Design and optimization of liquisolid compact based vaginal sustained release tablet of antifungal agent for vaginal candidiasis

References

• Kenechukwu, F. C.; Attama, A. A.; Ibezim, E. C.; Nnamani, P. O.; Umeyor, C. E.; Uronnachi, E. M.; Gugu, T. H.; Momoh, M. A.; Ofokansi, K. C.; Akpa, P. A. Surface-Modified Mucoadhesive Microgels as a Controlled Release System for Miconazole Nitrate to Improve Localized Treatment of Vulvovaginal Candidiasis. Eur. J. Pharm. Sci. 2018, 111, 358–375. DOI: 10.1016/j.ejps.2017.10.002.
   PubMed Web of Science ®Google Scholar
• Yano, J.; Sobel, J. D.; Nyirjesy, P.; Sobel, R.; Williams, V. L.; Yu, Q.; Noverr, M. C.; Fidel, P. L. Current Patient Perspectives of Vulvovaginal Candidiasis: Incidence, Symptoms, Management and Post-Treatment Outcomes. BMC Women’s Health 2019, 19, 1–9. DOI: 10.1186/s12905-019-0748-8.
   PubMed Web of Science ®Google Scholar
• Pandit, A.; Kedar, A.; Koyate, K. Hollow Pessary Loaded with Lawsone via Self-Microemulsifying Drug Delivery System for Vaginal Candidiasis. J. Drug Deliv. Sci. Technol. 2020, 60, 101955. DOI: 10.1016/j.jddst.2020.101955.
   Web of Science ®Google Scholar
• Rahmoun, N.; Boucherit-Otmani, Z.; Boucherit, K.; Benabdallah, M.; Choukchou-Braham, N. Antifungal Activity of the Algerian Lawsonia inermis (Henna). Pharm. Biol. 2013, 51, 131–135. DOI: 10.3109/13880209.2012.715166.
   PubMed Web of Science ®Google Scholar
• Lu, M.; Xing, H.; Jiang, J.; Chen, X.; Yang, T.; Wang, D.; Ding, P. Liquisolid Technique and Its Applications in Pharmaceutics. Asian J. Pharm. Sci. 2017, 12, 115–123. DOI: 10.1016/j.ajps.2016.09.007.
   PubMed Web of Science ®Google Scholar
• Vraníková, B.; Gajdziok, J. Liquisolid Systems and Aspects Influencing Their Research and Development. Acta Pharm. 2013, 63, 447–465. DOI: 10.2478/acph-2013-0034.
   PubMed Web of Science ®Google Scholar
• Jadhav, N. R.; Irny, P. V.; Patil, U. S. Solid State Behavior of Progesterone and Its Release from Neusilin US2 Based Liquisolid Compacts. J. Drug Deliv. Sci. Technol. 2017, 38, 97–106. DOI: 10.1016/j.jddst.2017.01.009.
   Web of Science ®Google Scholar
• Spireas, S.; Bolton, S. M. Liquisolid System and Methods of Preparing Same. U.S. Patent 5,800,834, Sept 1, 1998.
   Google Scholar
• Jaydip, B.; Dhaval, M.; Soniwala, M. M.; Chavda, J. Formulation and Optimization of Liquisolid Compact for Enhancing Dissolution Properties of Efavirenz by Using DoE Approach. Saudi Pharm. J. 2020, 28, 737–745. DOI: 10.1016/j.jsps.2020.04.016.
   PubMed Web of Science ®Google Scholar
• Ali, B.; Khan, A.; Alyami, H. S.; Ullah, M.; Wahab, A.; Badshah, M.; Naz, A. Evaluation of the Effect of Carrier Material on Modification of Release Characteristics of Poor Water Soluble Drug from Liquisolid Compacts. PLoS One. 2021, 16, e0249075. DOI: 10.1371/journal.pone.0249075.
   PubMed Web of Science ®Google Scholar
• Jhaveri, M.; Nair, A. B.; Shah, J.; Jacob, S.; Patel, V.; Mehta, T. Improvement of Oral Bioavailability of Carvedilol by Liquisolid Compact: Optimization and Pharmacokinetic Study. Drug Deliv. Transl. Res. 2020, 10, 975–985. DOI: 10.1007/s13346-020-00734-3.
   PubMed Web of Science ®Google Scholar
• Devi, S.; Kumar, S.; Verma, V.; Kaushik, D.; Verma, R.; Bhatia, M. Enhancement of Ketoprofen Dissolution Rate by the Liquisolid Technique: Optimization and in Vitro and in Vivo Investigations. Drug Deliv. Transl. Res. 2022, 12, 2693–2707. DOI: 10.1007/s13346-022-01120-x.
   PubMed Web of Science ®Google Scholar
• El-Say, K. M.; Ahmed, T. A.; Ahmed, O. A.; Elimam, H. Enhancing the Hypolipidemic Effect of Simvastatin in Poloxamer-Induced Hyperlipidemic Rats via Liquisolid Approach: Pharmacokinetic and Pharmacodynamic Evaluation. AAPS PharmSciTech. 2020, 21, 223. DOI: 10.1208/s12249-020-01754-5.
   Google Scholar
• Naureen, F.; Shah, Y.; Shah, S. I.; Abbas, M.; Rehman, I. U.; Muhammad, S.; Hamdullah, H.; Goh, K. W.; Khuda, F.; Khan, A.; et al. Formulation Development of Mirtazapine Liquisolid Compacts: Optimization Using Central Composite Design. Molecules. 2022, 27, 4005. DOI: 10.3390/molecules27134005.
   PubMed Web of Science ®Google Scholar
• Saeedi, M.; Akbari, J.; Semnani, K.; Hashemi, S. M.; Ghasemi, S.; Tahmasbi, N.; Azizpoor, E.; Faghani, N.; Rostamkalaei, S. S.; Nokhodchi, A. Controlling Atorvastatin Release from Liquisolid Systems. J. Dispers. Sci. Technol. 2022, 43, 375–384. DOI: 10.1080/01932691.2020.1842211.
   Web of Science ®Google Scholar
• Hussain, Y.; Shah.; M. N.; Asim.ur.Rehman. Liquisolid Technique: A Novel Tool to Develop Aceclofenac-Loaded Eudragit L-100 and RS-100-Based Sustained Release Tablets. J. Pharm. Innov. 2020, 16, 659–671. DOI: 10.1007/s12247-020-09474-w.
   Web of Science ®Google Scholar
• Ward, A.; Walton, K.; Stoycheva, S.; Wallis, M.; Adebisi, A.; Nep, E.; Ngwuluka, N. C.; Shaboun, S.; Smith, A. M.; Conway, B. R.; Asare-Addo, K. The Use of Visible and UV Dissolution Imaging for the Assessment of Propranolol Hydrochloride in Liquisolid Compacts of Sesamum radiatum Gum. J. Drug Deliv. Sci. Technol. 2020, 56, 101511. DOI: 10.1016/j.jddst.2020.101511.
   Web of Science ®Google Scholar
• Jaipakdee, N.; Limpongsa, E.; Sripanidkulchai, B-o.; Piyachaturawat, P. Preparation of Curcuma comosa Tablets Using Liquisolid Techniques: In Vitro and in Vivo Evaluation. Int. J. Pharm. 2018, 553, 157–168. DOI: 10.1016/j.ijpharm.2018.10.031.
   PubMed Web of Science ®Google Scholar
• Rashad, A. A.; Nageeb El-Helaly, S.; Abd El Rehim, R. T.; El-Gazayerly, O. N. Chronological Delivery of Antihypertensive Drugs in Bilayered Core-in-Cup Buccoadhesive Tablets: In Vitro and in Vivo Evaluation. AAPS PharmSciTech. 2020, 21, 21–25. DOI: 10.1208/s12249-019-1575-9.
   Web of Science ®Google Scholar
• Cevher, E.; Açma, A.; Sinani, G.; Aksu, B.; Zloh, M.; Mülazımoğlu, L. Bioadhesive Tablets Containing Cyclodextrin Complex of Itraconazole for the Treatment of Vaginal Candidiasis. Int. J. Biol. Macromol. 2014, 69, 124–136. DOI: 10.1016/j.ijbiomac.2014.05.033.
   PubMed Web of Science ®Google Scholar
• Hassan, A. S.; Soliman, G. M.; Ali, M. F.; El-Mahdy, M. M.; El-Gindy, G. E. A. Mucoadhesive Tablets for the Vaginal Delivery of Progesterone: In Vitro Evaluation and Pharmacokinetics/Pharmacodynamics in Female Rabbits. Drug Dev. Ind. Pharm. 2018, 44, 224–232. DOI: 10.1080/03639045.2017.1386203.
   PubMed Web of Science ®Google Scholar
• Fitaihi, R. A.; Aleanizy, F. S.; Elsamaligy, S.; Mahmoud, H. A.; Bayomi, M. A. Role of Chitosan on Controlling the Characteristics and Antifungal Activity of Bioadhesive Fluconazole Vaginal Tablets. Saudi Pharm. J. 2018, 26, 151–161. DOI: 10.1016/j.jsps.2017.12.016.
   PubMed Web of Science ®Google Scholar
• Bonthagarala, B.; Dasari, V.; Kotra, V.; Swain, S.; Beg, S. Quality-by-Design Based Development and Characterization of Pioglitazone Loaded Liquisolid Compact Tablets with Improved Biopharmaceutical Attributes. J. Drug Deliv. Sci. Technol. 2019, 51, 345–355. DOI: 10.1016/j.jddst.2019.03.033.
   Web of Science ®Google Scholar
• Argade, P.; Patole, V. C.; Pandit, A. P. Liquisolid Compact Tablet of Candesartan Cilexetil with Enhanced Solubility Using Neusilin US2, Aerosil 200 and Transcutol HP. Indian J. Pharm. Educ. Res. 2019, 53, 457–467. DOI: 10.5530/ijper.53.3.78.
   Web of Science ®Google Scholar
• Tietz, K.; Klein, S. Simulated Genital Tract Fluids and Their Applicability in Drug Release/Dissolution Testing of Vaginal Dosage Forms. Dissolution Technol. 2018, 25, 40–51. DOI: 10.14227/DT250318P40.
   Web of Science ®Google Scholar
• Abd, N. H.; Abdel-Aleem, J. A.; Abdo, M. N.; Abou-Ghadir, O. F.; Zahran, K. M.; Hetta, H. F. Efficacy of Ketoconazole Gel-Flakes in Treatment of Vaginal Candidiasis: Formulation, In Vitro and Clinical Evaluation. Int. J. Pharm. 2019, 567, 118472. DOI: 10.1016/j.ijpharm.2019.118472.
   PubMed Web of Science ®Google Scholar
• Singh, R. M.; Kumar, A.; Pathak, K. Thermally Triggered Mucoadhesive In Situ Gel of Loratadine: β-Cyclodextrin Complex for Nasal Delivery. AAPS PharmSciTech. 2013, 14, 412–424. DOI: 10.1208/s12249-013-9921-9.
   PubMed Web of Science ®Google Scholar
• Palmeira-de-Oliveira, R.; Machado, R. M.; Martinez-de-Oliveira, J.; Palmeira-de-Oliveira, A. Testing Vaginal Irritation with the Hen’s Egg Test-Chorioallantoic Membrane Assay. ALTEX-Altern Anim Exp. 2018, 35, 495–503. DOI: 10.14573/altex.1710091.
   PubMed Web of Science ®Google Scholar
• Alonzo, D. E.; Zhang, G. G.; Zhou, D.; Gao, Y.; Taylor, L. S. Understanding the Behavior of Amorphous Pharmaceutical Systems during Dissolution. Pharm. Res. 2010, 27, 608–618. DOI: 10.1007/s11095-009-0021-1.
   PubMed Web of Science ®Google Scholar
• Chella, N.; Shastri, N.; Tadikonda, R. R. Use of the Liquisolid Compact Technique for Improvement of the Dissolution Rate of Valsartan. Acta Pharm Sin B 2012, 2, 502–508. DOI: 10.1016/j.apsb.2012.07.005.
   Google Scholar
• Burra, S.; Yamsani, M.; Vobalaboina, V. The Liquisolid Technique: An Overview. Braz. J. Pharm. Sci. 2011, 47, 475–482. DOI: 10.1590/S1984-82502011000300005.
   Web of Science ®Google Scholar
• Fahmy, R. H.; Kassem, M. A. Enhancement of Famotidine Dissolution Rate through Liquisolid Tablets Formulation: In Vitro and in Vivo Evaluation. Eur. J. Pharm. Biopharm. 2008, 69, 993–1003. DOI: 10.1016/j.ejpb.2008.02.017.
   PubMed Web of Science ®Google Scholar
• Agarwal, S.; Murthy, R. S. Effect of Different Polymer Concentration on Drug Release Rate and Physicochemical Properties of Mucoadhesive Gastroretentive Tablets. Indian J. Pharm. Sci. 2015, 77, 705–714. DOI: 10.4103/2F0250-474x.174993.
   PubMed Web of Science ®Google Scholar
• Arpa, M. D.; Yoltaş, A.; Onay Tarlan, E.; Şenyüz, C. Ş.; Sipahi, H.; Aydın, A.; Üstündağ Okur, N. New Therapeutic System Based on Hydrogels for Vaginal Candidiasis Management: Formulation–Characterization and In Vitro Evaluation Based on Vaginal Irritation and Direct Contact Test. Pharm. Dev. Technol. 2020, 25, 1238–1248. DOI: 10.1080/10837450.2020.1809457.
   PubMed Web of Science ®Google Scholar
• Hani, U.; Krishna, G.; Shivakumar, H. G. Design and Optimization of Clotrimazole–Hydroxypropyl-β-Cyclodextrin Bioadhesive Vaginal Tablets Using Anacardium occidentale Gum by 32 Factorial Design. RSC Adv. 2015, 5, 35391–35404. DOI: 10.1039/C5RA04305K.
   Web of Science ®Google Scholar
• https://www.accessdata.fda.gov/drugsatfda_docs/label/1998/20574lbl.pdf (accessed on Aug 27, 2022).
   Google Scholar