148
Views
0
CrossRef citations to date
0
Altmetric
Articles

L-arginine Improves Plasma Lipid Profile and Muscle Inflammatory Response in Trained Rats After High-Intense Exercise

Pages 82-90 | Received 14 Feb 2019, Accepted 23 Dec 2019, Published online: 28 Feb 2020

References

  • Alvarez, L. C., Ramirez-Campillo, R., Flores, O. M., Henriquez-Olguin, C., Campos, J. C., Carrasco, V., … Celis-Morales, C. (2013). Metabolic response to high intensity exercise training in sedentary hyperglycemic and hypercholesterolemic women. Revista Medica De Chile, 141(10), 1293–1299. doi:10.4067/S0034-98872013001000008
  • Amano, H., Oishi, K., Sonoda, F., Senba, M., Wada, A., Nakagawa, H., & Nagatake, T. (2000). Role of cytokine-induced neutrophil chemoattractant-2 (CINC-2) alpha in a rat model of chronic bronchopulmonary infections with Pseudomonas aeruginosa. Cytokine, 12(11), 1662–1668. doi:10.1006/cyto.2000.0771
  • Awobajo, F. O., Olawale, O. A., & Bassey, S. (2013). Changes in blood glucose, lipid profile and antioxidant activities in trained and untrained adult male subjects during programmed exercise on the treadmill. Nigerian Quarterly Journal of Hospital Medicine, 23(2), 117–124.
  • Balkowiec-Iskra, E. (2010). The role of immune system in inflammatory pain pathophysiology. Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego, 29(174), 395–399.
  • Baumert, P., Lake, M. J., Stewart, C. E., Drust, B., & Erskine, R. M. (2016). Genetic variation and exercise-induced muscle damage: Implications for athletic performance, injury and ageing. European Journal of Applied Physiology, 116(9), 1595–1625. doi:10.1007/s00421-016-3411-1
  • Bogdanski, P., Suliburska, J., Szulinska, M., Sikora, M., Walkowiak, J., & Jakubowski, H. (2015). L-arginine and vitamin C attenuate pro-atherogenic effects of high-fat diet on biomarkers of endothelial dysfunction in rats. Biomedicine & Pharmacotherapy, 76, 100–106. doi:10.1016/j.biopha.2015.10.001
  • Borges Lda, S., Dermargos, A., da Silva, E. P., Junior, Weimann, E., Lambertucci, R. H., & Hatanaka, E. (2015). Melatonin decreases muscular oxidative stress and inflammation induced by strenuous exercise and stimulates growth factor synthesis. Journal of Pineal Research, 58(2), 166–172. doi:10.1111/jpi.12202
  • Bradford, M. M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry, 72, 248–254. doi:10.1016/0003-2697(76)90527-3
  • Chazaud, B. (2016). Inflammation during skeletal muscle regeneration and tissue remodeling: Application to exercise-induced muscle damage management. Immunology and Cell Biology, 94(2), 140–145. doi:10.1038/icb.2015.97
  • Cruzat, V. F., Krause, M., & Newsholme, P. (2014). Amino acid supplementation and impact on immune function in the context of exercise. Journal of the International Society of Sports Nutrition, 11(1), 61. doi:10.1186/s12970-014-0061-8
  • Cui, H. X., Yang, S. Y., Wang, H. Y., Zhao, J. P., Jiang, R. R., Zhao, G. P., … Wen, J. (2010). The effect of a mutation in the 3-UTR region of the HMGCR gene on cholesterol in Beijing-you chickens. Animal Biotechnology, 21(4), 241–251. doi:10.1080/10495398.2010.514777
  • Dashtabi, A., Mazloom, Z., Fararouei, M., & Hejazi, N. (2016). Oral L-arginine administration improves anthropometric and biochemical indices associated with cardiovascular diseases in obese patients: A randomized, single blind placebo controlled clinical trial. Research in Cardiovascular Medicine, 5(1), e29419. doi:10.5812/cardiovascmed.29419
  • Dor-Haim, H., Berenfeld, O., Horowitz, M., Lotan, C., & Swissa, M. (2013). Reduced ventricular arrhythmogeneity and increased electrical complexity in normal exercised rats. PLoS One, 8(6), e66658. doi:10.1371/journal.pone.0066658
  • Escudero, A., Petzold, G., Moreno, J., Gonzalez, M., Junod, J., Aguayo, C., … Escudero, C. (2013). Supplementation with apple enriched with L-arginine may improve metabolic control and survival rate in alloxan-induced diabetic rats. Biofactors, 39(5), 564–574. doi:10.1002/biof.1103
  • Ferraro, E., Giammarioli, A. M., Chiandotto, S., Spoletini, I., & Rosano, G. (2014). Exercise-induced skeletal muscle remodeling and metabolic adaptation: Redox signaling and role of autophagy. Antioxidants & Redox Signaling, 21(1), 154–176. doi:10.1089/ars.2013.5773
  • Foger, B., Wohlfarter, T., Ritsch, A., Lechleitner, M., Miller, C. H., Dienstl, A., & Patsch, J. R. (1994). Kinetics of lipids, apolipoproteins, and cholesteryl ester transfer protein in plasma after a bicycle marathon. Metabolism, 43(5), 633–639. doi:10.1016/0026-0495(94)90207-0
  • Fouad, A. M., El-Senousey, H. K., Yang, X. J., & Yao, J. H. (2013). Dietary L-arginine supplementation reduces abdominal fat content by modulating lipid metabolism in broiler chickens. Animal, 7(8), 1239–1245. doi:10.1017/S1751731113000347
  • Gleeson, M. (2000). Interleukins and exercise. The Journal of Physiology, 529(Pt 1), 1. doi:10.1111/tjp.2000.529.issue-1
  • Graham, T. E. (2004). Exercise, postprandial triacylglyceridemia, and cardiovascular disease risk. Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquee, 29(6), 781–799. doi:10.1139/h04-051
  • Hernandez, A., Cheng, A., & Westerblad, H. (2012). Antioxidants and skeletal muscle performance: “Common knowledge” vs. experimental evidence. Frontiers in Physiology, 3, 46. doi:10.3389/fphys.2012.00046
  • Huang, C. C., Tsai, S. C., & Lin, W. T. (2008). Potential ergogenic effects of L-arginine against oxidative and inflammatory stress induced by acute exercise in aging rats. Experimental Gerontology, 43(6), 571–577. doi:10.1016/j.exger.2008.03.002
  • Keller, C., Steensberg, A., Hansen, A. K., Fischer, C. P., Plomgaard, P., & Pedersen, B. K. (2005). Effect of exercise, training, and glycogen availability on IL-6 receptor expression in human skeletal muscle. Journal of Applied Physiology, 99(6), 2075–2079. doi:10.1152/japplphysiol.00590.2005
  • Kohli, R., Meininger, C. J., Haynes, T. E., Yan, W., Self, J. T., & Wu, G. (2004). Dietary L-arginine supplementation enhances endothelial nitric oxide synthesis in streptozotocin-induced diabetic rats. The Journal of Nutrition, 134(3), 600–608. doi:10.1093/jn/134.3.600
  • Kohorst, M. A., Warad, D. M., Rao, A. A. N., & Rodriguez, V. (2018). Obesity, sedentary lifestyle, and video games: The new thrombophilia cocktail in adolescents. Pediatric Blood & Cancer, 65(7), e27041. doi:10.1002/pbc.27041
  • Leowattana, W. (2018). Obesity and acute cardiovascular events. European Journal of Preventive Cardiology, 25(6), 618–620. doi:10.1177/2047487318758361
  • Maxwell, A. J., Ho, H. V., Le, C. Q., Lin, P. S., Bernstein, D., & Cooke, J. P. (2001). L-arginine enhances aerobic exercise capacity in association with augmented nitric oxide production. Journal of Applied Physiology, 90(3), 933–938. doi:10.1152/jappl.2001.90.3.933
  • McKnight, J. R., Satterfield, M. C., Jobgen, W. S., Smith, S. B., Spencer, T. E., Meininger, C. J., … Wu, G. (2010). Beneficial effects of L-arginine on reducing obesity: Potential mechanisms and important implications for human health. Amino Acids, 39(2), 349–357. doi:10.1007/s00726-010-0598-z
  • Morais, S. R. L., Brito, V. G. B., Mello, W. G., & Oliveira, S. H. P. (2018). l-arginine modulates inflammation and muscle regulatory genes after a single session of resistance exercise in rats. Scandinavian Journal of Medicine & Science in Sports, 28(2), 425–435. doi:10.1111/sms.12935
  • Pahlavani, N., Jafari, M., Sadeghi, O., Rezaei, M., Rasad, H., Rahdar, H. A., & Entezari, M. H. (2014). L-arginine supplementation and risk factors of cardiovascular diseases in healthy men: A double-blind randomized clinical trial. F1000Res, 3, 306. doi:10.12688/f1000research.5877.2
  • Pedersen, B. K., & Febbraio, M. A. (2008). Muscle as an endocrine organ: Focus on muscle-derived interleukin-6. Physiological Reviews, 88(4), 1379–1406. doi:10.1152/physrev.90100.2007
  • Rajapakse, N. W., & Mattson, D. L. (2009). Role of L-arginine in nitric oxide production in health and hypertension. Clinical and Experimental Pharmacology and Physiology, 36(3), 249–255. doi:10.1111/j.1440-1681.2008.05123.x
  • Ring-Dimitriou, S., von Duvillard, S. P., Paulweber, B., Stadlmann, M., Lemura, L. M., Peak, K., & Mueller, E. (2007). Nine months aerobic fitness induced changes on blood lipids and lipoproteins in untrained subjects versus controls. European Journal of Applied Physiology, 99(3), 291–299. doi:10.1007/s00421-006-0347-x
  • Rondon, E., Brasileiro-Santos, M. S., Moreira, E. D., Rondon, M. U., Mattos, K. C., Coelho, M. A., … Negrao, C. E. (2006). Exercise training improves aortic depressor nerve sensitivity in rats with ischemia-induced heart failure. American Journal of Physiology-Heart and Circulatory Physiology, 291(6), H2801–H2806. doi:10.1152/ajpheart.01352.2005
  • Ryu, S., Kim, H., Mun, J., Kang, M., & Jang, Y. (2018). Association between sedentary behavior and obesity in adolescents. Research Quarterly for Exercise and Sport, 89, A33–A34.
  • Schaefer, A., Piquard, F., Geny, B., Doutreleau, S., Lampert, E., Mettauer, B., & Lonsdorfer, J. (2002). L-arginine reduces exercise-induced increase in plasma lactate and ammonia. International Journal of Sports Medicine, 23(6), 403–407. doi:10.1055/s-2002-33743
  • Sene-Fiorese, M., Duarte, F. O., Scarmagnani, F. R., Cheik, N. C., Manzoni, M. S., Nonaka, K. O., … Damaso, A. R. (2008). Efficiency of intermittent exercise on adiposity and fatty liver in rats fed with high-fat diet. Obesity (Silver Spring), 16(10), 2217–2222. doi:10.1038/oby.2008.339
  • Shan, X., Zhou, J., Ma, T., & Chai, Q. (2011). Lycium barbarum polysaccharides reduce exercise-induced oxidative stress. International Journal of Molecular Sciences, 12(2), 1081–1088. doi:10.3390/ijms12021081
  • Shi, F. K., & Miao, R. F. (2017). Study of cytokine as a predictor of antidepressant effects of physical exercise in depression. International Journal of Clinical and Experimental Medicine, 10(2), 2217–2223.
  • Silva, E. P., Jr., Borges, L. S., Mendes-da-Silva, C., Hirabara, S. M., & Lambertucci, R. H. (2017). l-arginine supplementation improves rats’ antioxidant system and exercise performance. Free Radical Research, 51(3), 281–293. doi:10.1080/10715762.2017.1301664
  • Skinner, E. R., Black, D., & Maughan, R. J. (1985). Variability in the response of different male subjects to the effect of marathon running on the increase in plasma high density lipoprotein. European Journal of Applied Physiology and Occupational Physiology, 54(5), 488–493. doi:10.1007/BF00422957
  • Suliburska, J., Bogdanski, P., Krejpcio, Z., Pupek-Musialik, D., & Jablecka, A. (2014). The effects of L-arginine, alone and combined with vitamin C, on mineral status in relation to its antidiabetic, anti-inflammatory, and antioxidant properties in male rats on a high-fat diet. Biological Trace Element Research, 157(1), 67–74. doi:10.1007/s12011-013-9867-5
  • Suzuki, K., Nakaji, S., Yamada, M., Totsuka, M., Sato, K., & Sugawara, K. (2002). Systemic inflammatory response to exhaustive exercise. Cytokine kinetics. Exercise Immunology Review, 8, 6–48.
  • Taboada, M. C., Rodriguez, B., Millan, R., & Miguez, I. (2006). Role of dietary l-arginine supplementation on serum parameters and intestinal enzyme activities in rats fed an excess-fat diet. Biomedicine & Pharmacotherapy, 60(1), 10–13. doi:10.1016/j.biopha.2005.07.014
  • Tripathi, P., Chandra, M., & Misra, M. K. (2009). Oral administration of L-arginine in patients with angina or following myocardial infarction may be protective by increasing plasma superoxide dismutase and total thiols with reduction in serum cholesterol and xanthine oxidase. Oxidative Medicine and Cellular Longevity, 2(4), 231–237. doi:10.4161/oxim.2.4.9233
  • Vaisberg, M., Bachi, A. L., Latrilha, C., Dioguardi, G. S., Bydlowski, S. P., & Maranhao, R. C. (2012). Lipid transfer to HDL is higher in marathon runners than in sedentary subjects, but is acutely inhibited during the run. Lipids, 47(7), 679–686. doi:10.1007/s11745-012-3685-y
  • Vinagre, C. G., Ficker, E. S., Finazzo, C., Alves, M. J., de Angelis, K., Irigoyen, M. C., … Maranhao, R. C. (2007). Enhanced removal from the plasma of LDL-like nanoemulsion cholesteryl ester in trained men compared with sedentary healthy men. Journal of Applied Physiology, 103(4), 1166–1171. doi:10.1152/japplphysiol.01176.2006
  • Wax, B., Kavazis, A. N., Webb, H. E., & Brown, S. P. (2012). Acute L-arginine alpha ketoglutarate supplementation fails to improve muscular performance in resistance trained and untrained men. Journal of the International Society of Sports Nutrition, 9(1), 17. doi:10.1186/1550-2783-9-17
  • Wu, H., & Ballantyne, C. M. (2017). Skeletal muscle inflammation and insulin resistance in obesity. Journal of Clinical Investigation, 127(1), 43–54. doi:10.1172/JCI88880
  • Wu, H. J., Chen, K. T., Shee, B. W., Chang, H. C., Huang, Y. J., & Yang, R. S. (2004). Effects of 24 h ultra-marathon on biochemical and hematological parameters. World Journal of Gastroenterology, 10(18), 2711–2714. doi:10.3748/wjg.v10.i18.2711
  • Wu, Z., Hou, Y., Hu, S., Bazer, F. W., Meininger, C. J., McNeal, C. J., & Wu, G. (2016). Catabolism and safety of supplemental L-arginine in animals. Amino Acids, 48(7), 1541–1552. doi:10.1007/s00726-016-2245-9

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.