185
Views
2
CrossRef citations to date
0
Altmetric
Original Articles

Early post-haemorrhagic stroke testosterone and oestradiol levels and long-term risk of death

, , , , &
Pages 401-405 | Received 24 May 2016, Accepted 23 Nov 2016, Published online: 16 Feb 2017

References

  • Schneider HJ, Kreitschmann-Andermahr I, Ghigo E, Stalla GK, Agha A. Hypothalamopituitary dysfunction following traumatic brain injury and aneurysmal subarachnoid hemorrhage: a systematic review. JAMA. 2007;298:1429–1438.
  • Kreitschmann-Andermahr I, Hoff C, Saller B, Niggemeier S, Pruemper S, Hutter BO, Rohde V, Gressner A, Matern S, Gilsbach JM. Prevalence of pituitary deficiency in patients after aneurysmal subarachnoid hemorrhage. J Clin Endocrinol Metab. 2004;89:4986–4992.
  • Dimopoulou I, Kouyialis AT, Tzanella M, Armaganidis A, Thalassinos N, Sakas DE, Tsagarakis S. High incidence of neuroendocrine dysfunction in long-term survivors of aneurysmal subarachnoid hemorrhage. Stroke. 2004;35:2884–2889.
  • Fassbender K, Schmidt R, Mossner R, Daffertshofer M, Hennerici M. Pattern of activation of the hypothalamic-pituitary-adrenal axis in acute stroke. Relation to acute confusional state, extent of brain damage, and clinical outcome. Stroke. 1994;25:1105–1108.
  • Bondanelli M, De Marinis L, Ambrosio MR, Monesi M, Valle D, Zatelli MC, Fusco A, Bianchi A, Farneti M, degli Uberti EC. Occurrence of pituitary dysfunction following traumatic brain injury. J Neurotrauma. 2004;21:685–696.
  • Klose M, Juul A, Poulsgaard L, Kosteljanetz M, Brennum J, Feldt-Rasmussen U. Prevalence and predictive factors of post-traumatic hypopituitarism. Clin Endocrinol (Oxf). 2007;67:193–201.
  • Katsiki N, Ntaios G, Vemmos K. Stroke, obesity and gender: a review of the literature. Maturitas. 2011;69:239–243.
  • Persky RW, Turtzo LC, McCullough LD. Stroke in women: disparities and outcomes. Curr Cardiol Rep. 2010;12:6–13.
  • Cheng J, Alkayed NJ, Hurn PD. Deleterious effects of dihydrotestosterone on cerebral ischemic injury. J Cereb Blood Flow Metab. 2007;27:1553–1562.
  • Razmara A, Krause DN, Duckles SP. Testosterone augments endotoxin-mediated cerebrovascular inflammation in male rats. Am J Physiol Heart Circ Physiol. 2005;289:H1843–H1850.
  • Anderson JL, May HT, Lappé DL, Bair T, Le V, Carlquist JF, Muhlestein JB. Impact of testosterone replacement therapy on myocardial infarction, stroke, and death in men with low testosterone concentrations in an integrated health care system. Am J Cardiol. 2016;1117:794–799.
  • Al-Khazaali A, Arora R, Muttar S. Controversial effects of exogenous testosterone on cardiovascular diseases. Am J Ther. 2016;23:e1504–e1513.
  • Morgentaler A, Miner MM, Caliber M, Guay AT, Khera M, Traish AM. Testosterone therapy and cardiovascular risk: advances and controversies. Mayo Clin Proc. 2015;90:224–251.
  • dos Santos RL, da Silva FB, Ribeiro RF Jr, Stefanon I. Sex hormones in the cardiovascular system. Horm Mol Biol Clin Investig. 2014;18:89–103.
  • Mendelsohn ME, Karas RH. Estrogen and the blood vessel wall. Curr Opin Cardiol. 1994;9:619–626.
  • Farhat MY, Abi-Younes S, Ramvell PW. Non-genomic effects of estrogen and the vessel wall. Biochem Pharmacol. 1996;51:571–576.
  • Das A, Smith JA, Gibson C, Varma AK, Ray SK, Banik NL. Estrogen receptor agonists and estrogen attenuate TNF-alpha induced apoptosis in VSC4.1 motoneurons. J Endocrinol. 2011;208:171–182.
  • Tenenbaum M, Azab AN, Kaplanski J. Effects of estrogen against LPS-induced inflammation and toxicity in primary rat glial and neuronal cultures. J Endotoxin Res. 2007;13:158–166.
  • Suzuki S, Brown CM, Wise PM. Neuroprotective effects of estrogens following ischemic stroke. Front Neuroendocrinol. 2009;30:201–211.
  • Nakamura T, Hua Y, Keep RF, Park JW, Xi G, Hoff JT. Estrogen therapy for experimental intracerebral hemorrhage in rats. J Neurosurg. 2005;103:97–103.
  • Gu Y, Xi G, Liu W, Keep RF, Hua Y. Estrogen reduces iron-mediated brain edema and neuronal death. Acta Neurochir Suppl. 2010;106:159–162.
  • Nakamura T, Xi G, Keep RF, Wang M, Nagao S, Hoff JT, Hua Y. Effects of endogenous and exogenous estrogen on intracerebral hemorrhage-induced brain damage in rats. Acta Neurochir Suppl. 2006;96:218–221.
  • Zheng Y, Hu Q, Manaenko A, Zhang Y, Peng Y, Xu L, Tang J, Tang J, Zhang JH. 17β-Estradiol attenuates hematoma expansion through estrogen receptor α/silent information regulator 1/nuclear factor-kappa b pathway in hyperglycemic cerebral hemorrhage mice. Stroke. 2015;46:485–491.
  • Sharma R, Oni OA, Gupta G, Sharma M, Dawn B, Sharma R, Parashara D, Savin VJ, Ambrose JA, Barua RS. Normalization of testosterone level is correlated with reduced incidence of myocardial infarction and mortality in men. Eur Heart J. 2015;36:2706–2715.
  • Graeb DA, Robertson WD, Lapointe JS, Nugent RA, Harrison PB. Compound tomographic diagnosis of intraventricular hemorrhage. Etiology and prognosis. Radiology. 1982;143:91–96.
  • Hemphill JC 3rd, Bonovich DC, Besmertis L, Manley GT, Johnston SC. The ICH score: a simple, reliable grading scale for intracerebral hemorrhage. Stroke. 2001;32:891–897.
  • Kothari RU, Brott T, Broderick JP, Barsan WG, Sauerbeck LR, Zuccarello M, Khoury J. The ABCs of measuring intracerebral hemorrhage volumes. Stroke. 1996;27:1304–1307.
  • Chen TY, Tsai KL, Lee TY, Chiueh CC, Lee WS, Hsu C. Sex-specific role of thioredoxin in neuroprotection against iron-induced brain injury conferred by estradiol. Stroke. 2010;41:160–165.
  • Crago EA, Sherwood PR, Bender C, Balzer J, Ren D, Poloyac SM. Plasma estrogen levels are associated with severity of injury and outcomes after aneurysmal subarachnoid hemorrhage. Biol Res Nurs. 2015;17:558–566.
  • Chen Z, Xi G, Mao Y, Keep RF, Hua Y. Effects of progesterone and testosterone on ICH-induced brain injury in rats. Acta Neurochir Suppl. 2011;111:289–293.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.