319
Views
30
CrossRef citations to date
0
Altmetric
Original Article

Whole-body hyperthermia in the scope of von Ardenne's systemic cancer multistep therapy (sCMT) combined with chemotherapy in patients with metastatic colorectal cancer: a phase I/II study

, , , , , , , , & show all
Pages 317-333 | Received 16 Mar 2003, Accepted 01 Oct 2003, Published online: 09 Jul 2009

References

  • Holen KD, Saltz LB. New therapies, new directions: advances in the systemic treatment of metastatic colorectal cancer. Lancet Oncol 2001; 2: 290–7.
  • Tebbutt NC, Cattell E, Midgley R, Cunningham D, Kerr D. Systemic treatment of colorectal cancer. Eur J Cancer 2002; 38: 1000–15.
  • Richards F, II, Case LD, White DR, Muss HB, Spurr CL, Jackson DV, Cooper MR, Zekan P, Cruz J, Stuart JJ, et al. Combination chemotherapy (5-fluorouracil, methyl-CCNU, mitomycin C) versus 5-fluorouracil alone for advanced previously untreated color-ectal carcinoma. A phase III study of the Piedmont Oncology Association. J Clin Oncol 1986; 4: 565–70.
  • Ross P, Norman A, Cunningham D, Webb A, Iveson T, Padhani A, Prendiville J, Watson M, Massey A, Popescu R, Oates J. A prospective randomised trial of protracted venous infusion 5-fluorouracil with or without mitomycin C in advanced colorectal cancer. Ann Oncol 1997; 8: 995–1001.
  • Dahl O. Interaction of heat and drugs in vitro and in vivo. In: Vernon CC, ed. Therrnoradiotherapy and Therrnochernotherapy. Berlin: Springer, 1995; 103–21.
  • Hahn GM, Li GC. Interactions of hyperthermia and drugs: treatments and probes. Natl Cancer Inst Monogr 1982; 61: 217–21.
  • Witkamp AJ, de Bree E, Kaag MM, Boot H, Beijnen JH, van Slooten GW, van Coevorden F, Zoetmulder FA. Extensive cytoreductive surgery followed by intra-opera-five hyperthermic intraperitoneal chemotherapy with mitomycin-C in patients with peri-toneal carcinomatosis of colorectal origin. Eur J Cancer 2001; 37: 979–84.
  • Atanackovic D, Nierhaus A, Neumeier M, Hossfeld DK, Hegewisch-Becker S. 41.8 degrees C whole body hyperthermia as an adjunct to chemotherapy induces prolonged T cell activation in patients with various malignant diseases. Cancer Irnrnunol Immunother 2002; 51: 603–13.
  • Hildebrandt B, Wust P, Ahlers O, Dieing A, Sreenivasa G, Kerner T, Felix R, Riess H. The cellular and molecular basis of hyperthermia. Crit Rev Oncol Hernatol 2002; 43: 33–56.
  • Robins HI, Kutz M, Wiedemann GJ, Katschinski DM, Paul D, Grosen E, Tiggelaar CL, Spriggs D, Gillis W, D'Oleire F. Cytokine induction by 41.8 degrees C whole body hyperthermia. Cancer Lett 1995; 97: 195–201.
  • Falk MH, Issels RD. Hyperthermia in oncology. Int j Hyperthermia 2001; 17: 1–18.
  • Wust P, Hildebrandt B, Sreenivasa G, Rau B, Gellermann J, Riess H, Schlag P. Hyperthermia in combined treatment of cancer. Lancet Oncol 2002; 3: 487–97.
  • Kerner T, Deja M, Gerlach H, Ahlers O, Löffel J, Wust P, Hildebrandt B, Felix R, Riess H. Whole-body hyperthermiaa secure procedure for patients with various malignancies?Intensive Care Med 1999; 25: 959–65.
  • Robins HI, Dennis WH, Neville AJ, Shecterie LM, Martin PA, Grossmann J, Davis TE, Neville SR, Gillis WK, Rusy BF. A nontoxic system for 41.8°C whole body hyperthermia: results of a phase I study using a radiant heat device. Cancer Res 1985; 45: 3937–44.
  • Robins HL, Cohen JD, Schmitt CL, Tutsch KD, Feierabend C, Arzoomanian RZ, Alberti D, D'Oleire F, Longo W, Heiss C, Rushing D, Love R, Spriggs D. Phase I clinical trial of carboplatin and 41.8°C whole-body hyperthermia in cancer patients. J Clin Oncol 1993; 9: 1787–94.
  • Bakhshandeh A, Bruns I, Traynor A, Robins HI, Eberhardt K, Demedts A, Kaukel E, Koschel G, Gatzemeier U, Kohlmann T, Dalhoff K, Ehlers EM, Gruber Y, Zumschlinge R, Hegewisch-Becker S, Peters SO, Wiedemann GJ. Ifosfamide, carboplatin and etoposide combined with 41.8 degrees C whole body hyperthermia for malignant pleural mesothelioma. Lung Cancer 2003; 39: 339–45.
  • Hegewisch-Becker S, Gruber Y, Corovic A, Pichlmeier U, Atanackovic D, Nierhaus A, Hossfeld D. Whole-body hyperthermia (41.8 degrees C) combined with bimonthly oxali-platin, high-dose leucovorin and 5-fluorouracil 48-hour continuous infusion in pretreated metastatic colorectal cancer: a phase II study. Ann Oncol 2002; 13: 1197–204.
  • Strobl B, Janni W, Rjosk D, Rack BK, Kornya L, Bakhshandeh-Bath A, Hegewisch-Becker S, Hildebrandt B, Sommer HL. Chemotherapy with carboplatin/ifosfamide combined with whole body hyperthermia in recurrent ovarian cancerresults of a phase IIstudy (Dolphin-I-study). J. Clin Oncol 2002; 19:A2523
  • Westermann AM, Grosen EA, Katschinski DM, Jager D, Rietbroek R, Schink JC, Tiggelaar CL, Jager E, Zum Vorde sive Vording P, Neuman A, Knuth A, Van Dijk JD, Wiedemann GJ, Robins HI. A pilot study of whole body hyperthermia and carbo-platin in platinum-resistant ovarian cancer. Eur J Cancer 2001; 37: 1111–17.
  • Westermann AM, Wiedemann GJ, Jager E, Jager D, Katschinski DM, Knuth A, Vorde Sive Vording PZ, Van Dijk JD, Finet J, Neumann A, Longo W, Bakhshandeh A, Tiggelaar CL, Gillis W, Bailey H, Peters SO, Robins HI. A Systemic Hyperthermia Oncologic Working Group trial. Ifosfamide, carboplatin, and etoposide combined with 41.8 degrees C whole-body hyperthermia for metastatic soft tissue sarcoma. Oncology 2003; 64: 312–21.
  • Von Ardenne M. Principles and concept 1993 of the systemic cancer multistep therapy (sCMT). Strahlenther Onkol 1994; 170: 581–9.
  • Wust P, Riess H, Hildebrandt B, Loffel J, Deja M, Ahlers O, Kener T, Ardenne A, Felix R. Utilizing the Iratherm-2000 infrared system for whole-body hyperthermia at 42°Ca feasibility study. Int J Hypertherrnia 2000; 16: 325–39.
  • Kerner T, Deja M, Ahlers O, Hildebrandt B, Dieing A, Riess H, Wust P, Gerlach H. Monitoring arterial blood pressure during whole body hyperthermia. Acta Anaesthesiol Scand 2002; 46: 561–6.
  • Kerner T, Hildebrandt B, Ahlers O, Deja M, Riess H, Draeger J, Wust P, Gerlach H. Anaesthesiological experiences in whole-body hyperthermia. Int J Hypertherrnia 2002; 1–12.
  • Kreyszig E. Statistical Methods and their Applications. Goettingen: Vandenhoeck & Ruprecht, 1972 [in German].
  • Robins HI, Rushing D, Kutz M, Tutsch KD, Tiggelaar CL, Paul D, Spriggs D, Kraemer C, Gillis W, Feierabend C, Arzoomanian RZ, Longo W, Alberti D, d'Oliere F, Qu RP, Wilding G, Steart JA. Phase I clinical trial of melphalan and 41.8°C whole-body hyperthermia in cancer patients. J Clin Oncol 1997; 15: 158–64.
  • Hildebrandt B. Clinical trials on whole-body hyperthermia combined with chemotherapy. Onkologie 2002; 25: A912.
  • Pereira Arias AM, Wester JP, Blankendaal M, Schilthuis MS, Kuijper EJ, Rademaker BM, Stoutenbeek C, Rietbroek R. Multiple organ dysfunction syndrome induced by whole-body hyperthermia and polychemotherapy in a patient with disseminated leiomyosarcoma of the uterus. Intensive Care Med 1999; 25: 1013–16.
  • Wiedemann GJ, Robins HI, Gutsche S, Mentzel M, Deeken M, Katschinsky DM, Eleftheriadis S, Crahe R, Weiss C, Storer B, Wagner T. Ifosfamide, carboplatin and etoposide (ICE) combined with 41.8°C whole body hyperthermia in patients with refrac-tory sarcoma. Eur J Cancer 1996; 32A: 888–92.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.