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Journal of Microencapsulation
Micro and Nano Carriers
Volume 18, 2001 - Issue 1
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Research Article

Long-acting delivery microspheres of levo-norgestrolpoly(3-hydroxybutyrate): their preparation, characterization and contraceptive tests on mice

B. Lu, Z. R. Wang, H. Yang School of Pharmacy, West China University of Medical Sciences, Chengdu 610041, China
Pages 55-64 | Published online: 29 Sep 2008

References

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  • ATKINS, T. W., 1997b, Fabrication of microspheres using blends of poly(ethylene adipate) and poly(ethyleneadipate)/poly(hydroxybutyrate-hydroxyvalerate) with poly(capro-lactone): incorporation and release of bovine serum albumin. Journal of Biomaterials Science Polymer Education, 8, 833–845.
  • GOGOLEWSKI S., JOVANOVIC, M., PERREN, S. M., DILLON, J. G., and HUGHES, M. K., 1993, Tissue response and in vivo degradation of selected polyhydroxyacids: polylactides (PLA), poly(3-hydroxybutyrate) (PHB), and poly(3-hydroxybutyrate-co-3-hydro-xyvalerate) (PHB/VA). Journal of Biomedical Materials Research, 27, 1135–1148.
  • GURSEL, I., and HASIRCI, V., 1995, Properties and drug release behaviour of poly(3-hydroxybutyric acid) and various poly(3-hydroxybutyrate-hydroxyvalerate) copo-lymer microcapsules. Journal of Microencapsulation, 12, 185–193.
  • HARRISON, S. T., CHASE, H. A., AMOR, S. R., BONTHRONE, K. M., and SANDERS, J. K., 1992, Plasticization of poly(hydroxybutyrate) in vivo. International journal of Biological Macromolecules, 14, 50–56.
  • HUANG, R., and REUSCH, R. N., 1996, Poly(3-hydroxybutyrate) is associated with specific proteins in the cytoplasm and membranes of Escherichia coli. Journal of Biological Chemistry, 271, 22196–22202.
  • KNOWLES, J. C., HASTINGS, G. W., OHTA, H., NIWA, S., and BOEREE, N., 1992, Development of a degradable composite for orthopaedic use: in vivo biochemical and histological evaluation of two biactive degradable composite based on the polyhydroxy-butyrate polymer. Biomaterials, 13, 491–496.
  • KOYAMA, N., and Doi, Y., 1995, Morphology and biodegradability of a binary blend of poly((R)-3-hydroxybutyric acid) and poly((R,S)-lactic acid). Canadian Journal of Microbiology, 41, (Suppl 1), 316–322.
  • LEI, Y., and Lu, B., 1993, Studies on preparation technology of microspheres of contraceptives. Acta Pharmaceutica Sinica, 28, 296–301.
  • Lu, B., Guo, R. L., and Liu, C., 1992, Studies on an injection of microencapsulated levo-norgestrel In Microencapsulation of Drugs, edited by T. L. Whateley (Reading, Berkshire, UK: Harwood academic publishers), pp. 103–121.
  • Xu, K. T., and ZHAO, S. J., 1995, Biomedical applications of poly(0-hydroxybutyrate). Chinese Journal of Applied Environmental Biology, 1, 85–91.

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