Hot-melt extrusion microencapsulation of quercetin for taste-masking

References

• Ahn J, Lee H, Kim S, Park J, Ha T. The anti-obesity effect of quercetin is mediated by the AMPK and MAPK signaling pathways. Biochem Biophys Res Commun, 2008;373:545–9.
   PubMed Web of Science ®Google Scholar
• Celli GB, Ghanem A, Brooks MS-L. Bioactive encapsulated powders for functional foods—a review of methods and current limitations. Food Bioprocess Tech, 2015;8:1825–37.
   Web of Science ®Google Scholar
• Champagne CP, Fustier P. Microencapsulation for the improved delivery of bioactive compounds into foods. Curr Opin Biotechnol, 2007;18:184–90.
   PubMed Web of Science ®Google Scholar
• de Vos P, Faas MM, Spasojevic M, Sikkema J. Encapsulation for preservation of functionality and targeted delivery of bioactive food components. Int Diary J, 2010;20:292–302.
   Web of Science ®Google Scholar
• Drewnowski A, Gomez-Carneros C. Bitter taste, phytonutrients, and the consumer: a review. Am J Clin Nutr, 2000;72:1424–35.
   PubMed Web of Science ®Google Scholar
• Farag Y, Leopold CS. Investigation of drug release from pellets coated with different shellac types. Drug Dev Ind Pharm, 2011;37:193–200.
   PubMed Web of Science ®Google Scholar
• Fernandes CM, Teresa Vieira M, Veiga FJB. Physicochemical characterization and in vitro dissolution behavior of nicardipine–cyclodextrins inclusion compounds. Eur J Pharm Sci, 2002;15:79–88.
   PubMed Web of Science ®Google Scholar
• Gaudette NJ, Pickering GJ. Modifying bitterness in functional food systems. Crit Rev Food Sci Nutr, 2013;53:464–81.
   PubMed Web of Science ®Google Scholar
• Geraghty D, Peifer MA, Rubenstein I, Messing J. The primary structure of a plant storage protein: zein. Nucleic Acids Res, 1981;9:5163–74.
   PubMed Web of Science ®Google Scholar
• Gittings S, Turnbull N, Roberts CJ, Gershkovich P. Dissolution methodology for taste masked oral dosage forms. J Control Release, 2014;173:32–42.
   PubMed Web of Science ®Google Scholar
• Gonçalves V, Rodríguez-Rojo S, De Paz E, Mato C, Martín Á, Cocero M. Production of water soluble quercetin formulations by pressurized ethyl acetate-in-water emulsion technique using natural origin surfactants. Food Hydrocoll, 2015;51:295–304.
   Web of Science ®Google Scholar
• Hunt J. The composition of gastric juice. J Physiol (Lond), 1951;113:419–24.
   Google Scholar
• Hurtado-López P, Murdan S. Zein microspheres as drug/antigen carriers: a study of their degradation and erosion, in the presence and absence of enzymes. J Microencapsul, 2002;23:303–14.
   Web of Science ®Google Scholar
• Kawabata K, Mukai R, Ishisak A. Quercetin and related polyphenols: new insights and implications for their bioactivity and bioavailability. Food Funct, 2015;6:1399–417.
   PubMed Web of Science ®Google Scholar
• Kim IH, Lee H, Kim JE, Song KB, Lee YS, Chung DS, Min SC. Plum coatings of lemongrass oil-incorporating carnauba wax-based nanoemulsion. J Food Sci, 2013;78:E1551–9.
   PubMed Web of Science ®Google Scholar
• Lai F, Franceschini I, Corrias F, Sala MC, Cilurzo F, Sinico C, Pinib E. Maltodextrin fast dissolving films for quercetin nanocrystal delivery. A feasibility study. Carbohydr Polym, 2015;121:217–23.
   PubMed Web of Science ®Google Scholar
• Li B, Konecke S, Harich K, Wegiel L, Taylor LS, Edgar KJ. Solid dispersion of quercetin in cellulose derivative matrices influences both solubility and stability. Carbohydr Polym, 2013;92:2033–40.
   PubMed Web of Science ®Google Scholar
• Limmatvapirat S, Limmatvapirat C, Luangtana-anan M, Nunthanid J, Oguchi T, Tozuka Y, Yamamoto K, Puttipipatkhachorn S. Modification of physicochemical and mechanical properties of shellac by partial hydrolysis. Int J Pharm, 2004;278:41–9.
   PubMed Web of Science ®Google Scholar
• Lopes MA, Abrahim-Vieira B, Oliveira C, Fonte P, Souza AM, Lira T, Sequeira JA, Rodrigues CR, Cabral LM, Sarmento B, et al. Probing insulin bioactivity in oral nanoparticles produced by ultrasonication-assisted emulsification/internal gelation. Int J Nanomed, 2015;10:5865–80.
   PubMed Web of Science ®Google Scholar
• Luo Y, Wang Q. Zein-based micro-and nano-particles for drug and nutrient delivery: a review. J Appl Polym Sci, 2014;131:40696.
   Web of Science ®Google Scholar
• Madureira AR, Campos DA, Fonte P, Nunes S, Reis F, Gomes AM, Sarmento B, Pintado MM. Characterization of solid lipid nanoparticles produced with carnauba wax for rosmarinic acid oral delivery. RSC Adv, 2015;5:22665–73.
   Web of Science ®Google Scholar
• Maniruzzaman M, Boateng JS, Bonnefille M, Aranyos A, Mitchell JC, Douroumis D. Taste masking of paracetamol by hot-melt extrusion: an in vitro and in vivo evaluation. Eur J Pharm Biopharm, 2012;80:433–42.
   PubMed Web of Science ®Google Scholar
• Maniruzzaman M, Boateng JS, Chowdhry BZ, Snowden MJ, Douroumis D. A review on the taste masking of bitter APIs: hot-melt extrusion (HME) evaluation. Drug Dev Ind Pharm, 2014;40:145–56.
   PubMed Web of Science ®Google Scholar
• Meydani M, Hasan ST. Dietary polyphenols and obesity. Nutrients, 2010;2:737–51.
   PubMed Web of Science ®Google Scholar
• Milanovic J, Manojlovic V, Levic S, Rajic N, Nedovic V, Bugarski B. Microencapsulation of flavors in carnauba wax. Sensors (Basel), 2010;10:901–12.
   PubMed Web of Science ®Google Scholar
• Nabavi SF, Russo GL, Daglia M, Nabavi SM. Role of quercetin as an alternative for obesity treatment: you are what you eat! Food Chem, 2015;179:305–10.
   PubMed Web of Science ®Google Scholar
• Nazzaro F, Orlando P, Fratianni F, Coppola R. Microencapsulation in food science and biotechnology. Curr Opin Biotecnol, 2012;23:182–6.
   PubMed Web of Science ®Google Scholar
• Oehme A, Valotis A, Krammer G, Zimmermann I, Schreier P. Preparation and characterization of shellac-coated anthocyanin pectin beads as dietary colonic delivery system. Mol Nutr Food Res, 2011;55:S75–S85.
   PubMed Web of Science ®Google Scholar
• Ohara T, Kitamura S, Kitagawa T, Terada K. Dissolution mechanism of poorly water-soluble drug from extended release solid dispersion system with ethylcellulose and hydroxypropylmethylcellulose. Int J Pharm, 2005;302:95–102.
   PubMed Web of Science ®Google Scholar
• Özyazıcı M, Gökçe EH, Ertan G. Release and diffusional modeling of metronidazole lipid matrices. Eur J Pharm Biopharm, 2006;63:331–9.
   PubMed Web of Science ®Google Scholar
• Paliwal R, Palakurthi S. Zein in controlled drug delivery and tissue engineering. J Control Release, 2014;189:108–22.
   PubMed Web of Science ®Google Scholar
• Patel AR, Heussen PC, Hazekamp J, Drost E, Velikov KP. Quercetin loaded biopolymeric colloidal particles prepared by simultaneous precipitation of quercetin with hydrophobic protein in aqueous medium. Food Chem, 2012;133:423–9.
   PubMed Web of Science ®Google Scholar
• Raymond Y, Champagne CP. Dissolution of lipid-based matrices in simulated gastrointestinal solutions to evaluate their potential for the encapsulation of bioactive ingredients for foods. Int J Food Sci, 2014;2014:749630.
   PubMedGoogle Scholar
• Repka MA, Majumdar S, Kumar Battu S, Srirangam R, Upadhye SB. Applications of hot-melt extrusion for drug delivery. Expert Opin Drug Deliv, 2008;5:1357–76.
   PubMed Web of Science ®Google Scholar
• Sahoo NG, Kakran M, Shaal LA, Li L, Müller RH, Pal M, Tan LP. Preparation and characterization of quercetin nanocrystals. J Pharm Sci, 2011;100:2379–90.
   PubMed Web of Science ®Google Scholar
• Shukla D, Chakraborty S, Singh S, Mishra B. Fabrication and evaluation of taste masked resinate of risperidone and its orally disintegrating tablets. Chem Pharm Bull, 2009;57:337–45.
   PubMed Web of Science ®Google Scholar
• Singh A, Majumdar S, Deng W, Mohammed N, Chittiboyina A, Raman V, Shah S, Repka MA. Development and characterization of taste masked Efavirenz pellets utilizing hot melt extrusion. J Drug Del Sci Technol, 2013;23:157–63.
   Web of Science ®Google Scholar
• Soradech S, Limatvapirat S, Luangtana-anan M. Stability enhancement of shellac by formation of composite film: Effect of gelatin and plasticizers. J Food Eng, 2013;116:572–80.
   Web of Science ®Google Scholar
• Stippler E, Kopp S, Dressman J. Comparison of US pharmacopeia simulated intestinal fluid TS (without pancreatin) and phosphate standard buffer pH 6.8, TS of the international pharmacopoeia with respect to their use in in vitro dissolution testing. Dissolut Technol, 2004;11:6–11.
   Google Scholar
• Stummer S, Salar-Behzadi S, Unger FM, Oelzant S, Penning M, Viernstein H. Application of shellac for the development of probiotic formulations. Food Res Int, 2010;43:1312–20.
   Web of Science ®Google Scholar
• Sun-Waterhouse D, Wadhwa SS. Industry-relevant approaches for minimising the bitterness of bioactive compounds in functional foods: a review. Food Biopro Technol, 2013;6:607–27.
   Web of Science ®Google Scholar
• Tahara Y, Toko K. Electronic tongues – a review. IEEE Sens J, 2013;13:3001–11.
   Web of Science ®Google Scholar
• Vynckier AK, Dierickx L, Voorspoels J, Gonnissen Y, Remon JP, Vervaet C. Hot-melt co-extrusion: requirements, challenges and opportunities for pharmaceutical applications. J Pharm Pharmacol, 2014;66:167–79.
   PubMed Web of Science ®Google Scholar
• Wach A, Pyrzyńska K, Biesaga M. Quercetin content in some food and herbal samples. Food Chem, 2007;100:699–704.
   Web of Science ®Google Scholar
• Wang S, Moustaid-Moussa N, Chen L, Mo H, Shastri A, Su R, Bapat P, Kwun I, Shen CL. Novel insights of dietary polyphenols and obesity. J Nutr Biochem, 2014;25:1–18.
   PubMed Web of Science ®Google Scholar
• Woertz K, Tissen C, Kleinebudde P, Breitkreutz J. A comparative study on two electronic tongues for pharmaceutical formulation development. J Pharm Biomed Anal, 2011a;55:272–81.
   PubMed Web of Science ®Google Scholar
• Woertz K, Tissen C, Kleinebudde P, Breitkreutz J. Taste sensing systems (electronic tongues) for pharmaceutical applications. Int J Pharm, 2011b;417:256–71.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Cui L, Che X, Zhang H, Shi N, Li C, Chen Y, Kong W. Zein-based films and their usage for controlled delivery: origin, classes and current landscape. J Control Release, 2015;206:206–19.
   PubMed Web of Science ®Google Scholar