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International Journal of Hyperthermia Volume 18, 2002 - Issue 3
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Research Article

A phase I study of fever-range whole body hyperthermia (FR-WBH) in patients with advanced solid tumours: correlation with mouse models

W. G. Kraybill Division of Surgical Oncology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
,
T. Olenki Department of Surgery, The Taussig Cancer Center, Cleveland Clinic Foundation, Cleveland, OH 44102, USA
,
S. S. Evans Department of Immunology
,
J. R. Ostberg Department of Immunology
,
K. A. O'Leary Department of Anesthesiology and Pain Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
,
J. F. Gibbs Division of Surgical Oncology
&
E. A. Repasky Department of Immunology
 show all
Pages 253-266 | Published online: 09 Jul 2009

  • Nauts HC, Gowler GA, Bogatko, FH. A review of the influence of bacterial infections and bacterial products (Coley's toxin) on malignant tumors in men. Acta Med Scand 1953; 276: 1.
  • Miller TR, Nicholson JT. End results in reticulum cell sarcome of bone treated by bacterial toxin therapy alone or combined with surgery and/or radiotherapy (47 cases) or with concurrent infection (5 cases). Cancer 1971; 27: 524-48.
  • Suit HD, Shwayder M. Hyperthermia: potential as an anti-tumor agent. Cancer 1974; 34: 122-9.
  • FaIk MH, Issels RD. Hyperthermia in oncology. Int J Hyperthermia 2001; 17: 1-18.
  • Samulski TV, Grant WJ, Oleson JR, Leopold KA, Dewhirst MW, Vallario P, Bliven J. Clinical experience with a multi-element ultrasonic hyperthermia system: analysis of treatment temperatures. Int J Hyperthermia 1990; 6: 909-22.
  • Feyerabend T, Wiedemann GJ, Jager B, Vesely H, Mahlmann B, Richter E. Local hyperthermia, radiation, and chemotherapy in recurrent breast cancer is effective except for inflammatory disease. Int J Radiat Oncol Biol Phys 2001; 49: 1317-25.
  • Suzuki M, Saga Y, Tsukagoshi S, Tamura N, Sato I. Recurrent ovarian clear cell carcinoma: complete remission after radiation in combination with hyperthermia; a case study and in vitro study. Cancer Biother Radiopharm 2000; 15: 625-8.
  • Overgaard J, Gonzalez DG, Hulshof MCCM, Arcangeli G, DaIh O, Mella O, Bentzen SM. Hyperthermia as an adjuvant to radiation therapy of recurrent or metastatic malignant melanoma. A multicentre randomized trial by the European Society for Hyperthermic Oncology. Int J Hyperthermia 1996; 12: 3-20.
  • Emami B, Scott C, Ferez CA, Asbell S, Swift P, Grigsby P, Montesano A, Rubin P, Curran W, Delrowe J, Arastu H, Fu K, Monos E. Phase III study of interstitial thermoradiotherapy compared with interstitial radiotherapy alone in the treatment of recurrent or persistent human tumors. A prospectively controlled randomized study by the Radiation Therapy Group. Int J Radiat Oncol Biol Phys 1996; 34: 1097-104.
  • Overgaard J, Gonzalez Gonzalez D, Hulshof MC, Arcangeli G, Dahl O, Mella O, Bentzen SM. Randomised trial of hyperthermia as adjuvant to radiotherapy for recurrent or metastatic malignant melanoma. European Society for Hyperthermic Oncology. Lancet 1995; 345: 540-3.
  • Sneed PK, Stauffer PR, McDermott MW, Diederich CJ, Lamborn KR, Prados MD, Chang S, Weaver KA, Spry L, Malec MK, Lamb SA, Voss B, Davis RL, Wara WM, Larson DA, Phillips TL, Gutin PH. Survival benefit of hyperthermia in a prospective randomized trial of brachytherapy boost +/- hyperthermia for glioblastoma multiforme. Int J Radiat Oncol Biol Phys 1998; 40: 287-95.
  • van der Zee J, Gonzalez Gonzalez D, van Rhoon GC, van Dijk JD, van Putten WL, Hart AA. Comparison of radiotherapy alone with radiotherapy plus hyperthermia in locally advanced pelvic tumours: a prospective, randomised, multicentie trial. Dutch Deep Hyperthermia Group. Lancet 2000; 355: 1119-25.
  • Valdagni R, Amichetti M. Report of long-term follow-up in a randomized trial comparing radiation therapy and radiation therapy plus hyperthermia to metastatic lymph nodes in stage IV head and neck patients. Int J Radiat Oncol Biol Phys 1994; 28: 163-9.
  • Vernon CC, Hand JW, Field SB, Machin D, Whaley JB, van der Zee J, van Putten WL, van Rhoon GC, van Dijk JD, Gonzalez Gonzalez D, Liu FF, Goodman P, Sherar M. Radiotherapy with or without hyperthermia in the treatment of superficial localized breast cancer results from five randomized controlled trials. International Collaborative Hyperthermia Group. Int J Radiat Oncol Biol Phys 1996; 35: 731-44.
  • Robins HI, Co hen JD. Radiant heat systemic hyperthermia clinical trials. Adv Exp Med Biol 1990; 267: 189-96.
  • Wiedemann GJ, Robins HI, Katschinski DM, Mentzel M, van Heek R, Touhidi RR, Bucsky P, Gillis W, Feyerabend T, d'Oleire F, Freund C, Eleftheriadis S, Weiss C, Wagner T. [Clinical studies on combination of ifosfamide, carboplatin and etoposide (ICE) with whole body hyperthermia]. Medizinische Klinik 1996; 91: 279-83.
  • Matsuda H, Strebel FR, Kaneko T, Danhauser LL, Jenkins GN, Toyota N, Bull JM. Long duration-mild whole body hyperthermia of up to 12 hours in rats: feasibility, and efficacy on primary tumour and axillary lymph node metastases of a mammary adenocarcinoma: implications for adjuvant therapy. Int J Hyperthermia 1997; 13: 89-98.
  • Sakaguchi Y, Makino M, Kaneko T, Stephens LC, Strebel FR, Danhauser LL, Jenkins GN, Bull JM. Therapeutic efficacy of long duration-low temperature whole body hyperthermia when combined with tumor necrosis factor and carboplatin in rats. Cancer Res 1994; 54: 2223-7.
  • Page RL, Thrall DE, Dewhirst MW, Macy DW, George SL, McEntee MC, Heidner GL, Novotney CA, Alien SA, Withrow SJ. Phase I study of melphalan alone and melphalan plus whole body hyperthermia in dogs with malignant melanoma Int J Hyperthermia 1991; 7: 559-66.
  • Hauck ML, Price GS, Ogilvie GK, Johnson J, Gillette EL, Thrall DE, Dewhirst MW, Page RL. Phase I evaluation of mitoxantrone alone and combined with whole body hyperthermia in dogs with lymphoma. Int J Hyperthermia 1996; 12: 309-20.
  • Warner SL. Preliminary study of the effect of artificial fever upon hopeless tumor cases. Am J Roentgenol 1935; 33: 75-87.
  • Bull JM. Systemic hyperthermia: background and principles. In: Storm FK, ed. Hyperthermia in cancer therapy. Boston, MA: G. K. Hall Medical Publishers,1983; 401-5.
  • Pettigrew RT, Gait JM, Ludgate CM, Smith AN. Clinical effects of whole-body hyperthermia in advanced malignancy. Br Med J 1974; 4: 679-82.
  • Robins HI, Cohen JD, Schmitt CL, Tutsch KD, Feierabend C, Arzoomanian RZ, Albert D, d'Oleire F, Longo W, Heiss C. Phase I clinical trial of carboplatin and 41.8°C wholebody hyperthermia in cancer patients. J Clin Oncol 1993; 11: 1787-94.
  • Robins HI, D'Oleire F, Grosen E, Spriggs D. Rationale and clinical status of 41.8°C systemic hyperthermia tumor necrosis factor, and melphalan for neoplastic disease. Anticancer Res 1997; 17: 2891-4.
  • Sakaguchi Y, Stephens LC, Makino M, Kaneko T, Strebel FR, Danhauser LL, Jenkins GN, Bull JM. Apoptosis in tumors and normal tissues induced by whole body hyperthermia in rats. Cancer Res 1995; 55: 5459-64.
  • Burd R, Dziedzic TS, Xu Y, Caligiuri MA, Subjeck JR, Repasky EA. Tumor cell apoptosis, lymphocyte recruitment and tumor vascular changes are induced by low temperature, long duration (fever-like) whole body hyperthermia. J Cell Physiol 1998; 177: 137-47.
  • Repasky EA, Tims E, Pritchard M, Burd R. Characterization of mild whole-body hyperthermia protocols using human breast, ovarian, and colon tumors grown in severe combined immunodeficient mice. Infect Dis Obs Gynecol 1999; 7: 91-7.
  • Di YP, Repasky EA, Subjeck JR. Distribution of HSP70, protein kinase C, and spectrin is altered in lymphocytes during a fever-like hyperthermia exposure. J Cell Physiol 1997; 172: 44-54.
  • Wang XY, Ostberg JR, Repasky EA. Effect of fever-like whole-body hyperthermia on lymphocyte spectrin distribution, protein kinase C activity, and uropod formation. J Immunol 1999; 162: 3378-87.
  • Wang WC, Goldman LM, Schleider DM, Appenheimer MM, Subjeck JR, Repasky EA, Evans SS. Fever-range hyperthermia enhances L-selectin-dependent adhesion of lymphocytes to vascular endothelium. J Immunol 1998; 160: 961-9.
  • Evans SS, Wang W-C, Bain MD, Burd R, Ostberg JR, Repasky EA. Fever-range hyperthermia dynamically regulates lymphocyte delivery to high endothelial venules. Blood 2001:97:2727-33.
  • Evans SS, Schleider DM, Bowman LA, Francis ML, Kansas GS, Black JD. Dynamic association of L-selectin with the lymphocyte cytoskeletal matrix. J Immunol 1999; 162: 3615-24.
  • Evans SS, Bain MD, Wang WC. Fever-range hyperthermia stimulates a4ß7 integrindependent lymphocyte-endothelia adhesion. Int J Hyperthermia 2000; 16: 45-59.
  • Evans SS, Frey M, Schleider DM, Bruce RA, Wang WC, Repasky EA, Appenheimer MM. Leukocyte-endothelial cell interactions in tumor immunity. In: Mihich E, Croce C, eds. The Biology of Tumors. New York: Plenum Press, 1998; 273-86.
  • Butcher EC, Williams M, Youngman K, Rott L, Briskin M. Lymphocyte trafficking and regional immunity. Ad Immunol 1999; 72: 209-53.
  • Ostberg JR, Repasky EA. Comparison of the effects of two different whole body hyperthermia protocols on the distribution of murine leukocyte populations. Int J Hyperthermia 2000; 16: 29-43.
  • Nagel VLJ, Berry JM, Bull JMC. Cardiovascular safety of whole body hyperthermia (WBH) at 41.8°C and 40°C. In: Eighteenth Annual Meeting of the North American Hyperthermia Society, Philadelphia, PA, 1999.
  • Frey M, Appenheimer MM, Evans SS. Tyrosine kinase-dependent regulation of L-selectin expression through the Leu-13 signal transduction molecule: evidence for a protein kinase C-independent mechanism of L-selectin shedding. J Immunol 1997; 158: 5424-34.
  • Stewart JR, Gibbs FA, Jr. Hyperthermia in the treatment of cancer. Perspectives on its promise and its problems. Cancer 1984; 54: 2823-30.
  • Herman TS, Zukoski CF, Anderson RM, Hutter JJ, Blitt CD, Malone JM, Larson DF, Dean JC, Roth HB. Whole body hyperthermia and chemotherapy for treatment of patients with advanced, refractory malignancies. Cancer Treat Rep 1982; 66: 259-65.
  • Larkin JM, Edwards WS, Smith DE. Total body hyperthermia and preliminary results in human neoplasms. Surgical Forum 1976; 27: 121-3.
  • Wiedemann GJ, Robins HI, Katschinski DM, Mentzel M, d'Oleire F, Kutz M, Wagner T. Systemic hyperthermia and ICE chemotherapy for sarcoma patients: rationale and clinical status. Anticancer Res 1997; 17: 2899-902.
  • Wiedemann GJ, Robins HI, Gutsche S, Mentzel M, Decken M, Katschinski DM, Eleftheriadis S, Crahe R, Weiss C, Storer B, Wagner T. Ifosfamide, carboplatin and etoposide (ICE) combined with 41.8°C whole body hyperthermia in patients with refractory sarcoma. Eur J Cancer 1996; 32A: 888-92.
  • Robins HI, Katschinski DM, Longo W, Grasen E, Wilding G, Gil lis W, Kraemer C, Tiggelaar CL, Rushing D, Stewart JA, Spriggs D, Love R, Arzoomanian RZ, Feierabend C, Alberti D, Morgan K, Simon K, d'Olrire F. A pilot study of melphalan, tumor necrosis factor-alpha and 41.8°C whole-body hyperthermia Cancer Chemother Pharmacol 1999; 43: 409-14.
  • Ostberg JR, Repasky EA. Use of mild, whole body hyperthermia in cancer therapy. Immunol Invest 2000; 29: 139-42.

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