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Original Article

Effects of hyperthermia on the peripheral nervous system: a review

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Pages 371-391 | Received 21 Jul 2003, Published online: 16 Apr 2010

References

  • Overgaard J, Gonzalez Gonzalez D, Hulshof MC, Arcangeli G, Dahl O, Mella O, Bentzen SM. Randomised trial of hyperthermia as adjuvant to radiotherapy for recurrent or metastatic malignant melanoma. European Society for Hyperthermic Oncology. Lancet 1995; 345: 540–3.
  • Vernon CC, Hand JW, Field SB, Machin D, Whaley JB, van der Zee J, van Putten WL, van Rhoon GC, Van Dijk JD, Gonzalez Gonzalez D, Liu FF, Goodman P, Sherar M. Radiotherapy with or without hyperthermia in the treatment of superficial localized breast cancer: results from five randomized controlled trials. International Collaborative Hyperthermia Group. Int J Radiat Oncol Biol Phys 1996; 35: 731–44.
  • Van der Zee J, Gonzalez Gonzalez D, van Rhoon GC, Van Dijk JD, van Putten WL, Hart AA. Comparison of radiotherapy alone with radiotherapy plus hyperthermia in locally advanced pelvic tumours: a prospective, randomised, multicentre trial. Dutch Deep Hyperthermia Group. Lancet 2000; 355: 1119–25.
  • Kim JR, Johnson JL. The effects of hyperthermia on fast axoplasmic transport in rat sensory fibers. Brain Res 1982; 237: 215–21.
  • Klumpp D, Zimmermann M. Irreversible differential block of A- and C-fibres following local nerve heating in the cat. J Physiol 1980; 298: 471–82.
  • Xu D, Pollock M. Experimental nerve thermal injury. Brain 1994; 117: 375–84.
  • Lele PP. Effects of focussed ultrasonic radiation on peripheral nerve, with observations on local heating. Exp Neurol 1963; 8: 47–83.
  • Brodkey JS, Miyazaki Y, Ervin FR, Mark VH. Reversible heat lesions with radiofre-quency current. J Neurosurg 1964; 21: 49–53.
  • Eliasson SG, Monafo WW, Nussbaum G, Olsen L. Differential effects of in vitro heating on rat sciatic nerve branches and spinal nerve roots. Exp Neurol 1986; 93: 57–66.
  • Eliasson SG, Monafo WW, Meyr D. Potassium ion channel blockade restores conduction in heat-injured nerve and spinal nerve roots. Exp Neurol 1986; 93: 128–37.
  • De Vrind HH, Wondergem J, Haveman J. Hyperthermia-induced damage to rat sciatic nerve assessed in vivo with functional methods and with electrophysiology. J Neurosci Methods 1992; 45: 165–74.
  • Hoogeveen JF, Troost D, Wondergem J, van der Kracht AH, Haveman J. Hyperthermic injury versus crush injury in the rat sciatic nerve: a comparative functional, histopatho-logical and morphometrical study. J Neurol Sci 1992; 108: 55–64.
  • Hoogeveen JF, Troost D, van der Kracht AH, Wondergem J, Haveman J, Gonzalez Gonzalez D. Ultrastructural changes in the rat sciatic nerve after local hyperthermia. Int J Hyperthermia 1993; 9: 723–30.
  • Vujaskovic Z, Gillette SM, Powers BE, Larue SM, Gillette EL, Borak TB, Scott RJ, Ryan TP, Colacchio TA. Effects of intraoperative hyperthermia on peripheral nerves: neurolo-gical and electrophysiological studies. Int J Hyperthermia 1994; 10: 41–9.
  • Wondergem J, Haveman J, Rusman V, Sminia P, Van Dijk JD. Effects of local hyper-thermia on the motor function of the rat sciatic nerve. Int J Radiat Biol 1988; 53: 429–38.
  • Vujaskovic Z, McChesney GS, Powers BE, Gillette EL, Scott RJ, Whalen RL, Ryan TP, Colacchio TA. Effects of intraoperative hyperthermia on canine sciatic nerve: histopatho-logic and morphometric studies. Int J Hyperthermia 1994; 10: 845–55.
  • Hoogeveen JF, van der Kracht AH, Wondergem J, Gonzalez Gonzalez D, Haveman J. Influence of cisplatin on the sensitivity of the rat sciatic nerve to local hyperthermia. Neurotoxicology 1993; 14: 1–7.
  • De Vrind HH, van Dam WM, Wondergem J, Haveman J. Latent X-ray damage in the rat sciatic nerve results in delay in functional recovery after a heat treatment. Int J Radiat Biol 1993; 63: 83–9.
  • Haveman J, Wondergem J, van Dam WM, Van der Kracht AHW. Irradiation of the rat sciatic nerve leads to delayed recovery from function loss after heat treatment or mechan-ical damage. Neurosci Res Comm 1994; 14: 1–7.
  • Vujaskovic Z, Gillette SM, Powers BE, Stukel TA, Larue SM, Gillette EL, Borak TB, Scott RJ, Weiss J, Colacchio TA. Effects of intraoperative irradiation and intraoperative hyperthermia on canine sciatic nerve: neurologic and electrophysiologic study. Int J Radiat Oncol Biol Phys 1996; 34: 125–31.
  • Vujaskovic Z, Powers BE, Paardekoper G, Gillette SM, Gillette EL, Colacchio TA. Effects of intraoperative irradiation (IORT) and intraoperative hyperthermia (IOHT) on canine sciatic nerve: histopathological and morphometric studies. Int J Radiat Oncol Biol Phys 1999; 43: 1103–9.
  • Dewhirst MW, Sim DA. Estimation of therapeutic gain in clinical trials involving hyperthermia and radiotherapy. Int J Hypertherrnia 1986; 2: 165–78.
  • Davis FA, Jacobson S. Altered thermal sensitivity in injured and demyelinated nerve. A possible model of temperature effects in multiple sclerosis. J Neurol Neurosurg Psychiatry 1971; 34: 551–61.
  • Rasminsky M. The effects of temperature on conduction in demyelinated single nerve fibers. Arch Neurol 1973; 28: 287–92.
  • Berger JR, Sheremata WA. Persistent neurological deficit precipitated by hot bath test in multiple sclerosis. J Am Med Assoc 1983; 249: 1751–3.
  • Hoogeveen JF, Van der Kracht AHW, Wondergem J, Haveman J. Effects of local hyperthermia on the sensitivity of rat sciatic nerve from diabetic rats. Neurosci Res Comm 1993; 12: 63–70.
  • De Vrind HH, Haveman J, Wondergem J. Induction of thermal tolerance of rat sciatic nerve by mild hyperthermia. Int J Radiat Biol 1991; 59: 251–7.
  • Hoogeveen JF, van der Kracht AH, Wondergem J, Haveman J. Heat shock proteins (HSP-72 kD) in thermotolerant rat sciatic nerves. Int J Hypertherrnia 1993; 9: 361–8.
  • Kregel KC, Wall PT, Gisolfi CV. Peripheral vascular responses to hyperthermia in the rat. J Appl Physiol 1988; 64: 2582–8.
  • Kenney MJ, Barney CC, Hirai T, Gisolfi CV. Sympathetic nerve responses to hyper-thermia in the anesthetized rat. J Appl Physiol 1995; 78: 881–9.
  • Boulant JA, Bignall KE. Hypothalamic neuronal responses to peripheral and deep-body temperatures. Am J Physiol 1973; 225: 1371–4.
  • Kregel KC, Johnson DG, Tipton CM, Seals DR. Arterial baroreceptor reflex modulation of sympathetic-cardiovascular adjustments to heat stress. Hypertension 1990; 15: 497–504.
  • Kregel KC, Gisolfi CV. Circulatory responses to heat after celiac ganglionectomy or adrenal demedullation. J Appl Physiol 1989; 66: 1359–63.
  • Gisolfi CV, Matthes RD, Kregel KC, Oppliger R. Splanchnic sympathetic nerve activity and circulating catecholamines in the hyperthermic rat. J Appl Physiol 1991; 70: 1821–6.
  • Franken NA, de Vrind HH, Sminia P, Haveman J, Troost D, Gonzalez Gonzalez D. Neurological complications after 434 MHz microwave hyperthermia of the rat lumbar region including the spinal cord. Int J Radiat Biol 1992; 62: 229–38.
  • Sminia P, van der Zee J, Wondergem J, Haveman J. Effect of hyperthermia on the central nervous system: a review. Int J Hypertherrnia 1994; 10: 1–30.
  • Uhthoff W. Untersuchungen fiber die bei der multiplen Herdsklerose vorkommende Augendstörungen. Arch Psychiat Nervenkr 1890; 21: 55–116.
  • Guthrie TC, Nelson DA. Influence of temperature changes on multiple sclerosis: critical review of mechanisms and research potential. J Neurol Sci 1995; 129: 1–8.
  • Henke AF, Cohle SD, Cottingham SL. Fatal hyperthermia secondary to sunbathing in a patient with multiple sclerosis. Am J Forensic Med Pathol 2000; 21: 204–6.
  • Kohlmeier RE, DiMaio VJ, Kagan-Hallet K. Fatal hyperthermia in hot baths in indivi-duals with multiple sclerosis. Am J Forensic Med Pathol 2000; 21: 201–3.
  • Chaudhry V, Crawford TO, DeRossett SE. Thermal sensitivity in demyelinating neuro-pathy. Muscle Nerve 1993; 16: 301–6.
  • Perez CA, Emami B, Nussbaum GH. Regional (deep) heating, clinical studies in progress. Front Radiat Ther Oncol 1984; 18: 108–25.
  • Pilepich MV, Myerson RJ, Emami BN, Perez CA, Straube W, Von Gerichten D. Regional hyperthermiaassessment of tolerance to treatment. Int J Radiat Oncol Biol Phys 1988;14: 347–52.
  • Issels RD, Prenninger SW, Nagele A, Boehm E, Sauer H, Jauch KW, Denecke H, Berger H, Peter K, Wilmanns W. Ifosfamide plus etoposide combined with regional hyperthermia in patients with locally advanced sarcomas: a phase II study. J Clin Oncol 1990; 8: 1818–29.
  • Emami B, Myerson RJ, Scott C, Gibbs F, Lee C, Perez CA. Phase I/II study, combination of radiotherapy and hyperthermia in patients with deep-seated malignant tumors: report of a pilot study by the Radiation Therapy Oncology Group. Int J Radiat Oncol Biol Phys 1991; 20: 73–9.
  • Ben Yosef R, Sullivan DM, Kapp DS. Peripheral neuropathy and myonecrosis following hyperthermia and radiation therapy for recurrent prostatic cancer: correlation of damage with predicted SAR pattern. Int J Hypertherrnia 1992; 8: 173–85.
  • Scott RS, Clay L, Storey KV, Johnson RJ. Transient microwave induced neurosensory reactions during superficial hyperthermia treatment. Int J Radiat Oncol Biol Phys 1985; 11: 561–6.
  • Scott RS, Del Rowe JD. A transient hypotensive episode (Bezold-Jarisch effect) occurring in a patient treated with microwave hyperthermia. Am J Clin Oncol 1986; 9: 170–2.
  • Minor DR, Allen RE, Alberts D, Peng YM, Tardelli G, Hutchinson J. A clinical and pharmacokinetic study of isolated limb perfusion with heat and melphalan for melanoma. Cancer 1985; 55: 2638–44.
  • Lejeune FJ, Lienard D, el Douaihy M, Seyedi JV, Ewalenko P. Results of 206 isolated limb perfusions for malignant melanoma. Eur J Surg Oncol 1989; 15: 510–19.
  • Shiu MH, Knapper WH, Fortner JG, Yeh S, Horowitz G, Schnog J, Guerra J, Gould-Rossbach P, Ray C. Regional isolated limb perfusion of melanoma intransit metastases using mechlorethamine (nitrogen mustard). J Clin Oncol 1986; 4: 1819–26.
  • Busse O, Aigner K, Wilimzig H. Peripheral nerve damage following isolated extremity perfusion with cis-platinum. Recent Results Cancer Res 1983; 86: 264–7.
  • Jansen W, Haveman J. Histopathological changes in the skin and subcutaneous tissues of mouse legs after treatment with hyperthermia. Pathol Res Pract 1990; 186: 247–53.
  • Van der Zee J, Kroon BB, Nieweg OE, van de Merwe SA, Kampinga HH. Rationale for different approaches to combined melphalan and hyperthermia in regional isolated perfusion. Eur J Cancer 1997; 33: 1546–50.
  • Kroon BBR, Klaase JM, van de Merwe SA, van Dongen JA, van der Zee J. Results of a double perfusion schedule using high-dose hyperthermia and melphalan sequentially for recurrent melanoma of the limbs: a pilot study. Regional Cancer Treatment 1992; 4: 305–8.
  • Kerner T, Hildebrandt B, Ahlers O, Deja M, Riess H, Draeger J, Wust P, Gerlach H. Anaesthesiological experiences with whole body hyperthermia. Int J Hypertherrnia 2003; 19: 1–12.
  • Bull JM, Lees D, Schuette W, Whang-Peng J, Smith R, Bynum G, Atkinson ER, Gottdiener JS, Gralnick HR, Shawker TH, DeVita VT, Jr. Whole body hyperthermia: a phase-I trial of a potential adjuvant to chemotherapy. Ann Intern Med 1979; 90: 317–23.
  • Barlogie B, Corry PM, Yip E, Lippman L, Johnston DA, Khalil K, Tenczynski TF, Reilly E, Lawson R, Dosik G, Rigor B, Hankenson R, Freireich EJ. Total-body hyperthermia with and without chemotherapy for advanced human neoplasms. Cancer Res 1979; 39: 1481–9.
  • Selker RG, Jacobs SA, Stoller R, Kristofik M, Randall M. On the limits of human tolerance to whole body hyperthermia and simultaneous chemotherapy. Radiat Res 1983; 94: 550.
  • Gerad H, van Echo DA, Whitacre M, Ashman M, Helrich M, Foy J, Ostrow S, Wiernik PH, Aisner J. Doxorubicin, cyclophosphamide, and whole body hyperthermia for treat-ment of advanced soft tissue sarcoma. Cancer 1984; 53: 2585–91.
  • Koga S, Maeta M, Shimizu N, Osaki Y, Hamazoe R, Oda M, Karino T, Yamane T. Clinical effects of total-body hyperthermia combined with anticancer chemotherapy for far-advanced gastrointestinal cancer. Cancer 1985; 55: 1641–7.
  • Adam AM, Hughes RA, Payan J, McColl I. Peripheral neuropathy and hyperthermia. Lancet 1987; i: 1270–1.
  • Levin W, Blair RM. Pettigrew technique of inducing whole-body hyperthermia. Natl Cancer Inst Monogr 1982; 61: 377–9.
  • Sasaki M, Ide C. Demyelination and remyelination in the dorsal funiculus of the rat spinal cord after heat injury. J Neurocytol 1989; 18: 225–39.
  • Hermanek P. Tierexperirnentelle Untersuchungen zur hypertherrnen Zytostatika perfusion unter dern besonderen Aspekt der Scheidigung des peripheren Nerven. Erlangen-Niirnberg: Medical Faculty of the Friedrich Alexander Universität, 1981.
  • Nukada H, Dyck PI Microsphere embolization of nerve capillaries and fiber degenera-tion. Am J Pathol 1984; 115: 275–87.
  • Nukada H, Dyck PI Acute ischemia causes axonal stasis, swelling, attenuation, and secondary demyelination. Ann Neurol 1987; 22: 311–18.
  • Lees DE, Kim YD, Bull JM, Whang-Peng J, Schuette W, Smith R, Macnamara TE. Anesthetic management of whole-body hyperthermia for the treatment of cancer. Anesthesiology 1980; 52: 418–28.
  • Kettelhack C, Kraus T, Hupp T, Manner M, Schlag P. Hyperthermic limb perfusion for malignant melanoma and soft tissue sarcoma. Eur J Surg Oncol 1990; 16: 370–5.
  • Hoekstra Hi, Schraffordt KH, de Vries LG, van Weerden TW, Oldhoff J. Toxicity of hyperthermic isolated limb perfusion with cisplatin for recurrent melanoma of the lower extremity after previous perfusion treatment. Cancer 1993; 72: 1224–9.
  • Van Ginkel RJ, Schraffordt KH, de Vries EG, Molenaar WM, Uges DR, Hoekstra Hyperthermic isolated limb perfusion with cisplatin in four patients with sarcomas of soft tissue and bone. Eur J Surg Oncol 1996; 22: 528–31.
  • Schraffordt Koops H, Eggermont AM, Lienard D, Kroon BB, Hoekstra Hi, van Geel AN, Nieweg OE, Lejeune FJ. Hyperthermic isolated limb perfusion for the treatment of soft tissue sarcomas. Semin Surg Oncol 1998; 14: 210–14.
  • Drory VE, Lev D, Groozman GB, Gutmann M, Klausner JM. Neurotoxicity of isolated limb perfusion with tumor necrosis factor. J Neurol Sci 1998; 158: 1–4.
  • Daryanani D, de Vries EG, Guchelaar Hi, van Weerden TW, Hoekstra Hi. Hyperthermic isolated regional perfusion of the limb with carboplatin. Eur J Surg Oncol 2000; 26: 792–7.
  • Bonifati DM, On C, Rossi CR, Caira S, Fanin M, Angelini C. Neuromuscular damage after hyperthermic isolated limb perfusion in patients with melanoma or sarcoma treated with chemotherapeutic agents. Cancer Chemother Pharmacol 2000; 46: 517–22.
  • Wiedemann GJ, Robins HI, Gutsche S, Mentzel M, Deeken M, Katschinski DM, Eleftheriadis S, Crahe R, Weiss C, Storer B, Wagner T. Ifosfamide, carboplatin and etoposide (ICE) combined with 41.8 degrees C whole body hyperthermia in patients with refractory sarcoma. Eur J Cancer 1996; 32A: 888–92.
  • Wiedemann GJ, d'Oleire F, Knop E, Eleftheriadis S, Bucsky P, Feddersen S, Klouche M, Geisler J, Mentzel M, Schmucker P. Ifosfamide and carboplatin combined with 41.8 degrees C whole-body hyperthermia in patients with refractory sarcoma and malignant teratoma. Cancer Res 1994; 54: 5346–50.

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