REFERENCES
- Battegay E J. Angiogenesis: mechanistic insights, neovascular diseases, and therapeutic prospects. J Mol Med. 1995; 73: 333–346, [PUBMED], [INFOTRIEVE], [CSA]
- Moss S E, Klein R, Klein B E. The 14-year incidence of visual loss in a diabetic population. Ophthalmology. 1998; 105: 998–1003, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Bossi E, Koerner F. Retinopathy of prematurity. Intensive Care Med. 1995; 21: 241–246, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Klein R. Diabetic retinopathy. Annu Rev Public Health. 1996; 17: 137–158, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Cunha-Vaz J G, Gray J R, Zeimer R C, Mota M C, Ishimoto B M, Leite E. Characterization of the early stages of diabetic retinopathy by vitreous fluorophotometry. Diabetes. 1985; 34: 53–59, [PUBMED], [INFOTRIEVE]
- Yoshida A, Ishiko S, Kojima M, Ogasawara H. Permeability of the blood-ocular barrier in adolescent and adult diabetic patients. Br J Ophthalmol. 1993; 77: 158–161, [PUBMED], [INFOTRIEVE]
- Hammes H P, Lin J, Bretzel R G, Brownlee M, Breier G. Upregulation of the vascular endothelial growth factor/vascular endothelial growth factor receptor system in experimental background diabetic retinopathy of the rat. Diabetes. 1998; 47: 401–406, [PUBMED], [INFOTRIEVE]
- Murata T, Nakagawa K, Khalil A, Ishibashi T, Inomata H, Sueishi K. The relation between expression of vascular endothelial growth factor and breakdown of the blood-retinal barrier in diabetic rat retinas. Lab Invest 1996; 74: 819–825, [PUBMED], [INFOTRIEVE], [CSA]
- Adamis A P, Miller J W, Bernal M T, D'Amico D J, Folkman J, Yeo T K, Yeo K T. Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy. Am J Ophthalmol. 1994; 118: 445–450, [PUBMED], [INFOTRIEVE], [CSA]
- Aiello L P, Bursell S E, Clermont A, Duh E, Ishii H, Takagi C, Mori F, Ciulla T A, Ways K, Jirousek M, et al. Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta-isoform-selective inhibitor. Diabetes 1997; 46: 1473–1480, [PUBMED], [INFOTRIEVE]
- Aiello L P, Wong J S. Role of vascular endothelial growth factor in diabetic vascular complications. Kidney Int Suppl. 2000; 77: S113–119, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Antonetti D A, Lieth E, Barber A J, Gardner T W. Molecular mechanisms of vascular permeability in diabetic retinopathy. Semin Ophthalmol. 1999; 14: 240–248, [PUBMED], [INFOTRIEVE], [CSA]
- Dvorak H F. VPF/VEGF and the angiogenic response. Semin Perinatol. 2000; 24: 75–78, [PUBMED], [INFOTRIEVE], [CSA]
- Qaum T, Xu Q, Joussen A M, Clemens M W, Qin W, Miyamoto K, Hassessian H, Wiegand S J, Rudge J, Yancopoulos G D, et al. VEGF-initiated blood-retinal barrier breakdown in early diabetes. Invest Ophthalmol Vis Sci. 2001; 42: 2408–2413, [PUBMED], [INFOTRIEVE], [CSA]
- Ji W R, Barrientos L G, Llinas M, Gray H, Villarreal X, DeFord M E, Castellino F J, Kramer R A, Trail P A. Selective inhibition by kringle 5 of human plasminogen on endothelial cell migration, an important process in angiogenesis. Biochem Biophys Res Commun. 1998; 247: 414–419, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Lu H, Dhanabal M, Volk R, Waterman M J, Ramchandran R, Knebelmann B, Segal M, Sukhatme V P. Kringle 5 causes cell cycle arrest and apoptosis of endothelial cells. Biochem Biophys Res Commun. 1999; 258: 668–673, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Chang Y, Mochalkin I, McCance S G, Cheng B, Tulinsky A, Castellino F J. Structure and ligand binding determinants of the recombinant kringle 5 domain of human plasminogen. Biochemistry. 1998; 37: 3258–3271, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Castellino F J, McCance S G. The kringle domains of human plasminogen. Ciba Found Symp. 1997; 212: 46–60, [PUBMED], [INFOTRIEVE], [CSA]
- Cao Y, Chen A, An S S, Ji R W, Davidson D, Llinas M. Kringle 5 of plasminogen is a novel inhibitor of endothelial cell growth. J Biol Chem. 1997; 272: 22924–22928, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Abumiya T, Lucero J, Heo J H, Tagaya M, Koziol J A, Copeland B R, del Zoppo G J. Activated microvessels express vascular endothelial growth factor and integrin alpha(v)beta3 during focal cerebral ischemia. J Cereb Blood Flow Metab. 1999; 19: 1038–1050, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Zhang D, Kaufman P L, Gao G, Saunders R A, Ma J X. Intravitreal injection of plasminogen kringle 5, an endogenous angiogenic inhibitor, arrests retinal neovascularization in rats. Diabetologia. 2001; 44: 757–765, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Gao G, Li Y, Gee S, Dudley A, Fant J, Crosson C, Ma J-X. Down-regulation of VEGF and up-regulation of PEDF: a possible mechanism for the anti-angiogenic activity of plasminogen kringle 5. J Biol Chem. 2002; 277: 9492–9497, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Cao Y, Ji R W, Davidson D, Schaller J, Marti D, Sohndel S, McCance S G, O'Reilly M S, Llinas M, Folkman J. Kringle domains of human angiostatin. Characterization of the anti-proliferative activity on endothelial cells. J Biol Chem. 1996; 271: 29461–29467, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Zhang S X, Sima J, Shao C, Fant J, Chen Y, Rohrer B, Gao G, Ma J-x. Plasminogen kringle 5 reduces vascular leakage in the retina of rat model of the oxygen-induced retinopathy and diabetes. Diabetologia. 2004; 47: 124–131, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Kurz D, Ciulla T A. Novel approaches for retinal drug delivery. Ophthalmol Clin North Am. 2002; 15: 405–410, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Geroski D H, Edelhauser H F. Transscleral drug delivery for posterior segment disease. Adv Drug Deliv Rev. 2001; 52: 37–48, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Maurice D. Review: practical issues in intravitreal drug delivery. J Ocul Pharmacol Ther. 2001; 17: 393–401, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Tojo K, Isowaki A. Pharmacokinetic model for in vivo/in vitro correlation of intravitreal drug delivery. Adv Drug Deliv Rev. 2001; 52: 17–24, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Ambati J, Gragoudas E S, Miller J W, You T T, Miyamoto K, Delori F C, Adamis A P. Transscleral delivery of bioactive protein to the choroid and retina. Invest Ophthalmol Vis Sci. 2000; 41: 1186–1191, [PUBMED], [INFOTRIEVE], [CSA]
- Loewenstein A, Zemel E, Vered Y, Lazar M, Perlman I. Retinal toxicity of gentamicin after subconjunctival injection performed adjacent to thinned sclera. Ophthalmology. 2001; 108: 759–764, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Einmahl S, Savoldelli M, D'Hermies F, Tabatabay C, Gurny R, Behar-Cohen F. Evaluation of a novel biomaterial in the suprachoroidal space of the rabbit eye. Invest Ophthalmol Vis Sci. 2002; 43: 1533–1539, [PUBMED], [INFOTRIEVE], [CSA]
- Yanagi Y, Tamaki Y, Obata R, Muranaka K, Homma N, Matsuoka H, Mano H. Subconjunctival administration of bucillamine suppresses choroidal neovascularization in rat. Invest Ophthalmol Vis Sci. 2002; 43: 3495–3499, [PUBMED], [INFOTRIEVE], [CSA]
- Maurice D M. Drug delivery to the posterior segment from drops. Surv Ophthalmol 2002; 47: S41–52, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Koevary S B. Pharmacokinetics of topical ocular drug delivery: potential uses for the treatment of diseases of the posterior segment and beyond. Curr Drug Metab. 2003; 4: 213–222, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Smith L E, Wesolowski E, McLellan A, Kostyk S K, D'Amato R, Sullivan R, D'Amore P A. Oxygen-induced retinopathy in the mouse. Invest Ophthalmol Vis Sci. 1994; 35: 101–111, [PUBMED], [INFOTRIEVE]
- Gao G, Li Y, Fant J, Crosson C E, Becerra S P, Ma J X. Difference in ischemic regulation of vascular endothelial growth factor and pigment epithelium–derived factor in brown norway and sprague dawley rats contributing to different susceptibilities to retinal neovascularization. Diabetes. 2002; 51: 1218–1225, [PUBMED], [INFOTRIEVE]
- Xu Q, Qaum T, Adamis A P. Sensitive blood-retinal barrier breakdown quantitation using Evans blue. Invest Ophthalmol Vis Sci. 2001; 42: 789–794, [PUBMED], [INFOTRIEVE], [CSA]
- Radius R L, Anderson D R. Distribution of albumin in the normal monkey eye as revealed by Evans blue fluorescence microscopy. Invest Ophthalmol Vis Sci. 1980; 19: 238–243, [PUBMED], [INFOTRIEVE]
- Rohrer B, Stell W K. Localization of putative dopamine D2-like receptors in the chick retina, using in situ hybridization and immunocytochemistry. Brain Res. 1995; 695: 110–116, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Ambati J, Adamis A P. Transscleral drug delivery to the retina and choroid. Prog Retin Eye Res. 2002; 21: 145–151, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Frohlich E. [Structure and function of blood-tissue barriers]. Dtsch Med Wochenschr. 2002; 127: 2629–2634, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]