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Journal of Microencapsulation
Micro and Nano Carriers
Volume 21, 2004 - Issue 5
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Research Article

Ca-alginate microspheres encapsulated in chitosan beads

S.-B. Park Department of Chemical Engineering, College of Engineering and Bioproducts Research Center, Yonsei University, Seoul 120-749, South Korea
,
H.-W. Kang Drug Delivery Research, Samyang R&D Center, 63-2 Hwaam-Dong, Yusung-Gu, Teajeon 305-717, South Korea
,
S. Haam Department of Chemical Engineering, College of Engineering and Bioproducts Research Center, Yonsei University, Seoul 120-749, South KoreaCorrespondence[email protected]
,
H.-Y. Park DDS Team, Pharmaceutical & Health Research Institute, Pacific R&D Center, 314-1 Bora-Ri, Kiheung-Eup, Yongin-Si, Kyounggi-Do, 449-900, South Korea
&
W.-S. Kim Department of Chemical Engineering, College of Engineering and Bioproducts Research Center, Yonsei University, Seoul 120-749, South Korea
Pages 485-497 | Received 15 Jul 2003, Accepted 10 Apr 2004, Published online: 03 Oct 2008

References

  • AYDIN, Z. and AKBUGA, J., 1996, Chitosan beads for the delivery of salmon calcitonin: preparation and release characteristics. International Journal of Pharmaceutics, 131, 101–103.
  • DECHO, A. W., 1999, Imaging an alginate polymer gel matrix using atomic force microscopy. Carbohydrate Research, 315, 330–333.
  • GAMZAZADE, A. I. and NASIBOV, S. M., 2002, Fomation and properties of polyelectrolyte complexes of chitosan hydrochloride and sodium dextransulfate. Carbohydrate Polymers, 50, 339–343.
  • GOMBOTZ, W. R. and WEE, S., 1998, Protein release from alginate matrices. Advanced Drug Delivery Reviews, 31, 267–285.
  • HARI, P. R., CHANDY, T., and SHARMA, C. P., 1996, Chitosan/calcium-alginate beads for oral delivery of insulin. Journal of Applied Polymer Science, 59, 1795–1801.
  • HUGUET, M. L. and DELLACHERIE, E., 1996, Calcium alginate beads coated with chitosan: effect of the structure of encapsulated materials on their release. Process Biochemistry, 31, 745–751.
  • HUGUET, M. L., NEUFELD, R. J. and DELLACHERIE, E., 1996, Calcium-alginate beads coated with polycationic polymers: comparison of chitosan and DEAE-dextran. Process Biochemistry, 31, 347–353.
  • ITAYA, T., 2002, Formation of amphiphilic complexes of cationic polyelectrolyte carrying pendant saccharide residue with anionic surfactants. Polymer, 43, 2255–2260.
  • LEE, B. J. and MIN, G. H., 1996, Oral controlled release of melatonin using polymer-reinforced and coated alginate beads. International Journal of Pharmaceutics, 144, 37–46.
  • LEE, K. Y., PARK, W. H. and HA, W. S., 1997, Polyelectrolyte complexes of sodium alginate with chitosan or its derivatives for microcapsules. Journal of Applied Polymer Science, 63, 425–432.
  • MAEDA, H., SASAKI, S., MASHITA, T., NAKAMURA, K., °JIMA, H., GOTAH, T., FUKUDA, T. and YAMANAKA, M., 1995, Dissipative structure in aqueous polymer solutions. Journal of Molecular Liquids, 65, 341–344.
  • MI, F. L., SHYU, S. S., LEE, S. T. and WONG, T. B., 1999, Kinetic study of chitosan-tripolyphosphate complex reaction and acid-resistive properties of the chitosan-tripolyphosphate gel beads prepared by in-liquid curing method. Journal of Polymer Science Part B: Polymer Physics, 37, 1551–1564.
  • MORTIMER, R. J. and ANSON, F. C., 1982, Apparent diffusion coefficients and electron propagation mechanisms in viologen polyelectrolyte coatings containing multiply-charged anions. Journal of Electroanalytical Chemistry, 138, 325–341.
  • MUZZARELLI, R. A. A., 1973, Natural Chelating Polymers: Alginic acid, Chitin and Chitosan (Oxford: Pergamon Press), pp. 144–174.
  • OSTBERG, T. and GRAFFNER, C., 1994, Calcium alginate matrices for oral multiple unit administration: III. Influence of calcium concentration, amount of drug added and alginate characteristics on drug release. International Journal of Pharmaceutic, 111, 271–282.
  • OSTBERG, T., LUND, E. M. and GRAFFNER, C., 1994, Calcium alginate matrices for oral multiple unit administration: IV. Release characteristics in different media. International Journal of Pharmaceutic, 112, 241–248.
  • PARK, S. B., You, J. 0. H. Y., HAAM, S. and KIM, W. S., 2001, A novel pH-sensitive membrane from chitosan-TEOS IPN: preparation and its drug permeation characteristics. Biomaterials, 22, 323–330.
  • SCHWARZ, H. H., LUKA, J. and RICHAU, K., 2003, Surface and permeability properties of membranes from polyelectrolyte complexes and polyelectrolyte surfactant complexes. Journal of Membrane Science, 218, 1–9.
  • SUGAI, S., 1985, Conformations of hydrophobic polyelectrolytes. Advances in Colloid and Interface Science, 24, 247–282.
  • YAMADA, M. and SHIRATORI, S. S., 2000, Smoke sensor using mass controlled layer-by-layer self-assembly of polyelectrolytes films. Sensors and Actuators B: Chemical, 64, 124–127.
  • YAO, K. D., Tu, H., CHENG, F., ZHANG, J. W. and Liu, J., 1997, pH-Sensitivity of the swelling of a chitosan-pectin polyelectrolyte complex. Die Angewandte Makromolekulare Chemie, 245, 63–72.
  • You, J. 0., PARK, S. B., PARK, H. Y., HAAM, S., CHUNG, C. H. and KIM, W. S., 2001, Preparation of regular sized Ca-alginate microspheres using membrane emulsification method. Journal of Microencapsulation, 18, 521–532.

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