Head-out immersion in hot water increases serum BDNF in healthy males

References

• Soppet D, Escandon E, Maragos J, et al. (1991). The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor. Cell 65:895–903.
   PubMed Web of Science ®Google Scholar
• Thoesen H. (1995). Neurotrophins and neuronal plasticity. Science 270:593–8.
   PubMed Web of Science ®Google Scholar
• Bibel M, Barde YA. (2000). Neurotrophins: key regulators of cell fate and shape in the vertebrate nervous system. Genes Dev 14:2917–37.
   Web of Science ®Google Scholar
• Poo MM. (2001). Neurotrophins as synaptic modulators. Nat Rev Neurosci 2:24–32.
   PubMed Web of Science ®Google Scholar
• Carter AR, Chen C, Schwartz M, et al. (2002). Brain-derived neurotrophic factor modulates cerebellar plasticity and synaptic ultrastructure. J Neurosci 22:1316–27.
   PubMed Web of Science ®Google Scholar
• Nakagawa T, Tsuchida A, Itakura Y, et al. (2000). Brain-derived neurotrophic factor regulates glucose metabolism by modulating energy balance in diabetic mice. Diabetes 49:436–44.
   PubMed Web of Science ®Google Scholar
• Duman RS. (2002). Synaptic plasticity and mood disorders. Mol Psychiatry 7:S29–S34.
   PubMed Web of Science ®Google Scholar
• Unger TJ, Calderon GA, Bradley LC, et al. (2007). Selective deletion of Bdnf in the ventromedial and dorsomedial hypothalamus of adult mice results in hyperphagic behavior and obesity. J Neurosci 27:14265–74.
   PubMed Web of Science ®Google Scholar
• Karege F, Schwald M, Cisse M. (2002). Postnatal developmental profiles of brain-derived neurotrophic factor in rat brain and platelets. Neurosci Lett 328:261–4.
   PubMed Web of Science ®Google Scholar
• Laske C, Stransky E, Leyhe T, et al. (2005). Stage-dependent BDNF serum concentrations in Alzheimer's disease. J Neural Transm (Vienna) 113:1217–24.
   PubMed Web of Science ®Google Scholar
• Neeper SA, Gomes-Pinilla F, Choi J, et al. (1996). Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain. Brain Res 726:49–56.
   PubMed Web of Science ®Google Scholar
• Ethan RN. (1985). Physiological adaptations to aerobic training: the increase in blood volume induced by aerobic conditioning is a critical factor in improving performance and promoting resistance to fatigue. Am Sci 73:334–43.
   Google Scholar
• Goekint M, Roelands B, Heyman E, et al. (2011). Influence of citalopram and environmental temperature on exercise-induced changes in BDNF. Neurosci Lett 494:150–4.
   PubMed Web of Science ®Google Scholar
• Fippel A, Von Sandersleben A, Bangert K, et al. (2007). Monitoring of whole-body hyperthermia with transesophageal echocardiography (TEE). Int J Hyperthermia 23:457–66.
   PubMed Web of Science ®Google Scholar
• Dewhirst MW, Lee CT, Ashcraft KA. (2016). The future of biology in driving the field of hyperthermia. Int J Hyperthermia 32:4–13.
   PubMed Web of Science ®Google Scholar
• Fisher DT, Chen Q, Skitzki JJ, et al. (2011). IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells. J Clin Investig 121:3846–59.
   PubMed Web of Science ®Google Scholar
• van den Tempel N, Horsman MR, Kanaar R. (2016). Improving efficacy of Hyperthermia in oncology by exploiting biological mechanisms. Int J Hyperthermia 32:446–54.
   PubMed Web of Science ®Google Scholar
• Maisonpierre PC, Belluscio L, Squinto S, et al. (1990). Neurotrophin-3: a neurotrophic factor related to NGF and BDNF. Science 247:1446–51.
   PubMed Web of Science ®Google Scholar
• Maisonpierre PC, Le Beau ME, Espinosa R, 3rd, et al. (1991). Human and rat brain- derived neurotrophic growth factor and neurotrophin-3: gene structure, distributions, and chromosomal localizations. Genomics 10:558–68.
   PubMed Web of Science ®Google Scholar
• Kerschensteiner M, Gallmeier E, Behrens L, et al. (1999). Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions; a neuroprotective role of inflammation? J Exp Med 189:865–70.
   PubMed Web of Science ®Google Scholar
• Poduslo JF, Curran GL. (1996). Permeability at the blood–brain and blood–nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF. Brain Res Mol Brain Res 36:280–6.
   PubMedGoogle Scholar
• Pan W, Banks WA, Fasold MB, et al. (1998). Transport of brain-derived neurotrophic factor across the blood-brain barrier. Neuropharmacology 37:1553–61.
   PubMed Web of Science ®Google Scholar
• Watson P, Shirreffs SM, Maughan RJ. (2005). Blood–brain barrier integrity may be threatened by exercise in a warm environment. Am J Physiol Regul Integr Comp Physiol 288:R1689–94.
   PubMed Web of Science ®Google Scholar
• Kapural M, Krizanac-Bengez L, Barnettt G, et al. (2002). Serum S-100beta as a possible marker of blood-brain barrier disruption. Brain Res 940:102–4.
   PubMed Web of Science ®Google Scholar
• Gould E, Cameron HA, Danieles DC, et al. (1992). Adrenal hormones suppress cell division in the adult rat dentate gyrus. J Neurosci 15:3642–50.
   Google Scholar
• Smith MA, Makino S, Kvetnansky R, et al. (1995). Stress and glucocorticoids affects the expression of brain-derived neurotrophic factor and neurotrophin-3 in the hippocampus. J Neurosci 15:1768–77.
   PubMed Web of Science ®Google Scholar
• McMorris T, Harris RC, Swain J, et al. (2006). Effect of creatine supplementation and sleep deprivation, with mild exercise, on cognitive and psychomotor performance, mood state, and plasma concentrations of catecholamines and cortisol. Psychopharmacology 185:93–103.
   PubMed Web of Science ®Google Scholar
• Rasmussen P, Brassard P, Adser H, et al. (2009). Evidence for a release of brain-derived neurotrophic factor from the brain during exercise. Exp Physiol 94:1062–9.
   PubMed Web of Science ®Google Scholar
• Nofuji Y, Suwa M, Ichimiya A, et al. (2012). Different circulating brain-derived neurotrophic factor responses to acute exercise between physically active and sedentary subjects. J Sports Sci Med 11:83–8.
   PubMed Web of Science ®Google Scholar
• Herrmann M, Jost S, Kutz S, et al. (2000). Temporal profile of release of neurobiochemical markers of brain damage after traumatic brain injury is associated with intracranial pathology as demonstrated in cranial computerized tomography. J Neurotrauma 17:113–22.
   PubMed Web of Science ®Google Scholar
• Zimmer DB, Cornwall EH, Landar A, et al. (2005). The S100 protein family: history, function, and expression. Brain Res Bull 37:417–29.
   Web of Science ®Google Scholar
• Hasselblatt M, Mooren FC, von Ahsen N, et al. (2004). Serum S100beta increases in marathon runners reflect extracranial release rather than glial damage. Neurology 62:1634–6.
   PubMed Web of Science ®Google Scholar
• Laatikainen T, Salminen K, Kohvakka A, et al. (1988). Response of plasma endorphins, prolactin and catecholamines in women to intense heat in a sauna. Eur J Appl Physiol Occup Physiol 57:98–102.
   PubMed Web of Science ®Google Scholar
• Schaaf MJ, de Jong J, de Kloet ER, et al. (1998). Downregulation of BDNF mRNA and protein in the rat hippocampus by corticosterone. Brain Res 813:112–20.
   PubMed Web of Science ®Google Scholar
• Fujimura H, Altar CA, Chen R, et al. (2002). Brain-derived neurotrophic factor is stored in human platelets and released by agonist stimulation. Thromb Haemost 87:728–34.
   PubMed Web of Science ®Google Scholar
• Brenner IK, Zamecnik J, Shek PN, et al. (1997). The impact of heat exposure and repeated exercise on circulating stress hormones. Eur J Appl Physiol Occup Physiol 76:445–54.
   PubMed Web of Science ®Google Scholar