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Research Article

Cationic stearylamine-containing biodegradable microparticles for DNA delivery

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Pages 25-36 | Received 26 Apr 2003, Accepted 19 Jul 2003, Published online: 03 Oct 2008

References

  • CHEN, H. L. R., 1998, Oral particulate delivery: status and future trends. Advanced Drug Delivery Reviews, 34, 339–350.
  • DUPUIS, M., DENIS-MIZE, K., Woo, C., GOLDBECK, C., SELBY, M. J., CHEN, M., OTTEN, G. R., ULMER, J. B., DONNELLY, J. J., OTT, G. and MCDONALD, D. M., 2000, Distribution of DNA vaccines determines their immunogenicity after intramuscular injection in mice. Journal of Immunology, 165, 2850–2858.
  • ERNI, C., SUARD, C., FREITAS, S., DREHER, D., MERKLE, H. P. and WALTER, E., 2002, Evaluation of cationic solid lipid microparticles as synthetic carriers for the targeted delivery of macromolecules to phagocytic antigen-presenting cells. Biomaterials, 23, 4667–4676.
  • EYLES, J. E., BRAMWELL, V. W., WILLIAMSON, E. D. and ALPAR, H. 0., 2001, Microsphere translocation and immunopotentiation in systemic tissues following intranasal administration. Vaccine, 19, 4732–4742.
  • Houx, B. E., MARTIN, R., HOCHHAUS, G. and HUGHES, J. A., 2001, Pharmacokinetics of plasmid DNA in the rat. Pharmaceutical Research, 18, 67–74.
  • VAN DER LUBBEN, I. M., KONINGS, F. A., BORCHARD, G., VERHOEF, J. C. and JUNGINGER, H. E., 2001, In vivo uptake of chitosan microparticles by murine Peyer's patches: visualization studies using confocal laser scanning microscopy and immunohis-tochemistry. Journal of Drug Targeting, 9, 39–47.
  • MAHONEY, M. J. and SALTZMAN, W. M., 2001, Transplantation of brain cells assembled around a programmable synthetic microenvironment. Nature Biotechnology, 19, 934–939.
  • MANUEL, W. S., ZHENG, J. I. and HORNSBY, P. J., 2001, Transfection by polyethyleneimine-coated microspheres. Journal of Drug Targeting, 9, 15–22.
  • NEWMAN, K. D., ELAMANCHILI, P., KWON, G. S. and SAMUEL, J., 2002, Uptake of poly(D,L-lactic-co-glycolic acid) microspheres by antigen-presenting cells in vivo. Journal of Biomedical Materials Research, 60, 480–486.
  • SANDHU, J. S., KEATING, A. and Hozumi, N., 1997, Human gene therapy. Critical Reviews in Biotechnology, 17, 307–326.
  • SINGH, M., BRIONES, M., OTT, G. and O'HAGAN, D., 2000, Cationic microparticles: A potent delivery system for DNA vaccines. Proceedings of the National Academy of Sciences of the USA, 97, 811–816.
  • SINGH, M., OTT, G., KAZZAZ, J., UGOZZOLI, M., BRIONES, M., DONNELLY, J. and O'HAGAN, D. T., 2001a, Cationic microparticles are an effective delivery system for immune stimulatory CpG DNA. Pharmaceutical Research, 18, 1476–1479.
  • SINGH, M., VAJDY, M., GARDNER, J., BRIONES, M. and O'HAGAN, D. T., 2001b, Mucosal immunization with HIV-1 gag DNA on cationic microparticles prolongs gene expression and enhances local and systemic immunity. Vaccine, 20, 594–602.
  • THOMASIN, C., CORRADIN, G., MEN, Y., MERKLE, H. P. and GANDER, B., 1996, Tetanus toxoid and synthetic malaria antigen containing poly(lactide)/poly(lactide-co-glycolide) microspheres: Importance of polymer degradation and antigen release for immune response. Journal of Controlled Release, 41, 131–145.
  • TSENG, W., PURVIS, N. B., HASELTON, F. R. and GIORGIO, T. D., 1996, Cationic liposomal delivery of plasmid to endothelial cells measured by quantitative flow cytometry. Biotechnology & Bioengineering, 50, 548–554.
  • VAJDY, M. and O'HAGAN, D. T., 2001, Microparticles for intranasal immunization. Advanced Drug Delivery Reviews, 51, 127–141.
  • WALTER, E., MOELLING, K., PAVLOVIC, J. and MERKLE, H. P., 1999, Microencapsulation of DNA using poly(DL-lactide-co-glycolide): stability issues and release character-istics. Journal of Controlled Release, 61, 361–374.
  • WALTER, E., DREHER, D., KOK, M., THIELE, L., KIAMA, S. G., GEHR, P. and MERKLE, H. P., 2001, Hydrophilic poly(DL-lactide-co-glycolide) microspheres for the delivery of DNA to human-derived macrophages and dendritic cells. Journal of Controlled Release, 76, 149–168.
  • WALTER, E. and MERKLE, H.P., 2002, Microparticle-mediated transfection of non-phagocytic cells in vitro. Journal of Drug Targeting, 10, 11–21.
  • VON WEIZSACKER, F., 1995, Gene therapy: application possibilities. Schweizerische Rundschau fur Medizin Praxis, 84, 39–42.
  • ZIMMERMAN, I., 1997, Possibilities and limitations of laser light scattering techniques for particle size analysis. In R. H. Muller and W. Mehnert (eds.) Particle and Surface Characterisation Methods (Stuttgart: Medpharm).
  • ZUIDAM, N. J., POSTHUMA, G., DE VRIES, E. T., CROMMELIN, D. J., HENNINK, W. E. and STORM, G., 2000, Effects of physicochemical characteristics of poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes on cellular association and internalization. Journal of Drug Targeting, 8, 51–66.

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