Development of levosulpiride-loaded solid lipid nanoparticles and their in vitro and in vivo comparison with commercial product

References

• Abdelbary, G. and Fahmy, R.H., 2009. Diazepam-loaded solid lipid nanoparticles: design and characterization. AAPS pharmscitech, 10, 211–219.
   PubMed Web of Science ®Google Scholar
• Agrawal, Y., Petkar, K.C., and Sawant, K.K., 2010. Development, evaluation and clinical studies of acitretin loaded nanostructured lipid carriers for topical treatment of psoriasis. International journal of pharmaceutics, 401, 93–102.
   PubMed Web of Science ®Google Scholar
• Ansari, M.J., et al., 2016. Enhanced oral bioavailability of insulin-loaded solid lipid nanoparticles: pharmacokinetic bioavailability of insulin-loaded solid lipid nanoparticles in diabetic rats. Drug delivery, 23, 1972–1979.
   PubMed Web of Science ®Google Scholar
• Araújo, J., et al., 2010. Optimization and physicochemical characterization of a triamcinolone acetonide-loaded NLC for ocular antiangiogenic applications. International journal of pharmaceutics, 1, 168–176.
   Web of Science ®Google Scholar
• Carrillo, C., et al., 2013. DNA delivery via cationic solid lipid nanoparticles (SLNs). European journal of pharmaceutical sciences, 49, 157–165.
   PubMed Web of Science ®Google Scholar
• Chitneni, M., et al., 2011. Intestinal permeability studies of sulpiride incorporated into self microemulsifying drug delivery system (SMEDDS). Pakistan journal of pharmaceutical sciences, 24, 113–121.
   PubMed Web of Science ®Google Scholar
• Cho, K.H., et al., 2015. Effect of sodium taurocholate on omeprazole buccal adhesive tablet: physicochemical characterization and pharmacokinetics in hamster. Current pharmaceutical analysis, 11, 98–103.
   Web of Science ®Google Scholar
• Das, S. and Chaudhury, A., 2011. Recent advances in lipid nanoparticle formulations with solid matrix for oral drug delivery. AAPS pharmscitech, 12, 62–76.
   PubMed Web of Science ®Google Scholar
• Din, F.U., et al., 2015a. Novel dual-reverse thermosensitive solid lipid nanoparticle-loaded hydrogel for rectal administration of flurbiprofen with improved bioavailability and reduced initial burst effect. European journal of pharmaceutics and biopharmaceutics, 94, 64–72.
   PubMed Web of Science ®Google Scholar
• Din, F.U., et al., 2015b. Development of a novel solid lipid nanoparticles loaded dual-reverse thermosensitive nanomicelle for intramuscular administration with sustained release and reduced toxicity. RSC advances, 5, 43687–43694.
   Web of Science ®Google Scholar
• Din, F.U., et al., 2017a. Irinotecan-loaded double-reversible thermogel with improved antitumor efficacy without initial burst effect and toxicity for intramuscular administration. Acta biomaterialia, 54, 239–248.
   PubMed Web of Science ®Google Scholar
• Din, F.U., et al., 2017b. Irinotecan-encapsulated double-reverse thermosensitive nanocarrier system for rectal administration. Drug delivery, 24, 502–510.
   PubMed Web of Science ®Google Scholar
• Din, F.U., et al., 2019. Development, in-vitro and in-vivo evaluation of ezetimibe-loaded solid lipid nanoparticles and their comparison with commercial product. Journal of drug delivery science and technology, 51, 583–590.
   Web of Science ®Google Scholar
• Din, F.U. and Khan, G.M., 2017. Development and characterisation of levosulpiride-loaded suppositories with improved bioavailability in vivo. Pharmaceutical development technology, 28, 1–30.
   Google Scholar
• Ghadiri, M., et al., 2012. Loading hydrophilic drug in solid lipid media as nanoparticles: statistical modeling of entrapment efficiency and particle size. International journal of pharmaceutics, 424, 128–137.
   PubMed Web of Science ®Google Scholar
• Hou, D., et al., 2003. The production and characteristics of solid lipid nanoparticles (SLNs). Biomaterials, 24, 1781–1785.
   PubMed Web of Science ®Google Scholar
• Ibrahim, W.M., Alomrani, A.H., and Yassin, A.E., 2014. Novel sulpiride-loaded solid lipid nanoparticles with enhanced intestinal permeability. International journal of nanomedicine, 9, 129–144.
   PubMed Web of Science ®Google Scholar
• Kim, D.S., et al., 2016. Comparison of solvent-wetted and kneaded l-sulpiride-loaded solid dispersions: powder characterization and in vivo evaluation. International journal of pharmaceutics, 511, 351–358.
   PubMed Web of Science ®Google Scholar
• Kim, J.S., et al., 2018. Novel revaprazan-loaded gelatin microsphere with enhanced drug solubility and oral bioavailability. Journal of microencapsulation, 35, 421–427.
   PubMed Web of Science ®Google Scholar
• Lavania, S., et al., 2016. Efficacy and safety of levosulpiride versus haloperidol injection in patients with acute psychosis: a randomized double-blind study. Clinical neuropharmacology, 39, 197–200.
   PubMed Web of Science ®Google Scholar
• Lim, S.J. and Kim, C.K., 2002. Formulation parameters determining the physicochemical characteristics of solid lipid nanoparticles loaded with all-trans retinoic acid. International journal of pharmaceutics, 243, 135–146.
   PubMed Web of Science ®Google Scholar
• Mehnert, W. and Mäder, K., 2012. Solid lipid nanoparticles: production, characterization and applications. Advanced drug delivery reviews, 64, 83–101.
   Web of Science ®Google Scholar
• Mustapha, O., et al., 2016. Novel piroxicam-loaded nanospheres generated by the electrospraying technique: physicochemical characterisation and oral bioavailability evaluation. Journal of microencapsulation, 33, 323–330.
   PubMed Web of Science ®Google Scholar
• Oh, D.H., et al., 2013. Flurbiprofen-loaded nanoparticles prepared with polyvinylpyrrolidone using Shirasu porous glass membranes and a spray-drying technique: nano-sized formation and improved bioavailability. Journal of microencapsulation, 30, 674–677.
   PubMed Web of Science ®Google Scholar
• Pandya, N.T., et al., 2018. Solid lipid nanoparticles as an efficient drug delivery system of olmesartan medoxomil for the treatment of hypertension. Colloids and surfaces B: biointerfaces, 165, 37–44.
   PubMed Web of Science ®Google Scholar
• Rashid, R., et al., 2015a. Effect of hydroxypropylcellulose and Tween 80 on physicochemical properties and bioavailability of ezetimibe-loaded solid dispersion. Carbohydrate polymers, 130, 26–31.
   PubMed Web of Science ®Google Scholar
• Rashid, R., et al., 2015b. Comparative study on solid self-nanoemulsifying drug delivery and solid dispersion system for enhanced solubility and bioavailability of ezetimibe. International journal of nanomedicine, 10, 6147–6159.
   PubMed Web of Science ®Google Scholar
• Reddy, L.H. and Murthy, R., 2005. Etoposide-loaded nanoparticles made from glyceride lipids: formulation, characterization, in vitro drug release, and stability evaluation. AAPS pharmscitech, 6, 158–166.
   PubMed Web of Science ®Google Scholar
• Rizvi, S.Z.H., et al., 2019. Simvastatin-loaded solid lipid nanoparticles for enhanced anti-hyperlipidemic activity in hyperlipidemia animal model. International journal of pharmaceutics, 560, 136–143.
   PubMed Web of Science ®Google Scholar
• Shah, R., et al., 2014. Optimisation and stability assessment of solid lipid nanoparticles using particle size and zeta potential. Journal of physical science, 25, 59–75.
   Google Scholar
• Siddiqui, K., et al., 2017. Physicochemical modifications and nano particulate strategies for improved bioavailability of poorly water soluble drugs. Pharmaceutical nanotechnology, 5, 1–9.
   Google Scholar
• Singh, S., et al., 2017. Formulation and in-vitro evaluation of solid lipid nanoparticles containing levosulpiride. The open nanomedicine journal, 4, 17–29.
   Google Scholar
• Wang, S., et al., 2012. Emodin loaded solid lipid nanoparticles: preparation, characterization and antitumor activity studies. International journal of pharmaceutics, 430, 238–246.
   PubMed Web of Science ®Google Scholar
• Yang, K.Y., et al., 2013. Silymarin-loaded solid nanoparticles provide excellent hepatic protection: physicochemical characterization and in vivo evaluation. International journal of nanomedicine, 8, 3333–3343.
   PubMed Web of Science ®Google Scholar
• Ying, X.Y., et al., 2011. Solid lipid nanoparticles modified with chitosan oligosaccharides for the controlled release of doxorubicin. Carbohydrate polymers, 84, 1357–1364.
   Web of Science ®Google Scholar
• Zhang, L., et al., 2015. Drug-in-cyclodextrin-in-liposomes: a novel drug delivery system for flurbiprofen. International journal of phamaceutics, 492, 40–45.
   PubMed Web of Science ®Google Scholar