199
Views
1
CrossRef citations to date
0
Altmetric
Original Articles

Functional analysis of high-content high-throughput imaging data

, , &
Pages 1903-1919 | Received 04 Nov 2015, Accepted 14 Sep 2016, Published online: 30 Sep 2016

References

  • N. Coffey and J. Hinde, Analyzing time-course microarray data using functional data analysis – a review, Stat. Appl. Genet. Mol. Biol. 10 (2011), pp. 1–32.
  • J.A. Cuesta-Albertos and M. Febrero-Bande, A simple multiway anova for functional data, Test 19 (2010), pp. 537–557. doi: 10.1007/s11749-010-0185-3
  • A. Cuevas, M. Febrero, and R. Fraiman, An anova test for functional data, Comput. Statist. Data Anal. 47 (2004), pp. 111–122. doi: 10.1016/j.csda.2003.10.021
  • P. Denner, J. Schmalowsky, and S. Prechtl, High-content analysis in preclinical drug discovery, Comb. Chem. High Throughput Screen. 11 (2008), pp. 216–230. doi: 10.2174/138620708783877780
  • Y. Feng, T.J. Mitchison, A. Bender, D.W. Young, and J.A. Tallarico, Multi-parameter phenotypic profiling: Using cellular effects to characterize small-molecule compounds, Nat. Rev. Drug Discov. 8 (2009), pp. 567–578. doi: 10.1038/nrd2876
  • P. Gans and J.B. Gill, Smoothing and differentiation of spectroscopic curves using spline functions, Appl. Spectrosc. 38 (1984), pp. 370–376. doi: 10.1366/0003702844555511
  • G.H. Golub, M. Heath, and G. Wahba, Generalized cross-validation as a method for choosing a good ridge parameter, Technometrics 21 (1979), pp. 215–223. doi: 10.1080/00401706.1979.10489751
  • P. Good, Permutation Tests: A Practical Guide to Resampling Methods for Testing Hypotheses, Springer, New York, 2000.
  • A. Kümmel, P. Selzer, M. Beibel, H. Gubler, C.N. Parker, and D. Gabriel, Comparison of multivariate data analysis strategies for high-content screening, J. Biomol. Screen. 16 (2011), pp. 338–347. doi: 10.1177/1087057110395390
  • P. Lang, K. Yeow, A. Nichols, and A. Scheer, Cellular imaging in drug discovery, Nat. Rev. Drug Discov. 5 (2006), pp. 343–356. doi: 10.1038/nrd2008
  • L.-H. Loo, L.F. Wu, and S.J. Altschuler, Image-based multivariate profiling of drug responses from single cells, Nat. Methods 4 (2007), pp. 445–453.
  • E.P. MacCarthy and S.S. Bloomfield, Labetalol: A review of its pharmacology, pharmacokinetics, clinical uses and adverse effects, Pharmacotherapy 3 (1983), pp. 193–217. doi: 10.1002/j.1875-9114.1983.tb03252.x
  • A. Nichols, High content screening as a screening tool in drug discovery, Methods Mol. Biol 356 (2007), pp. 379–387.
  • Z.E. Perlman, M.D. Slack, Y. Feng, T.J. Mitchison, L.F. Wu, and S.J. Altschuler, Multidimensional drug profiling by automated microscopy, Science 306 (2004), pp. 1194–1198. doi: 10.1126/science.1100709
  • R Core Team, R: A Language and Environment for Statistical Computing, R Foundation for Statistical Computing, Vienna, Austria, 2014.
  • J.O. Ramsay and B.W. Silverman, Functional Data Analysis, Springer, New York, 2005.
  • J.O. Ramsay, S. Graves, and G. Hooker, Functional Data Analysis with R and MATLAB, Springer, New York, 2009.
  • J.O. Ramsay and B.W. Silverman, Applied Functional Data Analysis: Methods and Case Studies, Springer, New York, 2002.
  • F. Scheipl, A.-M. Staicu, and S. Greven, Functional additive mixed models, J. Comput. Graph. Statist. 24 (2015), pp. 477–501. doi: 10.1080/10618600.2014.901914
  • D.L. Taylor, J.R. Haskins, and K.A. Giuliano, High Content Screening: A Powerful Approach to Systems Cell Biology and Drug Discovery, Humana Press, Totowa, NJ, 2006.
  • S. Wink, S. Hiemstra, S. Huppelschoten, E. Danen, M. Niemeijer, G. Hendriks, H. Vrieling, B. Herpers, and B. van de Water, Quantitative high content imaging of cellular adaptive stress response pathways in toxicity for chemical safety assessment, Chem. Res. Toxicol. 27 (2014), pp. 338–355. doi: 10.1021/tx4004038
  • N. Zumel, J. Mount, and J. Porzak, Practical Data Science with R, Manning, Shelter Island, 2014.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.