Advanced search
Publication Cover
Journal of Microencapsulation
Micro and Nano Carriers
Volume 21, 2004 - Issue 8
Submit an article Journal homepage
153
Views
12
CrossRef citations to date
0
Altmetric
Research Article

The mechanism of surface-indented protein-loaded PLGA microparticle formation: the effects of salt (NaCl) on the solidification process

J.-L. Chen Graduate Institute of Life Sciences, Tri-Service General Hospital, National Defense Medical Center, National Defense University, Neihu, PO Box 90048–508, Taipei (114), Taiwan; School of Pharmacy, Tri-Service General Hospital, National Defense Medical Center, National Defense University, Neihu, PO Box 90048–508, Taipei (114), Taiwan
,
M.-K. Yeh Department of Clinical Pharmacy, Tri-Service General Hospital, National Defense Medical Center, National Defense University, Neihu, PO Box 90048–508, Taipei (114), Taiwan
&
C.-H. Chiang School of Pharmacy, Tri-Service General Hospital, National Defense Medical Center, National Defense University, Neihu, PO Box 90048–508, Taipei (114), TaiwanCorrespondence[email protected]
Pages 877-888 | Received 28 Apr 2003, Accepted 10 Aug 2004, Published online: 03 Oct 2008

References

  • CHEN, J. L., CHIANG, C. H. and YEH, M. K., 2002, The mechanism of PLA microparticle formation by water-in oil-water solvent evaporation method. Journal of Microencapsulation, 19, 333–346.
  • COOMBES, A. G., YEH, M. K., LAVELLE, E. C. and DAVIS, S. S., 1998, The control of protein release from poly(D,L-lactide co-glycolide) microparticles by variation of the external aqueous phase surfactant in the water-in oil-in water method. Journal of Controlled Release, 52, 311–320.
  • HERRMANN, J. and BUDMEIER, R., 1995, The effect of particle microstructure 011 the somatostatin release from poly(lactide) microspheres prepared by a W/O/W solvent evaporation method. Journal of Controlled Release, 36, 63–71.
  • JIANG, W. and SCHWENDEMAN, S. P., 2001, Stabilization and controlled release of bovine serum albumin encapsulated in poly(D,L-lactide) and poly(ethylene glycol) microsphere blends. Pharmceutical Research, 18, 878–885.
  • PEAN, J. M., VENIER-JULIENNE, M. C., BOURY, F., MENEI, P., DENIZOT, B. and BENOIT, J. P., 1998, NGF release from poly(D,L-lactide-co-glycolide) microspheres. Effect of some formulation parameters on encapsulated NGF stability. Journal of Controlled Release, 56, 175–187.
  • PISTEL, K. F. and KISSEL, T., 2000, Effects of salt addition on the microencapsulation of proteins using w/o/w double emulsion technique. Journal of Microencapsulation, 17, 467–483.
  • THOMASIN, C., MERKLE, H. P. and GANDER, B. A., 1997, Physico-chemical parameters governing protein microencapsulation into biodegradable polyesters by coacerva-tion. Internal Journal of Pharmaceutics, 147, 173–186.
  • UCHIDA, T., YOSHIDA, K., NINOMIYA, A. and GOTO, S., 1995, Optimization of preparative conditions for polylactide (PLA) microspheres containing ovalbumin. Chemical Pharmaceutical Bulletin, 43, 1569–1573.
  • WANG, J. and SCHWENDEMAN, S. P., 1999, Mechanism of solvent evaporation encapsulation process: prediction of solvent evaporation rate. Journal of Pharmaceutical Sciences, 88, 1090–1098.
  • WITSCHI, C. and DOELKER, E., 1998, Influence of the microencapsulation method and peptide loading on poly(lactic acid) and poly(lactic-co-glycolic acid) degradation during in vitro testing. Journal of Controlled Release, 51, 327–341.
  • YEH, M. K., CHEN, J. L. and CHIANG, C. H., 2002a, Vibrio cholerae-loaded poly(DL-lactide co-glycolide) microparticles. Journal of Microencapsulation, 19, 203–212.
  • YEH, M. K., COOMBES, A. G. A., CHEN, J. L. and CHIANG, C. H., 2002c, Japanese Encephalitis virus vaccine formulations using PLA lamellar and PLG microparticles adjuvant. Journal of Microencapsulation, 19, 671–682.
  • YEH, M. K., Liu, Y. T., CHEN, J. L. and CHIANG, C. H., 2002b, Oral immunogenicity of the inactivated Vibrio cholerae whole cell vaccine encapsulated in biodegradable microparticles. Journal of Controlled Release, 82, 237–247.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.