Individualized spectral filters alleviate persistent photophobia, headaches and migraines in active duty military and Veterans following brain trauma

References

• Agimi Y, Regasa LE, Stout KC. Incidence of traumatic brain injury in the U.S. Military, 2010-2014. Mil Med [ PMID: 30517721]. 2019 May 1;184(5–6):e233–41. doi:10.1093/milmed/usy313.
   PubMed Web of Science ®Google Scholar
• Bruns JJ, Hauser WA. The epidemiology of traumatic brain injury: a review. Epilepsia. 2003 Oct;44(s10):2–10. doi:10.1046/j.1528-1157.44.s10.3.x.
   PubMed Web of Science ®Google Scholar
• Okie S. Traumatic brain injury in the war zone. N Engl J Med. 2005;352(20):2043–2047. doi:10.1056/NEJMp058102.
   PubMed Web of Science ®Google Scholar
• Mares C, Dagher JH, Harissi-Dagher M. Narrative review of the pathophysiology of headaches and photosensitivity in mild traumatic brain injury and concussion. Can J Neurol Sci. 2019 Jan;46(1):14–22. doi:10.1017/cjn.2018.361.
   PubMed Web of Science ®Google Scholar
• Lew HL, Lin PH, Fuh JL, Wang SJ, Clark DJ, Walker WC. Characteristics and treatment of headache after traumatic brain injury: a focused review. Am J Phys Med Rehabil. 2006;85(7):619–627. doi:10.1097/01.phm.0000223235.09931.c0.
   PubMed Web of Science ®Google Scholar
• Hoge CW, McGurk D, Thomas JL, Cox AL, Engel CC, Castro CA. Mild traumatic brain injury in US soldiers returning from Iraq. N Engl J Med. 2008;358(5):453–63. doi:10.1056/NEJMoa072972.
   PubMed Web of Science ®Google Scholar
• Rauchman SH, Albert J, Pinkhasov A, Reiss AB. Mild-to-moderate traumatic brain injury: a review with focus on the Visual System. Neurol Int. 2022 May 30;14(2):453–70. doi:10.3390/neurolint14020038.
   PubMed Web of Science ®Google Scholar
• Armstrong RA. Visual problems associated with traumatic brain injury. Clin Exp Optom. 2018 Nov 1;101(6):716–26. doi:10.1111/cxo.12670.
   PubMed Web of Science ®Google Scholar
• Bansal S, Green K. Application of colored filters in patients post-traumatic brain injury: a review. NeuroRehabilitation. 2022 Jan;1(Preprint):1–0.
   Google Scholar
• Berthold-Lindstedt M, Ygge J, Borg K. Visual dysfunction is underestimated in patients with acquired brain injury. J Rehabil Med. 2017 Apr 1;49(4):327–32. doi:10.2340/16501977-2218.
   PubMed Web of Science ®Google Scholar
• Raucci U, Di Nardo G, Evangelisti M, Villa MP, Parisi P. Photosensitivity in various disease states. In: Trenite DK. The importance of photosensitivity for epilepsy. Springer : Cham (CH); 2021. p.139–50.
   Google Scholar
• Wilkins A, Allen PM, Monger LJ, Gilchrist JM. Visual stress and dyslexia for the practicing optometrist. Optom Pract. 2016;17(2):103–112.
   Google Scholar
• Barbolini G, Lazzerini A, Pini LA, Steiner F, Del Vecchio G, Migaldi M, Cavalllini GM. Malfunctioning cones and remedial tinted filters. Ophta. 2009;2(209):101–05.
   Google Scholar
• Beasley IG, Davies LN. Visual stress symptoms secondary to stroke alleviated with spectral filters and precision tinted ophthalmic lenses: a case report. Clin Exp Optom. 2013;96(1):117–20. doi:10.1111/j.1444-0938.2012.00794.x.
   PubMed Web of Science ®Google Scholar
• Bulmer J Sensory overload and general well-being: Can adults be helped by using Irlen lenses? Unpublished honors thesis, Chester College of Higher Education, Chester, UK. 1994.
   Google Scholar
• Irlen H, Robinson GL. The effect of Irlen coloured filters on adult perception of workplace performance: a preliminary survey. Australian J Remedial Education. 1996;1(3):7–17. doi:10.1080/19404159609546510.
   Google Scholar
• Nobel J, Orton M, Irlen S, Robinson G. A controlled field study of the use of coloured overlays on reading achievement. Australian J Learning Disabilities. 2004;9(2):14–22. doi:10.1080/19404150409546760.
   Google Scholar
• Park SH, Kim S, Cho YA, Joo C. The effect of colored filters in patients with meares-irlen syndrome. J Korean Ophthalmol Soc. 2012;53(3):452–459. doi:10.3341/jkos.2012.53.3.452.
   Google Scholar
• Robinson GL, Foreman PJ. Scotopic sensitivity/Irlen syndrome and the use of coloured filters: a long-term placebo controlled and masked study of reading achievement and perception of ability. Percept Mot Skills. 1999;89(1):83–113. doi:10.2466/pms.1999.89.1.83.
   PubMed Web of Science ®Google Scholar
• Kapoor N, Ciuffreda KJ. Vision disturbances following traumatic brain injury.Curr Treat Options Neurol. 2002;4(4):271–280. doi:10.1007/s11940-002-0027-z.
   PubMedGoogle Scholar
• Wang Y, Wang S, Qiu T, Xiao Z. Photophobia in headache disorders: characteristics and potential mechanisms. J Neurol. 2022;Mar 23:1–13.
   Google Scholar
• Balba NM, McBride AA, Callahan ML, Mist SD, Jones KD, Butler MP, Lim MM, Heinricher MM. Photosensitivity is associated with chronic pain following traumatic brain injury. J Neurotrauma. 2022 May 17;39(17–18):1183–1194. doi:10.1089/neu.2022.0019.
   PubMed Web of Science ®Google Scholar
• Main A, Vlachonikolis I, Dowson A. The wavelength of light causing photophobia in migraine and tension‐type headache between attacks. Headache. 2000 Mar 27;40(3):194–9. doi:10.1046/j.1526-4610.2000.00028.x.
   PubMed Web of Science ®Google Scholar
• Wilkins AJ, Nimmo-Smith I, Slater AI, Bedocs L. Fluorescent lighting, headaches and eyestrain. Light Res Technol. 1989;21(1):11–18. doi:10.1177/096032718902100102.
   Google Scholar
• Noseda R, Bernstein CA, Nir R-R, Lee AJ, Fulton AB, Bertisch SM, Hovaguimian A, Cestari DM, Saavedra-Walker R, Borsook D, et al. Migraine photophobia originating in cone-driven retinal pathways. Brain. 2016;139(7):1971–86. doi:10.1093/brain/aww119.
   PubMedGoogle Scholar
• Stauch BJ, Peter A, Ehrlich I, Nolte Z, Fries P. Human visual gamma for color stimuli. Elife. 2022 May 9;11:e75897. doi:10.7554/eLife.75897.
   PubMed Web of Science ®Google Scholar
• Foster RG. Bright blue times. Nature. 2005 Feb;433(7027):698–9. doi:10.1038/433698a.
   PubMed Web of Science ®Google Scholar
• Elliot AJ, Maier MA. Color psychology: effects of perceiving color on psychological functioning in humans. Ann Rev Psychol. 2014 Jan 1;65(1):95–120. doi:10.1146/annurev-psych-010213-115035.
   PubMedGoogle Scholar
• Mehta R, Zhu R. Blue or red? Exploring the effect of color on cognitive task performances. Sci. 2009 Feb 27;323(5918):1226–9. doi:10.1126/science.1169144.
   PubMed Web of Science ®Google Scholar
• Hu K, De Rosa E, Anderson AK. Differential color tuning of the mesolimbic reward system. Sci Rep. 2020 Jun 23;10(1):1–2. doi:10.1038/s41598-020-66574-w.
   PubMed Web of Science ®Google Scholar
• Noseda R, Copenhagen D, Burstein R. Current understanding of photophobia, visual networks and headaches. Cephalalgia. 2019 Nov;39(13):1623–1634. doi:10.1177/0333102418784750. Epub 2018 Jun 25. PMID: 29940781; PMCID: PMC6461529.
   PubMed Web of Science ®Google Scholar
• Northway N, Manahilov V, Simpson W. Coloured filters improve exclusion of perceptual noise in visually symptomatic dyslexics. J Res Read. 2010 Aug;33(3):223–30. doi:10.1111/j.1467-9817.2009.01409.x.
   Web of Science ®Google Scholar
• Robinson GL, Conway RN. Irlen filters and reading strategies: effect of coloured filters on reading achievement, specific reading strategies, and perception of ability. Percept Mot Skills. 1994 Aug;79(1):467–83. doi:10.2466/pms.1994.79.1.467.
   PubMed Web of Science ®Google Scholar
• Whiting PR, Robinson GL, Parrott CF. Irlen coloured filters for reading: a six year follow-up. Australian J Remedial Education. 1994 Jan;26(3):13–19.
   Google Scholar
• Huang J, Zong X, Wilkins A, Jenkins B, Bozoki A, Cao Y. fMRI evidence that precision ophthalmic tints reduce cortical hyperactivation in migraine. Cephalagia. 2011;31(8):925–36. doi:10.1177/0333102411409076.
   PubMed Web of Science ®Google Scholar
• Chouinard BD, Zhou CI, Hrybouski S, Kim ES, Cummine J. A functional neuroimaging case study of Meares-Irlen syndrome/visual stress (MISViS). Brain Topogr. 2012;25(3):293–307. doi:10.1007/s10548-011-0212-z.
   PubMed Web of Science ®Google Scholar
• Lewine JD, Irlen HL, Orrison WW Visual evoked magnetic fields in scotopic sensitivity syndrome. 1996. Report available from New Mexico Institute of Neuroimaging. The New Mexico Regional Field Medical Center: Albuquerque, NM.
   Google Scholar
• Riddell PM, Wilkins A, Hainline L. The effect of colored lenses on the visual evoked response in children with visual stress. Optom Vis Sci. 2006;83(5):299–305. doi:10.1097/01.opx.0000216125.83236.af.
   PubMed Web of Science ®Google Scholar
• Wilkins A, Sihra N, Smith IN. How precise do precision tints have to be and how many are necessary? Ophthalmic Physiol Opt. 2005;25(3):269–76. doi:10.1111/j.1475-1313.2005.00279.x.
   PubMed Web of Science ®Google Scholar
• Fimreite V, Willeford KT, Ciuffreda KJ. Effect of chromatic filters on visual performance in individuals with mild traumatic brain injury (mTBI): a pilot study. J Optom. 2016 Oct 1;9(4):231–9. doi:10.1016/j.optom.2016.04.004.
   PubMedGoogle Scholar
• Clark J, Hasselfeld K, Bigsby K, Divine J. Colored glasses to mitigate photophobia symptoms posttraumatic brain injury. J Athl Train. 2017 Aug;52(8):725–9. doi:10.4085/1062-6050-52.4.04.
   PubMed Web of Science ®Google Scholar
• Jackowski MM, Sturr JF, Taub HA, Turk MA. Photophobia in patients with traumatic brain injury: uses of light-filtering lenses to enhance contrast sensitivity and reading rate. Neurorehabilitation. 1996 Jan 1;6(3):193–201. doi:10.3233/NRE-1996-6305.
   PubMed Web of Science ®Google Scholar
• Stern CD. Photophobia, light, and color in acquired brain injury. In: Sutter PS, Harvey LH. Vision Rehabilitation. New York (NY): Routledge; 2011. p. 283–300.
   Google Scholar
• Ahmad MT, Singman EL. Photophobia in post-concussive syndrome. In: Henderson AD, Carey AR. Controversies in neuro-ophthalmic management. Springer : Cham (CH); 2021. p. 235–42.
   Google Scholar
• Gubata ME, Packnett ER, Blandford CD, Piccirillo AL, Niebuhr DW, Cowan DN. Trends in the epidemiology of disability related to traumatic brain injury in the US Army and Marine Corps: 2005 to 2010. J Head Trauma Rehabil. 2014;29(1):65–75. doi:10.1097/HTR.0b013e318295f590.
   PubMed Web of Science ®Google Scholar
• Heltemes KJ, Holbrook TL, Macgregor AJ, Galarneau MR. Blast-related mild traumatic brain injury is associated with a decline in self-rated health amongst US military personnel. Injury. 2012;43(12):1990–95. doi:10.1016/j.injury.2011.07.021.
   PubMed Web of Science ®Google Scholar
• Ahrens A, Finkel A. Persistent post traumatic headache. Brain Injury Professional. 2022;19(1):14.
   Google Scholar
• Irlen H. Irlen reading perceptual scale (IRPS). Long Beach (CA): Perceptual Development Corporation; 2018.
   Google Scholar
• Irlen H. Irlen method clinical handbook. Long Beach (CA): Perceptual Development Corporation; 1988.
   Google Scholar
• Jeanes R, Busby A, Martin J, Lewis E, Stevenson N, Pointon D, Wilkins A. Prolonged use of coloured overlays for classroom reading. Brit J Psychol. 1997 Nov;88(4):541–48. doi:10.1111/j.2044-8295.1997.tb02656.x.
   Google Scholar
• Wilkins A, Lewis E, Smith F, Rowland E, Tweedie W. Coloured overlays and their benefit for reading. J Res Read. 2001 Feb;24(1):41–64. doi:10.1111/1467-9817.00132.
   Google Scholar
• Yang M, Rendas-Baum R, Varon SF, Kosinski M. Validation of the headache impact test (HIT-6™) across episodic and chronic migraine. Cephalalgia. 2011;31(3):357–367. doi:10.1177/0333102410379890.
   PubMed Web of Science ®Google Scholar
• Houts CR, Wirth RJ, McGinley JS, Gwaltney C, Kassel E, Snapinn S, Cady R. Content validity of HIT‐6 as a measure of headache impact in people with migraine: a narrative review. Headache. 2020 Jan;60(1):28–39. doi:10.1111/head.13701.
   PubMed Web of Science ®Google Scholar
• Bouldoukian J, Wilkins AJ, Evans BJ. Randomised controlled trial of the effect of coloured overlays on the rate of reading of people with specific learning difficulties. Ophthal Physl Opt. 2002 Jan 9;22(1):55–60. doi:10.1046/j.1475-1313.2002.00002.x.
   PubMed Web of Science ®Google Scholar
• Whiting PR, Robinson GL. Using Irlen coloured lenses for reading: a clinical study. Educ Dev Phychol. 1988 Nov;5(2):7–10. doi:10.1017/S0816512200025888.
   Google Scholar
• Wilkins AJ, Evans BJ, Brown JA, Busby AE, Wingfield AE, Jeanes RJ, Bald J. Double‐masked placebo‐controlled trial of precision spectral filters in children who use coloured overlays. Ophthal Physl Opt. 1994 Oct;14(4):365–70. doi:10.1111/j.1475-1313.1994.tb00126.x.
   PubMed Web of Science ®Google Scholar
• Guimarães MR, Vilhena DD, Loew SJ, Guimarães RQ. Spectral overlays for reading difficulties: oculomotor function and reading efficiency among children and adolescents with visual stress. Percept Mot Skills. 2020 Apr;127(2):490–509. doi:10.1177/0031512519889772.
   PubMed Web of Science ®Google Scholar
• Kim JH, Seo HJ, Ha SG, Kim SH. Functional magnetic resonance imaging findings in Meares-Irlen syndrome: a Pilot sudy. Korean J Ophthalmol. 2015 Apr 1;29(2):121–25. doi:10.3341/kjo.2015.29.2.121.
   PubMedGoogle Scholar
• Wedekind C, Lippert-Grüner M. Long-term outcome in severe traumatic brain injury is significantly influenced by brainstem involvement. Brain Inj. 2005 Aug 20;19(9):681–4. doi:10.1080/02699050400025182.
   PubMed Web of Science ®Google Scholar
• Lubejko S, Livrizzi G, Banghart MR. Investigating the role of the locus coeruleus in Periaqueductal Gray-mediated Antinociception. J Pain. 2022;23(5):24. doi:10.1016/j.jpain.2022.03.093.
   Web of Science ®Google Scholar
• Gross J, Schnitzler A, Timmermann L, Ploner M, Fries P. Gamma oscillations in human primary somatosensory cortex reflect pain perception. PLoS Biol. 2007 May;5(5):e133. doi:10.1371/journal.pbio.0050133. PMID: 17456008; PMCID: PMC1854914.
   PubMed Web of Science ®Google Scholar
• Martenson ME, Halawa OI, Tonsfeldt KJ, Maxwell CA, Hammack N, Mist SD, Pennesi ME, Bennett RM, Mauer KM, Jones KD, et al. A possible neural mechanism for photosensitivity in chronic pain. Pain. 2016 Apr;157(4):868–878. doi:10.1097/j.pain.0000000000000450. PMID: 26785323; PMCID: PMC4794405.
   PubMed Web of Science ®Google Scholar
• Hoggan RN, Subhash A, Blair S, Digre KB, Baggaley SK, Gordon J, Brennan KC, Warner JE, Crum AV, Katz BJ. Thin-film optical notch filter spectacle coatings for the treatment of migraine and photophobia. J Clin Neurosci. 2016 Jun 1;28:71–76. doi:10.1016/j.jocn.2015.09.024.
   PubMed Web of Science ®Google Scholar