Advanced search
Publication Cover
International Journal of Hyperthermia Volume 19, 2003 - Issue 4
Submit an article Journal homepage
138
Views
8
CrossRef citations to date
0
Altmetric
Research Article

Heat- and 4-hydroperoxy-ifosfamide-induced apoptosis in B cell precursor leukaemias

C. Mauz-Körholz Division of Pediatric Hematology and Oncology, Department of Pediatrics, University of Leipzig Medical Center, Oststr. 21-25, D-04317 Leipzig, Germany
,
S. Dietzsch Division of Pediatric Hematology and Oncology, Department of Pediatrics, University of Leipzig Medical Center, Oststr. 21-25, D-04317 Leipzig, Germany
,
U. Banning Division of Pediatric Hematology and Oncology, Department of Pediatrics, University of Leipzig Medical Center, Oststr. 21-25, D-04317 Leipzig, Germany
,
R.-B. Tröbs Department of Pediatric Surgery, University of Leipzig Medical Center, Oststr. 21-25, D-04317 Leipzig, Germany
&
D. Körholz Division of Pediatric Hematology and Oncology, Department of Pediatrics, University of Leipzig Medical Center, Oststr. 21-25, D-04317 Leipzig, Germany
Pages 444-460 | Published online: 09 Jul 2009

  • Schrappe M, Reiter A, Zimmermann M, Harbott J, Ludwig WD, Henze G, Gadner H, Odenwald E, Riehm H. Long-term results of four consecutive trials in childhood ALL performed by the ALL-BFM study group from 1981 to 1995. Berlin-Frankfurt-Münster. Leukemia 2000; 14: 2205-22.
  • Harms DO, Janka-Schaub GE. Co-operative study group for childhood acute lymphoblastic leukemia (COALL): long-term follow-up of trials 82, 85, 89 and 92. Leukemia 2000; 14: 2234-9.
  • Pui CH. Acute lymphoblastic leukemia in children. Curr Opin Oncol 2000; 12: 3-12.
  • Arico M, Valsecchi MG, Camitta B, Schrappe M, Chessells J, Baruchel A, Gaynon P, Silverman L, Janka-Schaub G, Kamps W, Pui CH, Masera G. Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemia. N Engl J Med 2000; 342: 998-1006.
  • Bührer C, Hartmann R, Fengler R, Rath B, Schrappe M, Janka-Schaub G, Henze G. Peripheral blast counts at diagnosis of late isolated bone marrow relapse for childhood acute lymphoblastic leukemia predict response to chemotherapy and outcome. BerlinFrankfurt-Münster Relapse Study group. J Clin Oncol 1996; 14: 2812-7.
  • Seeger K, Kreuzer K-A, Lass U, Taube T, Buchwald D, Eckert C, Körner G, Schmidt CA, Henze G. Molecular quantification of response to therapy and remission status in TEL-AMLI-positive childhood ALL by real-time reverse transcription polymerase chain reaction. Cancer Res 2001; 61: 2517-22.
  • Niethammer D, Klingebiel T, Ebell W, Henze G, Paolucci P, Riehm H. Which children do benefit from bone marrow transplant? The EBMT paediatric diseases working party. Bone Marrow Transplant 1996; 18 (suppl 2): 43-6.
  • Klumper E, Pieters R, Veerman AJ, Huismans DR, Loonen AH, Hahlen K, Kaspers GJ, van Wering G. In vitro cellular drug resistance in children with relapsed/refractory lymphoblastic leukemia. Blood 1995; 86: 3861-8.
  • Kutz ME, Mulkerin DL, Wiedemann GJ, Katschinski DM, Robins HI. In vitro studies of the hyperthermic enhancement of activated ifosfamide (4-hydroperoxy-ifosfamide) and glucose isophosphoramide mustard. Cancer Chemother Pharmacol 1997: 40: 167-71.
  • Robins HI, Neville AJ, Cohen JD. Whole body hyperthermia: biological, and clinical aspects. In: Gautherie M, ed. Clinical thermology. Berlin, Heidelberg: Springer-Verlag, 1992; 64.
  • FaIk MH, Issels RD. Hyperthermia in oncology. Int J Hyperthermia 2001; 17: 1-18.
  • Wessalowski R, Kruck H, Pape H, Kahn T, Willers R, Göbel U. Hyperthermia for the treatment of patients with malignant germ cell tumors: a phase I/II study in ten children and adolescents with recurrent or refractory tumors. Cancer 1998; 82: 793-800.
  • Wessalowski R, Willnow U, Jürgens H, Dehnen H, Göbel U. Total body hyperthermia in combination with etoposide and melphalan in a child with acute myelomonocytic leukemia. Med Pediatr Oncol 1994; 22: 61-5.
  • Wiedemann GJ, d'Oleire F, Knop E, Eleftheriadis S, Bucsky P, Feddersen S, Klouche M, Geisler J. Ifosfamide and carboplatin combined with 41.8 degrees C whole-body hyperthermia in patients with refractory sarcoma and malignant teratoma. Cancer Res 1994; 15: 5346-50.
  • Wendtner C, Abdel-Rahman S, Baumert J, FaIk MH, Krych M, Santl M, Hiddemann W, Isrels RD. Treatment of primary, recurrent or inadequately resected high-risk-soft-tissue sarcomas (STS) of adults: results of a phase II pilot study (RHT-95) of neoadjuvant chemotherapy combined with regional hyperthermia. Eur J Cancer 2001; 37: 1609-16.
  • Bakhshandeh A, Bruns I, Eberhardt K, Wiedemann GJ. Chemotherapy in combination with whole-body hyperthermia in advanced malignant pleural mesothelioma. Dtsch Med Wochenschr 2000; 17: 317-9.
  • Schwartz PS, Waxman DJ. Cyclophosphamide induces caspase-9-dependent apoptosis in 9L tumor cells. MoI Pharmacol 2001; 60: 1268-79.
  • Takasu T, Lyons JC, Park HJ, Song CW. Apoptosis and perturbation of cell cycle progression in acidic environment after hyperthermia. Cancer Res 1998; 58: 2504-8.
  • Katschinski DM, Robins HI, Schad M, Frede S, Fandrey J. Role of tumor necrosis factor a in hyperthermia-induced apoptosis of human leukemia cells. Cancer Res 1999; 59: 340410.
  • German AM, Heavey B, Creagh E, Cotter TG, Samali A. Antioxidant-mediated inhibition of the heat shock response leads to apoptosis. FEBS Lett 1999; 445: 98-102.
  • Falcieri E, Luchetti F, Burattini S, Canonico B, Santi S, Papa S. Lineage-related sensitivity to apoptosis in human tumor cells undergoing hyperthermia. Histochem Cell Biol 2000; 113: 135-44.
  • Okamoto K, Shinoura N, Egawa N, Asai A, Kirino T, Shibasaki F, Slinfara N. Adenovirus-mediated transfer of p53 augments hyperthermia-induced apoptosis in U251 glioma cells. Int J Radiat Oncol Biol Phys 2001; 50: 525-6.
  • Hermisson M, Wagenknecht B, Wolburg H, Glaser T, Dichgans J, Weller M. Sensitization to CD95 ligand-induced apoptosis in human glioma cells by hyperthermia involves enhanced cytochrome c release. Oncogene 2000; 19: 2338-45.
  • Arends J. Effects of a combined thermochemotherapy on markers of apoptosis, differentiation and adhesion in the human mammary carcinoma MX-I. Ann Anat 2000; 182: 33947.
  • Körholz D, Banning U, Bönig H, Grewe M, Schneider M, Mauz-Körholz C, KleinVelane A, Krutmann J, Burdach S. The role of interleukin 10 (IL-10) in IL-15-mediated T cell responses. Blood 1997; 90: 4513-21.
  • Barry MA, Behnke CA, Eastman A. Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia. Biochem Pharmacol 1990; 40: 2353-62.
  • Miller TM, Moulder KL, Knudson CM, Creedon DJ, Deshmukh M, Korsmeyer SJ, Johnson EM. Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death. / Cell Biol 1997; 139:20517.
  • Xiang J, Chao DT, Korsmeyer SJ. Bax-induced cell death may not require interleukin 1beta-converting enzyme-like proteases. Proc Natl Acad Sd USA 1996; 93: 14559-63.
  • Stahnke K, Fulda S, Friesen C, Strauß G, Debatin KM. Activation of apoptosis pathways in peripheral blood lymphocytes by in vivo chemotherapy. Blood 2001; 98: 3066-73.
  • Herr I, Debatin KM. Cellular stress response and apoptosis in cancer therapy. Blood 2001; 98: 2603-14.
  • Boldin MP, Goncharov TM, Goltsev YV, Wallach D. Involvement of MACH, a novel MORTl/FADD-interacting protein in Fas/APO-I and TNF receptor-induced cell death. Cell 1996; 85: 803-15.
  • Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES, Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997; 91: 479-89.
  • Cohen GM. Caspases: the executioners of apoptosis. Biochem J 1997; 326: 1-16.
  • Katschinski DM, Boos K, Schindler SG, Fandrey J. Pivotal role of reactive oxygen species as intracellular mediators of hyperthermia-induced apoptosis. / Biol Chem 2000; 275: 21094-8.
  • Kobayashi D, Watanabe N, Yamauchi N, Okamoto T, Tsuji N, Sasaki H, Sato T, Niitsuu Y. Heat-induced apoptosis via caspase-3 activation in tumour cells carrying mutant p53. Int J Hyperthermia 2000; 16: 471-80.
  • Friesen C, Herr I, Krammer PH, Debatin K-M. Involvement of the CD95 (APO-1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nat Med 1996; 2: 5747.
  • Becker R, Ritter A, Eichhorn U, Lips J, Bertram B, Wiessler M, Zdzienicka MZ, Kaina B. Induction of DNA breaks and apoptosis in crosslink-hypersensitive V79 cells by the cytostatic drug beta-D-glucosyl-ifosfamide mustard. Br J Cancer 2002; 86: 130-5.
  • Karle P, Renner M, Salmons B, Günzburg WH. Necrotic, rather than apoptotic, cell death caused by cytochrome P450-activated ifosfamide. Cancer Gene Ther 2001; 8: 22030.
  • Poyet JL, Srinivasula SM, Tnani M, Razmara M, Fernandes-Alnemri T, Alnemri ES. Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1. J Biol Chem 2001; 276: 28309-13.
  • Geddes BJ, Wang L, Huang WJ, Lavellee M, Manji GA, Brown M, Jurman M, Cao J, Morgenstern J, Merriam S, Glucksmann MA, Distefano PS, Bertin J. Human CARD 12 is a novel CED4/Apaf-1 family member that induces apoptosis. Biochem Biophys Res Commun 2001; 77: 77-82.
  • Ueki T, Takeuchi T, Nishimatsu H, Kajiwara T, Moriyama N, Narita Y, Kawabe K, Ueki K, Kistamura T.. Silencing of the caspase-1 gene occurs in murine and human renal cancer cells and causes solid tumor growth in vivo. Int J Cancer 2001; 91: 673-9.
  • Muguruma K, Nakata B, Yanagawa K, Nitta A, Yashiro M, Onoda N, Mirakawa K Caspase-1 activity as a possible predictor of apoptosis induced by cisplatin in gastric cancer cells. Int J MoI Med 2000; 6: 553-7.
  • Hisahara S, Takano R, Shoji S, Okano H, Miura M. Role of caspase-1 subfamily in cytotoxic cytokine-induced oligodendrocyte cell death. / Neural Transm Suppl 2000; 58: 135-42.
  • Hermisson M, Weller M. Hyperthermia enhanced chemosensitivity of human malignant glioma cells. Anticancer Res 2000; 20: 1819-23.
  • Othman T, Goto S, Lee J-B, Taimura A, Matsumoto T, Kosaka M. Hyperthermic enhancement of the apoptotic and antiproliferative activities of paclitaxel. Pharmacology 2001; 62: 208-12.
  • Sarosy G. Ifosfamide-pharmacologic overview. Semin Oncol 1989; 16 (suppl 3): 2-8.
  • Schmid H, von Sehende U, Hartmann R, Borgmann A, Henze G. Allogeneic BMT vs. chemotherapy in late bone marrow relapsed childhood non-T/non-B ALL: results of BFM ALL relapse studies. BFM relapse study group. Bone Marrow Transplant 1996; 18 (suppl 2): 28-30.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.