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Research Article

The effect of solvent removal conditions on performance and release property of protein-loaded microparticles

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Pages 767-773 | Published online: 29 Sep 2008

  • ARSHADY, R., 1991, Preparation of biodegradable microspheres and microcapsules: 2, polylactides and related polyester. Journal of Controlled Release, 17, 1-22.
  • ASANO, M, YOSHIDA, M., FUKUZAKI, H., KUMAKURA, M., MASHIMO, T., YUASA, H., IMAI, K. and YAMANAKA, H., 1990, Effect of crystallinity on the in vivo degradation of poly(ß-propiolactone) prepared by radiation-induced solid polymerization in organic solvent system at low temperature. European Polymerization Journal, 26, 29-33.
  • CRESCENZI, V., MANZINI, G., CALZOLARI, G. and BORRI, C., 1972, Thermodynamics of fusion of poly-ß-propiolactone and e-caprolactone. Comparative analysis of the melting of aliphatic polylactone and polyester chains. European Polymerization Journal, 8, 449-463.
  • HUANG, L. I., 1999, The studies on protein-loaded poly(e-caprolactone) microparticles prepared by solvent evaporation method. MS thesis, Graduate School of Pharmacy, National Taiwan University, Taipei, Taiwan.
  • IMASAKA, K. and NAGAI, T., 1991, Effect of phosphoric acid on the polycondensation of e-caprolactone with d-valerolactone and biodegradation of their copolyester. Makromolecular Chemistry, 192, 1067-1072.
  • IMASAKA, K., NAGAI, T., YOSHIDA, M., FUKUZAKII, H., ASANO, M. and KUMAKURA, M., 1992, Radiation degradation of a new biodegradable copolyester consisting of epsiloncaprolactone and delta-valerolactone prepared by direct polycondensation in the absence of catalysts. Radiation Physical Chemistry, 39, 235-236.
  • IMASAKA, K., YOSHIDA, M., FUKUZAKI, H., ASANO, M., KUMAKURA, M., MASHIMO, T., YAMANAKA, H. and NAGAI, T., 1991, A new biodegradable implant consisting of waxy-type poly(e-caprolactone-co-d-valerolactone) and estrarnustine. International Journal of Pharmaceutics, 68, 87-95.
  • LIN, W. J., 1999, Comparison of thermal characteristics and degradation property of e-caprolactone copolymers. Journal of Biomedical Material Research, 47, 420-423.
  • LIN, W. J. and HUANG, L. I., 2001, Fabrication of porous polyfe-caprolactone) microparticles for protein release. Journal of Microencapsulation, 18, 577-584.
  • MALLAPRAGADA, S. K., PEPPAS, N. A. and COLOMBO, P., 1997, Crystal dissolution-controlled release systems. II. Metronidazole release from semicrystalline poly(vinyl alcohol) systems. Journal of Biomedical Material Research, 36, 125-130.
  • PITT, C. G., Gu, Z. W., INGRAM, P., KIMMEL, G. L., SURLES, J. and SCHINDLER, A., 1981, Aliphatic polyesters II. The degradation of poly(DL-lactide), poly(e-caprolactone) and their copolymers in vivo. Biomaterials, 2, 215-220.
  • VANDAMME, T. F. and GILLARD, J. L., 1993, Poly-e-caprolactone microspheres containing calcitonin preparation, morphology and release properties. Proceedings of the International Symposium on Controlled Release of Bioactive Material, 20, 282-283.
  • YOUAN, B. B. C., BENOIT, M. A., BARAS, B. and GILLARD, J., 1999, Protein-loaded poly(e- caprolactone) microparticles. I. Optimization of the preparation by (water-in-oil)-in water emulsion solvent evaporation. Journal of Microencapsulation, 16, 587-599.

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