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Journal of Microencapsulation
Micro and Nano Carriers
Volume 16, 1999 - Issue 6
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Research Article

Release characteristics of chitosan treated alginate beads: II. Sustained release of a low molecular drug from chitosan treated alginate beads

A. D. Sezer, J. Akbuga Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, University ofMarmara, 81010, Haydarpasa-Istanbul, Turkey
Pages 687-696 | Published online: 29 Sep 2008

References

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  • MURATA Y., MAEDA, T., MIYAMilt) E, and KAWASEENIA, S., 1993b, Preparation of chitosan-reinforced alginate gel beads-effects of chitosan on gel matrix erosion. International Journal of Pharmaceutics, 96, 139–145.
  • MURATA Y., NAKADA, K, MIYAmilt) E., KAWASHINA, S., and SEQ S. H., 1993a, Influence of erosion of calcium-induced alginate gel matrix on the release of brilliant blue. Journal of Controlled Release, 23, 21–26.
  • OKFTAmAFT A. 0, ANEEEN B., CHI4 W, and GOZSENI M F. A., 1996, Modulation of protein release from chitosan-alginate microcapsules using the pH-sensitive polymer hydroxypropyl methylcellulose acetate succinate. Journal of Microencapsulation, 13, 497–508.
  • OSTBERG T., and GRAFFER, C., 1994, Calcium alginate matrices for oral multiple unit administration III influence of calcium concentration, amount of drug added and alginate characteristics of drug release. International Journal of Pharmaceutics, 111, 271–282.
  • PEFPAS, N. A., 1987, Swelling controlled release systems. Recent development and applications. In Controlled Drug Delivery, edited by B. W. Muller (Stuttgart: Wissenschaftliche Verlagsgesellschaft mbH), pp. 161–173.
  • PFISTER, G., BAHAEIR, M., and KCR-M F., 1986, Release characteristics of herbicides from calcium alginate gel formulations. Journal of Controlled Release, 3,229–233.
  • POLK, A., ANEEEN B., YAQ K D., PFNI T., and GCCSEN M. F. A., 1994, Controlled release of albumin from chitosan-alginate microcapsules. Journal of Pharmaceutical Sciences, 83, 178–185.
  • SEZER, A. D., and AxBUTGA, J., 1995, Controlled release of piroxicam from chitosan beads. International Journal of Pharmaceutics, 121, 113–116.
  • SEZER, A. D., and AxBUTGA, J., 1998, Release characteristics of chitosan treated alginate beads: I. Sustained release of macromolecular drug from chitosan treated alginate beads. Journal of Microencapsulation, 16, 195–203.

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