350
Views
79
CrossRef citations to date
0
Altmetric
Research Article

Influence of surfactants, polymer and doxorubicin loading on the anti-tumour effect of poly(butyl cyanoacrylate) nanoparticles in a rat glioma model

, , , , &
Pages 582-592 | Received 22 Nov 2005, Accepted 15 Jan 2006, Published online: 08 Oct 2008

References

  • Alonso MJ, Sanchez A, Torres D, Seijo B, Vila-Jato JL. Joint effects of monomer and stabilizer concentrations on physico-chemical characteristics of poly(butyl 2-cyanoacrylate) nanoparticles. Journal of Microencapsulation 1990; 7: 517–526
  • Alyautdin RN, Reichel A, Löbenberg R, Ramge P, Kreuter J, Begley DJ. Interaction of poly(butylcyanoacrylate) nanoparticles with the blood–brain barrier in vivo and in vitro. Journal of Drug Targeting 2001; 9: 209–221
  • Ambruosi A, Kholonsky AS, Yamamoto H, Gelperina SE, Begley DJ, Kreuter J. Biodistribution of polysorbate 80-coated doxorubicin-loaded [19C]-poly(butylcyanoacrylate) nanoparticles after intravenous administration to glioblastoma-bearing rats. Journal of Drug Targeting 2006; 14: 103–111
  • Begley DJ. Delivery of therapeutic agents to the central nervous system: The problems and the possibilities. Pharmacology and Therapeutics 2004; 104: 29–45
  • Beijnen JH, Wiese G, Underberg WJ. Aspects of the chemical stability of doxorubicin and seven other anthracyclines in acidic solution. Pharmaceutical Weekblaat Science 1985; 7: 109–116
  • Calvo P, Gouritin B, Chacun H, Desmaele D, D’Angelo J, Noel JP, Georgin D, Fattal E, Andreux JP, Couvreur P. Long-circulating PEGylated polycyanoacrylate nanoparticles as new drug carrier for brain delivery. Pharmaceutical Research 2001; 18: 1157–1166
  • Chen DB, Yang TZ, Lu WL, Zhang Q. In vitro and in vivo study of two types of long-circulating solid lipid nanoparticles containing paclitaxel. Chemical and Pharmaceutical Bulletin, Tokyo 2001; 49: 1444–1447
  • Douglas S, Illum L, Davis SS. Particle size and size distribution of poly(butyl 2-cyano acrylate) nanoparticles. II: Influence of the stabilizer. Journal of Colloid and Interface Science 1985; 103: 154–163
  • Douglas S, Illum L, Davis SS, Kreuter J. Particle size and size distribution of poly(butyl 2-cyano acrylate) nanoparticles. I: Influence of physicochemical factors. Journal of Colloid and Interface Science 1984; 101: 149–158
  • Fang J, Sawa T, Maeda H. Factors and mechanism of ‘EPR’ effect and the enhanced antitumor effects of macromolecular drugs including SMANCS. Advances in Experimental Medical Biology 2003; 519: 29–49
  • Gulyaev AE, Gelperina SE, Skidan IN, Antropov AS, Kivman GY, Kreuter J. Significant transport of doxorubicin into the brain with polysorbate 80-coated nanoparticles. Pharmaceutical Research 1999; 16: 1564–1569
  • Kante B, Couvreur P, Dubois-Krack G, De Meester C, Guiot P, Roland M, Mercier M, Speiser P. Toxicity of polyalkylcyanoacrylate nanoparticles I: Free nanoparticles. Journal of Pharmaceutical Sciences 1982; 71: 786–790
  • Kreuter J. Nanoparticulate systems for brain delivery of drugs. Advances in Drug Delivery Reviews 2001; 47: 65–81
  • Kreuter J. Transport of drugs across the blood–brain barrier by nanoparticles. Current Medical Chemistry—Central Nervous System Agents 2002; 2: 241–249
  • Kreuter J, Petrov VE, Kharkevich DA, Alyautdin RN. Influence of the type of surfactant on the analgesic effects induced by the peptide dalargin after its delivery across the blood–brain barrier using surfactant-coated nanoparticles. Journal of Controlled Release 1997; 49: 81–87
  • Kreuter J, Ramge P, Petrov V, Hamm S, Gelperina SE, Engelhardt B, Alyautdin R, von Briesen H, Begley DJ. Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles. Pharmaceutical Research 2003; 20: 409–16
  • Kreuter J, Shamenkov D, Petrov V, Ramge P, Cychutek K, Koch-Brandt C, Alyautdin RN. Apolipoprotein-mediated transport of nanoparticle-bound drugs across the blood-brain barrier. Journal of Drug Targeting 2002; 10: 317–325
  • Langer K, Seegmüller E, Zimmer A, Kreuter J. Characterization of polybutylcyanoacrylate nanoparticles: I. Quantification of PBCA polymer and dextrans. International Journal of Pharmaceutics 1994; 110: 21–27
  • Lee G, Dallas S, Hong M, Bendayan R. Drug transporters in the central nervous system: Brain barriers and brain parenchyma considerations. Pharmacological Reviews 2001; 53: 569–596
  • Lemarchand C, Gref R, Couvreur P. Polysaccharide-decorated nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics 2004; 58: 327–341
  • Moghimi SM, Hunter AC. Poloxamers and poloxamines in nanoparticle engineering and experimental medicine. Trends in Biotechnology 2000; 18: 412–420
  • Moghimi SM, Hunter AC, Murray JC. Long-circulating and target-specific nanoparticles: Theory to practice. Pharmacological Reviews 2001; 53: 283–318
  • Schlageter KE, Molnar P, Lapin GD, Groothuis DR. Microvessel organization and structure in experimental brain tumors: Microvessel populations with distinctive structural and functional properties. Microvascular Research 1999; 58: 312–328
  • Steiniger SC, Kreuter J, Khalansky AS, Skidan IN, Bobruskin AI, Smirnova ZS, Severin SE, Uhl R, Kock M, Geiger KD, Gelperina SE. Chemotherapy of glioblastoma in rats using doxorubicin-loaded nanoparticles. International Journal of Cancer 2004; 109: 759–767
  • Vajkoczy P, Menger MD. Vascular microenvironment in gliomas. Cancer Treatment Research 2004; 117: 249–262
  • Zara GP, Cavalli R, Bargoni A, Fundaro A, Vighetto D, Gasco MR. Intravenous administration to rabbits of non-stealth and stealth doxorubicin-loaded solid lipid nanoparticles at increasing concentrations of stealth agent: Pharmacokinetics and distribution of doxorubicin in brain and other tissues. Journal of Drug Targeting 2002; 10: 327–335

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.