Discrimination between safe and unsafe stimuli mediates the relationship between trait anxiety and return of fear

References

• Barry, T. J., Vervliet, B., & Hermans, D. (2016). Threat-related gaze fixation and its relationship with the speed and generalisability of extinction learning. Australian Journal of Psychology, 68(3), 200–208. doi: 10.1111/ajpy.12124
   Web of Science ®Google Scholar
• Boddez, Y., Baeyens, F., Luyten, L., Vansteenwegen, D., Hermans, D., & Beckers, T. (2013). Rating data are underrated: Validity of US expectancy in human fear conditioning. Journal of Behavior Therapy and Experimental Psychiatry, 44, 201–206. doi: 10.1016/j.jbtep.2012.08.003
   PubMed Web of Science ®Google Scholar
• Bouton, M. E. (1993). Context, time, and memory retrieval in the interference paradigms of pavlovian learning. Psychological Bulletin, 114(1), 80–99. doi: 10.1037/0033-2909.114.1.80
   PubMed Web of Science ®Google Scholar
• Carver, C. S., & White, T. L. (1994). Behavioral inhibition, behavioral activation, and affective responses to impending reward and punishment: The BIS/BAS scales. Journal of Personality and Social Psychology, 105, 637–647. doi: 10.1037/0022-3514.67.2.319
   Web of Science ®Google Scholar
• Duits, P., Cath, D. C., Lissek, S., Hox, J. J., Hamm, A. O., Engelhard, I. M., … Baas, J. M. P. (2015). Updated meta-analysis of classical fear conditioning in the anxiety disorders. Depression and Anxiety, 32, 239–253. doi: 10.1002/da.22353
   PubMed Web of Science ®Google Scholar
• Eysenck, M. W. (2010). Attentional control theory of anxiety: Recent developments. In Handbook of individual differences in cognition: Attention, memory, and executive control (pp. 195–204). New York, NY: Springer Science + Business Media. doi: 10.1007/978-1-4419-1210-7_12
   Google Scholar
• Grillon, C. (2002). Associative learning deficits increase symptoms of anxiety in humans. Biological Psychiatry, 51, 851–858. doi: 10.1016/s0006-3223(01)01370-1
   PubMed Web of Science ®Google Scholar
• Haaker, J., Lonsdorf, T. B., Schümann, D., Menz, M., Brassen, S., Bunzeck, N., … Kalisch, R. (2015). Deficient inhibitory processing in trait anxiety: Evidence from context-dependent fear learning, extinction recall and renewal. Biological Psyciatry, 111, 65–72. doi: 10.1016/j.biopsycho.2015.07.010
   PubMed Web of Science ®Google Scholar
• Hayes, A. F. (2009). Beyond Baron and Kenny: Statistical mediation analysis in the new millennium. Communication Monographs, 76(4), 408–420. doi: 10.1080/03637750903310360
   Web of Science ®Google Scholar
• Hayes, A. F. (2012). PROCESS: A versatile computational tool for observed variable mediation, moderation, and conditional process modeling [White paper]. Retrieved from http://www.afhayes.com/ public/process2012.pdf
   Google Scholar
• Hermann, A., Stark, R., Milad, M. R., & Merz, C. J. (2016). Renewal of conditioned fear in a novel context is associated with hippocampal activation and connectivity. Social Cognitive and Affective Neuroscience. Advance Online Publication. doi: 10.1093/scan/nsw047
   PubMed Web of Science ®Google Scholar
• Indovina, I., Robbins, T. W., Núñez-Elizalde, A. O., Dunn, B. D., & Bishop, S. J. (2011). Fear-conditioning mechanisms associated with trait vulnerability to anxiety in humans. Neuron, 69(3), 563–571. doi: 10.1016/j.neuron.2010.12.034
   PubMed Web of Science ®Google Scholar
• Joos, E., Vansteenwegen, D., & Hermans, D. (2012). Post-acquisition repetitive though in fear conditioning: An experimental investigation of the effect of CS-US-rehearsal. Journal of Behavioral Therapy and Experimental Psychiatry, 43, 737–744. doi: 10.1016/j.jbtep.2011.10.011
   PubMed Web of Science ®Google Scholar
• Jovanovic, T., Ely, T., Fani, N., Glover, E. M., Gutman, D., Tone, E. B., … Ressler, K. J. (2013). Reduced neural activation during an inhibition task is associated with impaired fear inhibition in a traumatized civilian sample. Cortex, 49, 1884–1891. doi: 10.1016/j.cortex.2012.08.011
   Google Scholar
• Lissek, S., Kaczkurkin, A. N., Rabin, S., Geraci, M., Pine, D. S., & Grillon, C. (2014). Generalized anxiety disorder is associated with overgeneralization of classically conditioned fear. Biological Psychiatry, 75(11), 909–915. doi: 10.1016/j.biopsych.2013.07.025
   PubMed Web of Science ®Google Scholar
• MacKinnon, D. P., & Fairchild, A. J. (2009). Current directions in mediation analysis. Current Directions in Psychological Science, 18(1), 16–20. doi: 10.1111/j.1467-8721.2009.01598.x
   PubMed Web of Science ®Google Scholar
• MacKinnon, D. P., Fairchild, A. J., & Fritz, M. S. (2007). Mediation analysis. Annual Review of Psychology, 58, 593–614. doi: 10.1146/annurev.psych.58.110405.085542
   PubMed Web of Science ®Google Scholar
• Milad, M. R., Pitman, R. K., Ellis, C. B., Gold, A. L., Shin, L. M., Lasko, N. B., … Rauch, S. L. (2009). Neurobiological basis of failure to recall extinction memory in posttraumatic stress disorder. Biological Psychiatry, 66, 1075–1082. doi: 10.1016/j.biopsych.2009.06.026
   PubMed Web of Science ®Google Scholar
• Prenoveau, J. M., Craske, M. G., Liao, B., & Ornitz, E. M. (2011). Associative conditioning deficits: Caused by or cause of anxiety? Journal of Experimental Psychopathology, 2(3), 432–448. doi: 10.5127/jep.018211
   Google Scholar
• Psychology Software Tools, Inc. [E-Prime 2.0]. (2012). Retrieved from http://www.pstnet.com
   Google Scholar
• Quirk, G. (2002). Memory for extinction of conditioned fear is long-lasting and persists following spontaneous recovery. Learning and Memory, 9, 402–407. doi: 10.1101/lm.49602
   PubMed Web of Science ®Google Scholar
• Sehlmeyer, C., Dannlowski, U., Schöning, S., Kugel, H., Pyka, M., Pfleiderer, B., … Konrad, C. (2011). Neural correlates of trait anxiety in fear extinction. Psychological Medicine, 41(4), 789–798. doi: 10.1017/S0033291710001248
   PubMed Web of Science ®Google Scholar
• Tottenham, N., Tanaka, J. W., Leon, A. C., McCarry, T., Nurse, M., Hare, T. A., … Nelson, C. (2009). The NimStim set of facial expressions: Judgments from untrained research participants. Psychiatry Research, 168(3), 242–249. doi: 10.1016/j.psychres.2008.05.006
   PubMed Web of Science ®Google Scholar
• Vervliet, B., Craske, M. G., & Hermans, D. (2013). Fear extinction and relapse: State of the art. Annual Review of Clinical Psychology, 9, 215–248. doi: 10.1146/annurev-clinpsy-050212-185542
   PubMed Web of Science ®Google Scholar
• Zhao, X., Lynch, J. G., & Chen, Q. (2010). Reconsidering Baron and Kenny: Myths and truths about mediation analysis. Journal of Consumer Research, 37(2), 197–206. doi: 10.1086/651257
   Web of Science ®Google Scholar