37
Views
14
CrossRef citations to date
0
Altmetric
Research Article

Bioadhesive fluorescent microspheres as visible carriers for local delivery of drugs. I: preparation and characterization of insulin-loaded PCEFB/PLGA microspheres

&
Pages 451-461 | Published online: 29 Sep 2008

  • CARINO, G. P, JACOB, J. S., and MATHIOWITZ, E., 2000, Nanosphere based oral insulin delivery. Journal of Controlled Release, 65, 261-269.
  • CHICKERINO, D., JACOB, J., and MATHIOWITZ, E., 1996, Poly(fumaric-co-sebacic) microspheres as oral drug delivery system. Biotechnology and Bioengineering, 52, 96-101.
  • DELIE, F., 1998, Evaluation of nano- and microparticle uptake by the gastrointestinal tract. Advances in Drug Delivery Review, 34, 221-233.
  • FLYNN, M. A., VODOVOTZ, Y., KORNOWSKI, R., EPSTEIN, S., GORDON, D., and REISER, J. A., 2000, Use of fluorescent microspheres to localize in vivo gene transfer at injection sites. BioTechniques, 28, 470-474.
  • HORA, M. S., RANA, R. S., NUNBERG, H., TICE, T. R., GILLEY, R. M., and HUDSON, M. E., 1990, Release of human serum albumin from poly(lactide-co-glycolide) microspheres. Pharmaceutical Research, 7, 1190-1194.
  • JANI, P., HALBERT, G. W., LANORIDOE, J., and FLORENCE, A. T., 1989, The uptake and translocation of latex nanospheres and microspheres after oral administer to rats. Journal of Pharmaceutics and Pharmacology, 41, 809-812.
  • JEFFERY, H., DAVIS, S. S., and O'HAGAN, D. T., 1993, The preparation and characterization of poly(lactide-co-glycolide) microparties. II. The entrapment of a model protein using a (water-in-oil)-in-water emulsion solvent evaporation technique. Pharmaceutical Research, 10, 363-368.
  • JIANG, H. L., TANG, G. P., WENG, L. H., and ZHU, K. J., 2001b, In vivo degradation and biocompatibility of a new class of alternate poly(ester-anhydrides) based on aliphatic and aromatic diacids. Journal of Biomaterial Science: Polymer Edition, 12, 1281-1292.
  • JIANG, H. L., ZHU, K. J., and DAI, L. J., 2001a, New biodegradable fluorescing polyanhydrides based on aliphatic and aromatic diadics. Macromolecular Rapid Communications, 22, 414-417.
  • JIANG, H. L., ZHU, K. J., and DAI, L. J., 2001c, Synthesis and characterization of new biodegradable fluorescing poly(amide-anhydrides). Polymer International, 50, 1-6.
  • KATZ, L. C., BURKHALTER, A., and DREYER, W. J., 1984, Fluorescent latex microspheres as a retrograde neuronal marker for in vivo and in vitro studies of visual cortex. Nature, 9, 498-500.
  • LINCOFF, A. M., TOPOL, E. J., and ELLIS, S. G., 1994, Local drug delivery for the prevention of restenosis: fact, fancy and future. Circulation, 90, 2070-2084.
  • MADISON, R., MACKLIS, J. D., and THIES, C., 1990, Latex nanosphere delivery system (LNDS): novel nanometer-sized carriers of fluorescent dyes and active agents selectively target neuronal subpopulations via uptake and retrograde transport. Brain Research, 522, 90-98.
  • NIWA, T., TAKEUCHI, H., HINO, T., KUNOU, N., and KAWASHIMA, Y., 1993, Preparations of biodegradable nanospheres of water-soluble and insoluble drugs with D,L-lactide/ glycolide copolymer by a novel spontaneous emulsification solvent diffusion method, and the drug release behavior. Journal of Controlled Release, 25, 89-98.
  • PEAN, J.-M., VENIER-JULIENNE, M.-C., BOURY, F., MENEI, P., DENIZOT, B., and BENOIT, J.-P., 1998, NGF release from poly(D,L-lactide-co-glycolide) microspheres: effect of some formulation parameters on entrapsulated NGF stability. Journal of Controlled Release, 56, 175-187.
  • QUATTROCHI, J. J., MAMELAK, A. N., MADISON, R. D., MACKLIS, J. D., and HOBSON, J. A., 1989, Mapping neuronal inputs to REM sleep induction sites with carbocholfluorescent microspheres. Science, 245, 984-986.
  • ROJAS, J., PINTO-ALPHANDARY, H., LEO, E., PEEQUET, S., COURVEUR, P., GULIK, A., and FATTAL, E., 1999, A polysorbate-based non-ionic surfactant can modulate loading and release of ß3-lactoglobulin entrapped in multiphase poly(DL-lactide-co-glycolide) microspheres. Pharmaceutical Research, 16, 255-260.
  • SONG, C., LABHASETWAR, V., MURPHY, H., Qu, X., HUMPHREY, W. R., SHEBUSKI, R. J., and LEVY, R. J., 1997, Formulation and characterization of biodegradable nanoparticles for intravascular local drug delivery. Journal of Controlled Release, 43, 197-212.
  • THANOS, C. G., YIP, K. P., JACOB, Y. S., and MATHIOWITZ, E., 2000, Effects of microsphere composition on uptake in the rabbit jejunum. Proceedings of the International Symposium on Controlled Release of Bioactive Materials, 27, 780-781.
  • ZHU, K. J., JIANG, H. L., Du, X. Y., WANG, J., XU, W. X., and LIU, S. F., 2001, Preparation and characterization of hCG-loaded polylactide or poly(lactide-co-glycolide) microspheres using a modified water-in-oil-in-water (w/o/w) emulsion solvent evaporation technique. Journal of Microencapsulation, 18, 247-260.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.