Intraliposomal chemical activation patterns of liposomal cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum (II) (L-NDDP)-a potential antitumour agent

References

• CHANEY, S. G., WYRICK, S. D., and TILL, G. K., 1990, In vitro biotransformations of tetrachloro( DJ, tran s)- 2- diam inocyclohexanep latinum (I V) (tetraplatinum) in rat plasma. Cancer Research, 50, 4539–4545.
   PubMedGoogle Scholar
• HAN, I., KHOKHAR, A. R., and PEREZ- SOLER, R., 1996, Intraliposomal conversion of lip op hilic ci s- b is- carb oxylato- tran s- R, R- 1,2- diam inocyclohexane- p latin um (II) complexes into cis- b is- dichloro-trans-R, R-1, 2- diaminocyclohexane- p latin um (II). Cancer Chemotherapy Pharmacology, 39, 17–24.
   PubMedGoogle Scholar
• KHOKHAR, A. R., AL-BAKER, S., BROWN, T., and PEREZ- SOLER, R., 1991, Chemical and biological studies on a series of lipid-soluble (trans-(R,R)- and (S,S)-1,2-diaminocyclohexane)platinum(II) complexes incorporated in liposomes. Journal of Medical Chemistry, 34, 325–329.
   PubMedGoogle Scholar
• KHOKHAR, A. R., AL-BAKER, S. KRAKOFF, I. H., and PEREZ- SOLER, R., 1989, Toxicity and antitumor activity of cis- b is- carb oxylato(trans- R,R - 1,2- diaminocyclohexane)-platinum(H) complexes entrapped in liposomes. Cancer Chemotherapy Pharmacology, 23, 219–224.
   PubMedGoogle Scholar
• KHOKHAR, A. R., AL-BAKER, S., and PEREZ- SOLER, R., 1992, Toxicity and efficacy studies on a series of lipid-soluble dineodecanoato(trans-R,R- and trans-S,S-1,2-diamino-cyclohexane)platinum(H) complexes entrapped in liposomes. AntiCancer Drugs, 3, 95–100.
   PubMedGoogle Scholar
• LEN', F., 1996a, Chronopharmacologie et chronothérapie des cancers. Pathologie Biologie, 44, 631–644 [French].
   PubMedGoogle Scholar
• Ulu, F., 1996b, Chromotherapy for gastrointestinal cancers. Current Opinions in Oncology, 8, 334–341.
   PubMedGoogle Scholar
• Luo, F. R., STANK°, J., and CHANEY, S. G., 1998, Pharmacokinetical and neurotoxicological comparison of oxaliplatin, ormaplatin, and their biotransformation products. Proceedings of the American Association for Cancer Research, 39, abstract number 4058.
   Google Scholar
• MAULDIN, S. K., GIBBONS, G., WYRICK, S. D., and CHANEY, S. G., 1988a, Intracellular biotransformation of platinum compounds with the 1,2-diaminocyclohexane carrier ligand in the L1210 cell line. Cancer Research, 48, 5136–5144.
   PubMedGoogle Scholar
• MAULDIN, S. K., PLESCIA, M., RICHARD, F. A., WYRICK S. D., VOYKSNER, R. D., and CHANEY, S. G., 1988b, Displacement of the bidentate malonate ligand from (D,L-1,2-diaminocyclohexane)malonateplatinum(H) by physiologically important com-pounds in vitro. Biochemical Pharmacology, 37, 3321–3333.
   PubMedGoogle Scholar
• NORTHCOTT, S. E., MARR, J. G. D., SECREAST, S. L., HAN, F., and DEZWAAN, J., 1991, Solution chemistry and analytical characterization of ormaplatin. Journal of Pharmaceutical and Biomedical Analysis, 9, 1009–1018.
   PubMedGoogle Scholar
• PEREZ- SOLER, R., and KHOKHAR, A. R., 1992, Lipophilic cisplatin analogues entrapped in liposomes: role of intraliposomal drug activation in biological activity. Cancer Research, 52, 6341–6347.
   PubMedGoogle Scholar
• PEREZ- SOLER, R., FRANCIS, K., AL-BAKER, S., PILKIEWICZ, F., and KHOKHAR, A. R., 1994a, Preparation and characterization of liposomes containing a lipophilic cisplatin derivative for clinical use. Journal of Microencapsulation, 11, 41–54.
   PubMedGoogle Scholar
• PEREZ- SOLER, R., HAN, I., AL-BAKER, S., and KHOKHAR, A. R., 1994b, Lipophilic platinum complexes entrapped in liposomes: improved stability and preserved antitumor activity with complexes containing linear alkyl crarboxylato leaving groups. Cancer Chemotherapy Pharmacology, 33, 378–384.
   PubMedGoogle Scholar
• PEREZ- SOLER, R., KHOKHAR A. R., and LOPEZ- BERESTEIN, G., 1987, Treatment and prophylaxis of experimental liver metastases of M5076 reticulosarcoma with cis-bis-neodecanoato-trans-R,R- 1,2- diam inocyclohexanep latinum (II) encapsulated in multilamellar vesicles. Cancer Research, 47, 6462–6466.
   PubMedGoogle Scholar
• PEREZ- SOLER, R., LOPEZ- BERESTEIN, G., LAUTERSZTAIN, J. et al. 1990, Phase I clinical and pharmacological study of liposome entrapped cis-bis-neodecanoato-trans-R,R-1,2-diamminocyclohexaneplatinum (II). Cancer Research, 50, 4254–4259.
   PubMedGoogle Scholar
• PEREZ- SOLER, R., SHIN, D. M., SIDDIK, Z. H., MURPHY, W. K., HUBER, M., LEE, J. S., KHOKHAR, A. R., and HONG, W. K., 1997, Phase I clinical and pharmacological study of liposome-entrapped NDDP administered intrapleurally in patients with malignant pleural effusions. Clinical Cancer Research, 3, 373–379.
   PubMedGoogle Scholar
• PEREZ- SOLER, R., YANG, L. Y., DREWINKO, B., LAUTERSZTAIN, J., and KHOKHAR, A. R., 1988, Increased cytotoxicity and reversal of resistance to cis-diamminedichloroplatinum (II) with entrapment of cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum (II) in multilamellar lipid vessels. Cancer Research, 48, 4509–4512.
   PubMedGoogle Scholar
• SCRENCI, D., ER, H. M., HAMBLEY, T. W., GALETTIS, P., BROUWER, W., and MCKEAGE, M. J., 1997, Stereoselective peripheral sensory neurotoxicity of diaminocyclohexane platinum enantiomers related to ormaplatin and oxaliplatin: British Journal of Cancer, 76, 502–510.
   PubMedGoogle Scholar
• SEARS, B., 1983, Hydrophobic platinum compounds and their preparation. European Patent Application 0 113 508.
   Google Scholar
• SoumE, P., RAYMOND, E., BRIENZA, S., and CVITKOVIC, E., 1997, Oxaliplatine: le premier DACH platine en clinique. Bulletin Cancer, 84, 665–673 [French].
   PubMedGoogle Scholar