53
Views
12
CrossRef citations to date
0
Altmetric
Research Article

Improvement of protein loading and modulation of protein release from poly(lactide-co-glycolide) microspheres by complexation of proteins with polyanions

, , &
Pages 615-624 | Received 22 Oct 2003, Accepted 25 Feb 2004, Published online: 03 Oct 2008

References

  • CROTTS, G. and PARK, T. G., 1997, Stability and release of bovine serum albumin encapsulated within poly(D,L-lactide-co-glycolide) microparticles. Journal of Controlled Release, 44, 123–134.
  • DUBIN, P. L., GAO, J. and MATTISON, K., 1994, Protein purification by selective phase separation with polyelectrolytes. Separation and Purification Methods, 23, 1–16.
  • DUMITRIU, S. and CHORNET, E., 1998, Inclusion and release of proteins from polysaccharide-based polyion complexes. Advances in Drug Delivery Reviews, 31, 223–246.
  • HORA, M. S., RANA, R. S., NUNBERG, H., TICE, T. R., GILLEY, R. M. and HUDSON, M. E., 1990, Release of human serum albumin from poly(lactide-co-glycolide) micro-spheres. Pharmaceutical Research, 7, 1190–1194.
  • JIANG, H. L. and ZHu, K. J., 2001, Polyanion/gelatin complexes as pH-sensitive gels for controlled protein release. Journal of Applied Polymer Science, 80, 1416–1425.
  • JOHANSEN, P., MEN, Y., AUDRAN, R., CORRADIN, G., MERKLE, H. P. and GANDER, B., 1998, Improving stability and release kinetics of microencapsulated tetanus toxoid by co-encapsulation of additives. Pharmaceutical Research, 15, 1103–1110.
  • JOHNSON, 0. L., JAwoRowicz, W., CLELAND, J. L., BAILEY, L., CHARNIS, M., DUENAS, E., Wu, C., SHEPARD, D., MAGIL, S., LAST, T., JONES, A. J. S. and PUTNEY, S. D., 1997, The stabilization and encapsulation of human growth hormone into biodegradable microspheres. Pharmaceutical Research, 14, 730–735.
  • KUDRYASHOVA, E. V., GLADILIN, A. K., VAKUROV, A. V., HEITZ, F., LEVASHOV, A. V. and MAZHAEV, V. V., 1997, Enzyme-polyelectrolyte complexes in water-ehtanol mixtures: negatively charged groups artificially introduced into a-chymotrypsin provide additional activation and stabilization effects. Biotechnology and Bioengineering, 55, 267–277.
  • LEO, E., PECQUET, S., ROJAS, J., COUVREUR, P. and FATTAL, E., 1998, Changing the pH of the external aqueous phase may modulate protein entrapment and delivery from poly(lactide-co-glycolide) microspheres prepared by a w/o/w solvent evaporation method. Journal of Microencapsulation, 15, 421–430.
  • MUNIRUZZAMAN, M., HIJIKATA, T. S., NAGANO, A. and IKADA, Y., 1998, Structural change of basic fibroblast growth factor through gelatin complexation. Polymer Preparation, 39, 247–248.
  • MUNIRUZZAMAN M., TABATA, Y. and IKADA, Y., 1997, Protein interaction with gelatin hydrogels for tissue engineering. Materials Science Forum, 250, 89–96.
  • OGAWA, Y., YAMAMOTO, M., OKADA, H., YASHIKI, T. and SHIMAMOTO, T., 1988, A new technique to efficiently entrap Leuprolide acetate into microcapsules of polylac-tide acid or copoly(lactic/glycolic) acid. Chemical and Pharmaceutical Bulletin, 36, 1095–1103.
  • PARK, T. G., Lu, W. and CROTTS, G., 1995, Importance of the in vitro experimental conditions on protein release kinetics, stability and polymer degradation in protein encapsulated poly(D,L-lactide-co-glycolide) microspheres. Journal of Controlled Release, 33,211–222.
  • PEAN, J.-M., BOURY, F., VENIER-JULIENNE, M.-C., MENEI, P., PROUST, J.-E. and BENOIT, J.-P., 1999, Why dose PEG 400 co-encapsulation improve NGF stability and release from PLGA biodegradable microspheres. Pharmaceutical Research, 16, 1294–1299.
  • PIERCE, B. L. J., GIBSON, T. D. and BUNNEL, P., 1998, Stabilisation of the biological component of biosensors. Special Publication—Royal Society of Chemistry, 167, 54–60.
  • POWELL, M. F., 1996. Drug delivery issues in vaccine development. Pharmaceutical Research, 13, 1777–1785.
  • ROJAS, J., PINTO-ALPHANDARY, H., LEO, E., PECQUET, S., COUVREUR, P., GULIK, A. and FATTAL, E., 1999, A polysorbate-based non-ionic surfactant can modulate loading and release of 13-1actoglobulin entrapped in multiphase poly(DL-lactide-co-glycolide) microspheres. Pharmaceutical Research, 16, 255–260.
  • SCHWENDEMAN, S. P., CARDAMONE, M., KLIBANOV, A. and LANGER, R., 1996, In Microparticulate systems for the delivery of proteins and vaccines, edited by S. Cohen and H. Bernstein (New York: Marcel Dekker), pp. 1–49.
  • TABATA, Y., HIJIKATA, S. and IKADA, Y., 1994, Enhanced vascularization and tissue granulation by basic fibroblast growth factor impregnated in gelatin hydrogels. Journal of Controlled Release, 31, 189–199.
  • TSUBOI, A., Izumi, T., HIRATA, M., XIA, J. L., DUBIN, P. L. and KOKUFUTA, E., 1996, Complexation of proteins with a strong polyanion in an aqueous salt-free system. Langmuir, 12, 6295–6303.
  • VOLKIN, D. B., TSAI, P. K., DABORA, J. M., GRESS, J. 0., BURKE, C. J., LINHARDT, R. J. and MIDDAUGH, C. R., 1993, Physical stabilization of acidic fibroblast growth factor by polyanions. Archives of Biochemistry and Biophysics, 300, 30–41.
  • WANG, N. and Wu, X. S., 1998, A novel approach to stabilization of protein drugs in poly(lactic-co-glycolic acid) microspheres using agarose hydrogel. International Journal of Pharmaceutics, 166, 1–14.
  • WEN, Y.-P. and DUBIN, P. L., 1997, Potentiometric studies of the interaction of bovine serum albumin and poly(dimethyldiallylammonium chloride). Macromolecules, 30, 7856–7861.
  • XIA, J. and DUBIN, P. L., 1994, Protein-polyeelctrolyte complexes. In Macromolecular Complexes in Chemistry and Biology, edited by P. Dubin, J. Bock, R. Davis, D. N. Schulz and C. Thies (Berlin: Springer-Verlag), pp. 247–270.
  • ZHU, G. Z., MALLERY, S. and SCHWENDEMAN, S. P., 2000, Stabilization of pro-teins encapsulated in injectable poly(lactide-co-glycolide). Natural Biotechnology, 18, 52–57.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.