139
Views
9
CrossRef citations to date
0
Altmetric
Research Article

Nanodispersion-loaded mucoadhesive polymeric inserts for prolonged treatment of post-operative ocular inflammation

, , &
Pages 280-292 | Received 23 Jan 2017, Accepted 17 Apr 2017, Published online: 05 May 2017

References

  • Abha D, Sheeja K, Bhagyashri J. Design and evaluation of buccal film of diclofenac sodium. Int J Pharm Biol Sci, 2011;1(1):17–30.
  • Abhilash A, Jayaprakash S, Nagarajan M, Dhachinamoorthi D. Design and evaluation of timolol maleate ocuserts. Indian J Pharm Sci, 2005;67(3):311–14.
  • Adler J, Jayan A, Melia CD. A method for quantifying differential expansion within hydrating hydrophilic matrixes by tracking embedded fluorescent microspheres. J Pharm Sci, 1999;88(3):371–7.
  • Alanazi FK, Rahman AA, Mahrous GM, Alsarra IA. Formulation and physicochemical characterisation of buccoadhesive films containing ketorolac. J Drug Deliv Sci Technol, 2007;17(3):183–92.
  • Ali M, Shafie A. In vitro and in vivo evaluation of timolol maleate ocular inserts using different polymers. J Clin Exp Ophthalmol, 2012;3(8):1–9.
  • Alonso MJ, Sánchez A. The potential of chitosan in ocular drug delivery. J Pharm Pharmacol, 2003;55(11):1451–63.
  • Baba K, Tanaka Y, Kubota A, Kasai H, Yokokura S, Nakanishi H, Nishida K. A method for enhancing the ocular penetration of eye drops using nanoparticles of hydrolyzable dye. J Control Release, 2011;153(3):278–87.
  • Boateng J, Popescu A. Composite bi-layered erodible films for potential ocular drug delivery. Colloids Surf B Biointerfaces, 2016;145:353–61.
  • Boonsongrit Y, Mitrevej A, Mueller BW. Chitosan drug binding by ionic interaction. Eur J Pharm Biopharm, 2006;62(3):267–74.
  • Bravo-Osuna I, Vauthier C, Farabollini A, Palmieri GF, Ponchel G. Mucoadhesion mechanism of chitosan and thiolated chitosan-poly (isobutyl cyanoacrylate) core-shell nanoparticles. Biomaterials, 2007;28(13):2233–43.
  • Calvo P, Remunan-Lopez C, Vila-Jato J, Alonso M. Novel hydrophilic chitosan-polyethylene oxide nanoparticles as protein carriers. J Appl Polym Sci, 1997a;63(1):125–32.
  • Calvo P, Vila-Jato JL, Alonso MAJ. Evaluation of cationic polymer-coated nanocapsules as ocular drug carriers. Int J Pharm, 1997b;153(1):41–50.
  • Chen SC, Wu YC, Mi FL, Lin YH, Yu LC, Sung HW. A novel pH-sensitive hydrogel composed of N,O-carboxymethyl chitosan and alginate cross-linked by genipin for protein drug delivery. J Control Release, 2004;96(2):285–300.
  • Das S, Suresh PK, Desmukh R. Design of Eudragit RL 100 nanoparticles by nanoprecipitation method for ocular drug delivery. Nanomedicine, 2010;6(2):318–23.
  • Dave V, Paliwal S. A novel approach to formulation factor of aceclofenac eye drops efficiency evaluation based on physicochemical characteristics of in vitro and in vivo permeation. Saudi Pharm J, 2014;22(3):240–5.
  • De la Fuente M, Csaba N, Garcia-Fuentes M, Alonso MJ. Nanoparticles as protein and gene carriers to mucosal surfaces. Nanomedicine (Lond), 2008;3(6):845–57.
  • Deore V, Kumar R, Gide P. Development and statistical optimization of mucoadhesive buccal patches of indand indomethacin: In-vitro and ex-vivo evaluation. Int J Adv Pharm Biol Chem, 2013;2(2):405–22.
  • Diebold Y, Jarrin M, Saez V, Carvalho EL, Orea M, Calonge M, Seijo B, Alonso MJ. Ocular drug delivery by liposome–chitosan nanoparticle complexes (LCS-NP). Biomaterials, 2007;28(8):1553–64.
  • El-Bagory I, Bayomi M, Mahrous G, Alanazi F, Alsarra I. Effect of gamma irradiation on pluronic gels for ocular delivery of ciprofloxacin: in vitro evaluation. Aust J Basic Appl Sci, 2010;4:4490–8.
  • El-Khodairy K. Effect of physicochemical properties of drugs on the swelling index of the hydrophilic gantrez matrix. Alex J Parm Sci, 2001;15(1):35–9.
  • El-Nahas H, Hosny K. Chitosan-based floating microspheres of trimetazidin dihydrochloride; preparation and in vitro characterization. Ind J Pharm Sci, 2011;73(4):397–403.
  • Eouani C, Piccerelle P, Prinderre P, Bourret E, Joachim J. In-vitro comparative study of buccal mucoadhesive performance of different polymeric films. Eur J Pharm Biopharm, 2001;52(1):45–55.
  • Flach AJ, Kraff MC, Sanders DR, Tanenbaum L. The quantitative effect of 0.5% ketorolac tromethamine solution and 0.1% dexamethasone sodium phosphate solution on postsurgical blood-aqueous barrier. Arch Ophthalmol, 1988;106(4):480.
  • Ford JL. 2014. Design and evaluation of hydroxypropyl methylcellulose matrix tablets for oral controlled release: A historical perspective. In: Timmins P, Pygall SR, Melia CD, eds. Hydrophilic matrix tablets for oral controlled release. New York: Springer-Verlag, pp. 17–51.
  • Ford JL, Mitchell K. Thermal analysis of gels and matrix tablets containing cellulose ethers. Thermochim Acta, 1995;248:329–45.
  • Fraser-Smith EB, Matthews TR. Effect of ketorolac on pseudomonas aeruginosa ocular infection in rabbits. J Ocul Pharmacol Ther, 1988;4(2):101–9.
  • Fu RC, Lidgate DM. In vitro rabbit corneal permeability study of ketorolac, tromethamine, a non-steroidal anti-inflammatory agent. Drug Dev Ind Pharm, 1986;12(14):2403–30.
  • Fujimori J, Yoshihashi Y, Yonemochi E, Terada K. Application of Eudragit RS to thermo-sensitive drug delivery systems: II. Effect of temperature on drug permeability through membrane consisting of Eudragit RS/PEG 400 blend polymers. J Control Release, 2005;102(1):49–57.
  • Giovino C, Ayensu I, Tetteh J, Boateng JS. Development and characterisation of chitosan films impregnated with insulin loaded PEG-b-PLA nanoparticles (NPs): a potential approach for buccal delivery of macromolecules. Int J Pharm, 2012;428(1–2):143–51.
  • Gorle AP, Gattani SG. Design and evaluation of polymeric ocular drug delivery system. Chem Pharm Bull, 2009;57(9):914–19.
  • Heier J, Cheetham JK, DeGryse R, Dirks MS, Caldwell DR, Silverstone DE, Rosenthal A. Ketorolac tromethamine 0.5% ophthalmic solution in the treatment of moderate to severe ocular inflammation after cataract surgery: A randomized, vehicle-controlled clinical trial. Am J Ophthal, 1999;127(3):253–9.
  • Homburger F, Hayes JA, Pelikan EW, eds. 1983. A guide to general toxicology. Switzerland: Karger Publication, pp. 282.
  • Hou D, Gui R, Hu S, Huang Y, Feng Z, Ping Q. Preparation and characterization of novel drug-inserted-montmorillonite chitosan carriers for ocular drug delivery. Adv Nanoparticles, 2015;4(3):70–84.
  • Hu B, Pan C, Sun Y, Hou Z, Ye H, Hu B, Zeng X. Optimization of fabrication parameters to produce chitosan − tripolyphosphate nanoparticles for delivery of tea catechins. J Agric Food Chem, 2008;56(16):7451–8.
  • Joshi H, Wilson T. Calorimetric studies of dissolution of hydroxypropyl methylcellulose E5 (HPMC E5) in water. J Pharm Sci, 1993;82(10):1033–8.
  • Ju RT, Nixon PR, Patel MV, Tong DM. Drug release from hydrophilic matrices. 2. A mathematical model based on the polymer disentanglement concentration and the diffusion layer. J Pharm Sci, 1995;84(12):1464–77.
  • Kapanigowda UG, Nagaraja SH, Ramaiah B, Boggarapu PR. Improved intraocular bioavailability of ganciclovir by mucoadhesive polymer based ocular microspheres: development and simulation process in Wistar rats. DARU J Pharm Sci, 2015;23:49.
  • Kesarwani RK, Harikumar S, Rana A, Kashyap C, Kaur A, Seth N. Ocular implants: A novel approach to ocular drug delivery. Int J Drug Form Res, 2011;2(5):93–119.
  • Khan TA, Peh KK, Ch’ng HS. Mechanical, bioadhesive strength and biological evaluations of chitosan films for wound dressing. J Pharm Pharm Sci, 2000;3(3):303–11.
  • Khana R, Agarwal S, Ahuja A. Preparation and evaluation of muco-adhesive buccal films of clotrimazole for oral Candida infections. Indian J Pharm Sci, 1997;59(6):299–35.
  • Latha S, Selvamani P, Naveenkumar K, Ayyanar P, Silambarasi T. Formulation and evaluation of capecitabine nanoparticles for cancer therapy. Int J Biol Pharm Res, 2012;3(3):477–87.
  • Li X, Zhang Z, Chen H. Development and evaluation of fast forming nano-composite hydrogel for ocular delivery of diclofenac. Int J Pharm, 2013;448:96–100.
  • Liu H, Gao C. Preparation and properties of ionically cross‐linked chitosan nanoparticles. Polym Adv Technol, 2009;20(7):613–19.
  • Mishra D, Gilhotra R. Design and characterization of bioadhesive in-situ gelling ocular inserts of gatifloxacin sesquihydrate. DARU, 2008;16(1):1–8.
  • Mitra SK, Sundaram R, Venkataranganna MV, Gopumadhavan S, Prakash NS, Jayaram HD, Sarma DNK. Anti-inflammatory, antioxidant and antimicrobial activity of ophthacare brand, an herbal eye drops. Phytomedicine, 2000;7(2):123–7.
  • Mohamed MS, Eid A, Elgadir M, Mahdy MA. Preparation and release characteristics of itracinazole poymeric films for topical application. Int J Pharm Pharm Sci, 2013;5:167–70.
  • Morsi N, Ghorab D, Refai H, Teba H. Ketoroloac tromethamine loaded nanodispersion incorporated into thermosensitive in situ gel for prolonged ocular delivery. Int J Pharm, 2016;506:57–67.
  • Nagai N, Ito Y. A new preparation method for ophthalmic drug nanoparticles. Pharm Anal Acta, 2014;5(7):1–4.
  • Panyam J, Dali MM, Sahoo SK, Ma W, Chakravarthi SS, Amidon GL, Levy RJ, Labhasetwar V. Polymer degradation and in vitro release of a model protein from poly(D,L-lactide-co-glycolide) nano- and microparticles. J Control Release, 2003;92(1–2):173–87.
  • Prabha S, Zhou WZ, Panyam J, Labhasetwar V. Size-dependency of nanoparticle-mediated gene transfection: studies with fractionated nanoparticles. Int J Pharm, 2002;244(1–2):105–15.
  • Qaddoumi MG, Gukasyan HJ, Davda J, Labhasetwar V, Kim KJ, Lee V. Clathrin and caveolin-1 expression in primary pigmented rabbit conjunctival epithelial cells: role in PLGA nanoparticle endocytosis. Mol Vis, 2003;9:559–68.
  • Rajput G, Majmudar F, Patel J. Formulation and evaluation of mucoadhesive glipizide films. Acta Pharm, 2011;61(2):203–16.
  • Rampino A, Borgogna M, Blasi P, Bellich B, Cesaro A. Chitosan nanoparticles: Preparation, size evolution and stability. Int J Pharm, 2013;455(1–2):219–28.
  • Salsa T, Veiga F, Teixeira-Dias J, Pina M. Effect of polymer hydration on the kinetic release of drugs: a study of ibuprofen and ketoprofen in HPMC matrices. Drug Dev Ind Pharm, 2003;29(3):289–97.
  • Sankalia JM, Sankalia MG, Mashru RC. Drug release and swelling kinetics of directly compressed glipizide sustained-release matrices: Establishment of level A IVIVC. J Control Release, 2008;129(1):49–58.
  • Sankalia MG, Mashru RC, Sankalia JM, Sutariya VB. Reversed chitosan–alginate polyelectrolyte complex for stability improvement of alpha-amylase: optimization and physicochemical characterization. Eur J Pharm Biopharm, 2007;65(2):215–32.
  • Semalty M, Semalty A, Kumar G. Formulation and characterization of mucoadhesive buccal films of glipizide. Indian J Pharm Sci, 2008;70:43–8.
  • Shafie M, Fayek H. Formulation and evaluation of betamethasone sodium phosphate loaded nanoparticles for ophthalmic delivery. J Clin Exp Ophthalmol, 2013;4(2):1–11.
  • Shanmugam S, Ramvignesh T, Sundaramoorthy K, Ayyappan T, Vetrichelvan T. Design and evaluation of novel ophthalmic delivery system of aciclovir for herpes simplex infection. Res J Pharm Dosage Forms Technol, 2011;3(2):52–6.
  • Shivalingam MR, Durgabhavani G, Vaishnavi K, Priyanka K. Formulation and evaluation of diclofenac potassium transdermal patches for enhanced therapeutic efficacy. Indian J Res Pharm Biotechnol, 2014;2(3):1152–7.
  • Shivhare UD, Bodkhe PD, Bhusari KP, Mathur VB. Formulation and evaluation of buccoadhesive films of losartan potassium. Pharm Lett, 2010;2(5):251–60.
  • Singh V, Bushetti S, Raju SA, Ahmad R, Singh M. Glaucoma: A treatment by hydrogel. Pharma Sci Monitor Int J Pharm Sci, 2010;1(2):174–83.
  • Snejdrova E, Dittrich M. 2012. Pharmaceutical applications of plasticized polymers. In: Luqman M, ed. Recent advances in plasticizers. Shanghai: InTech, pp. 69–91.
  • Stoica R, Şomoghi R, Ion R. Preparation of chitosan-tripolyphosphate nanoparticles for the encapsulation of polyphenols extracted from rose hips. Dig J Nanomater Biostruct, 2013;8(3):955–63.
  • Sultana Y, Aqil M, Ali A, Zafar S. Evaluation of carbopol-methyl cellulose based sustained-release ocular delivery system for pefloxacin mesylate using rabbit eye model. Pharm Dev Technol, 2006;11(3):313–19.
  • Tandale YN, Wagh VD. Formulation and evaluation of dorzolamide hydrochloride polymeric film. Int J PharmTech Res, 2011;3:1817–24.
  • Tiwari SB, Murthy TK, Pai MR, Mehta PR, Chowdary PB. Controlled release formulation of tramadol hydrochloride using hydrophilic and hydrophobic matrix system. AAPS Pharmscitech, 2003;4(3):18–23.
  • Tiwari SB, Udupa N. Investigation into the potential of iontophoresis facilitated delivery of ketorolac. Int J Pharm, 2003;260(1):93–103.
  • Uglea CV. 1998. Oligomer technology and applications. Florida: CRC Press.
  • Vega E, Gamisans F, Garcia M, Chauvet A, Lacoulonche F, Gea M. PLGA nanospheres for the ocular delivery of flurbiprofen: drug release and interactions. J Pharm Sci, 2008;97(12):5306–17.
  • Werner U. 2004. In situ gelling nasal inserts for prolonged drug delivery. Freie Universität Berlin. Available at: http://www.diss.fu-berlin.de/diss/receive/FUDISS_thesis_000000001514
  • Williams RO, III, Reynolds TD, Cabelka TD, Sykora MA, Mahaguna V. Investigation of excipient type and level on drug release from controlled release tablets containing HPMC. Pharm Dev Technol, 2002;7(2):181–93.
  • Wu Y, Yang W, Wang C, Hu J, Fu S. Chitosan nanoparticles as a novel delivery system for ammonium glycyrrhizinate. Int J Pharm, 2005;295(1–2):235–45.
  • Wypych G. 2004. Handbook of plasticizers, Ontario: ChemTec Publishing.
  • Xu Y, Du Y. Effect of molecular structure of chitosan on protein delivery properties of chitosan nanoparticles. Int J Pharm, 2003;250(1):215–26.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.