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Original Article

Activity of cilofungin (LY 121019), a new lipopeptide antibiotic, on the cell wall and cytoplasmic membrane of Candida albicans. Structural modifications in scanning and transmission electron microscopy

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Pages 425-436 | Accepted 27 Jun 1990, Published online: 09 Jul 2009

REFERENCES

  • Baguly E.E., Rommele C., Gruneco J., Weheli W. Papulacandin B: an inhibitor of glucan synthesis in yeast spheroplast. European Journal of Biochemistry 1979; 97: 345–351
  • Benz F., Knusel F., Nuesch J. Echinocandin B, ein neuartiges polypetid antibiotikum aus Aspergillus nidulans var. echinulatus. Isolierung und bausteine. Helvetica Chimica Acta 1974; 57: 2459–2477
  • Bonaly R., Dari L., Kubiak C., Lejeune J., Poulain D. Altérations des parois de Candida albicans cultivées en présence de doses subléthales de nystatine. Annales de l'Institut Pasteur Microbiologie 1985; 136B: 181–193
  • Borgers M. Ultrastructural correlates of antimycotic treatment. Current Topics in Medical Mycology, M.R. McGinnis. Springer-Verlag, New York 1988; Vol. 2: 1–39, In
  • Bozzola J.J., Mehta R.J., Nisbet L.J., Valenta J.R. The effect of aculeacin A and papulacandin B on morphology and cell wall ultrastructure in Candida albicans. Canadian Journal of Microbiology 1984; 30: 857–863
  • Cabib E., Roberts R., Bowers B. Synthesis of the yeast cell wall and its regulation. Annual Review of Biochemistry 1982; 51: 763–793
  • Cassone A. Cell wall of Candida albicans: its function and its impact on the host. Current Topics in Medical Mycology, M.R. McGinnis, M. Borgers. Springer-Verlag, New York 1989; Vol. 3: 248–314, In
  • Cassone A., Mason R., Kerridge D. Lysis of growing yeast form cells of Candida albicans by echinocandin. A cytological study. Sabouraudia 1981; 19: 97–110
  • Cassone A., Simonetti N., Strippoli V. Ultrastructural changes in the wall during germtube formation from blastospores of Candida albicans. Journal of General Microbiology 1973; 77: 417–420
  • Debono M., Abbott B.J., Turner J.R., Howard L.C., Gordee R.S., Hunt A.S., Barnhart M., Molloy M., Willard K.E., Fukuda D., Butler T.F., Zeckner D.J. Synthesis and evaluation of LY 121019, a member of a series of semisynthetic analogues of the antifungal lipopeptide echinocandin B. Annales of the New York Academy of Sciences 1988; 544: 152–167
  • Fungal Antigens, E. Drouhet, G. Cole, L. de Repentigny, J.P. Latge, B. Dupont. Plenum Press, New York 1988
  • Drouhet E., Dupont B., Improvisi L. Antifungal activity of a new semi-biosynthetic antifungal agent (LY 121019). Sensitivity of Candida albicans strains from AIDS patients and resistant strains to various antifungal agents. 28th International Conference on Antimicrobial Agents and Chemotherapy, Los Angeles, 1988; 379–379, Abstract No. 511
  • Drouhet E., Dupont B., Improvisi L., Lesourd M., Prevost M.C. La cilofungine (LY 121019), nouvel antifongique lipopolypeptidique agissant sur la paroi fongique. Activité in vitro sur les levures. Bulletin de la Société Française de Mycologie Médicale 1989; 18: 31–46
  • Drouhet E., Dupont B., Improvisi L., Viviani M.A., Tortorano A.M. Disc agar diffusion and microplate automatized technics for in vitro evaluation of antifungal agents on yeasts and sporulated pathogenic fungi. In vitro and in vivo evaluation of antifungal agents, K. Iwata, H. Vanden Bossche. Elsevier Science Publ. B.V., Amsterdam 1986; 31–49, In
  • Fleet G.M. Composition and structure of yeast cell walls. Current Topics in Medical Mycology, M.R. McGinnis. Springer-Verlag, New York 1985; Vol. 1: 24–56, In
  • Garzon S., Marquis G., Kurstak E., Montplaisir S., Benhamou N. Antigenic structure of Candida albicans. Electron microscopic localization of polysaccharide and immunodeterminants in the cell wall. Immunology of Fungal Diseases, E. Kurstak. Marcel Dekker, New York 1989; 3–36, In
  • Gopal P.K., Shepherd M.G., Sullivan P.A. Analysis of wall glucans from yeast, hyphal and germ tube forming cells of Candida albicans. Journal of General Microbiology 1984; 130: 3295–3300
  • Gordee R.S., Zeckner D.J., Alborn W.E., Jr. Action of LY 121019 on Candida albicans cell wall biosynthesis. 27th International Conference on Antimicrobial Agents and Chemotherapy, New York, 1987; 267–267, Abstract 977
  • Gordee R.S., Zeckner D.J., Ellis L.F., Thakkar A.L., Howard L.C. In vitro and in vivo anti-Candida activity and toxicology of LY 121019. Journal of Antibiotics 1984; 37: 1054–1065
  • Gordee R.S., Zeckner D.J., Howard L.C., Alborn W.E., Jr, Debono M. Anti-Candida activity and toxicology of LY 121019, a novel semisynthetic polypeptide antifungal antibiotic. Annales of the New York Academy of Sciences 1988; 544: 294–309
  • Hobbs M., Perfect J., Durack D. Evaluation of in vitro antifungal activity of LY 121019. European Journal of Clinical Microbiology and Infectious Diseases 1988; 7: 77–80
  • Iwata K.Y., Yamamoto H., Yamaguchi H., Hiratani T. In vitro studies of aculeacin A, a new antifungal antibiotic. Journal of Antibiotics 1982; 35: 203–209
  • Mehta R.J., Nash C.H., Grappel S.F., Actor P. Aculeacin A resistant mutants of Candida albicans. JOurnal of Antibotics 1982; 35: 707–711
  • Melchinger W., Muller J. Studies on the in vitro sensitivity of yeast strains isolated from clinical specimens to LY 121019, a new antifungal agent. Mykosen 1987; 30: 605–608
  • Mizoguchi J., Saito T., Mizuno K., Hayano K. On the mode of action of a new antifungal antibiotic, aculeacin A: inhibition of cell wall synthesis in Saccharomyces cerevisiae. Journal of Antibiotics 1977; 30: 308–313
  • Mizuno K., Yagi A., Satoi S., Takada M., Hayashi M., Asano K., Matsuda T. Studies on aculeacin I. Isolation and characterization of aculeacin A. Journal of Antibiotics 1977; 30: 297–302
  • Muller J. Activité in vivo de la cilofungine (LY 121019), dérivé d'échinocandine. Bulletin de la Société Française de Mycologie Médicale 1989; 18: 47–50
  • Muller J., Scheidecker I. Immunoelectronmicroscopic studies on the influence of an echinocandin B analog on the cell wall antigenicity of Candida albicans. Poster. 10th Congress International Society of Human and Animal Mycology. ISHAM, Barcelona 1988
  • Murgui A., Elorza M.V., Sentandreu R. Effect of papulacandin B and calcofluor white on the incorporation of mannoproteins in the wall of Candida albicans blastospores. Biochimica et Biophysica Acta 1985; 841: 215–222
  • Murgui A., Elorza M.V., Sentandreu R. Tunicamycin and papulacandin B inhibit incorporation of specific mannoproteins into the wall of Candida albicans regenerating protoplasts. Biochimica et Biophysica Acta 1986; 885: 550–558
  • Odds F.C. Candida and Candidosis. A Review and Bibliography2nd edn. Ballière-Tindall, London 1988
  • Orlean P.A.B. 1,3-β-D-glucan synthetase from budding and filamentous cultures of the dimorphic fungus Candida albicans. European Journal of Biochemistry 1982; 127: 397–403
  • Perez P., Varona R., Garcia-Acha I. Effect of papulacandin B and aculeacin A on β-(1,3) glucan-synthase from Geotrichum lactis. FEBS Letters 1981; 129: 249–252
  • Ruiz-Herrera J., Sentandreu R. Fungal cell wall synthesis and assembly. Current Topics in Medical Mycology, M.R. McGinnis, M. Borgers. Springer-Verlag, New York 1989; Vol. 3: 168–217, In
  • Sawitowska-Schroder E.T., Kerridge D., Perry H. Echinocandin inhibition of 1,3-β-D-glucan synthase from Candida albicans. FEBS Letters 1984; 173: 134–138
  • Scherwitz C., Martin R., Ueberberg H. Ultrastructural investigations of the formation of Candida albicans germ tubes and septa. Sabouraudia 1978; 16: 115–124
  • Shematek E.M., Broatz J.A., Cabib E. Biosynthesis of the yeast cell wall. I. Preparation and properties of a β(1,3) glucan synthetase. Journal of Biological Chemistry 1980; 255: 888–894
  • Shematek E.M., Cabib E. Biosynthesis of the yeast cell wall. II. Regulation of β(1,3) glucan synthetase by ATP and GTP. Journal of Biological Chemistry 1980; 255: 895–902
  • Shepherd M.G. Cell envelope of Candida albicans. CRC Critical Reviews in Microbiology 1987; 15: 7–25
  • Shepherd M.G. Morphogenetic transformation of fungi. Current Topics in Medical Mycology, M.R. McGinnis. Springer-Verlag, New York 1988; Vol. 2: 278–304, In
  • Strippoli V., D'Auria E.D., Simonetti N. A study of the antifungal activity of LY 121019, a new echnocandin derivative. Chemioterapia 1988; 7: 33–37
  • Sullivan P.A., Chiew Y.Y., Molloy C., Templeton M.D., Shepherd M.G. An analysis of the metabolism and cell wall composition of Candida albicans during germ-tube formation. Canadian Journal of Microbiology 1983; 29: 1514–1525
  • Surarit R., Shepherd M.G. The effects of azole and polyene antifungals on the plasma membrane enzymes of Candida albicans. Journal of Medical and Veterinary Mycology 1987; 25: 403–413
  • Taft C.S., Stark T., Selitrennikoff C.P. Cilofungin (LY 121019) inhibits Candida albicans (1,3)-β-glucan synthase activity. Antimicrobial Agents and Chemotherapy 1988; 32: 1901–1903
  • Traxles P., Gruner J., Auden J.A.L. Papulacandin, a new family with antifungal activity. I. Fermentation, isolation, chemical and biological characterization of papulacandin A, B, C, D and E. Journal of Antibiotics 1977; 30: 289–296
  • Vanden Bossche H. Importance and role of sterols in fungal membranes. Biochemistry of Cell Walls and Membranes in Fungi, P.J. Kuhn, A.P.J. Trinci, M.J. Jung, M.W. Goosey, L.G. Copping. Springer-Verlag, Berlin 1990; 135–157, In
  • Vanden Bossche H., Willemsens G., Marichal P. Anti-Candida drugs. The biochemical basis for their activity. CRC Critical Reviews in Microbiology 1987; 15: 57–72
  • Yamaguchi H., Hiratani T., Baba M., Osumi M. Effect of aculeacin A, a wall-active antibiotic, on synthesis of the yeast cell wall. Microbiology and Immunology 1985; 29: 609–623
  • Yamaguchi H., Hiratani T., Iwata K., Yamamoto Y. Studies on the mechanism of antifungal action of aculeacin A. Journal of Antibiotics 1982; 35: 210–219

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