385
Views
20
CrossRef citations to date
0
Altmetric
Original Articles

Blood biomarkers indicate mild neuroaxonal injury and increased amyloid β production after transient hypoxia during breath-hold diving

, , , , , , & show all
Pages 1226-1230 | Received 10 Sep 2015, Accepted 14 Apr 2016, Published online: 07 Jul 2016

References

  • Baugh CM, Stamm JM, Riley DO, Gavett BE, Shenton ME, Lin A, Nowinski CJ, Cantu RC, McKee AC, Stern RA. Chronic traumatic encephalopathy: neurodegeneration following repetitive concussive and subconcussive brain trauma. Brain Imaging & Behavior 2012;6:244–254.
  • Smith DH, Chen XH, Nonaka M, Trojanowski JQ, Lee VM, Saatman KE, Leoni MJ, Xu BN, Wolf JA, Meaney DF. Accumulation of amyloid beta and tau and the formation of neurofilament inclusions following diffuse brain injury in the pig. Journal of Neuropathology & Experimental Neurology 1999;58:982–992.
  • Wang HC, Sun CF, Chen H, Chen MS, Shen G, Ma YB, Wang BD. Where are we in the modelling of traumatic brain injury? Models complicated by secondary brain insults. Brain Injury 2014;28:1491–1503.
  • Parilkh U, Williams M, Lapidus J, Pineda J, Brody D, Friess S. 6: delayed hypoxemia following traumatic brain injury exacerbates axonal injury. Critical Care Medicine 2015;43:2.
  • McHugh GS, Engel DC, Butcher I, Steyerberg EW, Lu J, Mushkudiani N, Hernandez AV, Marmarou A, Maas AI, Murray GD. Prognostic value of secondary insults in traumatic brain injury: results from the IMPACT study. Journal of Neurotrauma 2007;24:287–293.
  • Xie Y, Yao Z, Chai H, Wong WM, Wu W. Potential roles of Alzheimer precursor protein A4 and beta-amyloid in survival and function of aged spinal motor neurons after axonal injury. Journal of Neuroscience Research 2003;73:557–564.
  • Blennow K, de Leon MJ, Zetterberg H. Alzheimer’s disease. Lancet 2006;368:387–403.
  • Sun X, He G, Qing H, Zhou W, Dobie F, Cai F, Staufenbiel M, Huang LE, Song W. Hypoxia facilitates Alzheimer’s disease pathogenesis by up-regulating BACE1 gene expression. Proceedings of the National Academy of Sciences USA 2006;103:18727–18732.
  • Jendroska K, Poewe W, Daniel SE, Pluess J, Iwerssen-Schmidt H, Paulsen J, Barthel S, Schelosky L, Cervos-Navarro J, DeArmond SJ. Ischemic stress induces deposition of amyloid beta immunoreactivity in human brain. Acta Neuropathologica 1995;90:461–466.
  • Zetterberg H, Mortberg E, Song L, Chang L, Provuncher GK, Patel PP, Ferrell E, Fournier DR, Kan CW, Campbell TG, et al. Hypoxia due to cardiac arrest induces a time-dependent increase in serum amyloid beta levels in humans. PLoS One 2011;6:e28263.
  • Qi JP, Wu H, Yang Y, Wang DD, Chen YX, Gu YH, Liu T. Cerebral ischemia and Alzheimer’s disease: the expression of amyloid-beta and apolipoprotein E in human hippocampus. Journal of Alzheimers Disease 2007;12:335–341.
  • Qiu C, Winblad B, Fratiglioni L. The age-dependent relation of blood pressure to cognitive function and dementia. The Lancet Neurology 2005;4:487–499.
  • Kalaria RN, Ballard C. Overlap between pathology of Alzheimer disease and vascular dementia. Alzheimers Disease & Associated Disorders 1999;13(Suppl 3):S115–123.
  • Osorio RS, Gumb T, Pirraglia E, Varga AW, Lu SE, Lim J, Wohlleber ME, Ducca EL, Koushyk V, Glodzik L, et al. Sleep-disordered breathing advances cognitive decline in the elderly. Neurology 2015;84:1964–1971.
  • Yaffe K, Laffan AM, Harrison SL, Redline S, Spira AP, Ensrud KE, Ancoli-Israel S, Stone KL. Sleep-disordered breathing, hypoxia, and risk of mild cognitive impairment and dementia in older women. Journal of the American Medical Association 2011;306:613–619.
  • Blackwell T, Yaffe K, Laffan A, Redline S, Ancoli-Israel S, Ensrud KE, Song Y, Stone KL, Osteoporotic Fractures in Men Study G. Associations between sleep-disordered breathing, nocturnal hypoxemia, and subsequent cognitive decline in older community-dwelling men: the osteoporotic fractures in men sleep study. Journal of the American Geriatric Society 2015;63:453–461.
  • Bu XL, Liu YH, Wang QH, Jiao SS, Zeng F, Yao XQ, Gao D, Chen JC, Wang YJ. Serum amyloid-beta levels are increased in patients with obstructive sleep apnea syndrome. Scientific Reports 2015;5:13917.
  • Thomas T, Thomas G, McLendon C, Sutton T, Mullan M. beta-Amyloid-mediated vasoactivity and vascular endothelial damage. Nature 1996;380:168–171.
  • Niwa K, Porter VA, Kazama K, Cornfield D, Carlson GA, Iadecola C. A beta-peptides enhance vasoconstriction in cerebral circulation. American Journal of Physiology & Heart Circulation Physiology 2001;281:H2417–2424.
  • Bell RD, Deane R, Chow N, Long X, Sagare A, Singh I, Streb JW, Guo H, Rubio A, Van Nostrand W, et al. SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells. Nature Cell Biology 2009;11:143–153.
  • Ferretti G, Costa M, Ferrigno M, Grassi B, Marconi C, Lundgren CE, Cerretelli P. Alveolar gas composition and exchange during deep breath-hold diving and dry breath holds in elite divers. Journal of Applied Physiology (1985) 1991;70:794–802.
  • Craig AB Jr., Medd WL. Oxygen consumption and carbon dioxide production during breath-hold diving. Journal of Applied Physiology 1968;24:190–202.
  • Blennow K, Zetterberg H. Understanding biomarkers of neurodegeneration: Ultrasensitive detection techniques pave the way for mechanistic understanding. Nature Medicine 2015;21:217–219.
  • Friede RL, Samorajski T. Axon caliber related to neurofilaments and microtubules in sciatic nerve fibers of rats and mice. Anatomical Record 1970;167:379–387.
  • Trojanowski JQ, Schuck T, Schmidt ML, Lee VM. Distribution of tau proteins in the normal human central and peripheral nervous system. Journal of Histochemistry & Cytochemistry 1989;37:209–215.
  • Olsson B, Zetterberg H, Hampel H, Blennow K. Biomarker-based dissection of neurodegenerative diseases. Progress in Neurobiology 2011;95:520–534.
  • Zetterberg H, Smith DH, Blennow K. Biomarkers of mild traumatic brain injury in cerebrospinal fluid and blood. Nature Reviews Neurology 2013;9:201–210.
  • Zongo D, Ribereau-Gayon R, Masson F, Laborey M, Contrand B, Salmi LR, Montaudon D, Beaudeux JL, Meurin A, Dousset V, et al. S100-B protein as a screening tool for the early assessment of minor head injury. Annals Emergency Medicine 2012;59:209–218.
  • Rissin DM, Kan CW, Campbell TG, Howes SC, Fournier DR, Song L, Piech T, Patel PP, Chang L, Rivnak AJ, et al. Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations. Nature Biotechnology 2010;28:595–599.
  • Neselius S, Zetterberg H, Blennow K, Randall J, Wilson D, Marcusson J, Brisby H. Olympic boxing is associated with elevated levels of the neuronal protein tau in plasma. Brain Injury 2013;27:425–433.
  • Randall J, Mortberg E, Provuncher GK, Fournier DR, Duffy DC, Rubertsson S, Blennow K, Zetterberg H, Wilson DH. Tau proteins in serum predict neurological outcome after hypoxic brain injury from cardiac arrest: results of a pilot study. Resuscitation 2012;8:351–356.
  • Mondello S, Buki A, Barzo P, Randall J, Provuncher G, Hanlon D, Wilson D, Kobeissy F, Jeromin A. CSF and plasma amyloid-beta temporal profiles and relationships with neurological status and mortality after severe traumatic brain injury. Scientific Report 2014;4:6446.
  • Jessen NA, Munk AS, Lundgaard I, Nedergaard M. The Glymphatic System: A Beginner’s Guide. Neurochemical Research 2015;40:2583–2599.
  • Iliff JJ, Chen MJ, Plog BA, Zeppenfeld DM, Soltero M, Yang L, Singh I, Deane R, Nedergaard M. Impairment of glymphatic pathway function promotes tau pathology after traumatic brain injury. Journal of Neuroscience 2014;34:16180–16193.
  • Shahim P, Tegner Y, Wilson DH, Randall J, Skillback T, Pazooki D, Kallberg B, Blennow K, Zetterberg H. Blood biomarkers for brain injury in concussed professional ice hockey players. JAMA Neurology 2014;71:684–692.
  • Shahim P, Mansson JE, Darin N, Zetterberg H, Mattsson N. Cerebrospinal fluid biomarkers in neurological diseases in children. European Journal of Paediatric Neurology 2013;17:7–13.
  • Erecinska M, Silver IA. Tissue oxygen tension and brain sensitivity to hypoxia. Respiratory Physiology 2001;128:263–276.
  • Kann O, Papageorgiou IE, Draguhn A. Highly energized inhibitory interneurons are a central element for information processing in cortical networks. Journal of Cerebral Blood Flow & Metabolism 2014;34:1270–1282.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.