Salivary and plasma cortisol and testosterone responses to interval and tempo runs and a bodyweight-only circuit session in endurance-trained men

References

• Aardal, E., & Holm, A. C. (1995). Cortisol in saliva – reference ranges and relation to cortisol in serum. European Journal of Clinical Chemistry and Clinical Biochemistry, 33(12), 927–932.
   PubMedGoogle Scholar
• Ahtiainen, J. P., Pakarinen, A., Kraemer, W. J., & Hakkinen, K. (2004). Acute hormonal responses to heavy resistance exercise in strength athletes versus nonathletes. Canadian Journal of Applied Physiology, 29(5), 527–543.
   PubMedGoogle Scholar
• Allgrove, J. E., Gomes, E., Hough, J., & Gleeson, M. (2008). Effects of exercise intensity on salivary antimicrobial proteins and markers of stress in active men. Journal of Sports Sciences, 26(6), 653–661.
   PubMed Web of Science ®Google Scholar
• Beaven, C. M., Gill, N. D., & Cook, C. J. (2008). Salivary testosterone and cortisol responses in professional rugby players after four resistance exercise protocols. Journal of Strength and Conditioning Research, 22(2), 426–432. doi: 410.1519/JSC.1510b1013e3181635843
   PubMed Web of Science ®Google Scholar
• Bhasin, S., Storer, T. W., Berman, N., Callegari, C., Clevenger, B., Phillips, J., … Casaburi, R. (1996). The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men. The New England Journal of Medicine, 335(1), 1–7. doi: 10.1056/NEJM199607043350101
   PubMed Web of Science ®Google Scholar
• Borg, G. A. (1982). Psychophysical bases of perceived exertion. Medicine and Science in Sports and Exercise, 14(5), 377–381.
   PubMed Web of Science ®Google Scholar
• Budde, H., Voelcker-Rehage, C., Pietrassyk-Kendziorra, S., Machado, S., Ribeiro, P., & Arafat, A. M. (2010). Steroid hormones in the saliva of adolescents after different exercise intensities and their influence on working memory in a school setting. Psychoneuroendocrinology, 35(3), 382–391.
   PubMed Web of Science ®Google Scholar
• Cadore, E., Lhullier, F., Brentano, M., Silva, E., Ambrosini, M., Spinelli, R., … Kruel, L. (2008). Correlations between serum and salivary hormonal concentrations in response to resistance exercise. Journal of Sports Sciences, 26(10), 1067–1072.
   PubMed Web of Science ®Google Scholar
• Cadore, E. L., Lhullier, F. L., Alberton, C. L., Almeida, A. P., Sapata, K. B., Korzenowski, A. L., & Kruel, L. F. (2009). Salivary hormonal responses to different water-based exercise protocols in young and elderly men. Journal of Strength and Conditioning Research, 23(9), 2695–2701.
   PubMed Web of Science ®Google Scholar
• Cadoux-Hudson, T. A., Few, J. D., & Imms, F. J. (1985). The effect of exercise on the production and clearance of testosterone in well trained young men. European Journal of Applied Physiology and Occupational Physiology, 54(3), 321–325. doi: 10.1007/bf00426153
   PubMed Web of Science ®Google Scholar
• Chicharro, J. L., Lucia, A., Perez, M., Vaquero, A. F., & Urena, R. (1998). Saliva composition and exercise. Sports Medicine, 26(1), 17–27.
   PubMed Web of Science ®Google Scholar
• Chrousos, G. P. (1998). Stressors, stress, and neuroendocrine integration of the adaptive response: The 1997 Hans Selye memorial lecture. Annals of the New York Academy of Sciences, 851(1), 311–335.
   PubMed Web of Science ®Google Scholar
• Cook, C. J., & Beaven, C. M. (2013). Salivary testosterone is related to self-selected training load in elite female athletes. Physiology & Behavior, 116–117, 8–12. doi: 10.1016/j.physbeh.2013.03.013
   PubMed Web of Science ®Google Scholar
• Cook, C. J., & Crewther, B. T. (2012). Changes in salivary testosterone concentrations and subsequent voluntary squat performance following the presentation of short video clips. Hormones and Behavior, 61(1), 17–22. doi: 10.1016/j.yhbeh.2011.09.006
   PubMed Web of Science ®Google Scholar
• Crewther, B., Cronin, J., Keogh, J., & Cook, C. (2008). The salivary testosterone and cortisol response to three loading schemes. Journal of Strength and Conditioning Research, 22(1), 250–255.
   PubMed Web of Science ®Google Scholar
• Crewther, B., Keogh, J., Cronin, J., & Cook, C. (2006). Possible stimuli for strength and power adaptation: Acute hormonal responses. Sports Medicine, 36(3), 215–238.
   PubMed Web of Science ®Google Scholar
• Crewther, B., Lowe, T., Ingram, J., & Weatherby, R. (2010). Validating the salivary testosterone and cortisol concentration measures in response to short high-intensity exercise. Journal of Sports Medicine and Physical Fitness, 50(1), 85–92.
   PubMed Web of Science ®Google Scholar
• Crewther, B. T., Cook, C., Cardinale, M., Weatherby, R. P., & Lowe, T. (2011). Two emerging concepts for elite athletes: The short-term effects of testosterone and cortisol on the neuromuscular system and the dose-response training role of these endogenous hormones. Sports Medicine, 41(2), 103–123. doi: 10.2165/11539170-000000000-00000
   PubMed Web of Science ®Google Scholar
• Dimitriou, L., Sharp, N. C., & Doherty, M. (2002). Circadian effects on the acute responses of salivary cortisol and IgA in well trained swimmers. British Journal of Sports Medicine, 36(4), 260–264.
   PubMed Web of Science ®Google Scholar
• Eliakim, A., Portal, S., Zadik, Z., Rabinowitz, J., Adler-Portal, D., Cooper, D. M., … Nemet, D. (2009). The effect of a volleyball practice on anabolic hormones and inflammatory markers in elite male and female adolescent players. Journal of Strength and Conditioning Research, 23(5), 1553–1559.
   PubMed Web of Science ®Google Scholar
• Elloumi, M., Maso, F., Michaux, O., Robert, A., & Lac, G. (2003). Behaviour of saliva cortisol [C], testosterone [T] and the T/C ratio during a rugby match and during the post-competition recovery days. European Journal of Applied Physiology, 90(1–2), 23–28.
   PubMed Web of Science ®Google Scholar
• Fahrner, C. L., & Hackney, A. C. (1998). Effects of endurance exercise on free testosterone concentration and the binding affinity of sex hormone binding globulin (SHBG). International Journal of Sports Medicine, 19(1), 12–15.
   Google Scholar
• Farrell, P. A., Garthwaite, T. L., & Gustafson, A. B. (1983). Plasma adrenocorticotropin and cortisol responses to submaximal and exhaustive exercise. Journal of Applied Physiology, 55(5), 1441–1444.
   PubMed Web of Science ®Google Scholar
• Fry, A., & Lohnes, C. (2010). Acute testosterone and cortisol responses to high power resistance exercise. Human Physiology, 36(4), 457–461. doi: 10.1134/s0362119710040110
   Google Scholar
• Gozansky, W. S., Lynn, J. S., Laudenslage, M. L., & Kohurt, W. M. (2005). Salivary cortisol determined by enzyme immunoassay is preferable to serum total cortisol for assessment of dynamic hypothamlamic-pituitary-adrenal axis activity. Clinical Endocrinology, 63(3), 336–341.
   PubMed Web of Science ®Google Scholar
• Granger, D. A., Schwartz, E. B., Booth, A., & Arentz, M. (1999). Salivary testosterone determination in studies of child health and development. Hormones and Behavior, 35(1), 18–27. doi: http://dx.doi.org/10.1006/hbeh.1998.1492
   PubMed Web of Science ®Google Scholar
• Hakkinen, K., & Pakarinen, A. (1993). Acute hormonal responses to two different fatiguing heavy-resistance protocols in male athletes. Journal of Applied Physiology, 74(2), 882–887.
   PubMed Web of Science ®Google Scholar
• Hickson, R. C., Hidaka, K., Foster, C., Falduto, M. T., & Chatterton, R. T. (1994). Successive time courses of strength development and steroid hormone responses to heavy-resistance training. Journal of Applied Physiology, 76(2), 663–670.
   PubMed Web of Science ®Google Scholar
• Hough, J. P., Papacosta, E., Wraith, E., & Gleeson, M. (2011). Plasma and salivary steroid hormone responses of men to high-intensity cycling and resistance exercise. Journal of Strength and Conditioning Research, 25(1), 23–31.
   PubMed Web of Science ®Google Scholar
• Humphrey, S. P., & Williamson, R. T. (2001). A review of saliva: Normal composition, flow, and function. Journal of Prosthetic Dentistry, 85(2), 162–169.
   PubMed Web of Science ®Google Scholar
• Jacks, D. E., Sowash, J., Anning, J., McGloughlin, T., & Andres, F. (2002). Effect of exercise at three exercise intensities on salivary cortisol. Journal of Strength and Conditioning Research, 16(2), 286–289.
   PubMed Web of Science ®Google Scholar
• Jessop, D. S. (1999). Stimulatory and inhibitory regulators of the hypothalamo–pituitary–adrenocortical axis. Best Practice & Research Clinical Endocrinology & Metabolism, 13(4), 491–501. doi: http://dx.doi.org/10.1053/beem.1999.0039
   Web of Science ®Google Scholar
• Jezova, D., & Vigas, M. (1981). Testosterone response to exercise during blockade and stimulation of adrenergic receptors in man. Hormone Research, 15(3), 141–147.
   PubMed Web of Science ®Google Scholar
• Kirschbaum, C., & Hellhammer, D. H. (1989). Salivary cortisol in psychobiological research: An overview. Neuropsychbiology, 22(3), 150–169.
   PubMed Web of Science ®Google Scholar
• Kirschbaum, C., & Hellhammer, D. H. (1994). Salivary cortisol in psychoendocrine research: Recent developements and applications. Psychoneuroendocrinology, 19, 313–333.
   PubMed Web of Science ®Google Scholar
• Kirschbaum, C., & Hellhammer, D. H. (2000). Salivary cortisol. In G. Fink (Ed.), Encyclopedia of stress (Vol. 3, pp. 379–383). San Diego, CA: Academic Press.
   Google Scholar
• Kokalas, N., Tsalis, G., Tsigilis, N., & Mougios, V. (2004). Hormonal responses to three training protocols in rowing. European Journal of Applied Physiology, 92(1–2), 128–132.
   PubMed Web of Science ®Google Scholar
• Komesaroff, P. A., & Funder, J. W. (1994). Differential glucocorticoid effects on catecholamine responses to stress. American Journal of Physiology – Endocrinology And Metabolism, 266(1), E118–E128.
   Google Scholar
• Kraemer, W. J., Fleck, S. J., Dziados, J. E., Harman, E. A., Marchitelli, L. J., Gordon, S. E., … Triplett, N. T. (1993). Changes in hormonal concentrations after different heavy-resistance exercise protocols in women. Journal of Applied Physiology, 75(2), 594–604.
   PubMed Web of Science ®Google Scholar
• Kraemer, W. J., Fleck, S. J., Maresh, C. M., Ratamess, N. A., Gordon, S. E., Goetz, K. L., … Patton, J. F. (1999). Acute hormonal responses to a single bout of heavy resistance exercise in trained power lifters and untrained men. Canadian Journal of Applied Physiology, 24(6), 524–537.
   PubMedGoogle Scholar
• Kraemer, W. J., Gordon, S. E., Fleck, S. J., Marchitelli, L. J., Mello, R., Dziados, J. E., … Fry, A. C. (1991). Endogenous anabolic hormonal and growth factor responses to heavy resistance exercise in males and females. International Journal of Sports Medicine, 12(2), 228–235.
   PubMed Web of Science ®Google Scholar
• Kraemer, W. J., Marchitelli, L., Gordon, S. E., Harman, E., Dziados, J. E., Mello, R., … Fleck, S. J. (1990). Hormonal and growth factor responses to heavy resistance exercise protocols. Journal of Applied Physiology, 69(4), 1442–1450.
   PubMed Web of Science ®Google Scholar
• Lin, H., Wang, S. W., Wang, R. Y., & Wang, P. S. (2001). Stimulatory effect of lactate on testosterone production by rat Leydig cells. Journal of Cellular Biochemistry, 83(1), 147–154.
   PubMed Web of Science ®Google Scholar
• Linnamo, V., Pakarinen, A., Komi, P. V., Kraemer, W. J., & Hakkinen, K. (2005). Acute hormonal responses to submaximal and maximal heavy resistance and explosive exercises in men and women. Journal of Strength and Conditioning Research, 19(3), 566–571.
   PubMed Web of Science ®Google Scholar
• Lu, S. S., Lau, C. P., Tung, Y. F., Huang, S. W., Chen, Y. H., Shih, H. C., … Wang, P. S. (1997). Lactate and the effects of exercise on testosterone secretion: Evidence for the involvement of a cAMP-mediated mechanism. Medicine & Science in Sports & Exercise, 29(8), 1048–1054.
   PubMed Web of Science ®Google Scholar
• McCaulley, G. O., McBride, J. M., Cormie, P., Hudson, M. B., Nuzzo, J. L., Quindry, J. C., & Travis Triplett, N. (2009). Acute hormonal and neuromuscular responses to hypertrophy, strength and power type resistance exercise. European Journal of Applied Physiology, 105(5), 695–704.
   PubMed Web of Science ®Google Scholar
• Moreira, A., Arsati, F., de Oliveira Lima Arsati, Y. B., da Silva, D. A., & de Araujo, V. C. (2009). Salivary cortisol in top-level professional soccer players. European Journal of Applied Physiology, 106(1), 25–30.
   PubMed Web of Science ®Google Scholar
• Morgan, R. E., & Adamson, G. T. (1965). Circuit training. London: G. Bell.
   Google Scholar
• Obmiński, Z. (1998). Changes in the free (unbound) fraction of testosterone in serum in vitro as affected by pH and temperature. Experimental and Clinical Endocrinology and Diabetes, 106(01), 85–88. doi: 10.1055/s-0029-1211956
   PubMed Web of Science ®Google Scholar
• Obminski, Z., & Stupnicki, R. (1996). Effect of temperature and pH on the magnitude of the free fraction of cortisol in serum. Experimental and Clinical Endocrinology and Diabetes, 104(4), 350–352.
   PubMed Web of Science ®Google Scholar
• Obmiński, Z., & Stupnicki, R. (1997). Comparison of the testosterone-to-cortisol ratio values obtained from hormonal assays in saliva and serum. Journal of Sports Medicine and Physical Fitness, 37(1), 50–55.
   PubMed Web of Science ®Google Scholar
• O’Connor, P. J., & Corrigan, D. L. (1987). Influence of short-term cycling on salivary cortisol levels. Medicine & Science in Sports & Exercise, 19(3), 224–228.
   PubMed Web of Science ®Google Scholar
• Port, K. (1991). Serum and saliva cortisol responses and blood lactate accumulation during incremental exercise testing. International Journal of Sports Medicine, 12(05), 490–494. doi: 10.1055/s-2007-1024720
   PubMed Web of Science ®Google Scholar
• Raastad, T., Bjoro, T., & Hallen, J. (2000). Hormonal responses to high- and moderate-intensity strength exercise. European Journal of Applied Physiology, 82(1–2), 121–128.
   PubMed Web of Science ®Google Scholar
• Rose, R. M., Kreuz, L. E., Holaday, J. W., Sulak, K. J., & Johnson, C. E. (1972). Diurnal variation of plasma testosterone and cortisol. Journal of Endocrinology, 54(1), 177–178. doi: 10.1677/joe.0.0540177
   PubMed Web of Science ®Google Scholar
• Rosner, W. (1990). The functions of corticosteroid-binding globulin and sex hormone-binding globulin: Recent advances. Endocrine Reviews, 11(1), 80–91. doi: 10.1210/edrv-11-1-80
   PubMed Web of Science ®Google Scholar
• Rowell, L. B., Blackmon, J. R., & Bruce, R. A. (1964). Indocyanine green clearance and estimated hepatic blood flow during mild to maximal exercise in upright man. Journal of Clinical Investigation, 43, 1677–1690.
   PubMed Web of Science ®Google Scholar
• Rudolph, D. L., & McAuley, E. (1998). Cortisol and affective responses to exercise. Journal of Sports Sciences, 16(2), 121–128.
   PubMed Web of Science ®Google Scholar
• Salway, J. G. (2006). Medical biochemistry at a glance (2nd ed.). Oxford: Blackwell.
   Google Scholar
• Smilios, I., Pilianidis, T., Karamouzis, M., & Tokmakidis, S. P. (2003). Hormonal responses after various resistance exercise protocols. Medicine & Science in Sports & Exercise, 35(4), 644–654.
   PubMed Web of Science ®Google Scholar
• Sutton, J. R., Coleman, M. J., Casey, J., & Lazarus, L. (1973). Androgen responses during physical exercise. British Medical Journal (Clinical Research Ed.), 1(5852), 520–522. doi: 10.1136/bmj.1.5852.520
   PubMed Web of Science ®Google Scholar
• Taipale, R., Mikkola, J., Nummela, A., Vesterinen, V., Capostagno, B., Walker, S., … Häkkinen, K. (2010). Strength training in endurance runners. International Journal of Sports Medicine, 31(7), 468–476.
   PubMed Web of Science ®Google Scholar
• Tremblay, M. S., Copeland, J. L., & Van Helder, W. (2004). Effect of training status and exercise mode on endogenous steroid hormones in men. Journal of Applied Physiology, 96(2), 531–539. doi: 10.1152/japplphysiol.00656.2003
   PubMed Web of Science ®Google Scholar
• Tuck, M. K., Chan, D. W., Chia, D., Godwin, A. K., Grizzle, W. E., Krueger, K. E., … Brenner, D. E. (2008). Standard operating procedures for serum and plasma collection: Early detection research network consensus statement standard operating procedure integration working group. Journal of Proteome Research, 8(1), 113–117.
   Web of Science ®Google Scholar
• VanBruggen, M. D., Hackney, A. C., McMurray, R. G., & Ondrak, K. S. (2011). The relationship between serum and salivary cortisol levels in response to different intensities of exercise. International Journal of Sports Physiology Performance, 6(3), 396–407.
   PubMed Web of Science ®Google Scholar
• Viru, A., & Viru, M. (2005). Preconditioning of the performance in power events by endogenous testosterone: In memory of professor Carmelo Bosco. Journal of Strength and Conditioning Research, 19(1), 6–8. doi: 10.1519/1533-4287(2005)19<6:POTPIP>2.0.CO;2
   PubMed Web of Science ®Google Scholar
• Vittek, J., L’Homedeiu, D., Gordon, G., Rappaport, S., & Southren, A. (1985). Direct radioimmunoassay (RIA) of salivary testosterone correlation with free and total serum testosterone. Life Sciences, 37, 711–716.
   PubMed Web of Science ®Google Scholar
• Vuorimaa, T., Ahotupa, M., Hakkinen, K., & Vasankari, T. (2008). Different hormonal response to continuous and intermittent exercise in middle-distance and marathon runners. Scandinavian Journal of Medicine and Science in Sports, 18(5), 565–572.
   PubMed Web of Science ®Google Scholar
• Wang, C., Plymate, S., Nieschlag, E., & Paulsen, C. (1981). Salivary testosterone in men: Further evidence of a direct correlation with free serum testosterone. Journal of Clinical Endocrinology and Metabolism, 53(5), 1021–1024.
   PubMed Web of Science ®Google Scholar
• West, D. W., Burd, N. A., Tang, J. E., Moore, D. R., Staples, A. W., Holwerda, A. M., … Phillips, S. M. (2010). Elevations in ostensibly anabolic hormones with resistance exercise enhance neither training-induced muscle hypertrophy nor strength of the elbow flexors. Journal of Applied Physiology, 108(1), 60–67. doi: 10.1152/japplphysiol.01147.2009
   PubMed Web of Science ®Google Scholar
• West, D. W., & Phillips, S. M. (2012). Associations of exercise-induced hormone profiles and gains in strength and hypertrophy in a large cohort after weight training. European Journal of Applied Physiology, 112(7), 2693–2702. doi: 10.1007/s00421-011-2246-z
   PubMed Web of Science ®Google Scholar
• Wilkinson, S. B., Tarnopolsky, M. A., Grant, E. J., Correia, C. E., & Phillips, S. M. (2006). Hypertrophy with unilateral resistance exercise occurs without increases in endogenous anabolic hormone concentration. European Journal of Applied Physiology, 98(6), 546–555. doi: 10.1007/s00421-006-0300-z
   PubMed Web of Science ®Google Scholar
• Yoshida, T., Chida, M., Ichioka, M., & Suda, Y. (1987). Blood lactate parameters related to aerobic capacity and endurance performance. European Journal of Applied Physiology and Occupational Physiology, 1(56), 7–11.
   Google Scholar