Process optimisation, biocompatibility and anti-cancer efficacy of curcumin loaded gelatine microparticles cross-linked with dialdeyhde carboxymethyl cellulose

References

• Acharya, S., Dilnawaz, F., and Sahoo, S.K., 2009. Targeted epidermal growth factor receptor nanoparticle bioconjugates for breast cancer therapy. Biomaterials, 30(29), 5737–5750.
   PubMed Web of Science ®Google Scholar
• Ahmad, M.Z., et al., 2016. Progress in nanotechnology-based drug carrier in designing of curcumin nanomedicines for cancer therapy: current state-of-the-art. Journal of drug targeting, 24(4), 273–293.
   PubMed Web of Science ®Google Scholar
• Anand, P., et al., 2008. Curcumin and cancer: an “old-age” disease with an “age-old” solution. Cancer letters, 267(1), 133–164.
   PubMed Web of Science ®Google Scholar
• Brown, D. M., 2004. Drug delivery systems in cancer therapy. New York, NY: Humana Press.
   Google Scholar
• Cano-Higuita, D.M., Malacrida, C.R., and Telis, V., 2015. Stability of curcumin microencapsulated by spray and freeze drying in binary and ternary matrices of maltodextrin, gum arabic and modified starch. Journal of food processing and preservation, 39(6), 2049–2060.
   Web of Science ®Google Scholar
• Cao, F., et al., 2011. Lung-targeted delivery system of curcumin loaded gelatin microspheres. Drug delivery, 18(8), 545–554.
   PubMed Web of Science ®Google Scholar
• Delfiya, D.S.A., et al., 2014. Microencapsulation of turmeric oleoresin by spray drying and in vitro release studies of microcapsules. Journal of food process engineering, 38, 37–48.
   Web of Science ®Google Scholar
• Dhule, S.S., et al., 2014. The combined effect of encapsulating curcumin and c6 ceramide in liposomal nanoparticles against osteosarcoma. Molecular pharmaceutics, 11(2), 417–427.
   PubMed Web of Science ®Google Scholar
• Do Kim, K., et al., 2007. Optimization of parameters for the synthesis of zinc oxide nanoparticles by Taguchi robust design method. Colloids and surfaces A, 311(1–3), 170–173.
   Web of Science ®Google Scholar
• Elmore, S., 2007. Apoptosis: a review of programmed cell death. Toxicologic pathology, 35(4), 495–516.
   PubMed Web of Science ®Google Scholar
• El-Sherbiny, I.M. and Smyth, H., 2012. Controlled release pulmonary administration of curcumin using swellable biocompatible microparticles. Molecular pharmaceutics, 9(2), 269–280.
   PubMed Web of Science ®Google Scholar
• Elzoghby, A.O., 2013. Gelatin-based nanoparticles as drug and gene delivery systems: reviewing three decades of research. Journal of controlled release: official journal of the controlled release society, 172(3), 1075–1091.
   PubMed Web of Science ®Google Scholar
• Fatima, M.T., et al., 2016. Cell permeating nano-complexes of amphiphilic polyelectrolytes enhance solubility, stability, and anti-cancer efficacy of curcumin. Biomacromolecules, 17(7), 2375–2383.
   PubMed Web of Science ®Google Scholar
• Figueiredo, K.C.S., Alves, T.L.M., and Borges, C.P., 2009. Poly(vinyl alcohol) films crosslinked by glutaraldehyde under mild conditions. Journal of applied polymer science, 111(6), 3074–3080.
   Web of Science ®Google Scholar
• Gou, M., et al., 2011. Curcumin-loaded biodegradable polymeric micelles for colon cancer therapy in vitro and in vivo. Nanoscale, 3(4), 1558–1567.
   PubMed Web of Science ®Google Scholar
• Harada, T., et al., 2013. Diamide linked γ cyclodextrin dimers as molecular-scale delivery systems for the medicinal pigment curcumin to prostate cancer cells. Molecular pharmaceutics, 10(12), 4481–4490.
   PubMed Web of Science ®Google Scholar
• Jana, P., et al., 2015. Potential use of curcumin loaded carboxymethylated guar gum grafted gelatin film for biomedical applications. International journal of biological macromolecules, 75, 437–446.
   PubMed Web of Science ®Google Scholar
• Jiang, X., et al., 2016. Preparation, characterization and feasibility study of dialdehyde carboxymethyl cellulose as a novel crosslinking reagent. Carbohydrate polymers, 137, 632–641.
   PubMed Web of Science ®Google Scholar
• Kaja, S., et al., 2015. An optimized lactate dehydrogenase release assay for screening of drug candidates in neuroscience. Journal of pharmacological and toxicological methods, 73, 1–6.
   PubMed Web of Science ®Google Scholar
• Kunnumakkara, A.B., et al., 2017. Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases. British journal of pharmacology, 174(11), 1325–1348.
   PubMed Web of Science ®Google Scholar
• Lee, S.H., et al., 2011. Nano spray drying: a novel method for preparing protein nanoparticles for protein therapy. International journal of pharmaceutics, 403(1–2), 192–200.
   PubMed Web of Science ®Google Scholar
• Liu, W., Chen, X.D., and Selomulya, C., 2015. On the spray drying of uniform functional microparticles. Particuology, 22, 1–12.
   Web of Science ®Google Scholar
• Madhavan, K., et al., 2010. Evaluation of composition and crosslinking effects on collagen-based composite constructs. Acta biomaterialia, 6(4), 1413–1422.
   PubMed Web of Science ®Google Scholar
• Mahmood, K., et al., 2015. Recent developments in curcumin and curcumin based polymeric materials for biomedical applications: A review. International journal of biological macromolecules, 81, 877–890.
   PubMed Web of Science ®Google Scholar
• Malacrida, C.R., et al., 2015. Freeze-drying for microencapsulation of turmeric oleoresin using modified starch and gelatin. Journal of food processing and preservation, 39(6), 1710–1719.
   Web of Science ®Google Scholar
• Manickam, B., Sreedharan, R., and Elumalai, M., 2014. The natural water soluble cross-linking agent and its importance in the modified drug delivery systems: an overview. Current drug delivery, 11(1), 139–145.
   PubMed Web of Science ®Google Scholar
• Mcilwain, D.R., Berger, T., and Mak, T.W., 2013. Caspase Functions in Cell Death and Disease. Cold spring harbor perspectives in biology, 5(4), a008656–28.
   PubMed Web of Science ®Google Scholar
• Mehta, S.B., et al., 2015. Gelation of a monoclonal antibody at the silicone oil – water interface and subsequent rupture of the interfacial gel results in aggregation and particle formation. Journal of pharmaceutical sciences, 104(4), 1282–1290.
   PubMed Web of Science ®Google Scholar
• Microencapsulation Market–Forecast to 2022. 2017. Markets and markets reports.
   Google Scholar
• Mohan, P.R.K., et al., 2012. Vibrational spectroscopy water soluble complexes of curcumin with cyclodextrins: characterization by FT-raman spectroscopy. Vibrational spectroscopy, 62, 77–84.
   Web of Science ®Google Scholar
• Mu, C., et al., 2012. Preparation and properties of dialdehyde carboxymethyl cellulose crosslinked gelatin edible films. Food hydrocolloids, 27(1), 22–29.
   Web of Science ®Google Scholar
• Mu, C., et al., 2010. Collagen cryogel cross-linked by dialdehyde starch. Macromolecular materials engineering, 295, 100–107.
   Web of Science ®Google Scholar
• Munin, A. and Edwards-Lévy, F., 2011. Encapsulation of natural polyphenolic compounds; a review. Pharmaceutical, 3(4), 793–829.
   Google Scholar
• O’Toole, M.G.O., et al., 2012. Curcumin encapsulation in submicrometer spray-dried chitosan/tween 20 particles. Biomacromolecules, 13, 2309–2314.
   PubMed Web of Science ®Google Scholar
• Paramera, E.I., Konteles, S.J., and Karathanos, V.T., 2011. Stability and release properties of curcumin encapsulated in Saccharomyces cerevisiae, β-cyclodextrin and modified starch. Food chemistry, 125(3), 913–922.
   Web of Science ®Google Scholar
• Qin, S., et al., 2017. Drug self-delivery systems for cancer therapy. Biomaterials, 112, 234–247.
   PubMed Web of Science ®Google Scholar
• Salem, M., Rohani, S., and Gillies, E.R., 2014. Curcumin, a promising anti-cancer therapeutic: a review of its chemical properties, bioactivity and approaches to cancer cell delivery. RSC advances, 4(21), 10815–10829.
   Web of Science ®Google Scholar
• Sarika, P.R. and James, N.R., 2016. Polyelectrolyte complex nanoparticles from cationised gelatin and sodium alginate for curcumin delivery. Carbohydrate polymers, 148, 354–361.
   PubMed Web of Science ®Google Scholar
• Sarika, P.R. and Nirmala, R.J., 2016. Curcumin loaded gum arabic aldehyde-gelatin nanogels for breast cancer therapy. Materials science and engineering C: materials, 65, 331–337.
   PubMed Web of Science ®Google Scholar
• Sarika, P.R., et al., 2016. Preparation, characterization and biological evaluation of curcumin loaded alginate aldehyde – gelatin nanogels. Materials science and engineering C: materials, 68, 251–257.
   PubMed Web of Science ®Google Scholar
• Shaikh, J., et al., 2009. Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer. European journal of pharmaceutical sciences, 37(3–4), 223–230.
   PubMed Web of Science ®Google Scholar
• Sloth, J., 2007. Formation of enzyme containing particles by spray drying. Lyngby, Denmark: Technical University of Denmark.
   Google Scholar
• Sosnik, A. and Seremeta, K.P., 2015. Advantages and challenges of the spray-drying technology for the production of pure drug particles and drug-loaded polymeric carriers. Advances in colloid and interface science, 223, 40–54.
   PubMed Web of Science ®Google Scholar
• Tan, H., et al., 2015. Collagen cryogel cross-linked by naturally derived dialdehyde carboxymethyl cellulose. Carbohydrate polymers, 129, 17–24.
   PubMed Web of Science ®Google Scholar
• Tang, X., et al., 2005. Effect of curcumin on multidrug resistance in resistant human gastric carcinoma cell line SGC7901/VCR. Acta pharmaceutica sinica B, 26(8), 1009–1016.
   Web of Science ®Google Scholar
• Tengroth, C., et al., 2005. Cross-linking of gelatin capsules with formaldehyde and other aldehydes: an FTIR spectroscopy study. Pharmaceutical development and technology, 10(3), 405–412.
   PubMed Web of Science ®Google Scholar
• Tewes, F., Boury, F., and Benoit, J.P., 2006. In: S. Benita, ed. Biodegradable microspheres: advances in production technology. Boca Raton, FL: CRC Press, Taylor & Francis Group, 1.
   Google Scholar
• Tran, T.H., et al., 2014. Preparation and characterization of spray-dried gelatin microspheres encapsulating ganciclovir. Macromolecular research, 22(2), 124–130.
   Web of Science ®Google Scholar
• Wais, U., et al., 2016. Nanoformulation and encapsulation approaches for poorly water-soluble drug nanoparticles. Nanoscale, 8(4), 1746–1769.
   PubMed Web of Science ®Google Scholar
• Wang, Y., et al., 2009. Study on microencapsulation of curcumin pigments by spray drying. European food research and technology, 229(3), 391–396.
   Web of Science ®Google Scholar
• Xu, Y., et al., 2012. Feasibility study of a novel crosslinking reagent (alginate dialdehyde) for biological tissue fixation. Carbohydrate polymers, 87(2), 1589–1595.
   Web of Science ®Google Scholar
• Yadav, D. and Kumar, N., 2014. Nanonization of curcumin by antisolvent precipitation: process development, characterization, freeze drying and stability performance. International journal of pharmaceutics, 477(1–2), 564–577.
   PubMed Web of Science ®Google Scholar