Gadolinium-doped iron oxide nanoparticles induced magnetic field hyperthermia combined with radiotherapy increases tumour response by vascular disruption and improved oxygenation

References

• Hiergeist R, Andra W, Buske N, et al. (1999). Application of magnetite ferrofluids for hyperthermia. J Magn Magn Mater 201:420–2.
   Web of Science ®Google Scholar
• Pankhurst QA, Connolly J, Jones SK, Dobson J. (2003). Applications of magnetic nanoparticles in biomedicine. J Phys D Appl Phys 36:R167–81.
   Web of Science ®Google Scholar
• Duguet E, Vasseur S, Mornet S, Devoisselle J-M. (2006). Magnetic nanoparticles and their applications in medicine. Nanomedicine 1:157–68.
   PubMed Web of Science ®Google Scholar
• Yallapu MM, Othman SF, Curtis ET, et al. (2011). Multi-functional magnetic nanoparticles for magnetic resonance imaging and cancer therapy. Biomaterials 32:1890–905.
   PubMed Web of Science ®Google Scholar
• Jordan A, Scholz R, Wust P, et al. (1999). Magnetic fluid hyperthermia (MFH): cancer treatment with AC magnetic field induced excitation of biocompatible superparamagnetic nanoparticles. J Magn Magn Mater 201:413–19.
   Web of Science ®Google Scholar
• Moroz P, Jones SK, Gray BN. (2002). Magnetically mediated hyperthermia: current status and future directions. Int J Hypertherm 18:267–84.
   PubMed Web of Science ®Google Scholar
• Salunkhe AB, Khot VM, Pawar SH. (2014). Magnetic hyperthermia with magnetic nanoparticles: a status review. Curr Top Med Chem 14:572–94.
   PubMed Web of Science ®Google Scholar
• Rosensweig RE. (2002). Heating magnetic fluid with alternating magnetic field. J Magn Magn Mater 252:370–4.
   Web of Science ®Google Scholar
• Babincova M, Altanerova V, Altaner C, et al. (2004). In vivo heating of magnetic nanoparticles in alternating magnetic field. Med Phys 31:2219–21.
   PubMed Web of Science ®Google Scholar
• Wang XM, Gu HC, Yang ZQ. (2005). The heating effect of magnetic fluids in an alternating magnetic field. J Magn Magn Mater 293:334–40.
   Web of Science ®Google Scholar
• Ma M, Wu Y, Zhou H, et al. (2004). Size dependence of specific power absorption of Fe3O4 particles in AC magnetic field. J Magn Magn Mater 268:33–9.
   Web of Science ®Google Scholar
• Drake P, Cho H-J, Shih P-S, et al. (2007). Gd-doped iron-oxide nanoparticles for tumour therapy via magnetic field hyperthermia. J Mater Chem 17:4914–18.
   Web of Science ®Google Scholar
• Jiang P-S, Drake P, Cho H-J, et al. (2012). Tailored nanoparticles for tumour therapy. J Nanosci Nanotechnol 12:5076–81.
   PubMed Web of Science ®Google Scholar
• Horsman MR, Overgaard J. (2007). Hyperthermia: a potent enhancer of radiotherapy. Clin Oncol (R Coll Radiol) 19:418–26.
   PubMed Web of Science ®Google Scholar
• Moeller BJ, Richardson RA, Dewhirst MW. (2007). Hypoxia and radiotherapy: opportunities for improved outcomes in cancer treatment. Cancer Metastasis Rev 26:241–8.
   PubMed Web of Science ®Google Scholar
• Tarnawski R, Kummermehr J, Trott KR. (1998). The radiosensitivity of recurrent clones of an irradiated murine squamous cell carcinoma in the in vitro megacolony system. Radiother Oncol 46:209–14.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Li M, Yao Q, Chen C. (2007). Recent advances in tumor hypoxia: tumor progression, molecular mechanisms, and therapeutic implications. Med Sci Monitor 13:RA175–80.
   PubMed Web of Science ®Google Scholar
• Iversen AB, Busk M, Horsman MR. (2013). Induction of hypoxia by vascular disrupting agents and the significance for their combination with radiation therapy. Acta Oncol 52:1320–6.
   PubMed Web of Science ®Google Scholar
• Kampinga HH, Dikomey E. (2001). Hyperthermic radiosensitization: mode of action and clinical relevance. Int J Radiat Biol 77:399–408.
   PubMed Web of Science ®Google Scholar
• Wust P, Hildebrandt B, Sreenivasa G, et al. (2002). Hyperthermia in combined treatment of cancer. Lancet Oncol 3:487–97.
   PubMed Web of Science ®Google Scholar
• Diagaradjane P, Shetty A, Wang JC, et al. (2008). Modulation of in vivo tumor radiation response via gold nanoshell-mediated vascular-focused hyperthermia: characterizing an integrated antihypoxic and localized vascular disrupting targeting strategy. Nano Lett 8:1492–500.
   PubMed Web of Science ®Google Scholar
• Griffin RJ, Dings RPM, Jamshidi-Parsian A, Song CW. (2010). Mild temperature hyperthermia and radiation therapy: role of tumour vascular thermotolerance and relevant physiological factors. Int J Hyperthermia 26:256–63.
   PubMed Web of Science ®Google Scholar
• Johannsen M, Thiesen B, Gneveckow U, et al. (2006). Thermotherapy using magnetic nanoparticles combined with external radiation in an orthotopic rat model of prostate cancer. Prostate 66:97–104.
   PubMed Web of Science ®Google Scholar
• Attaluri A, Kandala SK, Wabler M, et al. (2015). Magnetic nanoparticle hyperthermia enhances radiation therapy: a study in mouse models of human prostate cancer. Int J Hyperthermia 31:359–74.
   PubMed Web of Science ®Google Scholar
• Foster BAGJ, Kwon ED, Madias C, Greenberg NM. (1997). Characterization of prostatic epithelial cell lines derived from transgenic adenocarcinoma of the mouse prostate (TRAMP) model. Cancer Res 57:5.
   Web of Science ®Google Scholar
• Chen F-H, Chiang C-S, Wang C-C, et al. (2009). Radiotherapy decreases vascular density and causes hypoxia with macrophage aggregation in TRAMP-C1 prostate tumors. Clin Cancer Res 15:1721–9.
   PubMed Web of Science ®Google Scholar
• Wang Q, Deng ZS, Liu J. (2012). Theoretical evaluations of magnetic nanoparticle-enhanced heating on tumor embedded with large blood vessels during hyperthermia. J Nanopart Res 14:974–983.
   Web of Science ®Google Scholar
• Hsieh Y-K, Jiang P-S, Yang B-S, et al. (2011). Using laser ablation/inductively coupled plasma mass spectrometry to bioimage multiple elements in mouse tumors after hyperthermia. Anal Bioanal Chem 401:909–15.
   PubMed Web of Science ®Google Scholar
• Diederich CJ. (2005). Thermal ablation and high-temperature thermal therapy: overview of technology and clinical implementation. Int J Hyperthermia 21:745–53.
   PubMed Web of Science ®Google Scholar
• Song CW. (1984). Effect of local hyperthermia on blood flow and microenvironment: a review. Cancer Res 44:10.
   Web of Science ®Google Scholar
• Song CW, Shakil A, Osborn JL, Iwata K. (2009). Tumour oxygenation is increased by hyperthermia at mild temperatures. Int J Hyperthermia 25:91–5.
   PubMed Web of Science ®Google Scholar
• Hokland SL, Nielsen T, Busk M, Horsman MR. (2010). Imaging tumour physiology and vasculature to predict and assess response to heat. Int J Hyperthermia 26:264–72.
   PubMed Web of Science ®Google Scholar
• Song CW, Park HJ, Lee CK, Griffin R. (2005). Implications of increased tumor blood flow and oxygenation caused by mild temperature hyperthermia in tumor treatment. Int J Hyperthermia 21:761–7.
   PubMed Web of Science ®Google Scholar
• Jain RK. (2005). Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 307:58–62.
   PubMed Web of Science ®Google Scholar
• Johannsen M, Jordan A, Scholz R, et al. (2004). Evaluation of magnetic fluid hyperthermia in a standard rat model of prostate cancer. J Endourol 18:495–500.
   PubMed Web of Science ®Google Scholar
• Johannsen M, Gneveckow U, Eckelt L, et al. (2005). Clinical hyperthermia of prostate cancer using magnetic nanoparticles: presentation of a new interstitial technique. Int J Hypertherm 21:637–47.
   PubMed Web of Science ®Google Scholar
• Johannsen M, Gneueckow U, Thiesen B, et al. (2007). Thermotherapy of prostate cancer using magnetic nanoparticles: Feasibility, imaging, and three-dimensional temperature distribution. Eur Urol 52:1653–62.
   PubMed Web of Science ®Google Scholar