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Research Article

Improvement of encapsulation efficiency of water-in-oil-inwater emulsion with hypertonic inner aqueous phase

Pages 19-28 | Published online: 29 Sep 2008

References

  • COLE, M. L., and WHATELEY, T. L., 1997, Release rate profiles of theophylline and insulin from stable multiple w/o/w emulsions. Journal of Controlled Release, 49, 51–58.
  • CUNHA, A. S., CHRRON, M., GROSSIORD, J. L., PUISIEUX, F., and SEILLER, M., 1998, W/O/W multiple emulsions of insulin containing a protease inhibitor and an absorption enhancer: biological activity after oral administration to normal and diabetic rats. International Journal of Pharmaceutics, 169, 33–44.
  • DE LUCA, M., GROSSIORD, J. L., MÉDARD, J. M., VAUTION, C., and SEILER, M., 1990, A stable w/o/w multiple emulsion. Cosmetics & Toiletries, 105, 65–69.
  • DICKINSON, E., EVISON, J., and Owusu, R. K., 1991, Preparation of fine protein-stabilized water-in-oil-in-water emulsions. Food Hydrocolloids, 5, 481–485.
  • FLORENCE, A. T., and WHITEHILL, D., 1985, Stability and stabilization of water-in-oil-in-water multiple emulsions. In Macro- and micro emulsions: Theory and application, edited by D. 0. Shar, ACS Symposium Series, No. 272, American Chemical Society, Washington, pp. 359–380.
  • FRENKEL, M., SHWARTZ, R., and GARTI, N., 1983, Multiple emulions. I. Stability: inversion, apparent and weighted HLB. Journal of Colloid and Interface Science, 94, 174–178.
  • GARTI, N., MAGDASSI, S., and WHITEHILL, D., 1985, Transfer phenomena across the oil phase in water-oil-water multiple emulsions evaluated by Coulter Counter. 1. Effect of emulsifier 1 on water permeability. Jornal of Colloid and Interface Science, 104, 587–591.
  • HINO, T., SHIMABAYASHI, S., KAWASHIMA, Y., TAKEUCHI, H., YAMAMOTO, H., Isozmu, M., NAKANO, S., YAMAZAKI, F., KUMADA, T., and SASSA, T., 1999, Comparison of lipiodol water-in-oil-in-water emulsion with oil-in-water emulsion : acute toxicity and deposition in liver after hepatic arterial administration in rats. Phamacy Pharmacology Communications, 5, 355–359.
  • KAWASHIMA, Y., HINO, T., TAKEUCHI, H., and NIWA, T., 1992, Stabilization of water/oil/ water multiple emulsion with hypertonic inner aqueous phase. Chemical & Pharmaceutical Bulletin, 40, 1240–1246.
  • KITA, Y., MATSUMOTO, S., and YONEZAWA, D., 1978, Permeation of water through the oil layer in w/o/w-type multiple-phase emulsions. Journal of Japanese Chemical Society, 1978, 11–14.
  • MATSUMOTO, S., KITA, Y., and YONEZAWA, D., 1976, An attempt at preparing water-in-oil-in-water multiple-phase emulsions. Journal of Colloid and Interface Science, 57, 353–361.
  • MOONEY, M., 1951, The viscosity of a concentrated suspension of spherical particles. Journal of Colloid Science, 6, 162–170.
  • OMOTOSHO, J. A., FLORENCE, A. T., and WHATELEY, T. L., 1990, Absorption and lymphatic uptake of 5-flourouracil in the rat following oral administration of w/o/w multiple emulsions. International Journal of Pharmaceutics, 61, 51–56.
  • OMOTOSHO, J. A., WHATELY, T. L., and FLORENCE, A. T., 1989, Methotrexate transport from the internal phase of multiple w/o/w emulsions. Journal of Mkroencapsulation, 6, 183–192.
  • PIEMI, M. P. Y., DE LUCA, M., GROSSIORD, J. L., SEILLER, M., and MARTY, J. P., 1998, Transdermal delivery of glucose through hairless rat skin in vitro: effect of multiple and simple emulsions. International Journal of Pharmaceutics, 171, 207–215.
  • SILVA-CUNHA, A., CHERON, M., GROSSIORD, J. L., PUISIEUX, F., and SEILER, M., 1998, W/O/VV multiple emulsions of insulin containing a protease inhibitor and an absorpiton enhancer: biological acitivity after oral administration to nomal and diabetic rats. International Journal of Pharmaceutics, 169, 33–44.

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