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Research Article

Effect of process variables on particle size and viability of Bifidobacterium lactis Bb-12 in genipin-gelatin microspheres

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Pages 152-162 | Received 20 Jul 2006, Accepted 15 Sep 2006, Published online: 08 Oct 2008

References

  • Akao T, Kobashi K, Aburada M. Enzymatic studies on the animal and intestinal bacterial metabolism of geniposide. Biological and Pharmaceutical Bulletin 1994; 17: 1573–1576
  • Anonymous. Yoghurt and probiotics. Choice 1992; 32: 32–35
  • Arshady R. Albumin microspheres and microcapsules: Methodology of manufacturing techniques. Journal of Controlled Release 1990; 14: 111–131
  • Chang TM, Prakash S. Artificial cells for bioencapsulation of cells and genetically engineered E. coli for cell therapy, gene therapy, and removal of urea and ammonia. Methods in Molecular Biology 1997; 63: 343–358
  • DeFail AJ, Chu CR, Izzo N, Marra KG. Controlled release of bioactive TGF-β1 from microspheres embedded within biodegradable hydrogels. Biomaterials 2006; 27: 1579–1585
  • Digenis GA, Gold TB, Shah VP. Cross-linking of gelatin capsules and its relevance to their in vitro-in vivo performance. Journal of Pharmaceutical sciences 1994; 83: 915–921
  • Dinarvand R, Mahmoodi S, Farboud E. Effect of process variables on particle size of gelatin microspheres containing lactic acid. Pharmaceutical Development and technology 2004; 9: 291–299
  • Esposito E, Cortesi R, Nastruzzi C. Gelatin microspheres: Influence of preparation parameters and thermal treatment on chemico-physical and biopharmaceutical properties. Biomaterials 1996; 17: 2009–2020
  • Fuller R. Probiotics in man and animals: A review. Journal of Applied Bacteriology 1989; 66: 365–378
  • Jin J, Song M, Hourston DJ. Novel chitosan-based films cross-linked by genipin with improved physical properties. Biomacromolecules 2004; 5: 162–168
  • Kong HJ, Smith MK, Mooney DJ. Designing alginate hydrogels to maintain viability of immobilized cells. Biomaterials 2003; 24: 4023–4029
  • Krasaekoopt W, Bhandari B, Deeth H. Evaluation of encapsulation techniques of probiotics for yoghurt. International Dairy Journal 2003; 13: 3–13
  • Lee YK, Salminen S. The coming to age of probiotics. Trends in Food Science and Technology 1995; 6: 241–245
  • Liang HC, Chang WH, Lin KJ, Sung HW. Genipin-cross-linked gelatin microspheres as a drug carrier for intramuscular administration: In vitro and in vivo studies. Journal of Biomedical Materials Research Part A 2002; 65A: 271–282
  • Narayani R, Rao PK. pH-Responsive gelatin microspheres for oral delivery of anticancer drug methotrexate. Journal of Applied Polymer Science 1995; 58: 1761–1769
  • Prakash S, Jones ML. Artificial cell therapy: New strategies for the therapeutic delivery of live bacteria. Journal of Biomedicine and Biotechnology 2005; 1: 44–56
  • Robinson RK. Survival of L. acidophilus in fermented products. Suid Afikanese Tydskrif Vir Suiwelkunde 1987; 19: 25–27
  • Scardi V. Immobilization of enzymes and microbial cells in gelatin. Methods in Enzymology 1987; 135: 293–299
  • Simulated Gastric Fluid. The National Formulary 18 Board of Trustees. United States Pharmacopeial Convention, Rockville, MD 2000
  • Sung HW, Huang DM, Chang WH, Huang RN, Hsu JC. Evaluation of gelatin hydrogel cross-linked with various cross-linking agents as bioadhesives: In vitro study. Journal of Biomedical Materials Research 1999; 46: 520–530
  • Touyama R, Takeda Y, Inoue K, Kawamura I, Yatsuzuka M, Ikumoto T, Shingu T, Yokoi T, Inouye H. Studies on the blue pigments produced from genipin and methylamine I Structures of the brownish-red pigments, intermediates leading to the blue pigments. Chemical and Pharmaceutical Bulletin 1994; 42: 668–673
  • Truelstrup Hansen L, Allan-Wojtas PM, Jin Y-L, Paulson AT. Survival of Ca-alginate microencapsulated Bifidobacterium spp in milk and simulated gastrointestinal conditions. Food Microbiology 2002; 19: 35–45
  • Tsai CC, Huang RN, Sung HC, Liang HC. In vitro evaluation of the genotoxicity of a naturally occurring cross-linking reagent for biological tissue fixation. Journal of Biomedical Materials Research 2000; 52: 58–65
  • Ugwoke MI, Kinget R. Influence of processing variables on the properties of gelatin microspheres prepared by the emulsification solvent extraction technique. Journal of Microencapsulation 1998; 15: 273–281
  • Vandelli MA, Rivasi F, Guerra P, Forni F, Arletti R. Gelatin microspheres cross-linked with D,L-glyceraldehyde as a potential drug delivery system: Preparation, characterization, in vitro and in vivo studies. International Journal of Pharmaceutics 2001; 215: 175–184
  • Zhang CY, Parton LE, Ye CP, Krauss S, Shen R, Lin CT, Porco JA, Lowell BB. Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced β-cell dysfunction in isolated pancreatic islets. Cell Metabolism 2006; 3: 417–427

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