209
Views
0
CrossRef citations to date
0
Altmetric
Physical Activity, Health and Exercise

The effect of metformin treatment on volumes of free-living physical activity and sedentary behaviour: A post-hoc analysis of the PRE-D trial

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon show all
Pages 1687-1691 | Received 13 Jun 2022, Accepted 28 Nov 2023, Published online: 05 Dec 2023

References

  • American Diabetes Association. (2021). 9. Pharmacologic approaches to glycemic treatment. Diabetes Care, 40(Supplement 1), S64–S74. https://doi.org/10.2337/dc17-S011
  • Assah, F. K., Brage, S., Ekelund, U., Wareham, N. J. (2008). The association of intensity and overall level of physical activity energy expenditure with a marker of insulin resistance. Diabetologia, 51(8), 1399–1407. https://doi.org/10.1007/s00125-008-1033-9
  • Clemmensen, K. K. B., Blond, M. B., Amadid, H., Bruhn, L., Vistisen, D., Karstoft, K., Persson, F., Ried-Larsen, M., Holst, J. J., Albrechtsen, N. J. W., Torekov, S. S., Quist, J. S., Jorgensen, M. E., & Færch, K. (2021). No effects of dapagliflozin, metformin or exercise on plasma glucagon concentrations in individuals with prediabetes: A post hoc analysis from the randomized controlled PRE‐D trial. Diabetes, Obesity & Metabolism, 23(2), 530–539. https://doi.org/10.1111/dom.14246
  • Das, S., Behera, S. K., Srinivasan, A., Xavier, A. S., Selvarajan, S., Kamalanathan, S., Sahoo, J. P., & Nair, N. S. (2018). Effect of metformin on exercise capacity: A meta-analysis. Diabetes Research and Clinical Practice, 144, 270–278. https://doi.org/10.1016/j.diabres.2018.08.022
  • Færch, K., Amadid, H., Nielsen, L. B., Ried-Larsen, M., Karstoft, K., Persson, F., & Jørgensen, M. E. (2017). Protocol for a randomised controlled trial of the effect of dapagliflozin, metformin and exercise on glycaemic variability, body composition and cardiovascular risk in prediabetes (the PRE-D trial). British Medical Journal Open, 7(5), e013802. https://doi.org/10.1136/bmjopen-2016-013802
  • Færch, K., Blond, M. B., Bruhn, L., Amadid, H., Vistisen, D., Clemmensen, K. K. B., Vainø, C. T. R., Pedersen, C., Tvermosegaard, M., Dejgaard, T. F., Karstoft, K., Ried-Larsen, M., Persson, F., & Jørgensen, M. E. (2021). The effects of dapagliflozin, metformin or exercise on glycaemic variability in overweight or obese individuals with prediabetes (the PRE-D trial): A multi-arm, randomised, controlled trial. Diabetologia, 64(1), 42–55. https://doi.org/10.1007/s00125-020-05306-1
  • Falconer, C. L., Page, A. S., Andrews, R. C., & Cooper, A. R. (2015). The potential impact of displacing sedentary time in adults with type 2 diabetes. Medicine & Science in Sports & Exercise, 47(10), 2070–2075. https://doi.org/10.1249/MSS.0000000000000651
  • Healy, G. N., Dunstan, D. W., Salmon, J., Cerin, E., Shaw, J. E., Zimmet, P. Z., & Owen, N. (2008). Breaks in sedentary time: Beneficial associations with metabolic risk. Diabetes Care, 31(4), 661–666. https://doi.org/10.2337/dc07-2046
  • Kristensen, J. M., Lillelund, C., Kjøbsted, R., Birk, J. B., Andersen, N. R., Nybo, L., Mellberg, K., Balendran, A., Richter, E. A., & Wojtaszewski, J. F. P. (2019). Metformin does not compromise energy status in human skeletal muscle at rest or during acute exercise: A randomised, crossover trial. Physiological Reports, 7(23). https://doi.org/10.14814/phy2.14307
  • Manson, J. E., Greenland, P., LaCroix, A. Z., Stefanick, M. L., Mouton, C. P., Oberman, A., Perri, M. G., Sheps, D. S., Pettinger, M. B., & Siscovick, D. S. (2002). Walking compared with vigorous exercise for the prevention of cardiovascular events in women. The New England Journal of Medicine, 347(10), 716–725. https://doi.org/10.1056/NEJMoa021067
  • Perri, M. G., Anton, S. D., Durning, P. E., Ketterson, T. U., Sydeman, S. J., Berlant, N. E., Kanasky, W. F., Newton, R. L., Limacher, M. C., & Martin, A. D. (2002). Adherence to exercise prescriptions: Effects of prescribing moderate versus higher levels of intensity and frequency. Health Psychology, 21(5), 452–458. https://doi.org/10.1037/0278-6133.21.5.452
  • Pilmark, N. S., Lyngbæk, M., Oberholzer, L., Elkjær, I., Petersen-Bønding, C., Kofoed, K., Siebenmann, C., Kellenberger, K., van Hall, G., Abildgaard, J., Ellingsgaard, H., Lauridsen, C., Ried-Larsen, M., Pedersen, B. K., Hansen, K. B., & Karstoft, K. (2021). The interaction between metformin and physical activity on postprandial glucose and glucose kinetics: A randomised, clinical trial. Diabetologia, 64(2), 397–409. https://doi.org/10.1007/s00125-020-05282-6
  • Pilmark, N. S., Petersen-Bønding, C., Holm, N. F. R., Johansen, M. Y., Pedersen, B. K., Hansen, K. B., & Karstoft, K. (2021). The effect of metformin on self-selected exercise intensity in healthy, lean males: A randomized, crossover, counterbalanced trial. Frontiers in Endocrinology, 12, 599164. https://doi.org/10.3389/fendo.2021.599164
  • Plotnikoff, R. C., Taylor, L. M., Wilson, P. M., COURNEYA, K. S., SIGAL, R. J., BIRKETT, N., RAINE, K., & SVENSON, L. W. (2006). Factors associated with physical activity in Canadian adults with Diabetes. Medicine & Science in Sports & Exercise, 38(8), 1526–1534. https://doi.org/10.1249/01.mss.0000228937.86539.95
  • Unick, J. L., Gaussoin, S. A., Hill, J. O., JAKICIC, J. M., BOND, D. S., HELLGREN, M., JOHNSON, K. C., PETERS, A. L., CODAY, M., KITZMAN, D. W., BOSSART, S., & WING, R. R. (2016). Four-year physical activity levels among intervention participants with type 2 Diabetes. Medicine & Science in Sports & Exercise, 48(12), 2437–2445. https://doi.org/10.1249/MSS.0000000000001054

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.