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Research Article

Zein microspheres as drug/antigen carriers: A study of their degradation and erosion, in the presence and absence of enzymes

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Pages 303-314 | Received 09 Jun 2005, Accepted 10 Sep 2005, Published online: 08 Oct 2008

References

  • Ahsan F, Rivas IP, Khan MA, Torres AI. Targeting to macrophages: Role of physicochemical properties of particulate carriers—liposomes and microspheres—on the phagocytosis by macrophages. Journal of Controlled Release 2002; 79: 29–40
  • Anon. Wheat gluten, corn gluten and zein: Affirmation of GRAS status. Federal Register 1985; 50: 8997–8999
  • Bean SR, Lookhart GL, Bietz JA. Acetonitrile as a buffer additive for free zone capillary electrophoresis separation and characterization of maize (Zea mays L.) and sorghum (Sorghum bicolor L. Moench) storage proteins. Journal of Agricultural and Food Chemistry 2000; 48: 318–327
  • Demchak RJ, Dybas RA. Photostability of abamectin/zein microspheres. Journal of Agricultural and Food Chemistry 1997; 45: 260–262
  • Dong J, Sun Q, Wang J-Y. Basic study of corn protein, zein, as a biomaterial in tissue engineering, surface morphology and biocompatibility. Biomaterials 2004; 25: 4691–4697
  • Duodo KG, Nunes A, Delgadillo I, Parker ML, Mills ENC, Belton PS, Taylor JRN. Effect of grain structure and cooking on sorghum and maize in vitro protein digestibility. Journal of Cereal Science 2002; 35: 161–174
  • Duodo KG, Taylor JRN, Belton PS, Hamaker BR. Factors affecting sorghum protein digestibility. Journal of Cereal Science 2003; 38: 117–131
  • Esen A. Separation of alcohol-soluble proteins (zeins) from maize into three fractions by differential solubility. Plant Physiology 1986; 80: 623–627
  • Esen A. A proposed nomenclature for the alcohol-soluble proteins (zeins) of maize (Zea mays L.). Journal of Cereal Science 1987; 5: 117–128
  • Fahmy WG, Aufrére J, Graviou D, Demarquilly C, El-Shazly K. Comparison between the mechanism of protein degradation of two cereals by enzymatic and in situ methods, using gel electrophoresis. Animal Feed Science and Technology 1991; 35: 115–130
  • Gianazza E, Viglienghi V, Righetti PG, Salamini F, Soave C. Amino acid composition of zein molecular components. Phytochemistry 1977; 16: 315–317
  • Hurtado-Lopez P, Murdan S. Formulation and characterisation of zein microspheres as delivery vehicles. Journal of Drug Delivery Science and Technology 2005; 15: 267–272
  • Kendall R, Murdan S, Basit A. Modified release microparticles for oral drug delivery. Drug Delivery Technology 2005; 5: 76–80
  • Landry J, Guyon P. Zein of the maize grain 1. Isolation by gel filtration and characterization of monomeric and dimeric species. Biochimie 1984; 66: 451–460
  • Liu X, Sun Q, Wang H, Zhang L, Wang J-Y. Microspheres of corn protein, zein, for an ivermectin drug delivery system. Biomaterials 2005; 26: 109–115
  • Mathiowitz E, Bernstein H, Morrel E, Schwaller K. Method for producing protein microspheres. 1993, US Patent 5,271,961
  • Matsuda Y, Sazuki T, Sato E, Sato M, Koizumi S, Unno K, Kato T, Nakai K. Novel preparation of zein microspheres conjugated with PS-K available for cancer immunotherapy. Chemical and Pharmaceutical Bulletin 1989; 37: 757–759
  • Mauguet MC, Legrand J, Brujes L, Carnelle G, Larre C, Popineau Y. Gliadin matrices for microencapsulation processes by simple coacervation method. Journal of Microencapsulation 2002; 19: 377–384
  • Paulis JW. Disulfide structures of zein proteins from corn endosperm. Cereal Chemistry 1981; 58: 542–546
  • Righetti PG, Bossi A, Oliveri E, Gelfi C. Capillary electrophoresis of peptides and proteins in acidic, isoelectric buffers: Recent developments. Journal of Biochemical and Biophysical Methods 1999; 40: 1–15
  • Righetti PG, Oliveri E, Viotti A. Identification of maize lines via capillary electrophoresis of zeins in isoelectric, acidic buffers. Electrophoresis 1998; 19: 1738–1741
  • Shukla R, Cheryan M. Zein: The industrial protein from corn. Industrial Crops and Products 2001; 13: 171–192
  • Suzuki T, Sato E, Matsuda Y, Tada H, Unno K, Kato T. Preparation of zein microspheres conjugated with antitumor drugs available for selective cancer chemotherapy and development of a simple colorimetric determination of drugs in microspheres. Chemical and Pharmaceutical Bulletin 1989; 37: 1051–1054
  • Swallen LC. Zein, a new industrial protein. Industrial and Engineering Chemistry 1941; 3: 394–398
  • Turner JE, Boundy JA, Dimler RJ. Zein: A heterogeneous protein containing disulfide-linked aggregates. Cereal Chemistry 1985; 42: 452–461
  • Wilson CM. A nomenclature for zein polypeptides based on isoelectric focusing and sodium dodecyl sulfate polyacrylamide gel electrophoresis. Cereal Chemistry 1985; 62: 361–365

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