Development of lipid nanoparticles for transdermal loteprednol etabonate delivery

References

• Aburahma, M.H. and Badr-Eldin, S.M., 2014. Compritol 888 ATO: a multifunctional lipid excipient in drug delivery systems and nanopharmaceuticals. Expert opinion on drug delivery, 11 (12), 1865–1883.
   PubMed Web of Science ®Google Scholar
• Afanas’ev, N.I., Selyanina, S.B., and Selivanova, N.V., 2008. Stabilization of the oleic acid-water emulsion with various kraft lignins. Russian journal of applied chemistry, 81 (10), 1851–1855.
   Web of Science ®Google Scholar
• Alberth, M., et al., 1991. Lipophilicity, solubility and permeability of loteprednol etabonate: a novel, soft anti-inflammatory steroid. Journal of biopharmaceutical statistics, 2 (2), 115–125.
   Google Scholar
• Almeida, E.D.P., et al., 2018. Skin permeation, biocompatibility and antitumor effect of chloroaluminum phthalocyanine associated to oleic acid in lipid nanoparticles. Photodiagnosis and photodynamic therapy, 24, 262–273.
   PubMed Web of Science ®Google Scholar
• Alsaqr, A., Rasoully, M., and Musteata, F.M., 2015. Investigating transdermal delivery of vitamin D3. AAPS PharmSciTech, 16 (4), 963–972.
   PubMed Web of Science ®Google Scholar
• Amon, M. and Busin, M., 2012. Loteprednol etabonate ophthalmic suspension 0.5 %: efficacy and safety for postoperative anti-inflammatory use. International ophthalmology, 32 (5), 507–517.
   PubMedGoogle Scholar
• Attama, A.A., Momoh, M.A., and Builders, P.F., 2012. Lipid nanoparticulate drug delivery systems: a revolution in dosage form design and development. Recent advances in novel drug carrier systems, 5, 107–140.
   Google Scholar
• Bhalekar, M., Upadhaya, P., and Madgulkar, A., 2017. Formulation and characterization of solid lipid nanoparticles for an anti-retroviral drug darunavir. Applied nanoscience, 7 (1–2), 47–57.
   Web of Science ®Google Scholar
• Chen, G., et al., 2008. In vitro dexamethasone release from nanoparticles and its pharmacokinetics in the inner ear after administration of the drug-loaded nanoparticles via the round window. Nan fang yi ke da xue xue bao, 28 (6), 1022–1024.
   PubMedGoogle Scholar
• Comstock, T.L. and Sheppard, J.D., 2018. Loteprednol etabonate for inflammatory conditions of the anterior segment of the eye: twenty years of clinical experience with a retrometabolically designed corticosteroid. Expert opinion on pharmacotherapy, 19 (4), 337–353.
   PubMed Web of Science ®Google Scholar
• Das, A. and Panda, S., 2017. Use of topical corticosteroids in dermatology: an evidence-based approach. Indian journal of dermatology, 62 (3), 237–250.
   PubMed Web of Science ®Google Scholar
• De Oliveira, E.G., et al., 2019. Tailoring structural properties of spray-dried methotrexate-loaded poly (lactic acid)/poloxamer microparticle blends. Journal of materials science, 30 (1), 12.
   Web of Science ®Google Scholar
• Elmowafy, M., et al., 2018. Multifunctional carbamazepine loaded nanostructured lipid carrier (NLC) formulation. International journal of pharmaceutics, 550 (1–2), 359–371.
   PubMed Web of Science ®Google Scholar
• Fong, R., et al., 2019. Loteprednol etabonate (submicron) ophthalmic gel 0.38% dosed three times daily following cataract surgery: integrated analysis of two phase III clinical studies. Clinical ophthalmology, 13, 1427–1438.
   PubMed Web of Science ®Google Scholar
• Fukushima, S., Takahashi, M., and Yamaguchi, M., 1976. Effect of cetostearyl alcohol on stabilization of oil-in-water emulsion: I. Difference in the effect by mixing cetyl alcohol with stearyl alcohol. Journal of colloid and interface science, 57 (2), 201–206.
   Web of Science ®Google Scholar
• Ghadiri, M., et al., 2012. Loading hydrophilic drug in solid lipid media as nanoparticles: statistical modeling of entrapment efficiency and particle size. International journal of pharmaceutics, 424 (1–2), 128–137.
   PubMed Web of Science ®Google Scholar
• Goldstein, B.G., et al., 2021. Topical corticosteroids: use and adverse effects. In: R.P. Dellavalle and M.L. Levy, eds. Topical corticosteroids.
   Google Scholar
• Gupta, V. and Trivedi, P., 2015. Ex vivo localization and permeation of cisplatin from novel topical formulations through excised pig, goat, and mice skin and in vitro characterization for effective management of skin-cited malignancies. Artificial cells, nanomedicine, and biotechnology, 43 (6), 373–382.
   PubMed Web of Science ®Google Scholar
• Han, Y. and Segall, A., 2015. A validated specific stability-indicating RP-HPLC assay method for the determination of loteprednol etabonate in eye drops. Journal of chromatographic science, 53 (5), 761–766.
   PubMed Web of Science ®Google Scholar
• Houston, D.M.J., et al., 2017. Anti-inflammatory activity of Punica granatum L. (Pomegranate) rind extracts applied topically to ex vivo skin. European journal of pharmaceutics and biopharmaceutics, 112, 30–37.
   PubMed Web of Science ®Google Scholar
• International Conference on Harmonization. 2005. Validation of analytical procedures: text and methodology, vol 11. Geneva, Switzerland: ICH.
   Google Scholar
• Jensen, L.B., Petersson, K., and Nielsen, H.M., 2011. In vitro penetration properties of solid lipid nanoparticles in intact and barrier-impaired skin. European journal of pharmaceutics and biopharmaceutics, 79 (1), 68–75.
   PubMed Web of Science ®Google Scholar
• Jia, L., et al., 2010. Preparation and characterization of silybin-loaded nanostructured lipid carriers. Drug delivery, 17 (1), 11–18.
   PubMed Web of Science ®Google Scholar
• Kahraman, E., et al., 2018. The combination of nanomicelles with terpenes for enhancement of skin drug delivery. International journal of pharmaceutics, 551 (1–2), 133–140.
   PubMed Web of Science ®Google Scholar
• Kar, M., et al., 2019. Current developments in excipient science: implication of quantitative selection of each excipient in product development. In: R.K. Tekade, ed. Basic fundamentals of drug delivery. Cambridge, MA: Academic Press, 29–83.
   Google Scholar
• Khames, A., et al., 2019. Natamycin solid lipid nanoparticles - sustained ocular delivery system of higher corneal penetration against deep fungal keratitis: preparation and optimization. International journal of nanomedicine, 14, 2515–2531.
   PubMed Web of Science ®Google Scholar
• Khandelmai, N.P., Bhide, P., and Nachinolkar, R., 2019. Formulation and evaluation of solubility enhanced in situ gelling eye drops of loteprednol etabonate. Asian journal of pharmaceutical and clinical research, 12 (12), 209–216.
   Google Scholar
• Korting, H.C. and Schäfer-Korting, M., 2010. Carriers in the topical treatment of skin disease. Drug delivery, 197, 435–468.
   Google Scholar
• LGC GmbH. 2017. Certificate of analysis reference standard loteprednol etabonate (TGZ II. D-14943). Luckenwalde, Germany: LGC GmbH.
   Google Scholar
• Ng, S., et al., 2010. A comparative study of transmembrane diffusion and permeation of ibuprofen across synthetic membranes using franz diffusion cells. Pharmaceutics, 2 (2), 209–223.
   PubMedGoogle Scholar
• Nihant, N., et al., 1994. Polylactide microparticles prepared by double emulsion/evaporation technique. I. Effect of primary emulsion stability. Pharmaceutical research, 11 (10), 1479–1484.
   PubMed Web of Science ®Google Scholar
• Noble, S. and Goa, K.L., 1998. Loteprednol etabonate: clinical potential in the management of ocular inflammation. BioDrugs, 10 (4), 329–339.
   PubMed Web of Science ®Google Scholar
• Olatunji, O., et al., 2013. Influence of array interspacing on the force required for successful microneedle skin penetration: theoretical and practical approaches. Journal of pharmaceutical sciences, 102 (4), 1209–1221.
   PubMed Web of Science ®Google Scholar
• Özdemir, S., et al., 2018. Eplerenone nanoemulsions for treatment of hypertension. Part I: experimental design for optimization of formulations and physical characterization. Journal of drug delivery science and technology, 45, 357–366.
   Web of Science ®Google Scholar
• Özdemir, S., 2016. Aldosteron antagonisti eplerenonun yeni formülasyonlarının geliştirilmesi üzerine çalışmalar. İstanbul, Turkey: İstanbul Üniversitesi Sağlık Bilimleri Enstitüsü.
   Google Scholar
• Padhye, S.G. and Nagarsenker, M.S., 2013. Simvastatin solid lipid nanoparticles for oral delivery: formulation development and in vivo evaluation. Indian journal of pharmaceutical sciences, 75 (5), 591–598.
   PubMed Web of Science ®Google Scholar
• Parra, A., et al., 2016. Ex vivo permeation of carprofen from nanoparticles: a comprehensive study through human, porcine and bovine skin as anti-inflammatory agent. International journal of pharmaceutics, 501 (1–2), 10–17.
   PubMed Web of Science ®Google Scholar
• Patra, J.K., et al., 2018. Nano based drug delivery systems: recent developments and future prospects. Journal of nanobiotechnology, 16 (1), 1–33.
   PubMed Web of Science ®Google Scholar
• Pepe, D., et al., 2016. Transportan in nanocarriers improves skin localization and antitumor activity of paclitaxel. International journal of nanomedicine, 11, 2009–2019.
   PubMed Web of Science ®Google Scholar
• Ramadon, D., et al., 2022. Enhancement strategies for transdermal drug delivery systems: current trends and applications. Drug delivery and translational research, 12 (4), 734–758.
   Web of Science ®Google Scholar
• Rathi, S.K. and D’Souza, P., 2012. Rational and ethical use of topical corticosteroids based on safety and efficacy. Indian journal of dermatology, 57 (4), 251–259.
   PubMedGoogle Scholar
• Sahoo, S., et al., 2020. Formulation and evaluation of sustained release in situ gel of loteprednol etabonate by using 3 2 full factorial design. Aegaeum journal, 8 (4), 566.
   Google Scholar
• Schmid-Wendtner, M.H. and Korting, H.C., 2006. The pH of the skin surface and its impact on the barrier function. Skin pharmacology and physiology, 19 (6), 296–302.
   PubMed Web of Science ®Google Scholar
• Shimojo, A.A.M., et al., 2019. Evaluation of the influence of process parameters on the properties of resveratrol-loaded NLC using 22 full factorial design. Antioxidants, 8 (8), 272.
   Web of Science ®Google Scholar
• Siekmann, B. and Westesen, K., 1994. Thermoanalysis of the recrystallization process of melt-homogenized glyceride nanoparticles. Colloids and surfaces B: Biointerfaces, 3 (3), 159–175.
   Google Scholar
• Souto, E.B., Almeida, A.J., and Müller, R.H., 2007. Lipid nanoparticles (SLN®, NLC®) for cutaneous drug delivery: structure, protection and skin effects. Journal of biomedical nanotechnology, 3 (4), 317–331.
   Web of Science ®Google Scholar
• Tatke, A., et al., 2018. In situ gel of triamcinolone acetonide-loaded solid lipid nanoparticles for improved topical ocular delivery: tear kinetics and ocular disposition studies. Nanomaterials, 9 (1), 33.
   Web of Science ®Google Scholar
• Uchechi, O., Ogbonna, J.D., and Attama, A.A., 2014. Nanoparticles for dermal and transdermal drug delivery. Application of nanotechnology in drug delivery, 4, 193–227.
   Google Scholar
• Üner, M., Karaman, E., and Aydoğmuş, Z., 2014a. Solid lipid nanoparticles and nanostructured lipid carriers of loratadine for topical application: physicochemical stability and drug penetration through rat skin. Tropical journal of pharmaceutical research, 13 (5), 653.
   Web of Science ®Google Scholar
• Üner, M., et al., 2014b. Solid lipid nanoparticles and nanostructured lipid carriers of celecoxib for topical application – preparation. characterization and drug penetration through rat skin. Current nanoscience, 10 (4), 532–542.
   Web of Science ®Google Scholar
• Üner, M., Yener, G., and Ergüven, M., 2019. Design of colloidal drug carriers of celecoxib for use in treatment of breast cancer and leukemia. Materials science and engineering: C, 103, 109874.
   PubMed Web of Science ®Google Scholar
• Vieira, S., et al., 2020. Sucupira oil-loaded nanostructured lipid carriers (NLC): lipid screening, factorial design, release profile, and cytotoxicity. Molecules, 25 (3), 685.
   PubMed Web of Science ®Google Scholar
• Wissing, S.A., Lippacher, A., and Müller, R.H., 2001. Investigations on the occlusive properties of solid lipid nanoparticles (SLN). Journal of cosmetic science, 52 (5), 313–324.
   PubMed Web of Science ®Google Scholar