An in vivo study of a custom-made high-frequency irreversible electroporation generator on different tissues for clinically relevant ablation zones

References

• Zhang B, Yang Y, Ding L, et al. Tumor ablation enhancement by combining radiofrequency ablation and irreversible electroporation: an in vitro 3D tumor study. Ann Biomed Eng. 2019;47(3):694–705.
   PubMed Web of Science ®Google Scholar
• Fang Z, Mao H, Moser MA, et al. Irreversible electroporation enhanced by radiofrequency ablation: an in vitro and computational study in a 3D liver tumor model. Ann Biomed Eng. 2021:1–13. DOI:https://doi.org/10.1007/s10439-021-02734-x
   PubMed Web of Science ®Google Scholar
• Sano MB, DeWitt MR, Teeter SD, et al. Optimization of a single insertion electrode array for the creation of clinically relevant ablations using high-frequency irreversible electroporation. Comput Biol Med. 2018;95:107–117.
   PubMed Web of Science ®Google Scholar
• Miklavčič D, Pucihar G, Pavlovec M, et al. The effect of high frequency electric pulses on muscle contractions and antitumor efficiency in vivo for a potential use in clinical electrochemotherapy. Bioelectrochemistry. 2005;65(2):121–128.
   PubMed Web of Science ®Google Scholar
• Arena CB, Sano MB, Rossmeisl JH, et al. High-frequency irreversible electroporation (H-FIRE) for non-thermal ablation without muscle contraction. Biomed Eng Online. 2011;10:102.
   PubMed Web of Science ®Google Scholar
• Sano MB, Arena CB, DeWitt MR, et al. In-vitro bipolar nano- and microsecond electro-pulse bursts for irreversible electroporation therapies. Bioelectrochemistry. 2014;100:69–79.
   PubMed Web of Science ®Google Scholar
• Novickij V, Ruzgys P, Grainys A, et al. High frequency electroporation efficiency is under control of membrane capacitive charging and voltage potential relaxation. Bioelectrochemistry. 2018;119:92–97.
   PubMed Web of Science ®Google Scholar
• Mercadal B, Beitel-White N, Aycock KN, et al. Dynamics of cell death after conventional IRE and H-FIRE treatments. Ann Biomed Eng. 2020;48(5):1451–1412.
   PubMed Web of Science ®Google Scholar
• Sano MB, Fan RE, Cheng K, et al. Reduction of muscle contractions during irreversible electroporation therapy using high-frequency bursts of alternating polarity pulses: a laboratory investigation in an Ex Vivo Swine Model. J Vasc Interv Radiol. 2018;29(6):893.e4–898.e4.
   Web of Science ®Google Scholar
• Bhonsle SP, Arena CB, Sweeney DC, et al. Mitigation of impedance changes due to electroporation therapy using bursts of high-frequency bipolar pulses. BioMed Eng Online. 2015;14(Suppl 3):S3.
   PubMed Web of Science ®Google Scholar
• Kaufman JD, Fesmire CC, Petrella RA, et al. High-frequency irreversible electroporation using 5,000-V waveforms to create reproducible 2- and 4-cm ablation zones-A laboratory investigation using mechanically perfused liver. J Vasc Interv Radiol. 2020;31(1):162.e7–168. e7.
   Web of Science ®Google Scholar
• Siddiqui IA, Latouche EL, DeWitt MR, et al. Induction of rapid, reproducible hepatic ablations using next-generation, high frequency irreversible electroporation (H-FIRE) in vivo. HPB. 2016;18(9):726–734.
   PubMed Web of Science ®Google Scholar
• Yao C, Dong S, Zhao Y, et al. Bipolar microsecond pulses and insulated needle electrodes for reducing muscle contractions during irreversible electroporation. IEEE Trans Biomed Eng. 2017;64(12):2924–2937.
   PubMed Web of Science ®Google Scholar
• Latouche EL, Arena CB, Ivey JW, et al. High-frequency irreversible electroporation for intracranial meningioma: a feasibility study in a spontaneous canine tumor model. Technol Cancer Res Treat. 2018;17:1533033818785285.
   Web of Science ®Google Scholar
• Ringel-Scaia VM, Beitel-White N, Lorenzo MF, et al. High-frequency irreversible electroporation is an effective tumor ablation strategy that induces immunologic cell death and promotes systemic anti-tumor immunity. EBioMedicine. 2019;44:112–125.
   PubMed Web of Science ®Google Scholar
• Ivey J, Wasson E, Alinezhadbalalami N, et al. Characterization of ablation thresholds for 3D-cultured patient-derived glioma stem cells in response to high-frequency irreversible electroporation. Research. 2019;2019:8081315.
   PubMedGoogle Scholar
• Dong S, Wang H, Zhao Y, et al. First human trial of high-frequency irreversible electroporation therapy for prostate cancer. Technol Cancer Res Treat. 2018;17:1533033818789692.
   Web of Science ®Google Scholar
• DeWitt MR, Lattouche E, Kaufman JD, et al. Simplified non-thermal tissue ablation with a single insertion device enabled by bipolar high-frequency pulses. IEEE Trans Biomed Eng. 2019;67(7):2043–2051.
   PubMed Web of Science ®Google Scholar
• Ivey JW, Latouche EL, Sano MB, et al. Targeted cellular ablation based on the morphology of malignant cells. Sci Rep. 2015;5:17157.
   PubMed Web of Science ®Google Scholar
• Sano MB, Volotskova O, Xing L. Treatment of cancer in vitro using radiation and high-frequency bursts of submicrosecond electrical pulses. IEEE Trans Biomed Eng. 2018;65(4):928–935.
   PubMed Web of Science ®Google Scholar
• Miklovic T, Latouche EL, DeWitt MR, et al. A comprehensive characterization of parameters affecting high-frequency irreversible electroporation lesions. Ann Biomed Eng. 2017;45(11):2524–2534.
   PubMed Web of Science ®Google Scholar
• O’Brien TJ, Passeri M, Lorenzo MF, et al. Experimental high-frequency irreversible electroporation using a single-needle delivery approach for nonthermal pancreatic ablation in vivo. J Vasc Interv Radiol. 2019;30(6):854.e7–862.e7.
   Web of Science ®Google Scholar
• Sano MB, Neal RE, Garcia PA, et al. Towards the creation of decellularized organ constructs using irreversible electroporation and active mechanical perfusion. Biomed Eng Online. 2010;9:83.
   PubMed Web of Science ®Google Scholar
• Edd JF, Horowitz L, Davalos RV, et al. In vivo results of a new focal tissue ablation technique: irreversible electroporation. IEEE Trans Biomed Eng. 2006;53(7):1409–1415.
   PubMed Web of Science ®Google Scholar
• Miklavčič D, Šemrov D, Mekid H, et al. A validated model of in vivo electric field distribution in tissues for electrochemotherapy and for DNA electrotransfer for gene therapy. Biochim Biophys Acta. 2000;1523(1):73–83.
   PubMed Web of Science ®Google Scholar
• Neal RE, Garcia PA, Kavnoudias H, et al. In vivo irreversible electroporation kidney ablation: experimentally correlated numerical models. IEEE Trans Biomed Eng. 2015;62(2):561–569.
   PubMed Web of Science ®Google Scholar
• Ben-David E, Ahmed M, Faroja M, et al. Irreversible electroporation: treatment effect is susceptible to local environment and tissue properties. Radiology. 2013;269(3):738–747.
   PubMed Web of Science ®Google Scholar
• Sweeney DC, Reberšek M, Dermol J, et al. Quantification of cell membrane permeability induced by monopolar and high-frequency bipolar bursts of electrical pulses. Biochim Biophys Acta. 2016;1858(11):2689–2698.
   PubMed Web of Science ®Google Scholar
• Aycock KN, Zhao Y, Lorenzo MF, et al. A theoretical argument for extended interpulse delays in therapeutic high-frequency irreversible electroporation treatments. IEEE Trans Biomed Eng. 2021. DOI:https://doi.org/10.1109/TBME.2021.3049221
   PubMed Web of Science ®Google Scholar
• Zhang W, Van Luttervelt C. Toward a resilient manufacturing system. CIRP Ann. 2011;60(1):469–472.
   Web of Science ®Google Scholar
• Zhang B, Moser MA, Zhang EM, et al. A new approach to feedback control of radiofrequency ablation systems for large coagulation zones. Int J Hyperth. 2017;33(4):367–377.
   PubMed Web of Science ®Google Scholar
• Zhang W, Wang J, Lin Y. Integrated design and operation management for enterprise systems. Enterp Inf Sys.; 2019;13(4):424–429.
   Google Scholar