovics A, Fehér J, Vereckei A. The effect of amiodarone and/or antioxidant treatment on splenocyte blast transformation. Clin Chim Acta. 2001;303(1–2):87–94. doi:10.1016/S0009-8981(00)00383-1.
   PubMed Web of Science ®Google Scholar
• Serviddio G, Bellanti F, Giudetti AM, et al. Mitochondrial oxidative stress and respiratory chain dysfunction account for liver toxicity during amiodarone but not dronedarone administration. Free Radic Biol Med. 2011;51(12):2234–2242. doi:10.1016/j.freeradbiomed.2011.09.004.
   PubMed Web of Science ®Google Scholar
• Golli-Bennour EE, Bouslimi A, Zouaoui O, Nouira S, Achour A, Bacha H. Cytotoxicity effects of amiodarone on cultured cells. Exp Toxicol Pathol. 2012;64(5):425–430.doi:10.1016/j.etp.2010.10.008.
   PubMedGoogle Scholar
• Ray S, Bagchi D, Lim PM, et al. Acute and long-term safety evaluation of a novel IH636 grape seed proanthocyanidin extract. Res Commun Mol Pathol Pharmacol. 2001;109(3–4):165–197.
   PubMed Web of Science ®Google Scholar
• Joanta AE, Filip A, Clichici S, Andrei S, Daicoviciu D. Iodide excess exerts oxidative stress in some target tissues of the thyroid hormones. Acta physiologica Hungarica. 2006;93(4):347–359.doi:10.1556/APhysiol.93.2006.4.11.
   PubMedGoogle Scholar
• Shoyinka SV, Obidike IR, Ndumnego CO. Effect of iodine supplementation on thyroid and testicular morphology and function in euthyroid rats. Vet Res Commun. 2008;32(8):635–645. doi:10.1007/s11259-008-9065-7.
   PubMed Web of Science ®Google Scholar
• Gutowski M, Kowalczyk S. A study of free radical chemistry: their role and pathophysiological significance. Acta Biochim Pol. 2013;60(1):1–16. doi:10.18388/abp.2013_1944.
   PubMed Web of Science ®Google Scholar
• Karth GD, Buberl A, Nikfardjam M, et al. Role of amiodarone on the systemic inflammatory response induced by cardiac surgery: proinflammatory actions. Canadian journal of anaesthesia = Journal canadien d’anesthesie. 2007;54(4):262–268. doi:10.1007/BF03022770.
   PubMed Web of Science ®Google Scholar
• Llópiz N, Puiggròs F, Céspedes E, et al. Antigenotoxic effect of grape seed procyanidin extract in Fao cells submitted to oxidative stress. J Agric Food Chem. 2004;52(5):1083–1087. doi:10.1021/jf0350313.
   PubMed Web of Science ®Google Scholar
• Al Dera HS. Protective Effect of resveratrol against aluminum chloride induced nephrotoxicity in rats. Saudi Med J. 2016;37(4):369–378. doi:10.15537/smj.2016.4.13611.
   PubMed Web of Science ®Google Scholar
• Ray SD, Patel D, Wong V, Bagchi D. In vivo protection of DNA damage associated apoptotic and necrotic cell deaths during acetaminophen-induced nephrotoxicity, amiodarone-induced lung toxicity and doxorubicin-induced cardiotoxicity by a novel IH636 grape seed proanthocyanidin extract. Res Commun Mol Pathol Pharmacol. 2000;107(1–2):137–166.
   PubMedGoogle Scholar
• Mohanasundari M, Sabesan M, Sethupathy S. Renoprotective effect of grape seeds extract in ethylene glycol induced nephrotoxic mice. Indian J Exp Biol. 2005;43:356–359.
   PubMedGoogle Scholar