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Original Articles

Novel lipid–polymer hybrid nanoparticles incorporated in thermosensitive in situ gel for intranasal delivery of terbutaline sulphate

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Pages 577-594 | Received 10 Feb 2020, Accepted 17 Sep 2020, Published online: 02 Oct 2020

References

  • Abbas, H., Refai, H., and El Sayed, N., 2018. Superparamagnetic iron oxide-loaded lipid nanocarriers incorporated in thermosensitive in situ gel for magnetic brain targeting of clonazepam. Journal of pharmaceutical sciences, 107 (8), 2119–2127.
  • Aher, B.D., et al., 2018. A review on mucoadhesive buccal drug delivery system. World journal of pharmacy and pharmaceutical sciences, 7, 305–320.
  • Allah, A.K.A., and Abd-Al Hammid, S.N., 2017. Preparation and evaluation of chloramphenicol as thermosensitive ocular in-situ gel. Iraqi journal of pharmaceutical sciences, 21, 98–105.
  • Almeida, H., et al., 2013. Applications of poloxamers in ophthalmic pharmaceutical formulations: an overview. Expert opinion on drug delivery, 10 (9), 1223–1237.
  • Arora, P., Sharma, S., and Garg, S., 2002. Permeability issues in nasal drug delivery. Drug discovery today, 7 (18), 967–975.
  • Artursson, P., et al., 1994. Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2). Pharmaceutical research, 11 (9), 1358–1361.
  • Ban, M.M., et al., 2018. In-situ gel for nasal drug delivery. Indian journal of dental research, 8, 18763–18769.
  • Bommer, R., 2006. Drug delivery: nasal route. In: James Swarbrick, ed. Encyclopedia of pharmaceutical technology. New York: Informa Health, 1201–1208.
  • Borchard, G., et al., 1996. The potential of mucoadhesive polymers in enhancing intestinal peptide drug absorption. III: effects of chitosan-glutamate and carbomer on epithelial tight junctions in vitro. Journal of controlled release, 39 (2–3), 131–138.
  • Calvo, P., et al., 1996. Improved ocular bioavailability of indomethacin by novel ocular drug carriers. Journal of pharmacy and pharmacology, 48 (11), 1147–1152.
  • Calvo, P., Vila-Jato, J.L., and Alonso, MaJ., 1997. Evaluation of cationic polymer-coated nanocapsules as ocular drug carriers. International journal of pharmaceutics., 153 (1), 41–50.
  • Campbell, R.B., Balasubramanian, S.V., and Straubinger, R.M., 2001. Phospholipid-cationic lipid interactions: Influences on membrane and vesicle properties. Biochimica et biophysica acta (bba)–- biomembranes, 1512 (1), 27–39.
  • Cerchiara, T., et al., 2015. Chitosan based micro- and nanoparticles for colon-targeted delivery of vancomycin prepared by alternative processing methods. European journal of pharmaceutics and biopharmaceutics: official journal of arbeitsgemeinschaft fur pharmazeutische verfahrenstechnik e.v, 92, 112–119.
  • Chauhan, N., Rajvaidhya, S., and Dubey, B., 2012. Antiasthmatic effect of roots of clitorea ternatea linn. International journal of pharmaceutical sciences and research., 3, 1076–1079.
  • Chelladurai, S., Mishra, M., and Mishra, B., 2008. Design and evaluation of bioadhesive in-situ nasal gel of ketorolac tromethamine. Chemical & pharmaceutical bulletin, 56 (11), 1596–1599.
  • Chen, M., et al., 2009. Improved absorption of salmon calcitonin by ultraflexible liposomes through intranasal delivery. Peptides, 30 (7), 1288–1295.
  • Chen, S.-C., et al., 2004. A novel pH-sensitive hydrogel composed of N,O-carboxymethyl chitosan and alginate cross-linked by genipin for protein drug delivery. Journal of controlled release: official journal of the controlled release society, 96 (2), 285–300.
  • De, A., et al., 2013. Design and optimization of nasal in situ gel of ondansetron using factorial design. International journal of research in pharmacy and chemistry, 3, 659–673.
  • Deacon, M.P., et al., 2000. Atomic force microscopy of gastric mucin and chitosan mucoadhesive systems. Biochemical journal, 348 (3), 557–563.
  • Dehghan, M.H.G., and Marzuka, M., 2014. Lyophilized chitosan/xanthan polyelectrolyte complex based mucoadhesive inserts for nasal delivery of promethazine hydrochloride. Iranian journal of pharmaceutical research, 13, 769–784.
  • Dodane, V., Khan, M.A., and Merwin, J.R., 1999. Effect of chitosan on epithelial permeability and structure. International journal of pharmaceutics, 182 (1), 21–32.
  • El-Kamel, A., 2002. In vitro and in vivo evaluation of Pluronic F127-based ocular delivery system for timolol maleate. International journal of pharmaceutics, 241 (1), 47–55.
  • Fery, A., et al., 2003. Interaction of polyelectrolyte coated beads with phospholipid vesicles. Comptes rendus physique, 4 (2), 259–264.
  • Gan, Q., et al., 2005. Modulation of surface charge, particle size and morphological properties of chitosan-TPP nanoparticles intended for gene delivery. Colloids and surfaces. B, biointerfaces, 44 (2-3), 65–73.
  • Gavini, E., et al., 2005. Mucoadhesive microspheres for nasal administration of an antiemetic drug, metoclopramide: in-vitro/ex-vivo studies. Journal of pharmacy and pharmacology, 57 (3), 287–294.
  • Görner, T., et al., 1999. Lidocaine-loaded biodegradable nanospheres. I. Optimization of the drug incorporation into the polymer matrix. Journal of controlled release: official journal of the controlled release society, 57 (3), 259–268.
  • Gratieri, T., et al., 2010. A poloxamer/chitosan in situ forming gel with prolonged retention time for ocular delivery. European journal of pharmaceutics and biopharmaceutics: official journal of arbeitsgemeinschaft fur pharmazeutische verfahrenstechnik e.v, 75 (2), 186–193.
  • Hadinoto, K., Sundaresan, A., and Cheow, W.S., 2013. Lipid-polymer hybrid nanoparticles as a new generation therapeutic delivery platform: a review. European journal of pharmaceutics and biopharmaceutics: official journal of arbeitsgemeinschaft fur pharmazeutische verfahrenstechnik e.v, 85 (3 Pt A), 427–443.
  • Harris, A., et al., 1988. Effect of viscosity on particle size, deposition, and clearance of nasal delivery systems containing desmopressin. Journal of pharmaceutical sciences, 77 (5), 405–408.
  • Hoymann, H.G., 2012. Lung function measurements in rodents in safety pharmacology studies. Frontiers in pharmacology, 3, 156
  • Illum, L., 2003. Nasal drug delivery—possibilities, problems and solutions. Journal of controlled release: official journal of the controlled release society, 87 (1-3), 187–198.
  • Ismaiel, K., and Shaffie, M., 2012. Effects of fish oil and dexamethasone in experimentally-induced bronchial asthma. Australian journal of basic and applied sciences., 6, 497–506.
  • Javed, H., Shah, S.N.H., and Iqbal, F.M., 2018. Formulation development and evaluation of diphenhydramine nasal nano-emulgel. AAPS pharmscitech, 19 (4), 1730–1714.
  • Kao, H.J., et al., 2006. Characterization of pilocarpine-loaded chitosan/Carbopol nanoparticles. Iournal of pharmacy and pharmacology, 58 (2), 179–186.
  • Katiyar, S., et al., 2014. In situ gelling dorzolamide loaded chitosan nanoparticles for the treatment of glaucoma. Carbohydrate polymers, 102, 117–124.
  • Kayser, O., Lemke, A., and Hernández-Trejo, N., 2005. The impact of nanobiotechnology on the development of new drug delivery systems. Current pharmaceutical biotechnology, 6 (1), 3–5.
  • Klouda, L., 2015. Thermoresponsive hydrogels in biomedical applications: a seven-year update. European journal of pharmaceutics and biopharmaceutics: official journal of arbeitsgemeinschaft fur pharmazeutische verfahrenstechnik e.v, 97 (Pt B), 338–349.
  • Li, Q., et al., 2018. Preparation of a sustained-release nebulized aerosol of R-terbutaline hydrochloride liposome and evaluation of its anti-asthmatic effects via pulmonary delivery in guinea pigs. AAPS PharmSciTech, 19 (1), 232–241.
  • Liu, H., and Gao, C., 2009. Preparation and properties of ionically cross‐linked chitosan nanoparticles. Polymers for advanced technologies, 20 (7), 613–619.
  • Luppi, B., et al., 2010. Freeze-dried chitosan/pectin nasal inserts for antipsychotic drug delivery. European journal of pharmaceutics and biopharmaceutics: official journal of arbeitsgemeinschaft fur pharmazeutische verfahrenstechnik e.v, 75 (3), 381–387.
  • Maciel, V.B., et al., 2017. Electrostatic self-assembled chitosan-pectin nano-and microparticles for insulin delivery. Molecules, 22 (10), 1707.
  • Mahajan, H.S., and Gattani, S., 2010. In situ gels of metoclopramide hydrochloride for intranasal delivery: in vitro evaluation and in vivo pharmacokinetic study in rabbits. Drug delivery, 17 (1), 19–27.
  • Mainardes, R.M., et al., 2006. Liposomes and micro/nanoparticles as colloidal carriers for nasal drug delivery. Current drug delivery, 3 (3), 275–285.
  • Mcphail, D., et al., 2000. Liposomes encapsulating polymeric chitosan based vesicles—a vesicle in vesicle system for drug delivery. International journal of pharmaceutics, 200 (1), 73–86.
  • Mistry, A., Stolnik, S., and Illum, L., 2015. Nose-to-brain delivery: Investigation of the transport of nanoparticles with different surface characteristics and sizes in excised porcine olfactory epithelium. Molecular pharmaceutics, 12 (8), 2755–2766.
  • Monem, A.S., Ali, F.M., and Ismail, M.W., 2000. Prolonged effect of liposomes encapsulating pilocarpine HCl in normal and glaucomatous rabbits. International journal of pharmaceutics, 198 (1), 29–38.
  • Morsi, N., et al., 2017. Nanodispersion-loaded mucoadhesive polymeric inserts for prolonged treatment of post-operative ocular inflammation. Journal of microencapsulation, 34 (3), 280–292.
  • Moya, S., et al., 2000. Lipid coating on polyelectrolyte surface modified colloidal particles and polyelectrolyte capsules. Macromolecules, 33 (12), 4538–4544.
  • Mura, P., et al., 2018. In situ mucoadhesive-thermosensitive liposomal gel as a novel vehicle for nasal extended delivery of opiorphin. European journal of pharmaceutics and biopharmaceutics: official journal of arbeitsgemeinschaft fur pharmazeutische verfahrenstechnik e.v, 122, 54–61. ‏
  • Mygind, N., and Dahl, R., 1998. Anatomy, physiology and function of the nasal cavities in health and disease. Advanced drug delivery reviews, 29 (1-2), 3–12.
  • Nakhat, P., et al., 2007. Studies on buccoadhesive tablets of terbutaline sulphate. Indian journal of pharmaceutical sciences, 69 (4), 505–510.
  • Nilsson, H.T., et al., 1973. The metabolism of terbutaline in dog and rat. Xenobiotica; the fate of foreign compounds in biological systems, 3 (9), 615–623.
  • Ning, M., et al., 2005. Preparation, in vitro and in vivo evaluation of liposomal/niosomal gel delivery systems for clotrimazole. Drug development and industrial pharmacy, 31 (4–5), 375–383.
  • Özgüney, I.S., et al., 2006. Transdermal delivery of diclofenac sodium through rat skin from various formulations. AAPS PharmSciTech, 7 (4), 88–E45.
  • Pandey, S., et al., 2013. Chitosan-pectin polyelectrolyte complex as a carrier for colon targeted drug delivery. Journal of young pharmacists, 5 (4), 160–166.
  • Pund, S., Rasve, G., and Borade, G., 2013. Ex vivo permeation characteristics of venlafaxine through sheep nasal mucosa. European journal of pharmaceutical sciences: official journal of the European federation for pharmaceutical sciences, 48 (1–2), 195–201.
  • Rajoria, G., and Gupta, A., 2012. In-situ gelling system: a novel approach for ocular drug delivery. AJPTR, 2, 24–53.
  • Rao, M., Agrawal, D.K., and Shirsath, C., 2017. Thermoreversible mucoadhesive in situ nasal gel for treatment of Parkinson's disease. Drug development and industrial pharmacy, 43 (1), 142–150.
  • Salama, A.A., et al., 2015. Antiasthmatic effects of evening primrose oil in ovalbumin-allergic rats. Der pharmacia lettre, 7, 214–223.
  • Sankalia, M.G., et al., 2007. Reversed chitosan-alginate polyelectrolyte complex for stability improvement of alpha-amylase: optimization and physicochemical characterization. European journal of pharmaceutics and biopharmaceutics: official journal of arbeitsgemeinschaft fur pharmazeutische verfahrenstechnik e.v, 65 (2), 215–232.
  • Seslija, S., et al., 2016. Cross-linking of highly methoxylated pectin with copper: the specific anion influence. New journal of chemistry, 40 (2), 1618–1625.
  • Shahiwala, A., and Misra, A., 2004. Nasal delivery of levonorgestrel for contraception: an experimental study in rats. Fertility and sterility, 81, 893–898.
  • Soane, R., et al., 1999. Evaluation of the clearance characteristics of bioadhesive systems in humans. International journal of pharmaceutics, 178 (1), 55–65.
  • Soliman, G.M., Fetih, G., and Abbas, A.M., 2017. Thermosensitive bioadhesive gels for the vaginal delivery of sildenafil citrate: in vitro characterization and clinical evaluation in women using clomiphene citrate for induction of ovulation. Drug development and industrial pharmacy, 43 (3), 399–408.
  • Sun, S., et al., 2018. Roles of alcohol desolvating agents on the size control of bovine serum albumin nanoparticles in drug delivery system. Journal of drug delivery science and technology, 47, 193–199.
  • Tayel, S.A., et al., 2013. Promising ion-sensitive in situ ocular nanoemulsion gels of terbinafine hydrochloride: design, in vitro characterization and in vivo estimation of the ocular irritation and drug pharmacokinetics in the aqueous humor of rabbits. International journal of pharmaceutics., 443 (1-2), 293–305.
  • Ur-Rehman, T., Tavelin, S., and Gröbner, G., 2011. Chitosan in situ gelation for improved drug loading and retention in poloxamer 407 gels. International journal of pharmaceutics, 409 (1-2), 19–29.
  • Vibha, B., 2014. In-situ gel nasal drug delivery system – a review. International journal of pharmacy and pharmaceutical sciences, 4, 577–580.
  • Viswanath, V., et al., 2017. Formulation and evaluation of terbutaline sulphate loaded inhalation nanoparticles for pulmonary drug delivery. International journal of pharmaceutical sciences review and research, 42, 256–260.
  • Wang, X., Chi, N., and Tang, X., 2008. Preparation of estradiol chitosan nanoparticles for improving nasal absorption and brain targeting. European journal of pharmaceutics and biopharmaceutics: official journal of arbeitsgemeinschaft fur pharmazeutische verfahrenstechnik e.v, 70 (3), 735–740.
  • Wang, H., Yang, B., and Sun, H., 2017. Pectin-chitosan polyelectrolyte complex nanoparticles for encapsulation and controlled release of nisin. American journal of polymer science and technology, 3 (5), 82–88.
  • Wu, J., Su, Z.-G., and Ma, G.-H., 2006. A thermo- and pH-sensitive hydrogel composed of quaternized chitosan/glycerophosphate. International journal of pharmaceutics, 315 (1-2), 1–11.
  • Wu, Y., et al., 2005. Chitosan nanoparticles as a novel delivery system for ammonium glycyrrhizinate. International journal of pharmaceutics, 295 (1-2), 235–245.
  • Zaki, N.M., et al., 2007. Enhanced bioavailability of metoclopramide HCl by intranasal administration of a mucoadhesive in situ gel with modulated rheological and mucociliary transport properties. European journal of pharmaceutical sciences: official journal of the European federation for pharmaceutical sciences, 32 (4-5), 296–307.
  • Zhang, L., et al., 2008. Self-assembled lipid-polymer hybrid nanoparticles: a robust drug delivery platform. ACS nano, 2 (8), 1696–1702.
  • Zhang, L., and Zhang, L., 2010. Lipid–polymer hybrid nanoparticles: synthesis, characterization and applications. Nano life, 01 (01n02), 163–173.

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