Temperature and thermal dose during radiotherapy and hyperthermia for recurrent breast cancer are related to clinical outcome and thermal toxicity: a systematic review

References

• Franckena M, van der Zee J. Use of combined radiation and hyperthermia for gynecological cancer. Curr Opin Obstet Gynecol. 2010;22(1):9–14.
   PubMed Web of Science ®Google Scholar
• Overgaard J, Gonzalez Gonzalez D, Hulshof MC, et al. Hyperthermia as an adjuvant to radiation therapy of recurrent or metastatic malignant melanoma. A multicentre randomized trial by the European Society for Hyperthermic Oncology. Int J Hyperth. 1996;12(1):3–20.
   PubMed Web of Science ®Google Scholar
• van der Zee J, González González D, van Rhoon GC, et al. Comparison of radiotherapy alone with radiotherapy plus hyperthermia in locally advanced pelvic tumours: a prospective, randomised, multicentre trial. Dutch Deep Hyperthermia Group. Lancet. 2000;355(9210):1119–1125.
   PubMed Web of Science ®Google Scholar
• Vernon CC, Hand JW, Field SB, et al. Radiotherapy with or without hyperthermia in the treatment of superficial localized breast cancer: Results from five randomized controlled trials. International Collaborative Hyperthermia Group. Int J Radiat Oncol Biol Phys. 1996;35:731–744.
   PubMed Web of Science ®Google Scholar
• Issels RD, Lindner LH, Verweij J, et al. Neo-adjuvant chemotherapy alone or with regional hyperthermia for localised high-risk soft-tissue sarcoma: a randomised phase 3 multicentre study. Lancet Oncol. 2010;11(6):561–570.
   PubMed Web of Science ®Google Scholar
• Datta NR, Puric E, Klingbiel D, et al. Hyperthermia and radiation therapy in locoregional recurrent breast cancers: a systematic review and meta-analysis. Int J Radiat Oncol Biol Phys. 2016;94(5):1073–1087.
   PubMed Web of Science ®Google Scholar
• Perez CAA, Pajak T, Emami B, et al. Randomized phase III study comparing irradiation and hyperthermia with irradiation alone in superficial measurable tumors. Final report by the Radiation Therapy Oncology Group. Am J Clin Oncol. 1991;14(2):133–141.
   PubMed Web of Science ®Google Scholar
• Engin K, Tupchong L, Waterman FM, et al. Multiple field hyperthermia combined with radiotherapy in advanced carcinoma of the breast. Int J Hyperth. 1994;10(5):587–603.
   PubMed Web of Science ®Google Scholar
• Stauffer PR. Evolving technology for thermal therapy of cancer. Int J Hyperth. 2005;21(8):731–744.
   PubMed Web of Science ®Google Scholar
• Crezee H, Van Leeuwen CM, Oei AL, et al. Thermoradiotherapy planning: integration in routine clinical practice. Int J Hyperth. 2016;32(1):41–49.
   PubMed Web of Science ®Google Scholar
• Overgaard J. Simultaneous and sequential hyperthermia and radiation treatment of an experimental tumor and its surrounding normal tissue in vivo. Int J Radiat Oncol Biol Phys. 1980;6(11):1507–1517.
   PubMed Web of Science ®Google Scholar
• Westra A, Dewey WC. Variation in sensitivity to heat shock during the cell-cycle of Chinese hamster cells in vitro. Int J Radiat Oncol Biol Phys. 1971;19:467–477.
   Google Scholar
• George KC, Streffer C, Pelzer T. Combined effects of X rays, Ro 03-8799, and hyperthermia on growth, necrosis, and cell proliferation in a mouse tumor. Int J Radiat Oncol Biol Phys. 1989;16(4):1119–1122.
   PubMed Web of Science ®Google Scholar
• Field SB, Morris CC. The relationship between heating time and temperature: its relevance to clinical hyperthermia. Radiother Oncol. 1983;1(2):179–186.
   PubMedGoogle Scholar
• Sherar M, Liu FF, Pintilie M, et al. Relationship between thermal dose and outcome in thermoradiotherapy treatments for superficial recurrences of breast cancer: data from a phase III trial. Int J Radiat Oncol Biol Phys. 1997;39(2):371–380.
   PubMed Web of Science ®Google Scholar
• Jones EL, Oleson JR, Prosnitz LR, et al. Randomized trial of hyperthermia and radiation for superficial tumors. J Clin Oncol. 2005;23(13):3079–3085.
   PubMed Web of Science ®Google Scholar
• Van Rhoon GC. Is CEM43 still a relevant thermal dose parameter for hyperthermia treatment monitoring? Int J Hyperth. 2016;32(1):50–62.
   PubMed Web of Science ®Google Scholar
• Nielsen OS, Overgaard J. Importance of preheating temperature and time for the induction of thermotolerance in a solid tumour in vivo. Br J Cancer. 1982;46(6):894–903.
   PubMed Web of Science ®Google Scholar
• Dewhirst MW, Viglianti BL, Lora-Michiels M, et al. Basic principles of thermal dosimetry and thermal thresholds for tissue damage from hyperthermia. Int J Hyperth. 2003;19(3):267–294.
   PubMed Web of Science ®Google Scholar
• Sapareto SA, Dewey WC. Thermal dose determination in cancer therapy. Int J Radiat Oncol Biol Phys. 1984;10(6):787–800.
   PubMed Web of Science ®Google Scholar
• Kroesen M, Mulder HT, van Holthe JML, et al. Confirmation of thermal dose as a predictor of local control in cervical carcinoma patients treated with state-of-the-art radiation therapy and hyperthermia. Radiother Oncol. 2019;140:150–158.
   PubMed Web of Science ®Google Scholar
• Franckena M, Fatehi D, de Bruijne M, et al. Hyperthermia dose-effect relationship in 420 patients with cervical cancer treated with combined radiotherapy and hyperthermia. Eur J Cancer. 2009;45(11):1969–1978.
   PubMed Web of Science ®Google Scholar
• Leopold KA, Dewhirst M, Samulski T, et al. Relationships among tumor temperature, treatment time, and histopathological outcome using preoperative hyperthermia with radiation in soft tissue sarcomas. Int J Radiat Oncol Biol Phys. 1992;22(5):989–998.
   PubMed Web of Science ®Google Scholar
• Moher D, Liberati A, Tetzlaff J, et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):e1000097.
   PubMed Web of Science ®Google Scholar
• Agresti A, Categorical data analysis. In: Balding DJ, Bloomfield P, Cressie NAC, et al., editors. Categorical data analysis. 2nd ed. Hoboken, (NJ): Wiley Interscience; 2002. p. 54.
   Google Scholar
• Hayden JA, Van Der Windt DA, Cartwright JL, et al. Assessing bias in studies of prognostic factors. Ann Intern Med. 2013;158(4):280–286.
   PubMed Web of Science ®Google Scholar
• Hand JW, Machin D, Vernon CC, et al. Analysis of thermal parameters obtained during phase III trials of hyperthermia as an adjunct to radiotherapy in the treatment of breast carcinoma. Int J Hyperth. 1997;13(4):343–364.
   PubMed Web of Science ®Google Scholar
• Dragovic J, Seydel HG, Sandhu T, et al. Local superficial hyperthermia in combination with low-dose radiation therapy for palliation of locally recurrent breast carcinoma. J Clin Oncol. 1989;7(1):30–35.
   PubMed Web of Science ®Google Scholar
• Gonzalez Gonzalez D, van Dijk JD, Blank LE. Chestwall recurrences of breast cancer: results of combined treatment with radiation and hyperthermia. Radiother Oncol. 1988;12(2):95–103.
   PubMed Web of Science ®Google Scholar
• Phromratanapongse P, Steeves RA, Severson SB, et al. Hyperthermia and irradiation for locally recurrent previously irradiated breast cancer. Strahlentherapie Und Onkol. 1991;167:93–97.
   PubMedGoogle Scholar
• Refaat T, Sachdev S, Sathiaseelan V, et al. Hyperthermia and radiation therapy for locally advanced or recurrent breast cancer. Breast. 2015;24(4):418–425.
   PubMed Web of Science ®Google Scholar
• Gabriele P, Ferrara T, Baiotto B, et al. Radio hyperthermia for re-treatment of superficial tumours. Int J Hyperth. 2009;25(3):189–198.
   PubMed Web of Science ®Google Scholar
• Seegenschmiedt HM, Karlsson UL, Sauer R, et al. Superficial chest wall recurrences of breast cancer: prognostic treatment factors for combined radiation therapy and hyperthermia. Radiology. 1989;173(2):551–558.
   PubMed Web of Science ®Google Scholar
• Sannazzari GL, Gabriele P, Orecchia R, et al. Results of hyperthermia, alone or combined with irradiation, in chest wall recurrences of breast cancer. Tumori 1989;75(3):284–288.
   PubMed Web of Science ®Google Scholar
• Kapp DS, Barnett TA, Cox RS, et al. Hyperthermia and radiation therapy of local-regional recurrent breast cancer: prognostic factors for response and local control of diffuse or nodular tumors. Int J Radiat Oncol Biol Phys. 1991;20(5):1147–1164.
   PubMed Web of Science ®Google Scholar
• Kapp DS, Cox RS, Barnett TA, et al. Thermoradiotherapy for residual microscopic cancer: elective or post-excisional hyperthermia and radiation therapy in the management of local–regional recurrent breast cancer. Int J Radiat Oncol Biol Phys. 1992;24(2):261–277.
   PubMed Web of Science ®Google Scholar
• Lee HK, Antell AG, Perez CA, et al. Superficial hyperthermia and irradiation for recurrent breast carcinoma of the chest wall: prognostic factors in 196 tumors. Int J Radiat Oncol Biol Phys. 1998;40(2):365–375.
   PubMed Web of Science ®Google Scholar
• Arcangeli G, Casale C, Colistro F, et al. One versus four heat treatments in combination with radiotherapy in metastatic mammary carcinoma. Int J Radiat Oncol Biol Phys. 1991;21(6):1569–1574.
   PubMed Web of Science ®Google Scholar
• Lindholm C-E, Kjellen E, Nilsson P, et al. Prognostic factors for tumour response and skin damage to combined radiotherapy and hyperthermia in superficial recurrent breast carcinomas. Int J Hyperth. 1995;11(3):337–355.
   PubMed Web of Science ®Google Scholar
• Linthorst M, Baaijens M, Wiggenraad R, et al. Local control rate after the combination of re-irradiation and hyperthermia for irresectable recurrent breast cancer: results in 248 patients. Radiother Oncol. 2015;117(2):217–222.
   PubMed Web of Science ®Google Scholar
• Linthorst M, van Geel AN, Baaijens M, et al. Re-irradiation and hyperthermia after surgery for recurrent breast cancer. Radiother Oncol. 2013;109(2):188–193.
   PubMed Web of Science ®Google Scholar
• Van Der Zee J, Van Der Holt B, Rietveld PJM, et al. Reirradiation combined with hyperthermia in recurrent breast cancer results in a worthwhile local palliation. Br J Cancer. 1999;79:483–490.
   PubMed Web of Science ®Google Scholar
• Li G, Mitsumori M, Ogura M, et al. Local hyperthermia combined with external irradiation for regional recurrent breast carcinoma. Int J Clin Oncol. 2004;9(3):179–183.
   PubMedGoogle Scholar
• Oldenborg S, Griesdoorn V, Van Os R, et al. Reirradiation and hyperthermia for irresectable locoregional recurrent breast cancer in previously irradiated area: size matters. Radiother Oncol. 2015;117(2):223–228.
   PubMed Web of Science ®Google Scholar
• Ben-Yosef R, Kapp DS, B-Y R. Persistent and/or late complications of combined radiation therapy and hyperthermia. Int J Hyperth. 1992;8(6):733–745.
   PubMed Web of Science ®Google Scholar
• Hehr T, Lamprecht U, Glocker S, et al. Thermoradiotherapy for locally recurrent breast cancer with skin involvement. Int J Hyperth. 2001;17(4):291–301.
   PubMed Web of Science ®Google Scholar
• Lee ER, Kapp DS, Lohrbach AW, et al. Influence of water bolus temperature on measured skin surface and intradermal temperatures. Int J Hyperth. 1994;10(1):59–72.
   PubMed Web of Science ®Google Scholar
• Bakker A, Kolff MW, Holman R, et al. Thermal skin damage during reirradiation and hyperthermia is time-temperature dependent. Int J Radiat Oncol Biol Phys. 2017;98(2):392–399.
   PubMed Web of Science ®Google Scholar
• Engin K, Tupchong L, Waterman FM, et al. Patchwork fields in thermoradiotherapy for extensive chest wall recurrences of breast carcinoma. Breast Cancer Res Tr. 1993;27(3):263–270.
   PubMed Web of Science ®Google Scholar
• Lindholm C, Kjellen E, Nilsson P, et al. Microwave-induced hyperthermia and radiotherapy in human superficial tumours: clinical results with a comparative study of combined treatment versus radiotherapy alone. Int J Hyperth. 1987;3(5):393–411.
   PubMed Web of Science ®Google Scholar
• Dobšíček Trefná H, Crezee H, Schmidt M, et al. Quality assurance guidelines for superficial hyperthermia clinical trials: I. Clinical requirements. Int J Hyperth. 2017;33(4):471–482.
   PubMed Web of Science ®Google Scholar
• Schooneveldt G, Bakker A, Balidemaj E, et al. Thermal dosimetry for bladder hyperthermia treatment. An overview. Int J Hyperth. 2016;32(4):417–433.
   PubMed Web of Science ®Google Scholar
• Bakker A, Holman R, Rodrigues D, et al. Analysis of the required number of sensors for adequate monitoring of skin temperature distribution during superficial microwave hyperthermia treatment. Strahlentherapie Und Onkol. 2018;194:485–486.
   Web of Science ®Google Scholar
• Cox RS, Kapp DS. Correlation of thermal parameters with outcome in combined radiation therapy-hyperthermia trials. Int J Hyperth. 1992;8(6):719–732.
   PubMed Web of Science ®Google Scholar
• Edelstein-Keshet L, Dewhirst MW, Oleson JR, et al. Characterization of tumour temperature distributions in hyperthermia based on assumed mathematical forms. Int J Hyperth. 1989;5(6):757–777.
   PubMed Web of Science ®Google Scholar
• Oleson JR, Samulski TV, Leopold KA, et al. Sensitivity of hyperthermia trial outcomes to temperature and time: implications for thermal goals of treatment. Int J Radiat Oncol Biol Phys. 1993;25(2):289–297.
   PubMed Web of Science ®Google Scholar
• Corry PM, Jabboury K, Kong JS, et al. Evaluation of equipment for hyperthermic treatment of cancer. Int J Hyperth. 1988;4(1):53–74.
   PubMed Web of Science ®Google Scholar
• Perez CA, Gillespie B, Pajak T, et al. Quality assurance problems in clinical hyperthermia and their impact on therapeutic outcome: a report by the Radiation Therapy Oncology Group. Int J Radiat Oncol Biol Phys. 1989;16(3):551–558.
   PubMed Web of Science ®Google Scholar
• Oldenborg S, Van Os RM, Van Rij CM, et al. Elective re-irradiation and hyperthermia following resection of persistent locoregional recurrent breast cancer: a retrospective study. Int J Hyperth. 2010;26(2):136–144.
   PubMed Web of Science ®Google Scholar
• Keilholz L, Seegenschmiedt MH, Martus P, et al. Prospective randomized study to compare once versus twice weekly hyperthermia applications and conventional radiotherapy for chestwall recurrences of breast cancer: 10 year results. Proceedings of the 39th Annual ASTRO Meeting; 1997 Oct 19–23; Orlando (FL); 1997. p. 265.
   Google Scholar
• Kapp DS, Petersen IA, Cox RS, et al. Two or six hyperthermia treatments as an adjunct to radiation therapy yield similar tumor responses: results of a randomized trial. Int J Radiat Oncol Biol Phys. 1990;19(6):1481–1495.
   PubMed Web of Science ®Google Scholar
• Greenhalgh DG, Lawless MB, Chew BB, et al. Temperature threshold for burn injury: an oximeter safety study. J Burn Care Rehabil. 2004;25(5):411–415.
   PubMedGoogle Scholar
• Yarmolenko PS, Moon EJ, Landon C, et al. Thresholds for thermal damage to normal tissues: an update. Int J Hyperth. 2011;27(4):320–343.
   PubMed Web of Science ®Google Scholar
• Ohguri T, Harima Y, Imada H, et al. Relationships between thermal dose parameters and the efficacy of definitive chemoradiotherapy plus regional hyperthermia in the treatment of locally advanced cervical cancer: data from a multicentre randomised clinical trial. Int J Hyperth. 2018;34(4):461–468.
   PubMed Web of Science ®Google Scholar
• Issels RD, Mittermüller J, Gerl A, et al. Improvement of local control by regional hyperthermia combined with systemic chemotherapy (ifosfamide plus etoposide) in advanced sarcomas: updated report on 65 patients. J Cancer Res Clin Oncol. 1991;117(S4):S141–S7.
   PubMed Web of Science ®Google Scholar
• Wust P, Rau B, Gellerman J, et al. Radiochemotherapy and hyperthermia in the treatment of rectal cancer. Recent Results Cancer Res. 1998;146:175–191.
   PubMedGoogle Scholar
• Sneed P, Stauffer P, Gutin P, et al. Interstitial irradiation and hyperthermia for the treatment of recurrent malignant brain tumors. Neurosurgery. 1991;28(2):206–215.
   PubMed Web of Science ®Google Scholar
• Emami B, Perez CA, Konefal J, et al. Thermoradiotherapy of malignant melanoma. Int J Hyperth. 1988;4(4):373–381.
   PubMed Web of Science ®Google Scholar
• Seegenschmiedt MH, Martus P, Fietkau R, et al. Multivariate analysis of prognostic parameters using interstitial thermoradiotherapy (IHT-IRT): tumor and treatment variables predict outcome. Int J Radiat Oncol Biol Phys. 1994;29(5):1049–1063.
   PubMed Web of Science ®Google Scholar
• Dewhirst MW, Sim DA. The utility of thermal dose as a predictor of tumor and normal tissue responses to combined radiation and hyperthermia. Cancer Res. 1984;44:4772–4780.
   PubMed Web of Science ®Google Scholar
• Dewhirst MW, Connor WG, Sim DA, et al. Importance of minimum tumor temperature in determining early and long-term responses of spontaneous canine and feline tumors to heat and radiation. Cancer Res. 1984;44(1):43–50.
   PubMed Web of Science ®Google Scholar
• Dewhirst MW, Sim DA. Estimation of therapeutic gain in clinical trials involving hyperthermia and radiotherapy? Int J Hyperth. 1986;2(2):165–178.
   PubMedGoogle Scholar
• Denman DL, Legorreta RA, Kier AB, et al. Therapeutic responses of spontaneous canine malignancies to combinations of radiotherapy and hyperthermia. Int J Radiat Oncol Biol Phys. 1991;21(2):415–422.
   PubMed Web of Science ®Google Scholar
• Oei AL, Vriend LEM, Crezee J, et al. Effects of hyperthermia on DNA repair pathways: one treatment to inhibit them all. Radiat Oncol. 2015;10(1):1–13.
   PubMed Web of Science ®Google Scholar
• Nielsen OS. Effect of fractionated hyperthermia on hypoxic cells in vitro. Int J Radiat Biol. 1981;39:73–82.
   Web of Science ®Google Scholar
• Dewhirst MW, Vujaskovic Z, Jones E, et al. Re-setting the biologic rationale for thermal therapy. Int J Hyperth. 2005;21(8):779–790.
   PubMed Web of Science ®Google Scholar
• Kok HP, Crezee J, Franken NAP, et al. Quantifying the combined effect of radiation therapy and hyperthermia in terms of equivalent dose distributions. Int J Radiat Oncol Biol Phys. 2014;88(3):739–745.
   PubMed Web of Science ®Google Scholar