Design and development of spirulina polysaccharide-loaded nanoemulsions with improved the antitumor effects of paclitaxel

References

• Barenwaldt, A., and Laubli, H., 2019. The sialoglycan-Siglec glyco-immune checkpoint - a target for improving innate and adaptive anti-cancer immunity. Expert opinion on therapeutic targets, 23, 839–853.
   PubMed Web of Science ®Google Scholar
• Buurman, E.T., et al., 2019. A novel hexavalent capsular polysaccharide conjugate vaccine (GBS6) for the prevention of neonatal group B streptococcal infections by maternal immunization. The Journal of infectious diseases, 220 (1), 105–115.
   PubMed Web of Science ®Google Scholar
• Chernykh, I., et al., 2020. Influence of common tansy (Tanacetum vulgare) flower polysaccharide complex on P-glycoprotein transporter activity in vitro. Pharmaceutical Chemistry Journal, 53 (12), 1133–1134.
   Web of Science ®Google Scholar
• Chernykh, I.V., et al., 2018. Vegetative polysaccharides: new target and direction of clinical use. Reviews on Clinical Pharmacology and Drug Therapy, 16 (4), 5–9.
   Google Scholar
• Dhupkar, P., and Gordon, N., 2017. Interleukin-2: old and new approaches to enhance immune-therapeutic efficacy. Advances in experimental medicine and biology, 995, 33–51.
   PubMed Web of Science ®Google Scholar
• Di Martino, A., et al., 2019. Multidrug delivery system based on polysaccharide nanocomplexes for controlled delivery of a combination of chemotherapeutics. Journal of Drug Delivery Science and Technology, 50, 90–98.
   Web of Science ®Google Scholar
• Di Martino, A., et al., 2018. Folic acid-chitosan-alginate nanocomplexes for multiple delivery of chemotherapeutic agents. Journal of Drug Delivery Science and Technology, 47, 67–76.
   Web of Science ®Google Scholar
• Guo, M. Z., et al., 2019. A novel polysaccharide obtained from Craterellus cornucopioides enhances immunomodulatory activity in immunosuppressive mice models via regulation of the TLR4-NF-kappaB pathway. Food and function, 10 (8), 4792–4801.
   Google Scholar
• Gupta, M., et al., 2016. TNF-α expression, risk factors, and inflammatory exposures in ovarian cancer: evidence for an inflammatory pathway of ovarian carcinogenesis? Human pathology, 54, 82–91.
   PubMed Web of Science ®Google Scholar
• Hui, Y., Jun-Li, H., and Chuang, W., 2019. Anti-oxidation and anti-aging activity of polysaccharide from Malus micromalus Makino fruit wine. International journal of biological macromolecules, 121, 1203–1212.
   PubMed Web of Science ®Google Scholar
• Kanevskiy, L.M., et al., 2019. The role of O-antigen in LPS-induced activation of human NK Cells. Journal of immunology research, 2019, 3062754.
   PubMed Web of Science ®Google Scholar
• Khalil, S.R., et al., 2018. Spirulina platensis attenuates the associated neurobehavioral and inflammatory response impairments in rats exposed to lead acetate. Ecotoxicology and environmental safety, 157, 255–265.
   PubMed Web of Science ®Google Scholar
• Kurd, F., and Samavati, V., 2015. Water soluble polysaccharides from Spirulina platensis: extraction and in vitro anti-cancer activity. International journal of biological macromolecules, 74, 498–506.
   PubMed Web of Science ®Google Scholar
• Lee, S.W., et al., 2019. TLR4-dependent effects of ISAg treatment on conventional T cell polarization in vivo. Animal cells and systems, 23 (3), 184–191.
   PubMed Web of Science ®Google Scholar
• Liu, X., et al., 2016. Geraniin inhibits LPS-induced THP-1 macrophages switching to M1 phenotype via SOCS1/NF-κB pathway . Inflammation, 39 (4), 1421–1433.
   PubMed Web of Science ®Google Scholar
• Liu, C., et al., 2013. Targeting the shift from M1 to M2 macrophages in experimental autoimmune encephalomyelitis mice treated with fasudil. PLoS One, 8 (2), e54841.
   PubMed Web of Science ®Google Scholar
• Liu, C.P., et al., 2017. NF-κB pathways are involved in M1 polarization of RAW 264.7 macrophage by polyporus polysaccharide in the tumor microenvironment. PloS one, 12 (11), e0188317.
   PubMed Web of Science ®Google Scholar
• Li, X., Wang, L., and Wang, B., 2017. Optimization of encapsulation efficiency and average particle size of Hohenbuehelia serotina polysaccharides nanoemulsions using response surface methodology. Food chemistry, 229, 479–486.
   PubMed Web of Science ®Google Scholar
• Li, G., et al., 2019. Functional characterization of a potent anti-tumor polysaccharide in a mouse model of gastric cancer. Life sciences, 219, 11–19.
   PubMed Web of Science ®Google Scholar
• Long, T., et al., 2018. Polygonatum sibiricum polysaccharides play anti-cancer effect through TLR4-MAPK/NF-κB signaling pathways. International journal of biological macromolecules, 111, 813–821.
   PubMed Web of Science ®Google Scholar
• Lu, Y., Li, W., and Yang, X., 2018. Soybean soluble polysaccharide enhances absorption of soybean genistein in mice. Food research international, 103, 273–279.
   PubMed Web of Science ®Google Scholar
• Mo, R., et al., 2011. The mechanism of enhancement on oral absorption of paclitaxel by N-octyl-O-sulfate chitosan micelles. Biomaterials, 32 (20), 4609–4620.
   PubMed Web of Science ®Google Scholar
• Moghimpour Bijani, F., Vallejo, J.G., and Rezaei, N., 2012. Toll-like receptor signaling pathways in cardiovascular diseases: challenges and opportunities. International reviews of immunology, 31 (5), 379–395.
   PubMed Web of Science ®Google Scholar
• Niu, J., et al., 2017. In Vitro Antioxidant activities and anti-diabetic effect of a polysaccharide from Schisandra sphenanthera in rats with type 2 diabetes. International journal of biological macromolecules, 94 (Pt A), 154–160.
   PubMed Web of Science ®Google Scholar
• Rai, V.K., et al., 2018. Nanoemulsion as pharmaceutical carrier for dermal and transdermal drug delivery: Formulation development, stability issues, basic considerations and applications. Journal of controlled release : official journal of the Controlled Release Society, 270, 203–225.
   PubMed Web of Science ®Google Scholar
• Ruijun, W., et al., 2015. Antitumor effects and immune regulation activities of a purified polysaccharide extracted from Juglan regia. International journal of biological macromolecules, 72, 771–775.
   PubMed Web of Science ®Google Scholar
• Sahu, P., et al., 2017. Nanoemulsion: a novel eon in cancer chemotherapy. Mini reviews in medicinal chemistry, 17 (18), 1778–1792.
   PubMed Web of Science ®Google Scholar
• Schmolz, L., Wallert, M., and Lorkowski, S., 2017. Optimized incubation regime for nitric oxide measurements in murine macrophages using the Griess assay. Journal of immunological methods, 449, 68–70.
   PubMed Web of Science ®Google Scholar
• Singh, Y., et al., 2017. Nanoemulsion: concepts, development and applications in drug delivery. Journal of controlled release : official journal of the Controlled Release Society, 252, 28–49.
   PubMed Web of Science ®Google Scholar
• Song, X., et al., 2017. Anti-tumor and immunomodulatory activities induced by an alkali-extracted polysaccharide BCAP-1 from Bupleurum chinense via NF-κB signaling pathway . International journal of biological macromolecules, 95, 357–362.
   PubMed Web of Science ®Google Scholar
• Voss, J., et al., 2017. Modulation of macrophage antitumor potential by apoptotic lymphoma cells. Cell death and differentiation, 24 (6), 971–983.
   PubMed Web of Science ®Google Scholar
• Wang, B., et al., 2018a. Preparation and evaluation of spirulina polysaccharide nanoemulsions. International journal of molecular medicine, 42 (3), 1273–1282.
   PubMed Web of Science ®Google Scholar
• Wang, B., et al., 2018b. Extraction of polysaccharide from spirulina and evaluation of its activities. Evidence-based complementary and alternative medicine: eCAM, 2018, 3425615.
   PubMed Web of Science ®Google Scholar
• Weaver, B.A., 2014. How Taxol/paclitaxel kills cancer cells. Molecular biology of the cell, 25 (18), 2677–2681.
   PubMed Web of Science ®Google Scholar
• Xie, X., et al., 2017. Enhanced antitumor activity of gemcitabine by polysaccharide-induced NK cell activation and immune cytotoxicity reduction in vitro/vivo. Carbohydrate polymers, 173, 360–371.
   PubMed Web of Science ®Google Scholar
• Xie, X., Zou, G., and Li, C., 2015. Antitumor and immunomodulatory activities of a water-soluble polysaccharide from Chaenomeles speciosa. Carbohydrate polymers, 132, 323–329.
   PubMed Web of Science ®Google Scholar
• Xu, H.Y., et al., 2019. Nanoemulsion improves hypoglycemic efficacy of berberine by overcoming its gastrointestinal challenge. Colloids and surfaces. B, Biointerfaces, 181, 927–934.
   PubMed Web of Science ®Google Scholar
• Zeng, Z., et al., 2019. Biofilm formation in Pseudoalteromonas lipolytica is related to IS5-like insertions in the capsular polysaccharide operon. FEMS Microbiology Ecology, 95 (6), fiz065.
   PubMed Web of Science ®Google Scholar
• Zhang, K., et al., 2018. Anti-inflammatory properties of GLPss58, a sulfated polysaccharide from Ganoderma lucidum. International journal of biological macromolecules, 107 (Pt A), 486–493.
   PubMed Web of Science ®Google Scholar
• Zhu, L., and Chen, L., 2019. Progress in research on paclitaxel and tumor immunotherapy. Cellular & molecular biology letters, 24, 40.
   PubMed Web of Science ®Google Scholar
• Zhu, C., et al., 2016. Selenium-containing phycocyanin from se-enriched spirulina platensis reduces inflammation in dextran sulfate sodium-induced colitis by inhibiting NF-κB activation. Journal of agricultural and food chemistry, 64 (24), 5060–5070.
   PubMed Web of Science ®Google Scholar