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Articles

Can neuroimaging help aphasia researchers? Addressing generalizability, variability, and interpretability

, &
Pages 377-393 | Received 08 Mar 2017, Accepted 01 Nov 2017, Published online: 30 Nov 2017

References

  • Amunts, K., Schleicher, A., Bürgel, U., Mohlberg, H., Uylings, H., & Zilles, K. (1999). Broca’s region revisited: Cytoarchitecture and intersubject variability. Journal of Comparative Neurology, 412(2), 319–341. <319::AID-CNE10>3.0.CO;2-7 doi: 10.1002/(SICI)1096-9861(19990920)412:2<319::AID-CNE10>3.0.CO;2-7
  • Anglade, C., Thiel, A., & Ansaldo, A. I. (2014). The complementary role of the cerebral hemispheres in recovery from aphasia after stroke: A critical review of literature. Brain Injury, 28(2), 138–145. doi: 10.3109/02699052.2013.859734
  • Assem, M., Blank, I. A., Mineroff, Z., Ademoglu, A., & Fedorenko, E. (2017). Multiple demand system’s activity predicts individual differences in working memory and fluid intelligence.
  • Axelrod, V., Bar, M., Rees, G., & Yovel, G. (2015). Neural correlates of subliminal language processing. Cerebral Cortex, 25(8), 2160–2169. doi: 10.1093/cercor/bhu022
  • Badecker, W., & Caramazza, A. (1985). On considerations of method and theory governing the use of clinical categories in neurolinguistics and cognitive neuropsychology: The case against agrammatism. Cognition, 20(2), 97–125. doi: 10.1016/0010-0277(85)90049-6
  • Baker, J. M., Rorden, C., & Fridriksson, J. (2010). Using transcranial direct-current stimulation to treat stroke patients with aphasia. Stroke, 41(6), 1229–1236. doi: 10.1161/STROKEAHA.109.576785
  • Bakheit, A., Shaw, S., Barrett, L., Wood, J., Carrington, S., Griffiths, S., … Koutsi, F. (2007). A prospective, randomized, parallel group, controlled study of the effect of intensity of speech and language therapy on early recovery from poststroke aphasia. Clinical Rehabilitation, 21(10), 885–894. doi: 10.1177/0269215507078486
  • Basilakos, A., Smith, K. G., Fillmore, P., Fridriksson, J., & Fedorenko, E. (2017). Functional characterization of the human speech articulation network. Cerebral Cortex, 1–15. doi: 10.1093/cercor/bhx100
  • Basso, A., Bracchi, M., Capitani, E., & Laiacona, M. (1987). Age and evolution of language area functions: A study of adult stroke patients. Cortex, 23, 475–483. doi: 10.1016/S0010-9452(87)80008-4
  • Bates, E., Appelbaum, M., & Allard, L. (1991). Statistical constraints on the use of single cases in neuropsychological research. Brain and Language, 40(3), 295–329. doi: 10.1016/0093-934X(91)90132-K
  • Bates, E., McDonald, J., MacWhinney, B., & Appelbaum, M. (1991). A maximum likelihood procedure for the analysis of group and individual data in aphasia research. Brain and Language, 40(2), 231–265. doi: 10.1016/0093-934X(91)90126-L
  • Bates, E., Wilson, S. M., Saygin, A. P., Dick, F., Sereno, M. I., Knight, R. T., & Dronkers, N. F. (2003). Voxel-based lesion–symptom mapping. Nature Neuroscience, 6(5), 448–450. https://doi.org/10.1101/110270 doi: 10.1038/nn1050
  • Ben-Shachar, M., Hendler, T., Kahn, I., Ben-Bashat, D., & Grodzinsky, Y. (2003). The neural reality of syntactic transformations evidence from functional magnetic resonance imaging. Psychological Science, 14(5), 433–440. doi: 10.1111/1467-9280.01459
  • Ben-Shachar, M., Palti, D., & Grodzinsky, Y. (2004). Neural correlates of syntactic movement: Converging evidence from two fMRI experiments. NeuroImage, 21(4), 1320–1336. doi: 10.1016/j.neuroimage.2003.11.027
  • Berthier, M. L. (2005). Poststroke aphasia: Epidemiology, pathophysiology and treatment. Drugs & Aging, 22(2), 163–182. doi: 10.2165/00002512-200522020-00006
  • Bi, Y., Han, Z., Shu, H., & Caramazza, A. (2007). Nouns, verbs, objects, actions, and the animate/inanimate effect. Cognitive Neuropsychology, 24(5), 485–504. doi: 10.1080/02643290701502391
  • Binder, J. R., Frost, J. A., Hammeke, T. A., Cox, R. W., Rao, S. M., & Prieto, T. (1997). Human brain language areas identified by functional magnetic resonance imaging. The Journal of Neuroscience, 17(1), 353–362.
  • Blank, I. A., Balewski, Z., Mahowald, K., & Fedorenko, E. (2016). Syntactic processing is distributed across the language system. Neuroimage, 127, 307–323. doi: 10.1016/j.neuroimage.2015.11.069
  • Blank, I. A., Kanwisher, N., & Fedorenko, E. (2014). A functional dissociation between language and multiple-demand systems revealed in patterns of BOLD signal fluctuations. Journal of Neurophysiology, 112(5), 1105–1118. doi: 10.1152/jn.00884.2013
  • Blank, I. A., Rohter, S. V., Kiran, S., & Fedorenko, E. (2015). Functional reorganization of the large-scale brain networks that support high-level cognition following brain damage in aphasia. Academy of Aphasia 53rd annual meeting, Tuscon, AZ.
  • Bonilha, L., & Fridriksson, J. (2009). Subcortical damage and white matter disconnection associated with non-fluent speech. Brain, 132(6), e108–e108. doi: 10.1093/brain/awn200
  • Bonner, M. F., & Grossman, M. (2012). Gray matter density of auditory association cortex relates to knowledge of sound concepts in primary progressive aphasia. Journal of Neuroscience, 32(23), 7986–7991. doi: 10.1523/JNEUROSCI.6241-11.2012
  • Broca, P. (1861/2006). Comments regarding the seat of the faculty of spoken language, followed by an observation of aphemia (loss of speech). In Y. Grodzinsky & K. Amunts (Eds.), Broca’s region (pp. 291–304). New York, NY: Oxford University Press.
  • Brodmann, K. (1909/1994). Localisation in the cerebral cortex: The principles of comparative localisation in the cerebral cortex based on cytoarchitectonics (L. J. Garey, Trans.). London: Smith-Gordon Company Ltd.
  • Bub, J., & Bub, D. (1988). On the methodology of single-case studies in cognitive neuropsychology. Cognitive Neuropsychology, 5(5), 565–582. doi: 10.1080/02643298808253275
  • Caplan, D. (1988). On the role of group studies in neuropsychological and pathopsychological research. Cognitive Neuropsychology, 5(5), 535–547. doi: 10.1080/02643298808253273
  • Caramazza, A. (1984). The logic of neuropsychological research and the problem of patient classification in aphasia. Brain and Language, 21(1), 9–20. doi: 10.1016/0093-934X(84)90032-4
  • Caramazza, A. (1986). On drawing inferences about the structure of normal cognitive systems from the analysis of patterns of impaired performance: The case for single-patient studies. Brain and Cognition, 5(1), 41–66. doi: 10.1016/0278-2626(86)90061-8
  • Caramazza, A. (1991). Data, statistics, and theory: A comment on Bates, McDonald, MacWhinney, and Applebaum’s “A maximum likelihood procedure for the analysis of group and individual data in aphasia research”. Brain and Language, 41(1), 43–51. doi: 10.1016/0093-934X(91)90109-E
  • Caramazza, A. (1992). Is cognitive neuropsychology possible? Journal of Cognitive Neuroscience, 4(1), 80–95. doi: 10.1162/jocn.1992.4.1.80
  • Caramazza, A., & Badecker, W. (1989). Patient classification in neuropsychological research. Brain and Cognition, 10(2), 256–295. doi: 10.1016/0278-2626(89)90056-0
  • Caramazza, A., & Hillis, A. E. (1991). Lexical organization of nouns and verbs in the brain. Nature, 349(6312), 788–790. doi: 10.1038/349788a0
  • Caramazza, A., & McCloskey, M. (1988). The case for single-patient studies. Cognitive Neuropsychology, 5(5), 517–527. doi: 10.1080/02643298808253271
  • Caspers, S., Eickhoff, S. B., Geyer, S., Scheperjans, F., Mohlberg, H., Zilles, K., & Amunts, K. (2008). The human inferior parietal lobule in stereotaxic space. Brain Structure and Function, 212(6), 481–495. doi: 10.1007/s00429-008-0195-z
  • Caspers, S., Geyer, S., Schleicher, A., Mohlberg, H., Amunts, K., & Zilles, K. (2006). The human inferior parietal cortex: Cytoarchitectonic parcellation and interindividual variability. NeuroImage, 33(2), 430–448. doi: 10.1016/j.neuroimage.2006.06.054
  • Chai, L. R., Mattar, M. G., Blank, I. A., Fedorenko, E., & Bassett, D. S. (2016). Functional network dynamics of the language system. Cerebral Cortex, 26(11), 4148–4159. doi: 10.1093/cercor/bhw238
  • Cohen, A. L., Fair, D. A., Dosenbach, N. U. F., Miezin, F. M., Dierker, D., Van Essen, D. C., … Petersen, S. E. (2008). Defining functional areas in individual human brains using resting functional connectivity MRI. NeuroImage, 41(1), 45–57. doi: 10.1016/j.neuroimage.2008.01.066
  • Crinion, J. T., & Leff, A. P. (2007). Recovery and treatment of aphasia after stroke: Functional imaging studies. Current Opinion in Neurology, 20(6), 667–673. doi: 10.1097/WCO.0b013e3282f1c6fa
  • Crosson, B., McGregor, K., Gopinath, K. S., Conway, T. W., Benjamin, M., Chang, Y.-L., … Sherod, M. G. (2007). Functional MRI of language in aphasia: A review of the literature and the methodological challenges. Neuropsychology Review, 17(2), 157–177. doi: 10.1007/s11065-007-9024-z
  • Dax, M. (1863). Observations tendant à prouver la coïncidence constante des dérangements de la parole avec une lésion de l’hémisphère gauche du cerveau. Comptes rendus de l’Académie des Sciences, 56, 536.
  • Deen, B., Koldewyn, K., Kanwisher, N., & Saxe, R. (2015). Functional organization of social perception and cognition in the superior temporal sulcus. Cerebral Cortex, 25(11), 4596–4609. doi: 10.1093/cercor/bhv111
  • Dronkers, N. F. (2000). The gratuitous relationship between Broca’s aphasia and Broca’s area. Behavioral and Brain Sciences, 23(01), 30–31. doi: 10.1017/S0140525X00322397
  • Dronkers, N. F., Wilkins, D. P., Van Valin, R. D., Redfern, B. B., & Jaeger, J. J. (2004). Lesion analysis of the brain areas involved in language comprehension. Cognition, 92(1), 145–177. doi: 10.1016/j.cognition.2003.11.002
  • Duffau, H. (2017). A two-level model of interindividual anatomo-functional variability of the brain and its implications for neurosurgery. Cortex, 86, 303–313. doi: 10.1016/j.cortex.2015.12.009
  • Duncan, J. (2010). The multiple-demand (MD) system of the primate brain: Mental programs for intelligent behaviour. Trends in Cognitive Sciences, 14(4), 172–179. doi: 10.1016/j.tics.2010.01.004
  • Eickhoff, S. B., Thirion, B., Varoquaux, G., & Bzdok, D. (2015). Connectivity-based parcellation: Critique and implications. Human Brain Mapping, 36(12), 4771–4792. doi: 10.1002/hbm.22933
  • Fedorenko, E., Behr, M. K., & Kanwisher, N. (2011). Functional specificity for high-level linguistic processing in the human brain. Proceedings of the National Academy of Sciences, 108(39), 16428–16433. doi: 10.1073/pnas.1112937108
  • Fedorenko, E., Duncan, J., & Kanwisher, N. (2012). Language-selective and domain-general regions lie side by side within Broca’s area. Current Biology, 22(21), 2059–2062. doi: 10.1016/j.cub.2012.09.011
  • Fedorenko, E., Duncan, J., & Kanwisher, N. (2013). Broad domain generality in focal regions of frontal and parietal cortex. Proceedings of the National Academy of Sciences, 110(41), 16616–16621. doi: 10.1073/pnas.1315235110
  • Fedorenko, E., Fillmore, P., Smith, K., Bonilha, L., & Fridriksson, J. (2015). The superior precentral gyrus of the insula does not appear to be functionally specialized for articulation. Journal of Neurophysiology, 113(7), 2376–2382. doi: 10.1152/jn.00214.2014
  • Fedorenko, E., Hsieh, P.-J., Nieto-Castañón, A., Whitfield-Gabrieli, S., & Kanwisher, N. (2010). New method for fMRI investigations of language: Defining ROIs functionally in individual subjects. Journal of Neurophysiology, 104(2), 1177–1194. doi: 10.1152/jn.00032.2010
  • Fedorenko, E., & Kanwisher, N. (2009). Neuroimaging of language: Why hasn’t a clearer picture emerged? Language and Linguistics Compass, 3(4), 839–865. doi: 10.1111/j.1749-818X.2009.00143.x
  • Fedorenko, E., McDermott, J. H., Norman-Haignere, S., & Kanwisher, N. (2012). Sensitivity to musical structure in the human brain. Journal of Neurophysiology, 108(12), 3289–3300. doi: 10.1152/jn.00209.2012
  • Fedorenko, E., Mineroff, Z., Siegelman, M., & Blank, I. (2017). The distinction between lexico-semantic and syntactic processing is not an organizing dimension of the human language system. CUNY sentence processing conference, Cambridge, MA.
  • Fedorenko, E., Nieto-Castañón, A., & Kanwisher, N. (2012a). Lexical and syntactic representations in the brain: An fMRI investigation with multi-voxel pattern analyses. Neuropsychologia, 50(4), 499–513. doi: 10.1016/j.neuropsychologia.2011.09.014
  • Fedorenko, E., Nieto-Castañón, A., & Kanwisher, N. (2012b). Syntactic processing in the human brain: What we know, what we don’t know, and a suggestion for how to proceed. Brain and Language, 120(2), 187–207. doi: 10.1016/j.bandl.2011.01.001
  • Fedorenko, E., Scott, T. L., Brunner, P., Coon, W. G., Pritchett, B., Schalk, G., & Kanwisher, N. (2016). Neural correlate of the construction of sentence meaning. Proceedings of the National Academy of Sciences, 113(41), E6256–E6262. doi: 10.1073/pnas.1612132113
  • Fedorenko, E., & Thompson-Schill, S. L. (2014). Reworking the language network. Trends in Cognitive Sciences, 18(3), 120–126. doi: 10.1016/j.tics.2013.12.006
  • Fischl, B., Rajendran, N., Busa, E., Augustinack, J., Hinds, O., Yeo, B. T. T., … Zilles, K. (2008). Cortical folding patterns and predicting cytoarchitecture. Cerebral Cortex, 18(8), 1973–1980. doi: 10.1093/cercor/bhm225
  • Fox, M. D., Liu, H., & Pascual-Leone, A. (2013). Identification of reproducible individualized targets for treatment of depression with TMS based on intrinsic connectivity. NeuroImage, 66, 151–160. doi: 10.1016/j.neuroimage.2012.10.082
  • Fridriksson, J., Bonilha, L., Baker, J. M., Moser, D., & Rorden, C. (2010). Activity in preserved left hemisphere regions predicts anomia severity in aphasia. Cerebral Cortex, 20(5), 1013–1019. doi: 10.1093/cercor/bhp160
  • Fridriksson, J., Richardson, J. D., Baker, J. M., & Rorden, C. (2011). Transcranial direct current stimulation improves naming reaction time in fluent aphasia. Stroke, 42(3), 819–821. doi: 10.1161/STROKEAHA.110.600288
  • Friston, K. J., Rotshtein, P., Geng, J. J., Sterzer, P., & Henson, R. N. (2006). A critique of functional localisers. Neuroimage, 30(4), 1077–1087. doi: 10.1016/j.neuroimage.2005.08.012
  • Frost, M. A., & Goebel, R. (2012). Measuring structural–functional correspondence: Spatial variability of specialised brain regions after macro-anatomical alignment. NeuroImage, 59(2), 1369–1381. doi: 10.1016/j.neuroimage.2011.08.035
  • Geranmayeh, F., Brownsett, S. L., & Wise, R. J. (2014). Task-induced brain activity in aphasic stroke patients: What is driving recovery? Brain, 137(10), 2632–2648. doi: 10.1093/brain/awu163
  • Geva, S., Jones, P. S., Crinion, J. T., Price, C. J., Baron, J.-C., & Warburton, E. A. (2011). The neural correlates of inner speech defined by voxel-based lesion–symptom mapping. Brain, 134(10), 3071–3082. doi: 10.1093/brain/awr232
  • Gloor, P. (1997). The temporal lobe and limbic system. New York, NY: Oxford University Press.
  • Grodzinsky, Y., Piñango, M. M., Zurif, E., & Drai, D. (1999). The critical role of group studies in neuropsychology: Comprehension regularities in Broca’s aphasia. Brain and Language, 67(2), 134–147. doi: 10.1006/brln.1999.2050
  • Hamilton, R. H., Chrysikou, E. G., & Coslett, B. (2011). Mechanisms of aphasia recovery after stroke and the role of noninvasive brain stimulation. Brain and Language, 118(1), 40–50. doi: 10.1016/j.bandl.2011.02.005
  • Heiss, W.-D., & Thiel, A. (2006). A proposed regional hierarchy in recovery of post-stroke aphasia. Brain and Language, 98(1), 118–123. doi: 10.1016/j.bandl.2006.02.002
  • Hickok, G., Buchsbaum, B., Humphries, C., & Muftuler, T. (2003). Auditory–motor interaction revealed by fMRI: Speech, music, and working memory in area Spt. Journal of Cognitive Neuroscience, 15(5), 673–682. doi: 10.1162/089892903322307393
  • Hillis, A. E., Work, M., Barker, P. B., Jacobs, M. A., Breese, E. L., & Maurer, K. (2004). Re-examining the brain regions crucial for orchestrating speech articulation. Brain, 127(7), 1479–1487. doi: 10.1093/brain/awh172
  • Humphreys, G. F., & Gennari, S. P. (2014). Competitive mechanisms in sentence processing: Common and distinct production and reading comprehension networks linked to the prefrontal cortex. NeuroImage, 84, 354–366. doi: 10.1016/j.neuroimage.2013.08.059
  • Hung, Y.-H., Pallier, C., Dehaene, S., Lin, Y.-C., Chang, A., Tzeng, O. J.-L., & Wu, D. H. (2015). Neural correlates of merging number words. NeuroImage, 122, 33–43. doi: 10.1016/j.neuroimage.2015.07.045
  • January, D., Trueswell, J. C., & Thompson-Schill, S. L. (2009). Co-localization of Stroop and syntactic ambiguity resolution in Broca’s area: Implications for the neural basis of sentence processing. Journal of Cognitive Neuroscience, 21(12), 2434–2444. doi: 10.1162/jocn.2008.21179
  • Jones, E. G., & Powell, T. P. (1970). An anatomical study of converging sensory pathways within the cerebral cortex of the monkey. Brain, 93(4), 793–820. doi: 10.1093/brain/93.4.793
  • Juch, H., Zimine, I., Seghier, M. L., Lazeyras, F., & Fasel, J. H. (2005). Anatomical variability of the lateral frontal lobe surface: Implication for intersubject variability in language neuroimaging. NeuroImage, 24(2), 504–514. doi: 10.1016/j.neuroimage.2004.08.037
  • Julian, J. B., Fedorenko, E., Webster, J., & Kanwisher, N. (2012). An algorithmic method for functionally defining regions of interest in the ventral visual pathway. NeuroImage, 60(4), 2357–2364. doi: 10.1016/j.neuroimage.2012.02.055
  • Jung-Beeman, M. (2005). Bilateral brain processes for comprehending natural language. Trends in Cognitive Sciences, 9(11), 512–518. doi: 10.1016/j.tics.2005.09.009
  • Kakuda, W., Abo, M., Kaito, N., Watanabe, M., & Senoo, A. (2010). Functional MRI-based therapeutic rTMS strategy for aphasic stroke patients: A case series pilot study. International Journal of Neuroscience, 120(1), 60–66. doi: 10.3109/00207450903445628
  • Kanwisher, N., McDermott, J., & Chun, M. M. (1997). The fusiform face area: A module in human extrastriate cortex specialized for face perception. Journal of Neuroscience, 17(11), 4302–4311.
  • Kiran, S., Ansaldo, A., Bastiaanse, R., Cherney, L. R., Howard, D., Faroqi-Shah, Y., … Thompson, C. K. (2013). Neuroimaging in aphasia treatment research: Standards for establishing the effects of treatment. Neuroimage, 76, 428–435. doi: 10.1016/j.neuroimage.2012.10.011
  • Li, K., Langley, J., Li, Z., & Hu, X. P. (2015). Connectomic profiles for individualized resting state networks and regions of interest. Brain Connectivity, 5(2), 69–79. doi: 10.1089/brain.2014.0229
  • Lichtheim, L. (1885). On aphasia. Brain, 7, 433–484. doi: 10.1093/brain/7.4.433
  • Mahowald, K., & Fedorenko, E. (2016). Reliable individual-level neural markers of high-level language processing: A necessary precursor for relating neural variability to behavioral and genetic variability. NeuroImage, 139, 74–93. doi: 10.1016/j.neuroimage.2016.05.073
  • Mather, M., Cacioppo, J. T., & Kanwisher, N. (2013). How fMRI can inform cognitive theories. Perspectives on Psychological Science, 8(1), 108–113. doi: 10.1177/1745691612469037
  • McCloskey, M., & Caramazza, A. (1988). Theory and methodology in cognitive neuropsychology: A response to our critics. Cognitive Neuropsychology, 5(5), 583–623. doi: 10.1080/02643298808253276
  • Meinzer, M., Beeson, P. M., Cappa, S., Crinion, J., Kiran, S., Saur, D., … Thompson, C. K. (2013). Neuroimaging in aphasia treatment research: Consensus and practical guidelines for data analysis. Neuroimage, 73, 215–224. doi: 10.1016/j.neuroimage.2012.02.058
  • Meinzer, M., & Breitenstein, C. (2008). Functional imaging studies of treatment-induced recovery in chronic aphasia. Aphasiology, 22(12), 1251–1268. doi: 10.1080/02687030802367998
  • Meinzer, M., Harnish, S., Conway, T., & Crosson, B. (2011). Recent developments in functional and structural imaging of aphasia recovery after stroke. Aphasiology, 25(3), 271–290. doi: 10.1080/02687038.2010.530672
  • Menenti, L., Gierhan, S. M. E., Segaert, K., & Hagoort, P. (2011). Shared language overlap and segregation of the neuronal infrastructure for speaking and listening revealed by functional MRI. Psychological Science, 22(9), 1173–1182. doi: 10.1177/0956797611418347
  • Mesulam, M.-M., Thompson, C. K., Weintraub, S., & Rogalski, E. J. (2015). The Wernicke conundrum and the anatomy of language comprehension in primary progressive aphasia. Brain, 138(8), 2423–2437. doi: 10.1093/brain/awv154
  • Mikl, M., Mareček, R., Hluštík, P., Pavlicová, M., Drastich, A., Chlebus, P., … Krupa, P. (2008). Effects of spatial smoothing on fMRI group inferences. Magnetic Resonance Imaging, 26(4), 490–503. doi: 10.1016/j.mri.2007.08.006
  • Mirman, D., Chen, Q., Zhang, Y., Wang, Z., Faseyitan, O. K., Coslett, H. B., & Schwartz, M. F. (2015). Neural organization of spoken language revealed by lesion-symptom mapping. Nature Communications, 6, 6762. doi: 10.1038/ncomms7762
  • Naeser, M. A., Martin, P. I., Nicholas, M., Baker, E. H., Seekins, H., Kobayashi, M., … Kurland, J. (2005). Improved picture naming in chronic aphasia after TMS to part of right Broca’s area: An open-protocol study. Brain and Language, 93(1), 95–105. doi: 10.1016/j.bandl.2004.08.004
  • Neville, H. J., Bavelier, D., Corina, D., Rauschecker, J., Karni, A., Lalwani, A., … Turner, R. (1998). Cerebral organization for language in deaf and hearing subjects: Biological constraints and effects of experience. Proceedings of the National Academy of Sciences, 95(3), 922–929. doi: 10.1073/pnas.95.3.922
  • Newcombe, F., & Marshall, J. C. (1988). Idealisation meets psychometrics: The case for the right groups and the right individuals. Cognitive Neuropsychology, 5(5), 549–564. doi: 10.1080/02643298808253274
  • Newhart, M., Ken, L., Kleinman, J. T., Heidler-Gary, J., & Hillis, A. E. (2007). Neural networks essential for naming and word comprehension. Cognitive and Behavioral Neurology, 20(1), 25–30. doi: 10.1097/WNN.0b013e31802dc4a7
  • Nieto-Castañón, A., & Fedorenko, E. (2012). Subject-specific functional localizers increase sensitivity and functional resolution of multi-subject analyses. NeuroImage, 63(3), 1646–1669. doi: 10.1016/j.neuroimage.2012.06.065
  • Overath, T., McDermott, J. H., Zarate, J. M., & Poeppel, D. (2015). The cortical analysis of speech-specific temporal structure revealed by responses to sound quilts. Nature Neuroscience, 18(6), 903–911. doi: 10.1038/nn.4021
  • Pitcher, D., Charles, L., Devlin, J. T., Walsh, V., & Duchaine, B. (2009). Triple dissociation of faces, bodies, and objects in extrastriate cortex. Current Biology, 19(4), 319–324. doi: 10.1016/j.cub.2009.01.007
  • Poldrack, R. A. (2006). Can cognitive processes be inferred from neuroimaging data? Trends in Cognitive Sciences, 10(2), 59–63. doi: 10.1016/j.tics.2005.12.004
  • Poldrack, R. A. (2011). Inferring mental states from neuroimaging data: From reverse inference to large-scale decoding. Neuron, 72(5), 692–697. doi: 10.1016/j.neuron.2011.11.001
  • Prado, J., Mutreja, R., & Booth, J. R. (2013). Fractionating the neural substrates of transitive reasoning: Task-dependent contributions of spatial and verbal representations. Cerebral Cortex, 23(3), 499–507. doi: 10.1093/cercor/bhr389
  • Price, C. J., Crinion, J., & Friston, K. J. (2006). Design and analysis of fMRI studies with neurologically impaired patients. Journal of Magnetic Resonance Imaging, 23(6), 816–826. doi: 10.1002/jmri.20580
  • Rapp, B., Caplan, D., Edwards, S., Visch-Brink, E., & Thompson, C. K. (2013). Neuroimaging in aphasia treatment research: Issues of experimental design for relating cognitive to neural changes. Neuroimage, 73, 200–207. doi: 10.1016/j.neuroimage.2012.09.007
  • Rapp, B., & Caramazza, A. (2002). Selective difficulties with spoken nouns and written verbs: A single case study. Journal of Neurolinguistics, 15(3), 373–402. doi: 10.1016/S0911-6044(01)00040-9
  • Redcay, E., Velnoskey, K. R., & Rowe, M. L. (2016). Perceived communicative intent in gesture and language modulates the superior temporal sulcus. Human Brain Mapping, 37(10), 3444–3461. doi: 10.1002/hbm.23251
  • Robertson, L. C., Knight, R. T., Rafal, R., & Shimamura, A. P. (1993). Cognitive neuropsychology is more than single-case studies. Journal of Experimental Psychology: Learning, Memory, and Cognition, 19(3), 710–717. doi: 10.1037/0278-7393.19.3.710
  • Rorden, C., & Karnath, H.-O. (2004). Using human brain lesions to infer function: A relic from a past era in the fMRI age? Nature Reviews Neuroscience, 5(10), 812–819. doi: 10.1038/nrn1521
  • Rosenbaum, R. S., Gilboa, A., & Moscovitch, M. (2014). Case studies continue to illuminate the cognitive neuroscience of memory. Annals of the New York Academy of Sciences, 1316(1), 105–133. doi: 10.1111/nyas.12467
  • Saxe, R., Brett, M., & Kanwisher, N. (2006). Divide and conquer: A defense of functional localizers. NeuroImage, 30(4), 1088–1096. doi: 10.1016/j.neuroimage.2005.12.062
  • Saygin, Z. M., Osher, D. E., Koldewyn, K., Reynolds, G., Gabrieli, J. D., & Saxe, R. R. (2012). Anatomical connectivity patterns predict face selectivity in the fusiform gyrus. Nature neuroscience, 15(2), 321–327. doi: 10.1038/nn.3001
  • Scheperjans, F., Eickhoff, S. B., Hömke, L., Mohlberg, H., Hermann, K., Amunts, K., & Zilles, K. (2008). Probabilistic maps, morphometry, and variability of cytoarchitectonic areas in the human superior parietal cortex. Cerebral Cortex, 18(9), 2141–2157. doi: 10.1093/cercor/bhm241
  • Scott, T. L., Gallée, J., & Fedorenko, E. (2016). A new fun and robust version of an fMRI localizer for the frontotemporal language system. Cognitive Neuroscience. doi: 0.1080/17588928.2016.1201466
  • Sereno, M. I., Dale, A., Reppas, J., & Kwong, K. (1995). Borders of multiple visual areas in humans revealed by functional magnetic resonance imaging. Science, 268(5212), 889–893. doi: 10.1126/science.7754376
  • Shallice, T. (1979). Case study approach in neuropsychological research. Journal of Clinical Neuropsychology, 1(3), 183–211. doi: 10.1080/01688637908414450
  • Sharp, D. J., Turkheimer, F. E., Bose, S. K., Scott, S. K., & Wise, R. J. (2010). Increased frontoparietal integration after stroke and cognitive recovery. Annals of Neurology, 68(5), 753–756. doi: 10.1002/ana.21866
  • Stoppelman, N., Harpaz, T., & Ben-Shachar, M. (2013). Do not throw out the baby with the bath water: Choosing an effective baseline for a functional localizer of speech processing. Brain and Behavior, 3(3), 211–222. doi: 10.1002/brb3.129
  • Tahmasebi, A. M., Davis, M. H., Wild, C. J., Rodd, J. M., Hakyemez, H., Abolmaesumi, P., & Johnsrude, I. S. (2012). Is the link between anatomical structure and function equally strong at all cognitive levels of processing? Cerebral Cortex, 22(7), 1593–1603. doi: 10.1093/cercor/bhr205
  • Thompson, C. K., & den Ouden, D.-B. (2008). Neuroimaging and recovery of language in aphasia. Current Neurology and Neuroscience Reports, 8(6), 475–483. doi: 10.1007/s11910-008-0076-0
  • Tie, Y., Rigolo, L., Ozdemir Ovalioglu, A., Olubiyi, O., Doolin, K. L., Mukundan, S., & Golby, A. J. (2015). A new paradigm for individual subject language mapping: Movie-watching fMRI. Journal of Neuroimaging, 25(5), 710–720. doi: 10.1111/jon.12251
  • Tomaiuolo, F., MacDonald, J. D., Caramanos, Z., Posner, G., Chiavaras, M., Evans, A. C., & Petrides, M. (1999). Morphology, morphometry and probability mapping of the pars opercularis of the inferior frontal gyrus: An in vivo MRI analysis. European Journal of Neuroscience, 11(9), 3033–3046. doi: 10.1046/j.1460-9568.1999.00718.x
  • Tootell, R. B., Reppas, J. B., Kwong, K. K., Malach, R., Born, R. T., Brady, T. J., … Belliveau, J. W. (1995). Functional analysis of human MT and related visual cortical areas using magnetic resonance imaging. Journal of Neuroscience, 15(4), 3215–3230.
  • Turkeltaub, P. E., Coslett, H. B., Thomas, A. L., Faseyitan, O., Benson, J., Norise, C., & Hamilton, R. H. (2012). The right hemisphere is not unitary in its role in aphasia recovery. Cortex, 48(9), 1179–1186. doi: 10.1016/j.cortex.2011.06.010
  • Turkeltaub, P. E., Messing, S., Norise, C., & Hamilton, R. H. (2011). Are networks for residual language function and recovery consistent across aphasic patients? Neurology, 76(20), 1726–1734. doi: 10.1212/WNL.0b013e31821a44c1
  • van Hees, S., McMahon, K., Angwin, A., de Zubicaray, G., & Copland, D. A. (2014). Neural activity associated with semantic versus phonological anomia treatments in aphasia. Brain and Language, 129, 47–57. doi: 10.1016/j.bandl.2013.12.004
  • van Hees, S., McMahon, K., Angwin, A., de Zubicaray, G., Read, S., & Copland, D. A. (2014). A functional MRI study of the relationship between naming treatment outcomes and resting state functional connectivity in post-stroke aphasia. Human Brain Mapping, 35(8), 3919–3931. doi: 10.1002/hbm.22448
  • Van Orden, G. C., Pennington, B. F., & Stone, G. O. (2001). What do double dissociations prove? Cognitive Science, 25(1), 111–172. doi: 10.1207/s15516709cog2501_5
  • Varley, R. (1998). Aphasia language, aphasic thought: An investigation of propositional thinking in an a-propositional aphasic. In P. Carruthers, & J. Boucher (Eds.), Language and thought: Interdisciplinary themes (pp. 128–145). Cambridge: Cambridge University Press.
  • Veldsman, M., Cumming, T., & Brodtmann, A. (2015). Beyond BOLD: Optimizing functional imaging in stroke populations. Human Brain Mapping, 36(4), 1620–1636. doi: 10.1002/hbm.22711
  • Wernicke, C. (1874/1969). The symptom complex of aphasia: A psychological study on an anatomical basis. In R. S. Cohen, & M. W. Wartofsky (Eds.), Boston studies in the philosophy of science (pp. 34–97). Dordrecht: D. Reidel Publishing.
  • Whitaker, H. A., & Slotnick, H. B. (1988). Comments on “the case for single patient studies”: Is (neuro) psychology possible? Cognitive Neuropsychology, 5(5), 529–533. doi: 10.1080/02643298808253272
  • Wilson, S. M. (2016). Lesion-symptom mapping in the study of spoken language understanding. Language, Cognition and Neuroscience, 32, 891–899. doi: 10.1080/23273798.2016.1248984
  • Wilson, S. M., Bautista, A., Yen, M., Lauderdale, S., & Eriksson, D. K. (2016). Validity and reliability of four language mapping paradigms. NeuroImage: Clinical, 16, 399–408. doi: 10.1016/j.nicl.2016.03.015
  • Wise, R. J. S., Scott, S. K., Blank, S. C., Mummery, C. J., Murphy, K., & Warburton, E. A. (2001). Separate neural subsystems within “Wernicke’s area”. Brain, 124(1), 83–95. doi: 10.1093/brain/124.1.83
  • Yarkoni, T., Poldrack, R. A., Nichols, T. E., Van Essen, D. C., & Wager, T. D. (2011). Large-scale automated synthesis of human functional neuroimaging data. Nature Methods, 8(8), 665–670. doi: 10.1038/nmeth.1635
  • Yarkoni, T., Poldrack, R. A., Van Essen, D. C., & Wager, T. D. (2010). Cognitive neuroscience 2.0: Building a cumulative science of human brain function. Trends in Cognitive Sciences, 14(11), 489–496. doi: 10.1016/j.tics.2010.08.004
  • Young, L., Camprodon, J. A., Hauser, M., Pascual-Leone, A., & Saxe, R. (2010). Disruption of the right temporoparietal junction with transcranial magnetic stimulation reduces the role of beliefs in moral judgments. Proceedings of the National Academy of Sciences, 107(15), 6753–6758. doi: 10.1073/pnas.0914826107
  • Zurif, E., Gardner, H., & Brownell, H. H. (1989). The case against the case against group studies. Brain and Cognition, 10(2), 237–255. doi: 10.1016/0278-2626(89)90055-9
  • Zurif, E., Swinney, D., & Fodor, J. A. (1991). An evaluation of assumptions underlying the single-patient-only position in neuropsychological research: A reply. Brain and Cognition, 16(2), 198–210. doi: 10.1016/0278-2626(91)90006-T

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