186
Views
21
CrossRef citations to date
0
Altmetric
Original Articles

Microsponges enriched gel for enhanced topical delivery of 5-fluorouracil

, , , , &
Pages 677-691 | Received 03 Apr 2019, Accepted 09 Sep 2019, Published online: 24 Sep 2019

References

  • American Cancer Society. 2018. Cancer Facts & Figures 2018. Atlanta: American Cancer Society.
  • Amrutiya, N., Bajaj, A., and Madan, M., 2009. Development of microsponges for topical delivery of mupirocin. AAPS pharmscitech, 10(2), 402–409.
  • Arya, P., and Pathak, K., 2014. Assessing the viability of microsponges as gastro retentive drug delivery system of curcumin: optimization and pharmacokinetics. International journal of pharmaceutics, 460(1-2), 1–12.
  • Barrera, M.V., and Herrera, E., 2007. Topical chemotherapy for actinic keratosis and nonmelanoma skin cancer: current options and future perspectives. Actas dermo-sifiliográficas (english edition), 98(8), 556–562.
  • Bothiraja, C., et al., 2014. Investigation of ethyl cellulose microsponge gel for topical delivery of eberconazole nitrate for fungal therapy. Therapeutic delivery, 5(7), 781–794.
  • Chadawar, V., and Shaji, J., 2007. Microsponge delivery system. Current drug delivery, 4(2), 123–129.
  • Chaplin, S., 2016. Topical agents for preventing and treating actinic keratosis. Prescriber, 4, 32–40.
  • Dombe, S., et al., 2018. Development and evaluation of antifungal gel by using natural polymer. International journal of applied pharmaceutics, 7(12), 960–977.
  • Draize, J.H., Woodard, G., and Calvery, H.O., 1944. Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. Journal of pharmacology and experimental therapeutics, 82, 377–390.
  • Jain, S.K., and Puri, R., 2014. Development, characterization and in-vivo localization study of topical 5-fluorouracil gels: a comparative study with conventional formulation. Current drug delivery, 11(3), 401–414.
  • Jemal, A., et al., 2008. Cancer statistics, 2008. CA: A cancer journal for clinicians, 58, 71–96.
  • Jones, D.S., Woolfson, A.D., and Brown, A.F., 1997a. Textural analysis and flow rheometry of novel, bioadhesive antimicrobial oral gels. Pharmaceutical research, 14(4), 450–457.
  • Jones, D.S., Woolfson, A.D., and Brown, A.F., 1997b. Textural, viscoelastic and mucoadhesive properties of pharmaceutical gels composed of cellulose polymers. International journal of pharmaceutics, 151(2), 223–233.
  • Kaity, S., et al., 2010. Microsponges: a novel strategy for drug delivery system. Journal of advanced pharmaceutical technology & research, 1(3), 283.
  • Kaur, L., et al., 2014. Nanoethosomal formulation for skin targeting of amphotericin B: an in vitro and in vivo assessment. Journal of liposome research, 25(4), 294–307.
  • Kaur, L., Jain, S.K., and Singh, K., 2015. Vitamin E TPGS based nanogel for the skin targeting of high molecular weight anti-fungal drug: development and in vitro and in vivo assessment. RSC advances, 5(66), 53671–53686.
  • Kaur, L., et al., 2018. A mechanistic study to determine the structural similarities between artificial membrane strat-M™ and biological membranes and its application to carry out skin permeation study of amphotericin B nanoformulations. AAPS pharmscitech, 19(4), 1606–1624.
  • Kawashima, Y., et al., 1992. Control of prolonged drug release and compression properties of ibuprofen microsponges with acrylic polymer, eudragit RS, by changing their intraparticle porosity. Chemical & pharmaceutical bulletin, 40(1), 196–201.
  • Khallaf, R.A., Salem, H.F., and Abdelbary, A., 2016. 5-Fluorouracil shell-enriched solid lipid nanoparticles (SLN) for effective skin carcinoma treatment. Drug delivery, 23(9), 3452–3460.
  • Khan, M.A., et al., 2015. Novel carbopol-based transfersomal gel of 5-fluorouracil for skin cancer treatment: in-vitro characterization and in-vivo study. Drug delivery, 22(6), 795–802.
  • Khan, N.R., and Wong, T.W., 2018. 5-Fluorouracil ethosomes–skin deposition and melanoma permeation synergism with microwave. Artificial cells, nanomedicine, and biotechnology, 46(Suppl 1), 568–577.
  • Levin, V.A., 1980. Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability. Journal of medicinal chemistry, 23(6), 682–684.
  • Namdeo, A., and Jain, N.K., 1999. Niosomal delivery of 5-fluorouracil. Journal of microencapsulation, 16(6), 731–740.
  • Nishinari, K., et al., 2013. Parameters of texture profile analysis. Food science and technology research, 19(3), 519–521.
  • Orthaber, K., et al., 2017. Skin cancer and its treatment: novel treatment approaches with emphasis on nanotechnology. Journal of nanomaterials, 2017, 1.
  • Parker, W.B., and Cheng, Y.C., 1990. Metabolism and mechanism of action of 5-fluorouracil. Pharmacology & therapeutics, 48(3), 381–395.
  • Prasad, C., et al., 2011. Microsponge drug delivery system: a review. Journal of pharmacy research, 4, 1381–1384.
  • Puri, R., and Jain, S., 2012. Ethogel topical formulation for increasing the local bioavailability of 5-fluorouracil: a mechanistic study. Anti-cancer drugs, 23, 923–934.
  • Puri, R., and Kumar, J.S., 2013. Use of biochemical and microscopic techniques to determine enhanced skin permeation of nanovesicles: a mechanistic study. Pharmaceutical nanotechnology, 1(3), 213–223.
  • Siddalingam, R., and Chidambaram, K., 2016. Topical nano-delivery of 5-fluorouracil: preparation and characterization of water-in-oil nanoemulsion. Tropical journal of pharmaceutical research, 15(11), 2311–2319.
  • Singh, B.P., et al., 2016. Microsponge technology for novel topical drug delivery and oral drug delivery system: an overview. American journal of pharmtech research, 6, 71–88.
  • Yanyu, X., et al., 2012. The influence of the structure and the composition of water/AOT-Tween 85/IPM microemulsion system on transdermal delivery of 5-fluorouracil. Drug development and industrial pharmacy, 38(12), 1521–1529.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.