230
Views
7
CrossRef citations to date
0
Altmetric
Original Articles

Investigating the effect of transcutol on the physical properties of an O/W cream

, , , &
Pages 600-606 | Received 08 Jan 2019, Accepted 14 Apr 2019, Published online: 15 May 2019

References

  • Otto, A.; Du Plessis, J. The Effects of Emulsifiers and Emulsion Formulation Types on Dermal and Transdermal Drug Delivery. In Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement; Springer: New York, NY, 2015; pp. 223–241.
  • Shui, L.; van den Berg, A.; Eijkel, J. C. Interfacial Tension Controlled W/O and O/W 2-Phase Flows in Microchannel. Lab Chip. 2009, 9, 795–801. DOI: 10.1039/b813724b.
  • Nursakinah, I.; Ismail, A.; Rahimi, M.; Idris, A. Evaluation of HLB values of mixed non-ionic surfactants on the stability of oil-in-water emulsion system. AIP Conference Proceedings, 2013; pp. 850–856.
  • Meher, J. G.; Yadav, N. P.; Sahu, J. J.; Sinha, P. Determination of Required Hydrophilic–Lipophilic Balance of Citronella Oil and Development of Stable Cream Formulation. Drug Dev. Ind. Pharm. 2013, 39, 1540–1546. DOI: 10.3109/03639045.2012.719902.
  • Kamba, E.; Itodo, A.; Ogah, E. Utilization of Different Emulsifying Agents in the Preparation and Stabilization of Emulsions. Int. J. Mater. Chem. 2013, 3, 69–74.
  • Yadav, N. P.; Meher, J. G.; Pandey, N.; Luqman, S.; Yadav, K. S.; Chanda, D. Enrichment, Development, and Assessment of Indian Basil Oil Based Antiseptic Cream Formulation Utilizing Hydrophilic-Lipophilic Balance Approach. Biomed Res. Int. 2013, 2013, 1. DOI: 10.1155/2013/410686.
  • Xavier-Junior, F. H.; Huang, N.; Vachon, J.-J.; Rehder, V. L. G.; do Egito, E. S. T.; Vauthier, C. Match of Solubility Parameters between Oil and Surfactants as a Rational Approach for the Formulation of Microemulsion with a High Dispersed Volume of Copaiba Oil and Low Surfactant Content. Pharm. Res. 2016, 33, 3031–3043. DOI: 10.1007/s11095-016-2025-y.
  • Komaiko, J. S.; McClements, D. J. Formation of Food‐Grade Nanoemulsions Using Low‐Energy Preparation Methods: A Review of Available Methods. Comp. Rev. Food Sci. Food Safety. 2016, 15, 331–352. DOI: 10.1111/1541-4337.12189.
  • Savjani, K. T.; Gajjar, A. K.; Savjani, J. K. Drug Solubility: Importance and Enhancement Techniques. ISRN Pharma. 2012, 2012, 1. DOI: 10.5402/2012/195727.
  • Gupta, S.; Kesarla, R.; Omri, A. Formulation Strategies to Improve the Bioavailability of Poorly Absorbed Drugs with Special Emphasis on Self-Emulsifying Systems. ISRN Pharma. 2013, 2013, 1. DOI: 10.1155/2013/848043.
  • Kalepu, S.; Nekkanti, V. Insoluble Drug Delivery Strategies: Review of Recent Advances and Business Prospects. Acta Pharma. Sinica B. 2015, 5, 442–453. DOI: 10.1016/j.apsb.2015.07.003.
  • Fontenot, K.; Schork, F. J. Sensitivities of Droplet Size and Stability in Monomeric Emulsions. Ind. Eng. Chem. Res. 1993, 32, 373–385. DOI: 10.1021/ie00014a014.
  • van der Tuuk Opedal, N.; Sørland, G.; Sjöblom, J. Methods for Droplet Size Distribution Determination of Water-in-Oil Emulsions Using Low-Field NMR. Diffus. Fund. 2009, 7, 1–29.
  • Wang, Z.; Lin, X.; Rui, Z.; Xu, M.; Zhan, S. The Role of Shearing Energy and Interfacial Gibbs Free Energy in the Emulsification Mechanism of Waxy Crude Oil. Energies 2017, 10, 721. DOI: 10.3390/en10050721.
  • Denkova, P. S.; Tcholakova, S.; Denkov, N. D.; Danov, K. D.; Campbell, B.; Shawl, C.; Kim, D. Evaluation of the Precision of Drop-Size Determination in Oil/Water Emulsions by Low-Resolution NMR Spectroscopy. Langmuir 2004, 20, 11402–11413. DOI: 10.1021/la048649v.
  • Alteraifi, A. M. Effects of Solid–Liquid Interface on the Interfacial Tension Measured by Micropipet Technique. J. Colloid Interface Sci. 2005, 287, 226–232. DOI: 10.1016/j.jcis.2005.02.009.
  • Oehlke, K.; Garamus, V. M.; Heins, A.; Stöckmann, H.; Schwarz, K. The Partitioning of Emulsifiers in o/w Emulsions: A Comparative Study of SANS, Ultrafiltration and Dialysis. J. Colloid Interface Sci. 2008, 322, 294–303. DOI: 10.1016/j.jcis.2008.02.042.
  • James-Smith, M. A.; Alford, K.; Shah, D. O. A Novel Method to Quantify the Amount of Surfactant at the Oil/Water Interface and to Determine Total Interfacial Area of Emulsions. J. Colloid Interface Sci. 2007, 310, 590–598. DOI: 10.1016/j.jcis.2007.01.085.
  • Sullivan, D. W.; Jr, Gad, S. C.; Julien, M. A Review of the Nonclinical Safety of Transcutol®, a Highly Purified Form of Diethylene Glycol Monoethyl Ether (DEGEE) Used as a Pharmaceutical Excipient. Food Chem. Toxicol. 2014, 72, 40–50. DOI: 10.1016/j.fct.2014.06.028.
  • Lee, S. G.; Kang, J. B.; Kim, S. R.; Kim, C. J.; Yeom, D. W.; Yoon, H. Y.; Kwak, S. S.; Choi, Y. W. Enhanced Topical Delivery of Tacrolimus by a Carbomer Hydrogel Formulation with Transcutol P. Drug Dev. Ind. Pharma. 2016, 42, 1636–1642. DOI: 10.3109/03639045.2016.1160107.
  • Nastiti, C. M.; Ponto, T.; Abd, E.; Grice, J. E.; Benson, H. A.; Roberts, M. S. Topical Nano and Microemulsions for Skin Delivery. Pharmaceutics 2017, 9, 37. DOI: 10.3390/pharmaceutics9040037.
  • Chang, R.-K.; Raw, A.; Lionberger, R.; Yu, L. Generic Development of Topical Dermatologic Products: Formulation Development, Process Development, and Testing of Topical Dermatologic Products. AAPS J. 2013, 15, 41–52. DOI: 10.1208/s12248-012-9411-0.
  • Katdare, A.; Chaubal, M. Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems; CRC Press: Boca Rotan, FL, 2006.
  • Williams, S. O.; Long, S.; Allen, J.; Wells, M. L. Scale-Up of an Oil/Water Cream Containing 40% Diethylene Glycol monoethyl ether. Drug Dev. Ind. Pharm. 2000, 26, 71–77. DOI: 10.1081/DDC-100100329.
  • Selvakumar, R.; Dhinakaran, S. Effective Viscosity of Nanofluids- A Modified Krieger-Doughtery Model Based on Particle Size Distribution (PSD) Analysis. J. Mol. Liquids 2017, 225, 20–27. DOI: 10.1016/j.molliq.2016.10.137.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.