A preliminary study of the efficacy of ondansetron in the treatment of ataxia, poor balance and incoordination from brain injury

References

• WILDE, M. and MARKHAM, A.: Ondansetron: a review of its pharmacology and preliminary clinical findings in novel applications. Drugs, 52: 773–794, 1996.
   PubMed Web of Science ®Google Scholar
• VAN WOERT, M. H., PLAITAICIS, A., HWANG, E. C. et al.: Effect of thiamine deficiency on brain serotonin turnover. Brain Research, 138: 103–110, 1979.
   Google Scholar
• PLAITAICIS, A., VAN WOERT, M. H., HWANG, E. C. et al.: The effect of acute thiamine deficiency on brain tryptophan, seratonin and 5-hydroxyindoleacetic acid. Journal of Neurochemistry, 3: 1087–1089, 1978.
   Google Scholar
• TROUILLAS, P., SERRATRICE, G., LAPLANE, D. et al.: Levorotary from of 5-hydroxytryptophan in Friedreich's ataxia. Archives of Neurology, 52: 456–460, 1995.
   Google Scholar
• TROUILLAS, P., Xm, J., ADELEINE, P. et al.: Buspirone, a 5-hydroxytryptamine 1A agonist is active in cerebellar ataxia: results of a double-blind drug placebo study in patients with cerebellar cortical atrophy. Archives of Neurology, 54: 749–752, 1997.
   Google Scholar
• RicE, G. P. A. and EBERs, G. C.: Ondansetron for intractable vertigo complicating acute brainstem disorders. Lancet, 345: 1182–1183, 1995.
   Google Scholar
• Ric: Ondansetron, a 5-HT3 antagonist, improves cerebellar tremor. Journal of Neurology, Neurological Surgery and Psychiatry, 62: 282–284, 1997.
   PubMedGoogle Scholar
• SIROTA, P., MOSHEVA, T., SHABTAY, H. et al.: Use of the selective serotonin 3 receptor antagonist ondansetron in the treatment of neuroleptic-induced tardive dyskinesia. American Journal of Psychiatry, 157: 287–289, 2000.
   Google Scholar
• Lou, J. S., GOLDFARB, L., MCSHANE, L. et al.: Use of buspirone for treatment of cerebellar ataxia. Archives of Neurology, 52: 982–988, 1995.
   PubMedGoogle Scholar
• Compendium of Pharmaceuticals and Specialities, 35th edn, pp. 1797–1780, 2000, published by The Canadian Drug Reference for Professionals. Canadian Pharmacists Assoc, Editor in Chief, Carol Repchinsky.
   Google Scholar
• BACICMAN, C. L., HARRis, S. R., CHisHoun, J. A., MONETTE, A. D.: Single-subject research in rehabilitation. A review. Archives of Physical Medicine and Rehabilitation, 78: 1145–1153, 1997.
   Google Scholar
• AmERICAN GUIDANCE SERVICE: INC, 'The Minnesota Rate of Manipulation Tests-Examiner's Manual' (Circle Pines, Minnesota: American Guidance Service), 1969.
   Google Scholar
• TIFFIN, J.: Purdue Pegboard Examiner Manual (Science Research Associates), 1948.
   Google Scholar
• FUGL-MEYER, A. R., JAASKO, I., LEYMAN, I. et al.: The post stroke henniplegic patient I: a method for evaluation of physical performance. Scandinavian Journal of Rehabilitation Medicine, 7: 13–31, 1975.
   Google Scholar
• PRIETO, T. E., MYKLEBUST, J. B., HOFFMANN, R. G., LOVETT, E. G., MYKLEBUST, E. G.: Measures of postural steadiness: differences between healthy young and elderly adults. 43: 956–966, 1996.
   Google Scholar
• BERG, K., WOOD-DAUPHINEE, S., WILLIAMS et al.: Measuring balance in the elderly: preliminary development of an instrument. Physiotherapy Canada, 41: 304–311, 1989.
   Google Scholar
• BERG, K., WOOD-DAUPHINEE, S. and WILLIAMS, J.: The balance scale: reliability assessment for elderly residents and patients with an acute stroke. Scandinavian Journal of Rehabilitation Medicine, 27: 27–36, 1995.
   Google Scholar
• BERG, K., WOOD-DAUPHINEE, S. and WILLIAMS, J.: Measuring balance in the elderly: validation of an instrument. Canadian Journal of Public Health, 83 (Suppl 2): S7-11, 1992.
   Google Scholar
• BERG, K., MAICI, B. and WILLIAMS, J.: Clinical and laboratory measures of postural balance in the elderly population. Archives of Physical Medicine and Rehabilitation, 73: 1073–1080, 1992.
   PubMed Web of Science ®Google Scholar
• HOBART, J. C.: Evidence-based measurement: which disability scale for neurologic rehabilitation? Neurology, 57: 639–644, 2001.
   Google Scholar
• GRANGER, C. V., HAMILTON, B. B., KEITH, R. A. et al.: Advances in functional assessment for medical rehabilitation. Top Geriatric Rehabilitation, 1: 59–74, 1986.
   Google Scholar
• CI-IARULUXANANAN, S., SOMBOONVIBOON, W., KYOKONG, O. et al.: Ondansetron for treatment of intrathecal morphine-induced pruritis after cesarean delivery. Registered Anesthesia and Pain Medicine, 25: 535–539, 2000.
   PubMedGoogle Scholar
• BAYINDIR, O., GUNDEN, M., AICPINAR, B. et al.: Ondansetron hydrochloride for the treatment of delirium after coronary artery surgery. Journal of Thoracic Cardiovascular Surgery, 121: 176–177, 2001.
   PubMedGoogle Scholar
• BAYINDIR, O., AKPINAR., B., CAN, E. et al.: The use of the 5-HT3-receptor antagonist ondansetron for the treatment of postcardiotomy delirium. Journal of Cardiovascular Anesthesia, 14: 288–292, 2000.
   Google Scholar
• BROOCKS, A., PIGOTT, J. A., HILL, J. L., CANTER, S., GRADY, T. A., L'HEuREux, F., MURPHY, D. L.: Acute intravenous administration of ondansetron and m-CPP, alone and in combination, in patients with OCD: behavioral and biological results. Psychiatry Research, 79: 11–20, 1998.
   Google Scholar
• FREEMAN, A. M., WESTPHAL, J. R., NoRRis, G. T., RoGGERo, B. A., WEBB, P. B., FREEmAN, K. L., RUSH, J. A., HEARNE„ E. M. 3rd: Efficacy of ondansetron in the treatment of generalized anxiety disorder. Depression & Anxiety, 79: 11–20, 1998.
   Google Scholar
• WOOD-DAUPHINEE, S., BERG, K., BRAVO, G. et al.: The balance scale: responding to clinically meaningful changes. Canadian Journal of Rehabilitation, 10: 35–50, 1997.
   Google Scholar