REFERENCES
- Kino T, Hatanaka H, Hashimoto M, Nishiyama M, Goto T, Okuhara M, Kohsaka M, Aoki H, Imanaka H. FK-506, A novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics. J Antibiot (Tokyo). 1987; 40: 1249–1255, [CSA]
- Sawada S, Suzuki G, Kawase Y, Takaku F. Novel immunosuppressive agent, FK506. In vitro effects on the cloned T cell activation. J Immunol. 1987; 139: 1797–1803, [PUBMED], [INFOTRIEVE]
- Starzl T E, Todo S, Fung J, Demetris A J, Venkataramman R, Jain A. FK 506 for liver, kidney, and pancreas transplantation. Lancet. 1989; 2(8670)1000–1004, [PUBMED], [INFOTRIEVE]
- Kawashima H, Fujino Y, Mochizuki M. Effects of a new immunosuppressive agent, FK506, on experimental autoimmune uveoretinitis in rats. Invest Ophthalmol Vis Sci. 1988; 29: 1265–1271, [PUBMED], [INFOTRIEVE]
- Mochizuki M, Ikeda E, Shirao M, Fujito S, Yoshimura K, Shimada N. Preclinical and clinical study of FK506 in uveitis. Curr Eye Res. 1992; 11(Suppl)87–95, [PUBMED], [INFOTRIEVE]
- Mochizuki M, Masuda K, Sakane T, Inaba G, Ito K, Kogure M, Sugino N, Usui M, Mizushima Y, Ohno S, Miyanaga Y, Hayasaka S, Ohizumi K. A multicenter clinical open trial of FK 506 in refractory uveitis, including Behcet's disease. Japanese FK 506 Study Group on Refractory Uveitis. Transplant Proc. 1991; 23: 3343–3346, [PUBMED], [INFOTRIEVE]
- Sloper C M, Powell R J, Dua H S. Tacrolimus (FK506) in the treatment of posterior uveitis refractory to cyclosporine. Ophthalmology. 1999; 106: 723–728, [PUBMED], [INFOTRIEVE], [CSA]
- Rikkers S M, Holland G N, Drayton G E, Michel F K, Torres M F, Takahashi S. Topical tacrolimus treatment of atopic eyelid disease. Am J Ophthalmol. 2003; 135: 297–302, [PUBMED], [INFOTRIEVE], [CSA]
- Sharkey J, Butcher S P. Immunophilins mediate the neuroprotective effects ofFK506 in focal cerebral ischaemia. Nature. 1994; 371: 336–339, [PUBMED], [INFOTRIEVE]
- Dawson T M, Steiner J P, Dawson V L, Dinerman J L, Uhl G R, Snyder S H. Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity. Proc Natl Acad Sci U S A. 1993; 90: 9808–9812, [PUBMED], [INFOTRIEVE], [CSA]
- Tsujikawa A, Ogura Y, Hiroshiba N, Miyamoto K, Kiryu J, Honda Y. Tacrolimus(FK506) attenuates leukocyte accumulation after transient retinalischemia. Stroke. 1998; 29: 1431–1438, [PUBMED], [INFOTRIEVE], [CSA]
- Wang H G, Pathan N, Ethell I M, Krajewski S, Yamaguchi Y, Shibasaki F, Mc Keon F, Bobo T, Franke T F, Reed J C. Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD. Science 1999; 284: 339–343, [PUBMED], [INFOTRIEVE]
- Uchino H, Minamikawa-Tachino R, Kristian T, Perkins G, Narazaki M, Siesjo B K, Shibasaki F. Differential neuroprotection by cyclosporin A and FK506 following ischemia corresponds with differing abilities to inhibit calcineurin and the mitochondrial permeability transition. Neurobiol Dis. 2002; 10: 219–233, [PUBMED], [INFOTRIEVE], [CSA]
- Furuichi Y, Katsuta K, Maeda M, Ueyama N, Moriguchi A, Matsuoka N, Goto T, Yanagihara T. Neuroprotective action of tacrolimus (FK506) in focal and global cerebral ischemia in rodents: Dose dependency, therapeutic time window and long-term efficacy. Brain Res. 2003; 965: 137–145, [PUBMED], [INFOTRIEVE]
- Freeman E E, Grosskreutz C L. The effects of FK506 on retinal ganglion cells after optic nerve crush. Invest Ophthalmol Vis Sci. 2000; 41: 1111–1115, [PUBMED], [INFOTRIEVE], [CSA]
- Kikuchi M, Kashii S, Mandai M, Yasuyoshi H, Honda Y, Kaneda K, Akaike A. Protective effects of FK506 against glutamate-induced neurotoxicity in retinal cell culture. Invest Ophthalmol Vis Sci. 1998; 39: 1227–1232, [PUBMED], [INFOTRIEVE], [CSA]
- Lightman S, Chan C C. Immune mechanisms in choroido-retinal inflammation in man. Eye 1990; 4: 345–353, [PUBMED], [INFOTRIEVE]
- Hikita N, Chan C C, Whitcup S M, Nussenblatt R B, Mochizuki M. Effects of topical FK506 on endotoxin-induced uveitis (EIU) in the Lewis rat. Curr Eye Res. 1995; 14: 209–214, [PUBMED], [INFOTRIEVE]
- Jaffe G J, Ben-Nun J, Guo H, Dunn J P, Ashton P. Fluocinolone acetonide sustained drug delivery device to treat severe uveitis. Ophthalmology. 2000; 107: 2024–2033, [PUBMED], [INFOTRIEVE], [CSA]
- Young S, Larkin G, Branley M, Lightman S. Safety and efficacy of intravitreal triamcinolone for cystoid macular oedema in uveitis. Clin Exp Ophthalmol. 2001; 29: 2–6, [CSA]
- Tamura K, Kobayashi M, Hashimoto K, Kojima K, Nagase K, Iwasaki K, Kaizu T, Tanaka H, Niwa M. A highly sensitive method to assay FK-506 levels in plasma. Transplant Proc. 1987; 19((5 Suppl 6))23–29, [PUBMED], [INFOTRIEVE]
- Hall J M, O'Connor G R. Correlation between ocular inflammation and antibody production. I. Serum antibody response following intravitreal immunization with protein antigens. J Immunol. 1970; 104: 432–439, [PUBMED], [INFOTRIEVE]
- Hogan M J, Kimura S M, Thygeson P. Signs and symptoms of uveitis. I. AnteriorUveitis. Am J Ophthalmol. 1959; 47: 171–180, [PUBMED], [INFOTRIEVE]
- Jaffe G J, Yang C S, Wang X C, Cousins S W, Gallemore R P, Ashton P. Intravitreal sustained-release cyclosporine in the treatment of experimental uveitis. Ophthalmology. 1998; 105: 46–56, [PUBMED], [INFOTRIEVE], [CSA]
- Caspi R R, Chan C C, Fujino Y, Najafian F, Grover S, Hansen C T, Wilder R L. Recruitment of antigen-nonspecific cells plays a pivotal role in the pathogenesis of a T cell-mediated organ-specific autoimmune disease, experimental autoimmune uveoretinitis. J Neuroimmunol. 1993; 47: 177–188, [PUBMED], [INFOTRIEVE]
- Sartani G, Silver P B, Strassmann G, Chan C C, Caspi R R. Suramin treatment suppresses induction of experimental autoimmune uveoretinitis (EAU) in rodents. Curr Eye Res. 1995; 14: 887–896, [PUBMED], [INFOTRIEVE]
- Hughes W F. Quantitation of ischemic damage in the rat retina. Exp Eye Res. 1991; 53: 573–582, [PUBMED], [INFOTRIEVE], [CSA]
- Passos E, Genaidy M M, Peyman G A. Ocular toxicity of intravitreal tacrolimus. Ophthalmic Surg Lasers. 2002; 33: 140–144, [PUBMED], [INFOTRIEVE]
- Conde M, Andrade J, Bedoya F J, Santa Maria C, Sobrino F. Inhibitory effect of cyclosporin A and FK506 on nitric oxide production by cultured macrophages. Evidence of a direct effect on nitric oxide synthase activity. Immunology. 1995; 84: 476–481, [PUBMED], [INFOTRIEVE]
- Kaplan H J, Diamond J G, Brown S A. Vitrectomy in experimental uveitis. I. Operative technique in rabbits. Arch Ophthalmol. 1979; 97: 331–335, [PUBMED], [INFOTRIEVE]
- Sakurai E, Nozaki M, Okabe K, Kunou N, Kimura H, Ogura Y. Scleral plug of biodegradable polymers containing tacrolimus (FK506) for experimental uveitis. Invest Ophthalmol Vis Sci. 2003; 44: 4845–4852, [PUBMED], [INFOTRIEVE]