861
Views
116
CrossRef citations to date
0
Altmetric
Research Article

Electrostatic micro- and nanoencapsulation and electroemulsification: A brief review

Pages 443-468 | Received 10 Apr 2007, Accepted 10 Mar 2008, Published online: 23 Apr 2008

References

  • Abu-Ali J, Barringer SA. Method for electrostatic atomization of emulsions in an EHD system. J Electrostatics 2005; 63: 361–369
  • Almekinders JC, Jones C. Multiple jet electrohydrodynamic spraying and applications. J Aerosol Sci 1999; 30: 969–971
  • Amsden BG, Goosen MFA. An examination of factors affecting the size, distribution and release characteristics of polymer microbeads made using electrostatics. J Contr Rel 1997; 43: 183–196
  • Bailey AG. The theory and practice of electrostatic spraying. Atomiz Spray Techn 1986; 2: 95–134
  • Bailey AG. Electrostatic spraying of liquids. New York; Michelson: Adam Hilger; Bristol, New York: J., Bailey 1988, Wiley & Sons
  • Balachandran W, Jaworek A, Krupa A, Kulon J, Lackowski M. Efficiency of smoke removal by charged water droplets. J Electrostatics 2003; 58: 209–220
  • Balachandran W, Krupa A, Machowski W, Jaworek A. Smoke precipitation by charged water aerosols. J Electrostatics 2001; 51–52: 193–199
  • Balachandran W, Machowski W, Ahmad CN. Electrostatic atomization of conducting liquids using ac superimposed on dc fields. IEEE Trans Ind Appl 1994; 30: 850–855
  • Barrero A, Lopez-Herrera JM, Boucard A, Loscertales IG, Marquez M. Steady cone-jet electrosprays in liquid insulator baths. J Colloid Interface Sci 2004; 272: 104–108
  • Barrero A, Loscertales IG. Micro- and nanoparticles via capillary flows. Annu Rev Fluid Mech 2007; 39: 89–106
  • Bocanegra R, Galan D, Marquez M, Loscertales IG, Barrero A. Multiple electrosprays emitted from an array of holes. J Aerosol Sci 2005a; 36: 1387–1399
  • Bocanegra R, Gaonkar AG, Barrero A, Loscertales IG, Pechack D, Marquez M. Production of cocoa butter microcapsules using an electrospray process. J Food Sci 2005b; 70: E492–E497
  • Bollini R, Sample SB, Seigal SD, Boarman JW. Production of monodisperse charged metal particles by harmonic electrical spraying. J Coll Interface Sci 1975; 51: 272–277
  • Borra JP, Camelot D, Marijnissen JCM, Scarlet B. A new production process of powders with defined properties by electrohydrodynamic atomization of liquids and post-production electrical mixing. J Electrostatics 1997; 40&41: 633–638
  • Borra JP, Ehouarn P, Boulaud D. Electrohydrodynamic atomisation of water stabilised by glow discharge—operating range and droplet properties. J Aerosol Sci 2004; 35: 1313–1332
  • Brandenberger H, Nüssli D, Piëch V, Widmer F. Monodisperse particle production: A method to prevent drop coalescence using electrostatic forces. J Electrostatics 1999; 45: 227–238
  • Brandenberger H, Widmer F. Immobilization of highly concentrated cell suspensions using the laminar jet breakup technique. Biotechnol Prog 1999; 15: 366–372
  • Brown RC. Tutorial review: Simultaneous measurement of particle size and particle charge. J Aerosol Sci 1997; 28: 1373–1391
  • Buchko ChJ, Chen LC, Shen Y, Martin DC. Processing and microstructural characterization of porous biocompatible protein polymer thin films. Polymer 1999; 40: 7397–7407
  • Capek I. Degradation of kinetically-stable o/w emulsions. Adv Colloid Interface Sci 2004; 107: 125–155
  • Challis RE, Povey MJW, Mather ML, Holmes AK. Ultrasound techniques for characterizing colloidal dispersions. Rep Prog Phys 2005; 68: 1541–1637
  • Cherney LT. Structure of Taylor cone-jets: Limit of low flow rates. J Fluid Mech 1999; 378: 167–196
  • Chew SY, Wen J, Yim EKF, Leong KW. Sustained release of proteins from electrospun biodegradable fibers. Biomacromolecules 2005; 6: 2017–2024
  • Ciach T. Particle production for drug delivery. J Aerosol Sci 2004; 35(Suppl. 1)S433–S434
  • Ciach T. Microencapsulation of drugs by electro-hydro-dynamic atomization. Int J Pharm 2006; 324: 51–55
  • Ciach T. Application of electro-hydro-dynamic atomization in drug delivery. J Drug Deliv Sci Tech 2008; 17: 367–375
  • Ciach T, Wang J, Marijnissen J. Production of protein microparticles by electro-hydro-dynamic atomization. J Aerosol Sci 2001; 32: S1001–S1002
  • Cloupeau M, Prunet-Foch B. Electrostatic spraying of liquids. Main functioning modes. J Electrostatics 1990; 25: 165–184
  • Cloupeau M, Prunet-Foch B. Electrohydrodynamic spraying functioning modes, a critical review. J Aerosol Sci 1994; 25: 1121–1136
  • De S, Pritchett M, Mazumder MK, Yurteri CU, Egorov O. Electrostatic microencapsulation technique for producing composite particles. Part Sci Techn 2002; 20: 169–185
  • Demir MM, Yilgor I, Yilgor E, Erman B. Electrospinning of polyurethane fibers. Polymer 2002; 43: 3303–3309
  • Ding L, Lee T, Wang ChH. Fabrication of monodispersed Taxol-loaded particles using electrohydrodynamic atomization. J Contr Rel 2005; 102: 395–413
  • Dos Santos IR, Richard J, Pech B, Thies C, Benoit JP. Microencapsulation of protein particles within lipids using a novel supercritical fluid process. Int J Pharm 2002; 242: 69–78
  • Doshi J, Reneker DH. Electrospinning process and applications of electrospun fibers. J Electrostatics 1995; 35: 151–160
  • Doyle A, Moffett DR, Vonnegut B. Behavior of evaporating electrically charged droplets. J Coll Sci 1964; 19: 136–143
  • Fages J, Lochard H, Letourneau J-J, Sauceau M, Rodier E. Particle generation for pharmaceutical applications using supercritical fluid technology. Powder Techn 2004; 141: 219–226
  • Farook U, Stride E, Edirisinghe MJ, Moaleji R. Microbubbling by co-axial electrohydrodynamic atomization. Med Bio Eng Comput 2007a; 45: 781–789
  • Farook U, Zhang HB, Edirisinghe MJ, Stride E, Saffari N. Preparation of microbubble suspensions by co-axial electrohydrodynamic atomization. Med Eng Phys 2007b; 29: 749–754
  • Fernandez de la Mora J. The fluid dynamics of Taylor cones. Annu Rev Fluid Mech 2007; 39: 217–243
  • Fernandez de la Mora J, Loscertales IG. The current emitted by highly conducting Taylor cones. J Fluid Mech 1994; 260: 155–184
  • Fery A, Dubreuil F, Mohwald H. Mechanics of artificial microcapsules. N J Phys 2004; 6: 1–13
  • Fillmore GL, VanLokeren DC. A multinozzle drop generator which produces uniform breakup of continuous jets. IEEE Trans Ind Appl 1984; 20: 289–292
  • Flagan RC. History of electrical aerosol measurements. Aerosol Sci Techn 1998; 28: 301–380
  • Gañan-Calvo AM. On the theory of electrohydrodynamically driven capillary jets. J Fluid Mech 1997; 335: 165–188
  • Gañan-Calvo AM. Generation of steady liquid microthreads and micron-sized monodisperse sprays in gas streams. Phys Rev Lett 1998; 80: 285–288
  • Gañan-Calvo AM. The surface charge in electrospraying: Its nature and its universal scaling laws. J Aerosol Sci 1999a; 30: 863–872
  • Gañan-Calvo AM. New microfluidic technologies to generate respirable aerosols for medical applications. J Aerosol Sci 1999b; 30(Suppl. 1)5541–5542
  • Gañan-Calvo AM, Davila J, Barrero A. Current and droplet size in the electrospraying of liquids. Scaling laws. J Aerosol Sci 1997; 28: 249–275
  • Garti N. What can nature offer from an emulsifier point of view: Trends and progress?. Coll Surf A: Phys Chem Eng Aspects 1999; 152: 125–146
  • Gneist G, Bart HJ. Droplet formation in liquid/liquid systems using high frequency AC fields. DACHEMA/GVC Working Party ‘Extraction’. Bremen. 2000, 7–8 September 2000
  • Gomez A. The electrospray and its application to targeted drug inhalation. Resp Care 2002; 47: 1419–1433
  • Gomez A, Bingham D, Juan de L, Tang K. Production of protein nanoparticles by electrospray drying. J Aerosol Sci 1998; 29: 561–574
  • Gomez A, Tang K. Charge and fission of droplets in electrostatic sprays. Phys Fluids 1994; 6: 404–414
  • Gouin S. Microencapsulation: Industrial appraisal of existing technologies and trends. Trends Food Sci Technol 2004; 15: 330–347
  • Grace JM, Marijnissen JCM. A review of liquid atomization by electrical means. J Aerosol Sci 1994; 25: 1005–1019
  • Grigor'ev AI, Shir'aeva SO. Mechanism of electrostatic polydispersion of liquid. J Phys D: Appl Phys 1990; 23: 1361–1370
  • Guzey D, McClements DJ. Formation, stability and properties of multilayer emulsions for application in the food industry. Adv Colloid Interface Sci 2006; 128–130: 227–248
  • Hartman RPA, Brunner DJ, Camelot DMA, Marijnissen JCM, Scarlett B. Jet break-up in electrohydrodynamic atomization in the cone-jet mode. J Aerosol Sci 2000; 31: 65–95
  • Hayati I, Bailey AI, Tadros ThF. Investigations into the mechanisms of electrohydrodynamic spraying of liquids. Pt.I. Effect of electric field and the environment on pendant drop and factors affecting the formation of stable jets and atomization. J Coll Interface Sci 1987a; 117: 205–221
  • Hayati I, Bailey AI, Tadros ThF. Investigations into the mechanisms of electrohydrodynamic spraying of liquids. Pt.II. Mechanism of stable jet formation and electrical forces acting on a liquid cone. J Coll Interface Sci 1987b; 117: 222–230
  • Hengelmolen R, Vincent B, Hassall G. Emulsions from aerosol sprays. J Colloid Interf Sci 1997; 196: 12–22
  • Herricks TE, Kim S-H, Kim J, Li D, Kwak JH, Grate JW, Kim SH, Xia Y. Direct fabrication of enzyme-carrying polymer nanofibers by electrospinning. J Mater Chem 2005; 15: 3241–3245
  • Hirech K, Payan S, Carnelle G, Brujes L, Legrand J. Microencapsulation of an insecticide by interfacial polymerisation. Powder Technol 2003; 130: 324–330
  • Hohman MM, Shin M, Rutledge G, Brenner MP. Electrospinning and electrically forced jets. I. Stability theory. Phys Fluids 2001a; 13: 2201–2220
  • Hohman MM, Shin M, Rutledge G, Brenner MP. Electrospinning and electrically forced jets. II. Applications. Phys Fluids 2001b; 13: 2221–2236
  • Hughes JF, Pavey ID. Electrostatic emulsification. J Electrostatics 1981; 10: 45–55
  • Hughes JF, Roberts JMC. Electrostatic emulsification of domestic and personal care products. Int J Cosmetic Sci 1984; 6: 103–113
  • Jafari SM, He Y, Bhandari B. Nano-emulsion production by sonication and microfluidization—a comparison. Int J Food Prop 2006; 9: 475–485
  • Jafari SM, He X, Bhandari B. Effectiveness of encapsulating biopolymers to produce sub-micron emulsions by high energy emulsification techniques. Food Res Int 2007; 40: 862–873
  • Jaworek A. Electrospray droplet sources for thin film deposition. A review. J Mater Sci 2007a; 42: 266–297
  • Jaworek A. Micro- and nanoparticle production by electrospraying. A review. Powder Technol 2007b; 176: 18–35
  • Jaworek A, Balachandran W, Krupa A, Kulon J, Machowski W. Electrohydrodynamic atomization of viscous liquids. Inst Phys Conf Ser No.178 2003; 181–186
  • Jaworek A, Balachandran W, Lackowski M, Kulon J, Krupa A. Multi-nozzle electrospray system for gas cleaning processes. J Electrostatics 2006; 64: 194–202
  • Jaworek A, Czech T, Rajch E, Lackowski M. Spectroscopic studies of electric discharges in electrospraying. J Electrostatics 2005; 63: 635–641
  • Jaworek A, Krupa A. Generation and characteristics of the precession mode of EHD spraying. J Aerosol Sci 1996; 27: 75–82
  • Jaworek A, Krupa A. Studies of the corona discharge in ehd spraying. J Electrostatics 1997; 40–41: 173–178
  • Jaworek A, Krupa A. Jet and drop formation in electrohydrodynamic spraying of liquids. A systematic approach. Exp Fluids 1999a; 27: 43–52
  • Jaworek A, Krupa A. Classification of the modes of EHD spraying. J Aerosol Sci 1999b; 30: 873–893
  • Jaworek A, Machowski W, Krupa A, Balachandran W. Viscosity effect on EHD spraying using AC superimposed on DC Electric Field. IEEE Ind Appl Soc Annual Meeting. Rome 2000; 770–776, 8–12 October 2000
  • Jayasinghe SN, Edirisinghe MJ. A novel method of forming open cell ceramic foam. J Porous Mat 2002; 9: 265–273
  • Jayasinghe SN, Townsend-Nicholson A. Stable electric-field driven cone-jetting of concentrated biosuspensions. Lab Chip 2006; 6: 1086–1090
  • Jiang H, Hu Y, Li Y, Zhao P, Zhu K, Chen W. A facile technique to prepare biodegradable coaxial electrospun nanofibers for controlled release of bioactive agents. J Contr Rel 2005; 108: 237–243
  • Joffre GH, Cloupeau M. Characteristic forms of electrified menisci emitting charges. J Electrostatics 1986; 18: 147–161
  • Jono K, Ichikawa H, Miyamoto M, Fukumori Y. A review of particulate design for pharmaceutical powders and their production by spouted bed coating. Powder Technol 2000; 113: 269–277
  • Joscelyne SM, Trägårdh G. Membrane emulsification—a literature review. J Membr Sci 2000; 169: 107–117
  • Juraschek R, Röllgen FW. Pulsation phenomena during electrospray ionization. Int J Mass Spectrom Ion Proc 1998; 177: 1–15
  • Kenawy ER, Bowlin GL, Mansfield K, Layman J, Simpson DG, Sanders EH, Wnek GE. Release of tetracycline hydrochloride from electrospun poly(ethylene-co-vinylacetate), poly(lactic acid), and a blend. J Contr Rel 2002; 81: 57–64
  • Kim H, Luo D, Link D, Weitz DA, Marquez M, Cheng Z. Controlled production of emulsion drops using an electric field in a flow-focusing microfluidic device. Appl Phys Lett 2007; 91, Paper No. 133106
  • Kobayashi I, Uemura K, Nakajima M. Formulation of monodisperse emulsions using submicron-channel arrays. Colloids Surf A: Physicochem Eng Aspects 2007; 296: 285–289
  • Kowalewski TA, Błoński S, Barral S. Experiments and modelling of electrospinning process. Bull Polish Acad Sci, Techn Sci 2005; 53: 385–394
  • Langer G, Yamate G. Encapsulation of liquid and solid aerosol particles to form dry powders. J Coll Interface Sci 1969; 29: 450–455
  • Law SE. Agricultural electrostatic spray application: A review of significant research and development during the 20th century. J Electrostatics 2001; 51–52: 25–42
  • Law SE, Cooper SC. Depositional characteristics of charged and uncharged droplets applied by an orchard air carrier sprayer. Trans ASAE 1988; 31: 984–989
  • Law SE, Cooper SC, Law WB (1999) Bipolar spray charging for enhanced deposition onto nonconductive and electrically isolated targets. Inst Phys Conf Ser No. 163; 10th Int Conf Electrostatics ‘99. 28–31 March, 1999. Cambridge, 243–248
  • Lee KH, Kim HY, Khil MS, Ra YM, Lee DR. Characterization of nano-structured poly(1-caprolactone) nonwoven mats via electrospinning. Polymer 2003; 44: 1287–1294
  • Lewińska D, Bukowski J, Kinasiewicz A, Weryński A. Electrostatic microencapsulation of hepatocytes using an impulsed voltage droplet generator. ESAO Conference Paper. 2006
  • Lewińska D, Rosiński S, Weryński A. Influence of process conditions during impulsed electrostatic droplet formation on size distribution of hydrogel beads. Artif Cells Blood Sub Biotechnol 2004; 32: 41–53
  • Liao IC, Chew SY, Leong KW. Aligned core-shell nanofibers delivering bioactive proteins. Nanomedicine 2006; 1: 465–471
  • Lopez-Herrera JM, Barrero A, Lopez A, Loscertales IG, Marquez M. Coaxial jets generated from electrified Taylor cones. Scaling laws. J Aerosol Sci 2003; 34: 535–552
  • Loscertales IG, Barrero A, Guerrero I, Cortijo R, Marquez M, Gañan-Calvo AM. Micro/nano encapsulation via electrified coaxial liquid jets. Science 2002; 295: 1695–1698
  • Luu YK, Kim K, Hsiao BS, Chu B, Hadjiargyrou M. Development of a nanostructured DNA delivery scaffold via electrospinning of PLGA and PLA–PEG block copolymers. J Contr Rel 2003; 89: 341–353
  • Marginean I, Kelly RT, Page JS, Tang K, Smith RD. Electrospray characteristic curves: In pursuit of improved performance in the nanoflow regime. Anal Chem 2007a; 79: 8030–8036
  • Marginean I, Nemes P, Vertes A. Order-chaos-order transitions in electrosprays: The electrified dripping faucet. Phys Rev Lett 2006; 97, Paper No. 064502
  • Marginean I, Nemes P, Vertes A. Astable regime in electrosprays. Phys Rev E 2007b; 76, Paper No. 026320
  • Marginean I, Parvin L, Heffernan L, Vertes A. Flexing the electrified meniscus: The birth of a jet in electrosprays. Anal Chem 2004; 76: 4202–4207
  • Marin AG, Loscertales IG, Marquez M, Barrero A. Simple and double emulsions via coaxial jet electrosprays. Phys Rev Lett 2007; 98, Paper No. 014502
  • Meesters GMH, Vercoulen PHW, Marijnissen JCM, Scarlett B. Generation of micron-sized droplets from the Taylor cone. J Aerosol Sci 1992; 23: 37–49
  • Mei F, Chen DR. Investigation of compound jet electrospray: Particle encapsulation. Phys Fluids 2007; 19, paper No. 103303
  • Mestel AJ. Electrohydrodynamic stability of a highly viscous jet. J Fluid Mech 1996; 312: 311–326
  • Michelson D. Electrostatic atomization. IOP Publishing, Bailey: New York; Michelson: Adam Hilger; Bristol, New York 1990
  • Muschiolik G. Multiple emulsions for food use. Curr Opin Colloid Interface Sci 2007; 12: 213–220
  • Nakano M, Takashima K, Katsura Sh, Mizuno A. Development of contactless emulsification method using electrostatic phenomena for biological application. J Electrostatics 2008; 66: 45–50
  • Nawab MA, Mason SG. The preparation of uniform emulsions by electrical dispersion. J Coll Sci 1958; 13: 179–187
  • Nelson G. Application of microencapsulation in textiles. Int J Pharm 2002; 242: 55–62
  • Orive G, Gascon AR, Hernandez RM, Igartua M, Pedraz JL. Cell microencapsulation technology for biomedical purposes: Novel insights and challenges. Trends Pharm Sci 2003; 24: 207–210
  • Orive G, Hernandez RM, Gascon AR, Calafiore R, Chang ThMS, de Vos P, Hortelano G, Hunkeler D, Lacik I, Pedraz JL. History, challenges and perspectives of cell microencapsulation. Trends Biotech 2004; 22: 87–92
  • Paine MD, Alexander MS, Stark JPW. Nozzle and liquid effects on the spray modes in nanoelectrospray. J Coll Interface Sci 2007; 305: 111–123
  • Pareta R, Edirisinghe MJ. A novel method for the preparation of biodegradable microspheres for protein drug delivery. J. R. Soc. Interface 2006; 3: 573–582
  • Pareta R, Brindley A, Edirisinghe MJ, Jayasinghe SN, Luklinska ZB. Electrohydrodynamic atomization of protein (bovine serum albumin). J Mater Sci: Mater Med 2005; 16: 919–925
  • Parvin L, Galicia MC, Gauntt JM, Carney LM, Nguyen AB, Park Y, Heffernan L, Vertes A. Electrospray diagnostics by Fourier analysis of current oscillations and fast imaging. Anal Chem 2005; 77: 3908–3915
  • Poncelet D, Babak VG, Neufeld RJ, Goosen MFA, Bugarski B. Theory of electrostatic dispersion of polymer solutions in the production of microgel beads containing biocatalyst. Adv Coll Interface Sci 1999; 79: 213–228
  • Poncelet D, Bugarski B, Amsden BG, Zhu J, Neufeld R, Goosen MFA. A parallel plate electrostatic droplet generator: Parameters affecting microbead size. Appl Microbiol Biotechnol 1994; 42: 251–255
  • Rayleigh FRS. On the equilibrium of liquid conducting masses charged with electricity. Phil Mag 1882; 14: 184–186
  • Regele JD, Papac MJ, Rickard MJA, Dunn-Rankin D. Effects of capillary spacing on EHD spraying from an array of cone jets. J Aerosol Sci 2002; 32: 1471–1479
  • Sakai T, Sadakata M, Sato M, Kimura K. Production of uniformly sized dual concentric droplets from coaxial smooth jet under applied AC electric field. Atomiz Sprays 1991; 1: 171–185
  • Salalha W, Kuhn J, Dror Y, Zussman E. Encapsulation of bacteria and viruses in electrospun nanofibres. Nanotechnology 2006; 17: 4675–4681
  • Salata OV. Tools of nanotechnology: Electrospray. Curr Nanosci 2005; 1: 25–33
  • Sample SB, Bollini R. Production of liquid aerosols by harmonic electrical spraying. J Coll Interface Sci 1972; 41: 185–193
  • Sanguansri P, Augustin MA. Nanoscale materials development—a food industry perspective. Trends Food Sci Techn 2006; 17: 547–556
  • Sato M. The production of essentially uniform-sized liquid droplets in gaseous or immiscible liquid media under applied ac potential. J Electrostatics 1984; 15: 237–247
  • Sato M. Formation of uniformly sized liquid droplets using spinning disk under applied electrostatic field. IEEE Trans Ind Appl 1991; 27: 316–322
  • Sato M, Hatori T, Saito M. Experimental investigation of droplet formation mechanisms by electrostatic dispersion in a liquid-liquid system. IEEE Trans Ind Appl 1997; 33: 1527–1534
  • Sato M, Kato S, Saito M. Production of oil/water type uniformly sized droplets using a convergent AC electric field. IEEE Trans Ind Appl 1996a; 32: 138–145
  • Sato M, Kudo N, Saito M (1996b) Surface tension reduction of liquid by applied electric field using vibrating jet method. IEEE Ind Appl Soc Annual Meeting. 5–10 October, 1996. San Diego
  • Sato M, Kudo N, Saito M. Surface tension reduction of liquid by applied electric field using vibrating jet method. IEEE Trans Ind Appl 1998; 34: 294–300
  • Sato M, Miyazaki H, Sadakata M, Sakaki T (1988) Production of uniformly sized liquid droplets under applied AC field by means of rotating multi-nozzle system. 4th Int Conf Liquid Atomization and Spray Systems. 22–24 August, 1988. SendaiJapan, 161–165
  • Sato M, Takahashi H, Awazu M, Ohshima T. Production of ultra-uniformly-sized silica particles by applying ac superimposed on dc voltage. J Electrostatics 1999; 46: 171–176
  • Schroeder V, Schubert H. Production of emulsions using microporous, ceramic membranes. Coll Surf A: Physicochem Eng Asp 1999; 152: 103–109
  • Schultze K. Das Verhalten verschiedener Flüssigkeiten bei der Elektrostatischen Zerstaubung. Z Angewandte Physik 1961; 13: 11–16
  • Shiryaeva SO, Grigorev AI. The semiphenomenological classification of the modes of electrostatic dispersion of liquids. J Electrostatics 1995; 34: 51–59
  • Song T, Zhang Y, Zhou T, Lim ChT, Ramakrishna S, Liu B. Encapsulation of self-assembled FePt magnetic nanoparticles in PCL nanofibers by coaxial electrospinning. Chem Phys Lett 2005; 415: 317–322
  • Spernath A, Aserin A. Microemulsions as carriers for drugs and nutraceuticals. Adv Colloid Interface Sci 2006; 128–130: 47–64
  • Srivastava Y, Loscertales I, Marquez M, Thorsen T. Electrospinning of hollow and core/sheath nanofibers using a microfluidic manifold. Microfluid Nanofluid 2008; 4: 245–250
  • Suvorov VG, Litvinov EA. Dynamic Taylor cone formation on liquid metal surface: Numerical modelling. J Phys D: Appl Phys 2000; 33: 1245–1251
  • Sze Tu L, Dehghani F, Foster NR. Micronisation and microencapsulation of pharmaceuticals using a carbon dioxide antisolvent. Powder Technol 2002; 126: 134–149
  • Tadros T, Izquierdo P, Esquena J, Solans C. Formation and stability of nano-emulsions. Adv Coll Interface Sci 2004; 108–109: 303–318
  • Tatemoto Y, Ishikawa R, Takeuchi M, Takeshita T, Noda K, Okazaki T. An electrospray method using a multi-capillary nozzle emitter. Chem Eng Technol 2007; 30: 1274–1279
  • Taylor GFRS. Disintegration of water drops in an electric field. Proc R Soc 1964; A280: 383–397
  • Taylor GFRS, van Dyke MD. Electrically driven jets. Proc R Soc 1969; A313: 453–475
  • Tiarks F, Landfester K, Antonietti M. Preparation of polymeric nanocapsules by miniemulsion polymerization. Langmuir 2001; 17: 908–918
  • Townsend-Nicholson A, Jayasinghe SN. Cell electrospinning: A unique biotechnique for encapsulating living organisms for generating active biological microthreads/scaffolds. Biomacromolecules 2006; 7: 3364–3369
  • Uematsu I, Matsumoto H, Morota K, Minagawa M, Tanioka A, Yamagata Y, Inoue K. Surface morphology and biological activity of protein thin films produced by electrospray deposition. J Colloid Interface Sci 2004; 269: 336–340
  • Umbanhowar PB, Prasad V, Weitz DA. Monodisperse emulsion generation via drop break off in a coflowing stream. Langmuir 2000; 16: 347–351
  • Van Berkel GJ, Kertesz V. Using the electrochemistry of the electrospray ion source. Anal Chem 2007; 79: 5510–5520
  • Verreck G, Chun I, Peeters J, Rosenblatt J, Brewster ME. Preparation and characterization of nanofibers containing amorphous drug dispersions generated by electrostatic spinning. Pharm Res 2003a; 20: 810–817
  • Verreck G, Chun I, Rosenblatt J, Peeters J, Van Dijck A, Mensch J, Noppe M, Brewster ME. Incorporation of drugs in an amorphous state into electrospun nanofibers composed of a water-insoluble, nonbiodegradable polymer. J Contr Rel 2003b; 92: 349–360
  • Vonnegut B, Neubauer RL. Production of monodisperse liquid particles by electrical atomization. J Coll Sci 1952; 7: 616–622
  • Wachtel RE, LaMer VK. The preparation and size distribution of some monodisperse emulsions. J Coll Sci 1962; 17: 531–564
  • Wang Y, Dave RN, Pfeffer R. Polymer coating/encapsulation of nanoparticles using a supercritical anti-solvent process. J Supercritical Fluids 2004; 28: 85–99
  • Watanabe A, Higashitsuji K, Nishizawa K. Studies of electrocapillary emulsification. J Coll Interface Sci 1978; 64: 278–289
  • Watanabe H, Matsuyama T, Yamamoto H. Preparation of immobilized enzyme gel particles using an electrostatic atomization technique. Biochem Eng J 2001; 8: 171–174
  • Xie J, Lim LK, Phua Y, Hua J, Wang Ch-W. Electrohydrodynamic atomization for biodegradable polymeric particle production. J Coll Interface Sci 2006a; 302: 103–112
  • Xie J, Marijnissen JCM, Wang Ch-H. Microparticles developed by electrohydrodynamic atomization for the local delivery of anticancer drug to treat C6 glioma in vitro. Biomaterials 2006b; 27: 3321–3332
  • Xie J, Ng WJ, Lee LY, Wang Ch-H. Encapsulation of protein drugs in biodegradable microparticles by co-axial electrospray. J Coll Interface Sci 2008; 317: 469–476
  • Xie J, Wang Ch-H. Encapsulation of proteins in biodegradable polymeric microparticles using electrospray in the Taylor cone-jet mode. Biotech Bioeng 2007a; 97: 1278–1290
  • Xie J, Wang Ch-H. Electrospray in the dripping mode for cell microencapsulation. J Coll Interface Sci 2007b; 312: 247–255
  • Xu Y, Hanna M. Electrospray encapsulation of water-soluble protein with polylactide. Effects of formulations on morphology, encapsulation efficiency and release profile of particles. Int J Pharm 2006; 320: 30–36
  • Xu YX, Hanna M. Electrosprayed bovine serum albumin-loaded tripolyphosphate cross-linked chitosan capsules: Synthesis and characterization. J Microencapsulation 2007; 24: 143–151
  • Xu Y, Skotak M, Hanna M. Electrospray encapsulation of water-soluble protein with polylactide. I. Effects of formulations and process on morphology and particle size. J Microencapsulation 2006; 23: 69–78
  • Yarin AL, Koombhongse S, Reneker DH. Bending instability in electrospinning of nanofibers. J Appl Phys 2001; 89: 3018–3026
  • Yeo LY, Gagnon Z, Chang H-Ch. AC electrospray biomaterials synthesis. Biomaterials 2005; 26: 6122–6128
  • Yeo Y, Basaran OA, Park K. A new process for making reservoir-type microcapsules using ink-jet technology and interfacial phase separation. J Contr Rel 2003; 93: 161–173
  • Yoon SS, Heister SD, Epperson JT, Sojka PE. Modeling multi-jet mode electrostatic atomizaton using boundary element methods. J Electrostatics 2001; 50: 91–108
  • Zeleny J. Instability of electrified liquid surface. Phys Rev 1917; 10: 1–6
  • Zhao Y, Carvajal MT, Won Y-Y, Harris MT. Preparation of calcium alginate microgel beads in an electrodispersion reactor using an internal source of calcium carbonate nanoparticles. Langmuir 2007; 23: 12489–12496
  • Zhou Y, Sun T, Chan M, Zhang J, Han Z, Wang X, Toh Y, Chen JP, Yu H. Scalable encapsulation of hepatocytes by electrostatic spraying. J Biotech 2005; 117: 99–109
  • Zong X, Kim K, Fang D, Ran S, Hsiao BS, Chu B. Structure and process relationship of electrospun bioabsorbable nanofiber membranes. Polymer 2002; 43: 4403–4412

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.