Surface modified kokum butter lipid nanoparticles for the brain targeted delivery of nevirapine

References

• Almer, G., et al., 2015. Lipoprotein-related and apolipoprotein-mediated delivery systems for drug targeting and imaging. Current medicinal chemistry, 22 (31), 3631–3651.
   PubMed Web of Science ®Google Scholar
• Bohn, K.A., et al., 2016. Semi-automated rapid quantification of brain vessel density utilizing fluorescent microscopy. Journal of neuroscience methods, 270, 124–131.
   PubMed Web of Science ®Google Scholar
• Bondi, M.L., et al., 2010. Brain –targeted solid lipid nanoparticles containing Riluzole: preparation, characterization and biodistribution. Nanomedicine, 5 (1), 25–32.
   PubMed Web of Science ®Google Scholar
• Campos, E.V.R., et al., 2015. Polymeric and solid lipid nanoparticles for sustained release of Carbendazim and Tebuconazole in agricultural applications. Science reports. 5, 13809.
   PubMed Web of Science ®Google Scholar
• Chang, J., et al., 2009. Characterization of endocytosis of transferrin-coated PLGA nanoparticles by the blood-brain barrier. International journal of pharmaceutics, 379 (2), 285–292.
   PubMed Web of Science ®Google Scholar
• Chinedu, E., Arome, D., and Ameh, F.S., 2013. A new method for determining acute toxicity in animal models. Toxicology international, 20 (3), 224–226.
   PubMedGoogle Scholar
• Gabathuler, R., 2010. Approaches to transport therapeutic drugs across the blood-brain barrier to treat brain diseases. Neurobiological disorders, 37 (1), 48–57.
   PubMed Web of Science ®Google Scholar
• Ghasemiyeh, P., and Samani, S.M., 2018. Solid lipid nanoparticles and nanostructured lipid carriers as novel drug carriers: applications, advantages, and disadvantages. Research in pharmaceutical sciences, 13 (4), 288–303.
   PubMed Web of Science ®Google Scholar
• Goppert, T.M., and Muller, R.H., 2005. Polysorbate-stabilized solid lipid nanoparticles as colloidal carriers for intravenous targeting of drugs to the brain: comparision of plasma protein adsorption pattern. Journal of drug targeting, 13 (3), 179–187.
   PubMed Web of Science ®Google Scholar
• Gouda, R., Baishya, H., and Qing, Z., 2017. Application of mathematical models in drug release kinetics of Carbidopa and Levodopa ER tablets. Journal of developing drugs, 6 (2), 1–8.
   Google Scholar
• Gupta, S., et al., 2017. Systematic approach for the formulation and optimization of solid lipid nanoparticles of Efavirenz by high-pressure homogenization using design of experiments for brain targeting and enhanced bioavailability. Biomed research international, 2017, 1–18. Article ID 5984014.
   Web of Science ®Google Scholar
• Jia, Y., et al., 2016. Formulation, characterization, and in vitro/vivo studies of aclacinomycin A-loaded solid lipid nanoparticles. Drug delivery, 23 (4), 1317–1325.
   PubMed Web of Science ®Google Scholar
• Jimma, L.L., Woldu, M.A., and Satessa, G.D., 2014. New hope for eradication of HIV from the body: the role of polymeric nanomedicines in HIV/AIDS pharmacotherapy. Journal of nanobiotechnology, 12 (9), 2–6.
   PubMedGoogle Scholar
• 10 important health benefits of Garcinia indica. https://www.organicfacts.net/health-benefits/fruits/garcinia-indica.html/. Accessed on 02/11/18
   Google Scholar
• Kaur, A., and Jain, S., Tiwary, A. K., 2008. Mannan coated gelatin nanoparticles for sustained and targeted delivery of Didanosine: an in-vitro and in-vivo evaluation. Acta pharmaceutica. 58:61–74.
   PubMed Web of Science ®Google Scholar
• Kokum butter benefits and applications. http://www.kokumbutter.net/kokum-butter-benefits/. Accessed on 22/08/18
   Google Scholar
• Kokum oil. https://en.wikipedia.org/wiki/Kokum_oil. Accessed on 22/08/18.
   Google Scholar
• Kumar, G.P., Rambhau, D., and Apte, S.S., 2017. Brain targeting potential of intravenous carbamazepine SNEDDS. Journal of molecular pharmaceutics and organic process research, 5 (1), 1–7.
   Google Scholar
• Kuo, Y.C., Lin, P.I., and Wang, C.C., 2011. Targeting Nevirapine delivery across human brain microvascular endothelial cells using transferrin-grafted poly (lactide-co-glycolide) nanoparticles. Nanomed (lond), 6 (6), 1011–1026.
   PubMed Web of Science ®Google Scholar
• Kushwaha, A.K., et al., 2013. Development and evaluation of solid lipid nanoparticles of Roxifene Hydrochloride for enhanced bioavailability. Biomed research international, 2013, 1. Article ID 584549.
   Web of Science ®Google Scholar
• Lahkar, S., and Das, M.K., 2013. Surface modified polymeric nanoparticles for brain-targeted drug delivery. Current trends in biotechnology and pharmacy, 7 (4), 914–931.
   Google Scholar
• Lahkar, S., and Das, M.K., 2017. Effects of solvents on the development of biodegradable polymeric nanoparticles of Nevirapine. International journal of chemtech research, 10 (7), 735–747.
   Google Scholar
• Lockman, R.R., et al., 2004. Nanoparticles surface charge alters blood-brain barrier integrity and permeability. Journal of drug targeting, 12 (9-10), 635–641.
   PubMed Web of Science ®Google Scholar
• Makadia, H.K., and Siegel, S.J., 2011. Poly lactic-co-glycolic acid (PLGA) as biodegradable controlled drug delivery carrier. Polymers ( polymers), 3 (3), 1377–1397.
   PubMed Web of Science ®Google Scholar
• Mohanraj, V.J., and Chen, Y. 2006. Nanoparticles – A Review. Trop J pharm res, 5 (1), 561–573.
   Google Scholar
• Nair, R., et al., 2012. Formulation and evaluation of Chitosan solid lipid nanoparticles of carbamazepine. Lipids in health and disease, 11, 72.
   PubMed Web of Science ®Google Scholar
• OECD. OECD guideline for testing of chemicals: Acute Oral Toxicity – Acute Toxic Class Method. http://www.oecd.org/chemicalsafety/testing/oecdguidelinesforthetestingofchemicals.htm. Accessed on 22//08/2018.
   Google Scholar
• Pavanveena, C., Kavitha, K., and Kumar, S.N.A., 2010. Formulation and evaluation of Trimetazidine Hydrochloride loaded Chitosan microspheres. International Journal of applied pharmaceutics, 2 (2), 11–14.
   Google Scholar
• Raju, A., et al., 2014. Preparation and characterisation of nevirapine oral nanosuspensions. Indian journal of pharmaceutical sciences, 76 (1), 62–71.
   PubMed Web of Science ®Google Scholar
• Reimold, I., et al., 2008. Delivery of nanoparticles to the brain detected by fluorescence microscopy. European journal of pharmaceutics and biopharmaceutics, 70 (2), 627–632.
   PubMed Web of Science ®Google Scholar
• Ren, T., et al., 2009. Preparation and therapeutic efficacy of polysorbate-80-coated amphotericin B/PLA-B-PEG nanoparticles. Journal of biomaterials science. Polymer edition, 20 (10), 1369–1380.
   PubMed Web of Science ®Google Scholar
• Salatin, S., et al., 2017. Development of a nanoprecipitation method for the entrapment of a very water soluble drug into Eudragit RL nanoparticles. Research in pharmaceutical sciences, 12 (1), 1–14.
   PubMed Web of Science ®Google Scholar
• Sastre, V., and Ghaly, E.A., 2014. Controlled release of Ibuprofen nanoparticles: Physico-chemical characterization and drug release. Int J pharm pharm sci, 6 (8), 99–107.
   Google Scholar
• Shah, R., et al., 2014. Optimisation and stability assessment of solid lipid nanoparticles using particle size and zeta potential. Journal of physical sciences, 25 (1), 59–75.
   Google Scholar
• Tablot, G., 2015. Tropical exotic oils: properties and processing for use in food. In: G Tablot, ed. Speciality oils and fats in food and nutrition. Cambrige, UK, Woodhead Publishing Ltd, 87–123.
   Google Scholar
• Tan, I.L., and McArthur, J.C., 2012. HIV-associated neurological disorders: a guide to pharmacotherapy. CNS drugs, 26 (2), 123–134.
   PubMed Web of Science ®Google Scholar
• Usach, I., Melis, V., and Peris, J.E., 2013. Non-nucleoside reverse transcriptase inhibitors: a review on pharmacokinetics, pharmacodynamics, safety, and tolerability. Journal of international AIDS society, 16 (1), 1–14.
   PubMedGoogle Scholar
• Venkateswarlu, V., and Manjunath, K., 2004. Preparation, characterization and release kinetics of clozapine solid lipid nanoparticles. Journal of controlled release, 95 (3), 627–638.
   PubMed Web of Science ®Google Scholar
• Wilson, B., et al., 2008. Targeted delivery of tacrine into the brain with polysorbate 80 –coated poly(n-butylcyanoacrylate) nanoparticles. European Journal of pharmaceutics and biopharmaceutics, 70 (1), 75–84.
   PubMed Web of Science ®Google Scholar